Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: Role of s1p signaling and nox proteins

American Journal of Pathology

Volumn 183, Issue 4, 2013, Pages 1169-1182

  Harijith, Anantha ^a   Pendyala, Srikanth ^a   Reddy, Narsa M ^a   Bai, Tao ^a   Usatyuk, Peter V ^a   Berdyshev, Evgeny ^a   Gorshkova, Irina ^a   Huang, Long Shuang ^a   Mohan, Vijay ^a   Garzon, Steve ^a   Kanteti, Prasad ^a   Reddy, Sekhar P ^a   Raj, J Usha ^a   Natarajan, Viswanathan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; GENOTYPE; HUMAN; HUMAN CELL; HYPEROXIA; IN VITRO STUDY; LUNG DYSPLASIA; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUTROPHIL COUNT; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ALDEHYDE-LYASES; ANIMALS; ANIMALS, NEWBORN; BRONCHOPULMONARY DYSPLASIA; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOTHELIAL CELLS; HUMANS; HYPEROXIA; LYSOPHOSPHOLIPIDS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; NADPH OXIDASE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PNEUMONIA; PULMONARY ALVEOLI; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84884570906     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.06.018     Document Type: Article

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