Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 310, Issue 2, 2016, Pages H250-H261

  Zhang, Fuyang ^a   Xia, Yunlong ^a   Yan, Wenjuan ^a   Zhang, Haoqiang ^a   Zhou, Fen ^a   Zhao, Shihao ^a   Wang, Wei ^a   Zhu, Di ^a   Xin, Chao ^a   Lee, Yan ^a   Zhang, Ling ^a   He, Yuan ^a   Gao, Erhe ^b   Tao, Ling ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac remodeling; Inflammation; Myocardial infarction; Sphingosine 1 phosphate

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; FINGOLIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LYASE; PF 543; PHOSPHOTRANSFERASE INHIBITOR; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE LYASE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE 1; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; S1PR1 PROTEIN, MOUSE; SMALL INTERFERING RNA; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CARDITIS; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE REMODELING; HEART WEIGHT; IMMUNOHISTOCHEMISTRY; LUNG WEIGHT; M MODE ECHOCARDIOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYSTOLIC DYSFUNCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE CELL; ECHOGRAPHY; GENETIC TRANSFECTION; GENETICS; HEART DISEASE; METABOLISM; MYOCARDITIS; NEWBORN; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; CYTOKINES; FINGOLIMOD HYDROCHLORIDE; HEART DISEASES; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCARDITIS; MYOCYTES, CARDIAC; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS, SPRAGUE-DAWLEY; RECEPTORS, LYSOSPHINGOLIPID; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOSINE; TRANSFECTION;

EID: 84954519467     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00372.2015     Document Type: Article

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