Essential role for sphingosine kinases in neural and vascular development

Molecular and Cellular Biology

Volumn 25, Issue 24, 2005, Pages 11113-11121

  Mizugishi, Kiyomi ^a   Yamashita, Tadashi ^a   Olivera, Ana ^b   Miller, Georgina F ^c   Spiegel, Sarah ^d   Proia, Richard L ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SPHINGOLIPID; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR SYSTEM; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; DEVELOPMENT; EMBRYO; EMBRYO DEATH; METABOLITE; MITOSIS; MOUSE; MOUSE MUTANT; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOOD VESSELS; LYSOPHOSPHOLIPIDS; MICE; MICE, KNOCKOUT; MITOSIS; NEOVASCULARIZATION, PHYSIOLOGIC; NERVOUS SYSTEM; NEURAL TUBE DEFECTS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE;

ANIMALIA;

EID: 28544437478     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.24.11113-11121.2005     Document Type: Article

References (31)

1. 1 acts within endothelial cells to regulate vascular maturation. Blood 102:3665-3667.
2. 1, on T-cells controls thymic emigration. J. Biol. Chem. 279:15396-15401.
3. Allende, M. L., T. Sasaki, H. Kawai, A. Olivera, Y. Mi, G. van Echten-Deckert, R. Hajdu, M. Rosenbach, C. A. Keohane, S. Mandala, S. Spiegel, and R. L. Proia. 2004. Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. J. Biol. Chem. 279:52487-52492.
4. Bamforth, S. D., J. Bragança, J. Eloranta, J. N. Murdoch, F. I. Marques, K. R. Kranc, H. Farza, D. J. Henderson, H. C. Hurst, and S. Bhattacharya. 2001. Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat. Genet. 29:469-474.
5. Cinamon, G., M. Matloubian, M. J. Lesneski, Y. Xu, C. Low, T. Lu, R. L. Proia, and J. G. Cyster. 2004. Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat. Immunol. 5:713-720.
6. Copp, A. J., N. D. Greene, and J. N. Murdoch. 2003. The genetic basis of mammalian neurulation. Nat. Rev. Genet. 4:784-793.
7. Coursol, S., L. M. Fan, H. Stunff, S. Spiegel, S. Gilroy, and S. M. Assmann. 2003. Sphingolipid signaling in Arabidopsis guard cells involves heterotrimeric G proteins. Nature 423:651-654.
8. Cuvillier, O., G. Pirianov, B. Kleuser, P. G. Vanek, O. A. Coso, S. Gutkind, and S. Spiegel. 1996. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 381:800-803.
9. Edsall, L. C., and S. Spiegel. 1999. Enzymatic measurement of sphingosine 1-phosphate. Anal. Biochem. 272:80-86.
10. Gowen, L. C., B. L. Johnson, A. M. Latour, K. K. Sulik, and B. H. Koller. 1996. Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat. Genet. 12:191-194.
11. Hla, T., M. J. Lee, N. Ancellin, J. H. Paik, and M. J. Kluk. 2001. Lysophospholipids-receptor revelations. Science 294:1875-1878.
12. Igarashi, N., T. Okada, S. Hayashi, T. Fujita, S. Jahangeer, and S. Nakamura. 2003. Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis. J. Biol. Chem. 278:46832-46839.
13. Kohama, T., A. Olivera, L. Edsall, M. M. Nagiec, R. Dickson, and S. Spiegel. 1998. Molecular cloning and functional characterization of murine sphingosine kinase. J. Biol. Chem. 273:23722-23728.
14. 3 function coordinately during embryonic angiogenesis. J. Biol. Chem. 279:29367-29373.
15. Kupperman, E., S. An, N. Osborne, S. Waldron, and D. Y. Stainier. 2000. A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. Nature 406:192-195.
16. Lee, M. J., S. Thangada, K. P. Claffey, N. Ancellin, C. H. Liu, M. Kluk, M. Volpi, R. I. Sha'afi, and T. Hla. 1999. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell 99:301-312.
17. Liu, H., M. Sugiura, V. E. Nava, L. C. Edsall, K. Kono, S. Poulton, S. Milstien, T. Kohama, and S. Spiegel. 2000. Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform. J. Biol. Chem. 275:19513-19520.
18. Liu, Y., R. Wada, T. Yamashita, Y. Mi, C. X. Deng, J. P. Hobson, H. M, Rosenfeldt, V. E. Nava, S, S. Chae, M. J. Lee, C. H. Liu, T. Hla, S. Spiegel, and R. L. Proia. 2000. Edg-1, the G-protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Investig. 106:951-961.
19. Liu, H., R. E. Toman, S. K. Goparaju, M. Maceyka, V. E. Nava, H. Sankala, S. G. Payne, M. Bektas, I. Ishii, J. Chun, S. Milstien, and S. Spiegel. 2003. Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis. J. Biol. Chem. 278:40330-40336.
20. Marasas, W. F., R. T. Riley, K. A. Hendricks, V. L. Stevens, T. W. Sadler, J. Gelineau-van Waes, S. A. Missmer, J. Cabrera, O. Torres, W. C. Gelderblom, J. Allegood, C. Martínez, J. Maddox, J. D. Miller, L. Starr, M. C. Sullards, A. V. Roman, K. A. Voss, E. Wang, and A. H. Merrill, Jr. 2004. Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. J. Nutr. 134:711-716.
21. Matloubian, M., C. G. Lo, G. Cinamon, M. J. Lesneski, Y. Xu, V. Brinkmann, M. L. Allende, R. L. Proia, and J. G. Cyster. 2004. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427:355-360.
22. 1-3 in angiogenesis. FEBS Lett. 531:103-108.
23. Morita, Y., G. I. Perez, F. Paris, S. R. Miranda, D. Ehleiter, A. Haimovitz-Friedman, Z. Fuks, Z. Xie, J. C. Reed, E. H. Schuchman, R. N. Kolesnick, and J. L. Tilly. 2000. Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. Nat. Med. 6:1109-1114.
24. Olivera, A., and S. Spiegel. 1993. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365:557-560.
25. Olivera, A., T. Kohama, Z. Tu, S. Milstien, and S. Spiegel. 1998. Purification and characterization of rat kidney sphingosine kinase. J. Biol. Chem. 273: 12576-12583.
26. Olivera, A., T. Kohama, L. Edsall, V. Nava, O. Cuvillier, S. Poulton, and S. Spiegel. 1999. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. J. Cell Biol. 147:545-558.
27. 12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. J. Biol. Chem. 278:46452-46460.
28. Ruland, J., G. S. Duncan, A. Elia, I. del Barco Barrantes, L. Nguyen, S. Plyte, D. G. Millar, D. Bouchard, A. Wakeham, P. S. Ohashi, and T. W. Mak. 2001. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure. Cell 104:33-42.
29. Spiegel, S., and S. Milstien. 2003. Sphingosine-1-phosphate: an enigmatic signaling lipid. Nat. Rev. Mol. Cell Biol. 4:397-407.
30. Storkebaum, E., D. Lambrechts, and P. Carmeliet. 2004. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 26:943-954.
31. Wilkinson, D. G. 1992. In situ hybridization: a practical approach. IRL Press, Oxford, United Kingdom.