Sphingosine kinase-1 protects differentiated N2a cells against beta-amyloid25-35-induced neurotoxicity via the mitochondrial pathway

Neurochemical Research

Volumn 39, Issue 5, 2014, Pages 932-940

  Yang, Yang ^a,b   Wang, Min ^a   Lv, Bingjie ^b   Ma, Rong ^c   Hu, Jing ^a   Dun, Yaoyan ^c   Sun, Shenggang ^a   Li, Gang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b BINZHOU MEDICAL UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Alzheimer's disease; Beta amyloid; Neuro 2a cells; Sphingosine kinase 1

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CERAMIDE; PROTEIN BAX; PROTEIN BCL 2; SPHINGOSINE KINASE 1; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT; PHOSPHOTRANSFERASE; SPHINGOSINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DISEASE EXACERBATION; INTRACELLULAR SIGNALING; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; DRUG EFFECTS; HUMAN; METABOLISM; MITOCHONDRION; NEUROTOXICITY SYNDROMES; PC12 CELL LINE; RAT; TOXICITY;

AMYLOID BETA-PEPTIDES; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; HUMANS; MICE; MITOCHONDRIA; NEUROTOXICITY SYNDROMES; PC12 CELLS; PEPTIDE FRAGMENTS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS;

EID: 84905406924     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1290-6     Document Type: Article

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