메뉴 건너뛰기




Volumn 288, Issue 38, 2013, Pages 27667-27679

Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORY FUNCTION; NUCLEAR FACTORS; NUCLEAR TRANSLOCATIONS; P38 MITOGEN-ACTIVATED PROTEIN KINASE; SPHINGOLIPIDS; SPHINGOSINE 1 PHOSPHATES; SPHINGOSINE KINASE; TUMOR NECROSIS;

EID: 84884584558     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.489443     Document Type: Article
Times cited : (33)

References (70)
  • 1
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling. Lessons from sphingolipids
    • Hannun, Y. A., and Obeid, L. M. (2008) Principles of bioactive lipid signalling. Lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9, 139-150
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 3
    • 84855340424 scopus 로고    scopus 로고
    • Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury
    • Yung, L. M., Wei, Y., Qin, T., Wang, Y., Smith, C. D., and Waeber, C. (2012) Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury. Stroke 43, 199-204
    • (2012) Stroke , vol.43 , pp. 199-204
    • Yung, L.M.1    Wei, Y.2    Qin, T.3    Wang, Y.4    Smith, C.D.5    Waeber, C.6
  • 4
    • 84863116009 scopus 로고    scopus 로고
    • Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury
    • Park, S. W., Kim, M., Brown, K. M., D'Agati, V. D., and Lee, H. T. (2012) Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury. J. Am. Soc. Nephrol. 23, 266-280
    • (2012) J. Am. Soc. Nephrol. , vol.23 , pp. 266-280
    • Park, S.W.1    Kim, M.2    Brown, K.M.3    D'Agati, V.D.4    Lee, H.T.5
  • 5
    • 84880533699 scopus 로고    scopus 로고
    • Sphingosine kinase/sphingosine 1-phosphate signaling in cancer therapeutics and drug resistance
    • Selvam, S. P., and Ogretmen, B. (2013) Sphingosine kinase/sphingosine 1-phosphate signaling in cancer therapeutics and drug resistance. Handb. Exp. Pharmacol. 216, 3-27
    • (2013) Handb. Exp. Pharmacol. , vol.216 , pp. 3-27
    • Selvam, S.P.1    Ogretmen, B.2
  • 8
    • 84862188843 scopus 로고    scopus 로고
    • Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells
    • Hisano, Y., Kobayashi, N., Yamaguchi, A., and Nishi, T. (2012) Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. PLoS One 7, e38941
    • (2012) PLoS One , vol.7
    • Hisano, Y.1    Kobayashi, N.2    Yamaguchi, A.3    Nishi, T.4
  • 10
    • 84884211437 scopus 로고    scopus 로고
    • Dissecting the role of the S1P/S1PR axis in health and disease
    • Aarthi, J. J., Darendeliler, M. A., and Pushparaj, P. N. (2011) Dissecting the role of the S1P/S1PR axis in health and disease. J. Dent. Res. 90, 841-854
    • (2011) J. Dent. Res. , vol.90 , pp. 841-854
    • Aarthi, J.J.1    Darendeliler, M.A.2    Pushparaj, P.N.3
  • 12
    • 4544319815 scopus 로고    scopus 로고
    • Molecular mechanisms of TNF-α-induced ceramide formation in human glioma cells. P53-mediated oxidant stressdependent and -independent pathways
    • Sawada, M., Kiyono, T., Nakashima, S., Shinoda, J., Naganawa, T., Hara, S., Iwama, T., and Sakai, N. (2004) Molecular mechanisms of TNF-α-induced ceramide formation in human glioma cells. p53-mediated oxidant stressdependent and -independent pathways. Cell Death Differ. 11, 997-1008
    • (2004) Cell Death Differ. , vol.11 , pp. 997-1008
    • Sawada, M.1    Kiyono, T.2    Nakashima, S.3    Shinoda, J.4    Naganawa, T.5    Hara, S.6    Iwama, T.7    Sakai, N.8
  • 13
    • 0035399943 scopus 로고    scopus 로고
    • TNF-α-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes
    • Osawa, Y., Banno, Y., Nagaki, M., Brenner, D. A., Naiki, T., Nozawa, Y., Nakashima, S., and Moriwaki, H. (2001) TNF-α-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. J. Immunol. 167, 173-180
    • (2001) J. Immunol. , vol.167 , pp. 173-180
    • Osawa, Y.1    Banno, Y.2    Nagaki, M.3    Brenner, D.A.4    Naiki, T.5    Nozawa, Y.6    Nakashima, S.7    Moriwaki, H.8
  • 14
    • 79953213300 scopus 로고    scopus 로고
    • Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells
    • Clarke, C. J., Cloessner, E. A., Roddy, P. L., and Hannun, Y. A. (2011) Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells. Biochem. J. 435, 381-390
    • (2011) Biochem. J. , vol.435 , pp. 381-390
    • Clarke, C.J.1    Cloessner, E.A.2    Roddy, P.L.3    Hannun, Y.A.4
  • 15
    • 33847719144 scopus 로고    scopus 로고
    • Role for neutral sphingomyelinase-2 in tumor necrosis factor α-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells. P38 MAPK is an upstream regulator of nSMase2
    • Clarke, C. J., Truong, T. G., and Hannun, Y. A. (2007) Role for neutral sphingomyelinase-2 in tumor necrosis factor α-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells. p38 MAPK is an upstream regulator of nSMase2. J. Biol. Chem. 282, 1384-1396
    • (2007) J. Biol. Chem. , vol.282 , pp. 1384-1396
    • Clarke, C.J.1    Truong, T.G.2    Hannun, Y.A.3
  • 17
    • 64249130618 scopus 로고    scopus 로고
    • The unexpected pleiotropic activities of RANTES
    • Levy, J. A. (2009) The unexpected pleiotropic activities of RANTES. J. Immunol. 182, 3945-3946
    • (2009) J. Immunol. , vol.182 , pp. 3945-3946
    • Levy, J.A.1
  • 18
    • 0030513850 scopus 로고    scopus 로고
    • Fibroblasts but not epithelial cells obtained from human nasal mucosa produce the chemokine RANTES
    • Maune, S., Berner, I., Sticherling, M., Kulke, R., Bartels, J., and Schröder, J. M. (1996) Fibroblasts but not epithelial cells obtained from human nasal mucosa produce the chemokine RANTES. Rhinology 34, 210-214
    • (1996) Rhinology , vol.34 , pp. 210-214
    • Maune, S.1    Berner, I.2    Sticherling, M.3    Kulke, R.4    Bartels, J.5    Schröder, J.M.6
  • 25
    • 33847321490 scopus 로고    scopus 로고
    • Mechanisms of disease. Regulation of RANTES (CCL5) in renal disease
    • Krensky, A. M., and Ahn, Y. T. (2007) Mechanisms of disease. Regulation of RANTES (CCL5) in renal disease. Nat. Clin. Pract Nephrol. 3, 164-170
    • (2007) Nat. Clin. Pract Nephrol. , vol.3 , pp. 164-170
    • Krensky, A.M.1    Ahn, Y.T.2
  • 26
    • 0032865441 scopus 로고    scopus 로고
    • Relationship between serum RANTES levels and radiological progression in rheumatoid arthritis patients treated with methotrexate
    • Boiardi, L., Macchioni, P., Meliconi, R., Pulsatelli, L., Facchini, A., and Salvarani, C. (1999) Relationship between serum RANTES levels and radiological progression in rheumatoid arthritis patients treated with methotrexate. Clin. Exp. Rheumatol. 17, 419-425
    • (1999) Clin. Exp. Rheumatol. , vol.17 , pp. 419-425
    • Boiardi, L.1    Macchioni, P.2    Meliconi, R.3    Pulsatelli, L.4    Facchini, A.5    Salvarani, C.6
  • 28
    • 60749124122 scopus 로고    scopus 로고
    • The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules
    • Hao, S., and Baltimore, D. (2009) The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules. Nat. Immunol. 10, 281-288
    • (2009) Nat. Immunol. , vol.10 , pp. 281-288
    • Hao, S.1    Baltimore, D.2
  • 31
    • 0036009461 scopus 로고    scopus 로고
    • Tumor necrosis factor-α-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells. Modulation by glucocorticoids and β-agonists
    • Ammit, A. J., Lazaar, A. L., Irani, C., O'Neill, G. M., Gordon, N. D., Amrani, Y., Penn, R. B., and Panettieri, R. A., Jr. (2002) Tumor necrosis factor-α-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells. Modulation by glucocorticoids and β-agonists. Am. J. Respir. Cell Mol. Biol. 26, 465-474
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.26 , pp. 465-474
    • Ammit, A.J.1    Lazaar, A.L.2    Irani, C.3    O'Neill, G.M.4    Gordon, N.D.5    Amrani, Y.6    Penn, R.B.7    Panettieri Jr., R.A.8
  • 32
    • 60549095703 scopus 로고    scopus 로고
    • JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1
    • Kumar, D., Hosse, J., Von Toerne, C., Noessner, E., and Nelson, P. J. (2009) JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1. J. Immunol. 182, 1011-1020
    • (2009) J. Immunol. , vol.182 , pp. 1011-1020
    • Kumar, D.1    Hosse, J.2    Von Toerne, C.3    Noessner, E.4    Nelson, P.J.5
  • 33
    • 33644980666 scopus 로고    scopus 로고
    • Molecular mechanisms for the release of chemokines from human leukemic mast cell line (HMC)-1 cells activated by SCF and TNF-α. Roles of ERK, p38 MAPK, and NF-κB
    • Wong, C. K., Tsang, C. M., Ip, W. K., and Lam, C. W. (2006) Molecular mechanisms for the release of chemokines from human leukemic mast cell line (HMC)-1 cells activated by SCF and TNF-α. Roles of ERK, p38 MAPK, and NF-κB. Allergy 61, 289-297
    • (2006) Allergy , vol.61 , pp. 289-297
    • Wong, C.K.1    Tsang, C.M.2    Ip, W.K.3    Lam, C.W.4
  • 34
    • 84856091925 scopus 로고    scopus 로고
    • Regulation of CCL5 expression in smooth muscle cells following arterial injury
    • Liu, H., Ning, H., Men, H., Hou, R., Fu, M., Zhang, H., and Liu, J. (2012) Regulation of CCL5 expression in smooth muscle cells following arterial injury. PLoS One 7, e30873
    • (2012) PLoS One , vol.7
    • Liu, H.1    Ning, H.2    Men, H.3    Hou, R.4    Fu, M.5    Zhang, H.6    Liu, J.7
  • 36
    • 77957804651 scopus 로고    scopus 로고
    • Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation. Probing sphingolipid signaling at the outer plasma membrane
    • Canals, D., Jenkins, R. W., Roddy, P., Hernández-Corbacho, M. J., Obeid, L. M., and Hannun, Y. A. (2010) Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation. Probing sphingolipid signaling at the outer plasma membrane. J. Biol. Chem. 285, 32476-32485
    • (2010) J. Biol. Chem. , vol.285 , pp. 32476-32485
    • Canals, D.1    Jenkins, R.W.2    Roddy, P.3    Hernández-Corbacho, M.J.4    Obeid, L.M.5    Hannun, Y.A.6
  • 37
    • 84886101285 scopus 로고    scopus 로고
    • Roles, regulation and inhibitors of sphingosine kinase 2
    • Neubauer, H. A., and Pitson, S. M. (2013) Roles, regulation and inhibitors of sphingosine kinase 2. FEBS J., in press
    • (2013) FEBS J., in Press
    • Neubauer, H.A.1    Pitson, S.M.2
  • 40
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce, J. W., Schoenleber, R., Jesmok, G., Best, J., Moore, S. A., Collins, T., and Gerritsen, M. E. (1997) Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J. Biol. Chem. 272, 21096-21103
    • (1997) J. Biol. Chem. , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerritsen, M.E.7
  • 42
    • 82955233198 scopus 로고    scopus 로고
    • Regulation of TNFinduced NF-κB activation by different cytoplasmic ubiquitination events
    • Verhelst, K., Carpentier, I., and Beyaert, R. (2011) Regulation of TNFinduced NF-κB activation by different cytoplasmic ubiquitination events. Cytokine Growth Factor Rev. 22, 277-286
    • (2011) Cytokine Growth Factor Rev. , vol.22 , pp. 277-286
    • Verhelst, K.1    Carpentier, I.2    Beyaert, R.3
  • 44
    • 33749265867 scopus 로고    scopus 로고
    • The alternative NF-κB pathway from biochemistry to biology. Pitfalls and promises for future drug development
    • Dejardin, E. (2006) The alternative NF-κB pathway from biochemistry to biology. Pitfalls and promises for future drug development. Biochem. Pharmacol. 72, 1161-1179
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1161-1179
    • Dejardin, E.1
  • 45
    • 33745507931 scopus 로고    scopus 로고
    • TNF-α mediates p38MAPkinase activation and negatively regulates bone formation at the injured growth plate in rats
    • Zhou, F. H., Foster, B. K., Zhou, X. F., Cowin, A. J., and Xian, C. J. (2006) TNF-α mediates p38MAPkinase activation and negatively regulates bone formation at the injured growth plate in rats. J. Bone Miner Res. 21, 1075-1088
    • (2006) J. Bone Miner Res. , vol.21 , pp. 1075-1088
    • Zhou, F.H.1    Foster, B.K.2    Zhou, X.F.3    Cowin, A.J.4    Xian, C.J.5
  • 46
    • 33845401233 scopus 로고    scopus 로고
    • Regulation of TNF mediated antiapoptotic signaling in human neutrophils. Role of δ-PKC and ERK1/2
    • Kilpatrick, L. E., Sun, S., Mackie, D., Baik, F., Li, H., and Korchak, H. M. (2006) Regulation of TNF mediated antiapoptotic signaling in human neutrophils. Role of δ-PKC and ERK1/2. J. Leukocyte Biol. 80, 1512-1521
    • (2006) J. Leukocyte Biol. , vol.80 , pp. 1512-1521
    • Kilpatrick, L.E.1    Sun, S.2    Mackie, D.3    Baik, F.4    Li, H.5    Korchak, H.M.6
  • 47
    • 79953691103 scopus 로고    scopus 로고
    • Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9
    • Schenten, V., Melchior, C., Steinckwich, N., Tschirhart, E. J., and Bréchard, S. (2011) Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9. J. Leukocyte Biol. 89, 587-596
    • (2011) J. Leukocyte Biol. , vol.89 , pp. 587-596
    • Schenten, V.1    Melchior, C.2    Steinckwich, N.3    Tschirhart, E.J.4    Bréchard, S.5
  • 48
    • 0032885060 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate induces heat shock protein 27 via p38 mitogen-activated protein kinase activation in osteoblasts
    • Kozawa, O., Niwa, M., Matsuno, H., Tokuda, H., Miwa, M., Ito, H., Kato, K., and Uematsu, T. (1999) Sphingosine 1-phosphate induces heat shock protein 27 via p38 mitogen-activated protein kinase activation in osteoblasts. J. Bone Miner. Res. 14, 1761-1767
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 1761-1767
    • Kozawa, O.1    Niwa, M.2    Matsuno, H.3    Tokuda, H.4    Miwa, M.5    Ito, H.6    Kato, K.7    Uematsu, T.8
  • 50
    • 3142777716 scopus 로고    scopus 로고
    • Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-β
    • Kim, M. O., Suh, H. S., Brosnan, C. F., and Lee, S. C. (2004) Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-β. J. Neurochem. 90, 297-308
    • (2004) J. Neurochem. , vol.90 , pp. 297-308
    • Kim, M.O.1    Suh, H.S.2    Brosnan, C.F.3    Lee, S.C.4
  • 51
    • 0042854776 scopus 로고    scopus 로고
    • Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor κB and interferon regulatory factor 3
    • Melchjorsen, J., and Paludan, S. R. (2003) Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor κB and interferon regulatory factor 3. J. Gen Virol. 84, 2491-2495
    • (2003) J. Gen Virol. , vol.84 , pp. 2491-2495
    • Melchjorsen, J.1    Paludan, S.R.2
  • 52
    • 80054990842 scopus 로고    scopus 로고
    • A possible mechanism for hepatotoxicity induced by BIRB-796, an orally active p38 mitogen-activated protein kinase inhibitor
    • Iwano, S., Asaoka, Y., Akiyama, H., Takizawa, S., Nobumasa, H., Hashimoto, H., and Miyamoto, Y. (2011) A possible mechanism for hepatotoxicity induced by BIRB-796, an orally active p38 mitogen-activated protein kinase inhibitor. J. Appl Toxicol. 31, 671-677
    • (2011) J. Appl Toxicol. , vol.31 , pp. 671-677
    • Iwano, S.1    Asaoka, Y.2    Akiyama, H.3    Takizawa, S.4    Nobumasa, H.5    Hashimoto, H.6    Miyamoto, Y.7
  • 53
    • 1642423481 scopus 로고    scopus 로고
    • P38 MAPK-induced nuclear factor-κB activity is required for skeletal muscle differentiation. Role of interleukin-6
    • Baeza-Raja, B., and Muñoz-Cánoves, P. (2004) p38 MAPK-induced nuclear factor-κB activity is required for skeletal muscle differentiation. Role of interleukin-6. Mol. Biol. Cell 15, 2013-2026
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2013-2026
    • Baeza-Raja, B.1    Muñoz-Cánoves, P.2
  • 54
    • 0034604623 scopus 로고    scopus 로고
    • P38 MAPK and NF-κB collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system
    • Craig, R., Larkin, A., Mingo, A. M., Thuerauf, D. J., Andrews, C., Mc-Donough, P. M., and Glembotski, C. C. (2000) p38 MAPK and NF-κB collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. J. Biol. Chem. 275, 23814-23824
    • (2000) J. Biol. Chem. , vol.275 , pp. 23814-23824
    • Craig, R.1    Larkin, A.2    Mingo, A.M.3    Thuerauf, D.J.4    Andrews, C.5    Mc-Donough, P.M.6    Glembotski, C.C.7
  • 58
    • 0029983730 scopus 로고    scopus 로고
    • The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
    • Beyaert, R., Cuenda, A., Vanden Berghe, W., Plaisance, S., Lee, J. C., Haegeman, G., Cohen, P., and Fiers, W. (1996) The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J. 15, 1914-1923
    • (1996) EMBO J. , vol.15 , pp. 1914-1923
    • Beyaert, R.1    Cuenda, A.2    Vanden Berghe, W.3    Plaisance, S.4    Lee, J.C.5    Haegeman, G.6    Cohen, P.7    Fiers, W.8
  • 59
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. The road ahead
    • Glass, C. K., and Witztum, J. L. (2001) Atherosclerosis. The road ahead. Cell 104, 503-516
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 60
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 MAPK signalling
    • Cuadrado, A., and Nebreda, A. R. (2010) Mechanisms and functions of p38 MAPK signalling. Biochem. J. 429, 403-417
    • (2010) Biochem. J. , vol.429 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 61
    • 33751002989 scopus 로고    scopus 로고
    • ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-κB transactivation during oxidative stress in skeletal myoblasts
    • Kefaloyianni, E., Gaitanaki, C., and Beis, I. (2006) ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-κB transactivation during oxidative stress in skeletal myoblasts. Cell Signal. 18, 2238-2251
    • (2006) Cell Signal. , vol.18 , pp. 2238-2251
    • Kefaloyianni, E.1    Gaitanaki, C.2    Beis, I.3
  • 62
    • 0037451357 scopus 로고    scopus 로고
    • Transcriptional activation of the NF-κB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1)
    • Vermeulen, L., De Wilde, G., Van Damme, P., Vanden Berghe, W., and Haegeman, G. (2003) Transcriptional activation of the NF-κB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1). EMBO J. 22, 1313-1324
    • (2003) EMBO J. , vol.22 , pp. 1313-1324
    • Vermeulen, L.1    De Wilde, G.2    Van Damme, P.3    Vanden Berghe, W.4    Haegeman, G.5
  • 63
    • 0036143654 scopus 로고    scopus 로고
    • P38-dependent marking of inflammatory genes for increased NF-κB recruitment
    • Saccani, S., Pantano, S., and Natoli, G. (2002) p38-dependent marking of inflammatory genes for increased NF-κB recruitment. Nat. Immunol. 3, 69-75
    • (2002) Nat. Immunol. , vol.3 , pp. 69-75
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 64
    • 4544324500 scopus 로고    scopus 로고
    • Exip, a splicing variant of p38α, participates in interleukin-1 receptor proximal complex and downregulates NF-κB pathway
    • Yagasaki, Y., Sudo, T., and Osada, H. (2004) Exip, a splicing variant of p38α, participates in interleukin-1 receptor proximal complex and downregulates NF-κB pathway. FEBS Lett. 575, 136-140
    • (2004) FEBS Lett. , vol.575 , pp. 136-140
    • Yagasaki, Y.1    Sudo, T.2    Osada, H.3
  • 65
    • 0242473165 scopus 로고    scopus 로고
    • Feedback control of the protein kinase TAK1 by SAPK2a/p38α
    • Cheung, P. C., Campbell, D. G., Nebreda, A. R., and Cohen, P. (2003) Feedback control of the protein kinase TAK1 by SAPK2a/p38α. EMBO J. 22, 5793-5805
    • (2003) EMBO J. , vol.22 , pp. 5793-5805
    • Cheung, P.C.1    Campbell, D.G.2    Nebreda, A.R.3    Cohen, P.4
  • 66
    • 84934436838 scopus 로고    scopus 로고
    • Physiological roles and mechanisms of signaling by TRAF2 and TRAF5
    • Au, P. Y., and Yeh, W. C. (2007) Physiological roles and mechanisms of signaling by TRAF2 and TRAF5. Adv. Exp. Med. Biol. 597, 32-47
    • (2007) Adv. Exp. Med. Biol. , vol.597 , pp. 32-47
    • Au, P.Y.1    Yeh, W.C.2
  • 67
    • 79958032416 scopus 로고    scopus 로고
    • The emerging role of CXCL10 in cancer (Review)
    • Liu, M., Guo, S., and Stiles, J. K. (2011) The emerging role of CXCL10 in cancer (Review). Oncol. Lett. 2, 583-589
    • (2011) Oncol. Lett. , vol.2 , pp. 583-589
    • Liu, M.1    Guo, S.2    Stiles, J.K.3
  • 68
    • 77955801617 scopus 로고    scopus 로고
    • Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro
    • Anelli, V., Gault, C. R., Snider, A. J., and Obeid, L. M. (2010) Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro. FASEB J. 24, 2727-2738
    • (2010) FASEB J. , vol.24 , pp. 2727-2738
    • Anelli, V.1    Gault, C.R.2    Snider, A.J.3    Obeid, L.M.4
  • 69
    • 67650022084 scopus 로고    scopus 로고
    • The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer
    • Ghadjar, P., Rubie, C., Aebersold, D. M., and Keilholz, U. (2009) The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer. Int. J. Cancer 125, 741-745
    • (2009) Int. J. Cancer , vol.125 , pp. 741-745
    • Ghadjar, P.1    Rubie, C.2    Aebersold, D.M.3    Keilholz, U.4
  • 70
    • 0036659130 scopus 로고    scopus 로고
    • Role of CXCL1 in tumorigenesis of melanoma
    • Dhawan, P., and Richmond, A. (2002) Role of CXCL1 in tumorigenesis of melanoma. J. Leukocyte Biol. 72, 9-18
    • (2002) J. Leukocyte Biol. , vol.72 , pp. 9-18
    • Dhawan, P.1    Richmond, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.