Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet-fed mice

Diabetes

Volumn 61, Issue 12, 2012, Pages 3148-3155

  Bruce, Clinton R ^a,b   Risis, Steve ^a   Babb, Joanne R ^a   Yang, Christine ^a   Kowalski, Greg M ^b   Selathurai, Ahrathy ^b   Lee Young, Robert S ^a   Weir, Jacquelyn M ^a   Yoshioka, Kazuaki ^c   Takuwa, Yoh ^c   Meikle, Peter J ^a   Pitson, Stuart M ^d   Febbraio, Mark A ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c KANAZAWA UNIVERSITY   (Japan)

^d CENTRE FOR CANCER BIOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; INSULIN; SPHINGOSINE KINASE 1; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FAT; BODY MASS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CERAMIDES; DIET, HIGH-FAT; INSULIN RESISTANCE; MICE; MUSCLE, SKELETAL; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYMERASE CHAIN REACTION;

EID: 84870341562     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0029     Document Type: Article

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