Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition

Thorax

Volumn 67, Issue 2, 2012, Pages 147-156

  Milara, Javier ^a,b,c   Navarro, Rafael ^a   Juan, Gustavo ^d   Peiró, Teresa ^d   Serrano, Adela ^a   Ramón, Mercedes ^a   Morcillo, Esteban ^c,d   Cortijo, Julio ^a,c,d  

^a HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^b UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBON MONOXIDE; COLLAGEN TYPE 1; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD3 PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN;

ADULT; AGED; ARTICLE; AUTOCRINE EFFECT; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FIBROSING ALVEOLITIS; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ALVEOLUS CELL TYPE 2; LUNG DIFFUSION CAPACITY; LUNG LAVAGE; MALE; MESENCHYME CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; UPREGULATION;

EID: 84856066049     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2011-200026     Document Type: Article

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