The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner

Cellular Signalling

Volumn 23, Issue 7, 2011, Pages 1144-1152

  Kumar, Ashok ^a   Byun, Hoe Sup ^b   Bittman, Robert ^b   Saba, Julie D ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Fatty aldehyde; Hexadecenal; JNK; S1P lyase; Sphingolipid; Sphingosine 1 phosphate

Indexed keywords

ACETYLCYSTEINE; BIOLOGICAL PRODUCT; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BID; PROTEIN C JUN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE LYASE; STRESS ACTIVATED PROTEIN KINASE; TRANS 2 HEXADECENAL; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; ENZYME RELEASE; FATTY ACID METABOLISM; FLOW CYTOMETRY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LIPID DEGRADATION; MITOCHONDRION; MOUSE; NONHUMAN; OLEFINATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ALDEHYDES; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CDC42 GTP-BINDING PROTEIN; CYTOSKELETON; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HEK293 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASES; MEMBRANE PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NIH 3T3 CELLS; PHALLOIDINE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPHINGOLIPIDS;

MURINAE;

EID: 79954419484     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.02.009     Document Type: Article

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