Crystal structure of Sphingosine Kinase 1 with PF-543

ACS Medicinal Chemistry Letters

Volumn 5, Issue 12, 2014, Pages 1329-1333

  Wang, Jing ^a   Knapp, Stefan ^a,b   Pyne, Nigel J ^c   Pyne, Susan ^c   Elkins, Jonathan M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

lipid; PF 543; S1P; sphingosine; SPHK1; SPHK2

Indexed keywords

CERAMIDE; ENZYME INHIBITOR; SPHINGOSINE; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 1 INHIBITOR; SPHINGOSINE KINASE 2 INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG CONFORMATION; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; STRUCTURE ANALYSIS;

EID: 84918590530     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml5004074     Document Type: Article

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