Sphingosine kinase 2 mediates cerebral preconditioning and protects the mouse brain against ischemic injury

Stroke

Volumn 43, Issue 1, 2012, Pages 199-204

  Yung, Lai Ming ^a   Wei, Ying ^a   Qin, Tao ^a   Wang, Yumei ^a   Smith, Charles D ^b   Waeber, Christian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b APOGEE BIOTECHNOLOGY CORPORATION   (United States)

Author keywords

cell death; cerebral ischemia; hypoxia; isoflurane; neurons; preconditioning; sphingosine kinase 2

Indexed keywords

ABC 294640; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOFLURANE; PHOSPHOTRANSFERASE INHIBITOR; SKI II; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION SIZE; CELL DEATH; CONTROLLED STUDY; ENZYME INDUCTION; HYPOXIA; IN VITRO STUDY; ISCHEMIC PRECONDITIONING; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; BRAIN; BRAIN ISCHEMIA; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISCHEMIC PRECONDITIONING; MALE; MICE; MICE, KNOCKOUT; NEURONS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 84855340424     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.626911     Document Type: Article

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