-
1
-
-
84910077290
-
Modeling motor neuron disease: the matter of time
-
Arbab, M., Baars, S., Geijsen, N., Modeling motor neuron disease: the matter of time. Trends Neurosci. 37 (2014), 642–652.
-
(2014)
Trends Neurosci.
, vol.37
, pp. 642-652
-
-
Arbab, M.1
Baars, S.2
Geijsen, N.3
-
2
-
-
84945942332
-
Lost in translation: pluripotent stem cell-derived hematopoiesis
-
Ackermann, M., Liebhaber, S., Klusmann, J.H., Lachmann, N., Lost in translation: pluripotent stem cell-derived hematopoiesis. EMBO Mol. Med. 7 (2015), 1388–1402.
-
(2015)
EMBO Mol. Med.
, vol.7
, pp. 1388-1402
-
-
Ackermann, M.1
Liebhaber, S.2
Klusmann, J.H.3
Lachmann, N.4
-
3
-
-
84904295147
-
Modeling human development in 3D culture
-
Ader, M., Tanaka, E.M., Modeling human development in 3D culture. Curr. Opin. Cell. Biol. 31 (2014), 23–28.
-
(2014)
Curr. Opin. Cell. Biol.
, vol.31
, pp. 23-28
-
-
Ader, M.1
Tanaka, E.M.2
-
4
-
-
84875775289
-
A modular approach to create a neurovascular unit-on-a-chip
-
Achyuta, A.K., et al. A modular approach to create a neurovascular unit-on-a-chip. Lab. chip 13 (2013), 542–553.
-
(2013)
Lab. chip
, vol.13
, pp. 542-553
-
-
Achyuta, A.K.1
-
5
-
-
84864631163
-
Genetic correction of Huntington׳s disease phenotypes in induced pluripotent stem cells
-
An, M.C., et al. Genetic correction of Huntington׳s disease phenotypes in induced pluripotent stem cells. Cell Stem Cell 11 (2012), 253–263.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 253-263
-
-
An, M.C.1
-
6
-
-
37249009271
-
Motif module map reveals enforcement of aging by continual NF-kappaB activity
-
Adler, A.S., et al. Motif module map reveals enforcement of aging by continual NF-kappaB activity. Genes. Dev. 21 (2007), 3244–3257.
-
(2007)
Genes. Dev.
, vol.21
, pp. 3244-3257
-
-
Adler, A.S.1
-
7
-
-
84859732716
-
Classic and new animal models of Parkinson׳s disease
-
Blesa, J., Phani, S., Jackson-Lewis, V., Przedborski, S., Classic and new animal models of Parkinson׳s disease. J. Biomed. Biotechnol., 2012, 2012, 845618.
-
(2012)
J. Biomed. Biotechnol.
, vol.2012
, pp. 845618
-
-
Blesa, J.1
Phani, S.2
Jackson-Lewis, V.3
Przedborski, S.4
-
8
-
-
84867839464
-
Induced pluripotent stem cells: the new patient?
-
Bellin, M., Marchetto, M.C., Gage, F.H., Mummery, C.L., Induced pluripotent stem cells: the new patient?. Nat. Rev. Mol. Cell. Biol. 13 (2012), 713–726.
-
(2012)
Nat. Rev. Mol. Cell. Biol.
, vol.13
, pp. 713-726
-
-
Bellin, M.1
Marchetto, M.C.2
Gage, F.H.3
Mummery, C.L.4
-
9
-
-
84925307610
-
Enhancing the functional maturity of induced pluripotent stem cell-derived human hepatocytes by controlled presentation of cell–cell interactions in vitro
-
Berger, D.R., Ware, B.R., Davidson, M.D., Allsup, S.R., Khetani, S.R., Enhancing the functional maturity of induced pluripotent stem cell-derived human hepatocytes by controlled presentation of cell–cell interactions in vitro. Hepatology 61 (2015), 1370–1381.
-
(2015)
Hepatology
, vol.61
, pp. 1370-1381
-
-
Berger, D.R.1
Ware, B.R.2
Davidson, M.D.3
Allsup, S.R.4
Khetani, S.R.5
-
10
-
-
55049084760
-
The mystery and magic of glia: a perspective on their roles in health and disease
-
Barres, B.A., The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 60 (2008), 430–440.
-
(2008)
Neuron
, vol.60
, pp. 430-440
-
-
Barres, B.A.1
-
11
-
-
81155131691
-
SNCA triplication Parkinson׳s patient׳s iPSC-derived DA neurons accumulate alpha-synuclein and are susceptible to oxidative stress
-
Byers, B., et al. SNCA triplication Parkinson׳s patient׳s iPSC-derived DA neurons accumulate alpha-synuclein and are susceptible to oxidative stress. PLoS One, 6, 2011, e26159.
-
(2011)
PLoS One
, vol.6
, pp. e26159
-
-
Byers, B.1
-
12
-
-
61849157257
-
Alzheimer׳s disease
-
Burns, A., Iliffe, S., Alzheimer׳s disease. BMJ, 338, 2009, b158.
-
(2009)
BMJ
, vol.338
, pp. b158
-
-
Burns, A.1
Iliffe, S.2
-
13
-
-
84882749423
-
A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells
-
Burkhardt, M.F., et al. A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells. Mol. Cell. Neurosci. 56 (2013), 355–364.
-
(2013)
Mol. Cell. Neurosci.
, vol.56
, pp. 355-364
-
-
Burkhardt, M.F.1
-
14
-
-
84859569070
-
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
-
Bilican, B., et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 5803–5808.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 5803-5808
-
-
Bilican, B.1
-
15
-
-
33745532801
-
Increased cell-to-cell variation in gene expression in ageing mouse heart
-
Bahar, R., et al. Increased cell-to-cell variation in gene expression in ageing mouse heart. Nature 441 (2006), 1011–1014.
-
(2006)
Nature
, vol.441
, pp. 1011-1014
-
-
Bahar, R.1
-
16
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack, A.S., et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317 (2007), 807–810.
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
-
17
-
-
77954950116
-
Progeria syndromes and ageing: what is the connection? Nature reviews
-
Burtner, C.R., Kennedy, B.K., Progeria syndromes and ageing: what is the connection? Nature reviews. Mol. Cell. Biol. 11 (2010), 567–578.
-
(2010)
Mol. Cell. Biol.
, vol.11
, pp. 567-578
-
-
Burtner, C.R.1
Kennedy, B.K.2
-
18
-
-
84934444350
-
Selecting a mouse model of Alzheimer׳s disease
-
Chin, J., Selecting a mouse model of Alzheimer׳s disease. Methods Mol. Biol. 670 (2011), 169–189.
-
(2011)
Methods Mol. Biol.
, vol.670
, pp. 169-189
-
-
Chin, J.1
-
19
-
-
84863671840
-
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors
-
Chambers, S.M., et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nat. Biotechnol. 30 (2012), 715–720.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 715-720
-
-
Chambers, S.M.1
-
20
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
Chambers, S.M., et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27 (2009), 275–280.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
-
21
-
-
84890547494
-
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
-
Chung, W.S., et al. Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways. Nature 504 (2013), 394–400.
-
(2013)
Nature
, vol.504
, pp. 394-400
-
-
Chung, W.S.1
-
22
-
-
84876668625
-
Emerging roles of astrocytes in neural circuit development
-
Clarke, L.E., Barres, B.A., Emerging roles of astrocytes in neural circuit development. Nat. Rev. Neurosci. 14 (2013), 311–321.
-
(2013)
Nat. Rev. Neurosci.
, vol.14
, pp. 311-321
-
-
Clarke, L.E.1
Barres, B.A.2
-
23
-
-
84912064761
-
A three-dimensional human neural cell culture model of Alzheimer׳s disease
-
Choi, S.H., et al. A three-dimensional human neural cell culture model of Alzheimer׳s disease. Nature 515 (2014), 274–278.
-
(2014)
Nature
, vol.515
, pp. 274-278
-
-
Choi, S.H.1
-
24
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson׳s disease
-
Cooper, O., et al. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson׳s disease. Sci. Trans. Med., 4, 2012, 141ra190.
-
(2012)
Sci. Trans. Med.
, vol.4
, pp. 141ra190
-
-
Cooper, O.1
-
25
-
-
84863230167
-
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington׳s disease patients demonstrates mutation related enhanced lysosomal activity
-
Camnasio, S., et al. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington׳s disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiol. Dis. 46 (2012), 41–51.
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 41-51
-
-
Camnasio, S.1
-
26
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy, I.M., et al. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433 (2005), 760–764.
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
-
27
-
-
84894248678
-
Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter
-
Chen, H., et al. Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter. Nucleic Acids Res. 42 (2014), 1563–1574.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 1563-1574
-
-
Chen, H.1
-
28
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
Caiazzo, M., et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 476 (2011), 224–227.
-
(2011)
Nature
, vol.476
, pp. 224-227
-
-
Caiazzo, M.1
-
29
-
-
77951978315
-
A defined long-term in vitro tissue engineered model of neuromuscular junctions
-
Das, M., Rumsey, J.W., Bhargava, N., Stancescu, M., Hickman, J.J., A defined long-term in vitro tissue engineered model of neuromuscular junctions. Biomaterials 31 (2010), 4880–4888.
-
(2010)
Biomaterials
, vol.31
, pp. 4880-4888
-
-
Das, M.1
Rumsey, J.W.2
Bhargava, N.3
Stancescu, M.4
Hickman, J.J.5
-
30
-
-
80052419902
-
Parkinson׳s disease induced pluripotent stem cells with triplication of the alpha-synuclein locus
-
Devine, M.J., et al. Parkinson׳s disease induced pluripotent stem cells with triplication of the alpha-synuclein locus. Nat. Commun., 2, 2011, 440.
-
(2011)
Nat. Commun.
, vol.2
, pp. 440
-
-
Devine, M.J.1
-
31
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos, J.T., et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321 (2008), 1218–1221.
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
-
32
-
-
84885808774
-
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
-
Donnelly, C.J., et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron 80 (2013), 415–428.
-
(2013)
Neuron
, vol.80
, pp. 415-428
-
-
Donnelly, C.J.1
-
33
-
-
41649097238
-
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
-
Dechat, T., et al. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes. Dev. 22 (2008), 832–853.
-
(2008)
Genes. Dev.
, vol.22
, pp. 832-853
-
-
Dechat, T.1
-
34
-
-
63549135460
-
Meta-analysis of age-related gene expression profiles identifies common signatures of aging
-
de Magalhaes, J.P., Curado, J., Church, G.M., Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics 25 (2009), 875–881.
-
(2009)
Bioinformatics
, vol.25
, pp. 875-881
-
-
de Magalhaes, J.P.1
Curado, J.2
Church, G.M.3
-
35
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert, A.D., et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457 (2009), 277–280.
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
-
36
-
-
84878878364
-
Integrating human pluripotent stem cells into drug development
-
Engle, S.J., Puppala, D., Integrating human pluripotent stem cells into drug development. Cell Stem Cell 12 (2013), 669–677.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 669-677
-
-
Engle, S.J.1
Puppala, D.2
-
37
-
-
54949102049
-
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals
-
Eiraku, M., et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 3 (2008), 519–532.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 519-532
-
-
Eiraku, M.1
-
38
-
-
79953749322
-
Self-organizing optic-cup morphogenesis in three-dimensional culture
-
Eiraku, M., et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472 (2011), 51–56.
-
(2011)
Nature
, vol.472
, pp. 51-56
-
-
Eiraku, M.1
-
39
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden, A., Gaudet, F., Waghmare, A., Jaenisch, R., Chromosomal instability and tumors promoted by DNA hypomethylation. Science, 300, 2003, 455.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
40
-
-
34547792388
-
Epigenetic gene silencing in cancer: the DNA hypermethylome
-
16 Spec No 1
-
Esteller, M., Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum. Mol. Genet., 2007, R50–R59 16 Spec No 1.
-
(2007)
Hum. Mol. Genet.
, pp. R50-R59
-
-
Esteller, M.1
-
41
-
-
0037673950
-
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
-
Eriksson, M., et al. Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 423 (2003), 293–298.
-
(2003)
Nature
, vol.423
, pp. 293-298
-
-
Eriksson, M.1
-
42
-
-
84876063744
-
A new definition of aging?
-
Flatt, T., A new definition of aging?. Front. Genet., 3, 2012, 148.
-
(2012)
Front. Genet.
, vol.3
, pp. 148
-
-
Flatt, T.1
-
44
-
-
84914113138
-
Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells
-
Frobel, J., et al. Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells. Stem Cell Rep. 3 (2014), 414–422.
-
(2014)
Stem Cell Rep.
, vol.3
, pp. 414-422
-
-
Frobel, J.1
-
45
-
-
34447625911
-
Epigenetics and aging: the targets and the marks
-
Fraga, M.F., Esteller, M., Epigenetics and aging: the targets and the marks. Trends Genet.: TIG 23 (2007), 413–418.
-
(2007)
Trends Genet.: TIG
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
46
-
-
79959836522
-
Chromatin structure as a mediator of aging
-
Feser, J., Tyler, J., Chromatin structure as a mediator of aging. FEBS Lett. 585 (2011), 2041–2048.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2041-2048
-
-
Feser, J.1
Tyler, J.2
-
47
-
-
84899644210
-
Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture
-
Gieseck, R.L. 3rd, et al. Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PLoS. One, 9, 2014, e86372.
-
(2014)
PLoS. One
, vol.9
, pp. e86372
-
-
Gieseck, R.L.1
-
48
-
-
80054067251
-
Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system
-
Guo, X., Gonzalez, M., Stancescu, M., Vandenburgh, H.H., Hickman, J.J., Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system. Biomaterials 32 (2011), 9602–9611.
-
(2011)
Biomaterials
, vol.32
, pp. 9602-9611
-
-
Guo, X.1
Gonzalez, M.2
Stancescu, M.3
Vandenburgh, H.H.4
Hickman, J.J.5
-
49
-
-
84872610509
-
BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function
-
Griep, L.M., et al. BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function. Biomed. Microdevices 15 (2013), 145–150.
-
(2013)
Biomed. Microdevices
, vol.15
, pp. 145-150
-
-
Griep, L.M.1
-
50
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet, F., et al. Induction of tumors in mice by genomic hypomethylation. Science 300 (2003), 489–492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
-
51
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath, S., DNA methylation age of human tissues and cell types. Genome Biol., 14, 2013, R115.
-
(2013)
Genome Biol.
, vol.14
, pp. R115
-
-
Horvath, S.1
-
52
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu, B.Y., et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 4335–4340.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
-
53
-
-
0029964643
-
Role of neurotrophic factors in neuronal development
-
Henderson, C.E., Role of neurotrophic factors in neuronal development. Curr. Opin. Neurobiol. 6 (1996), 64–70.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 64-70
-
-
Henderson, C.E.1
-
54
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer׳s amyloid beta-peptide
-
Haass, C., Selkoe, D.J., Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer׳s amyloid beta-peptide. Nat. Rev. Mol. Cell. Biol. 8 (2007), 101–112.
-
(2007)
Nat. Rev. Mol. Cell. Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
55
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
Heyn, H., et al. Distinct DNA methylomes of newborns and centenarians. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 10522–10527.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 10522-10527
-
-
Heyn, H.1
-
56
-
-
80052803450
-
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
-
Harries, L.W., et al. Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing. Aging Cell 10 (2011), 868–878.
-
(2011)
Aging Cell
, vol.10
, pp. 868-878
-
-
Harries, L.W.1
-
57
-
-
84856956771
-
Probing sporadic and familial Alzheimer׳s disease using induced pluripotent stem cells
-
Israel, M.A., et al. Probing sporadic and familial Alzheimer׳s disease using induced pluripotent stem cells. Nature 482 (2012), 216–220.
-
(2012)
Nature
, vol.482
, pp. 216-220
-
-
Israel, M.A.1
-
58
-
-
84867031150
-
Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
-
Imaizumi, Y., et al. Mitochondrial dysfunction associated with increased oxidative stress and alpha-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol. Brain, 5, 2012, 35.
-
(2012)
Mol. Brain
, vol.5
, pp. 35
-
-
Imaizumi, Y.1
-
59
-
-
84861203696
-
Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington׳s disease patient cells
-
Juopperi, T.A., et al. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington׳s disease patient cells. Mol. Brain, 5, 2012, 17.
-
(2012)
Mol. Brain
, vol.5
, pp. 17
-
-
Juopperi, T.A.1
-
60
-
-
84868008258
-
The role of DNA methylation in aging, rejuvenation, and age-related disease
-
Johnson, A.A., et al. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15 (2012), 483–494.
-
(2012)
Rejuvenation Res.
, vol.15
, pp. 483-494
-
-
Johnson, A.A.1
-
61
-
-
84875916922
-
Modeling Alzheimer׳s disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness
-
Kondo, T., et al. Modeling Alzheimer׳s disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness. Cell Stem Cell 12 (2013), 487–496.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 487-496
-
-
Kondo, T.1
-
62
-
-
0028841640
-
In vitro differentiation of embryonic stem cells
-
Keller, G.M., In vitro differentiation of embryonic stem cells. Curr. Opin. Cell. Biol. 7 (1995), 862–869.
-
(1995)
Curr. Opin. Cell. Biol.
, vol.7
, pp. 862-869
-
-
Keller, G.M.1
-
63
-
-
18844396119
-
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
-
Keller, G., Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes. Dev. 19 (2005), 1129–1155.
-
(2005)
Genes. Dev.
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
64
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson׳s disease
-
Kriks, S., et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson׳s disease. Nature 480 (2011), 547–551.
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
-
65
-
-
84876888499
-
The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening
-
Khan, J.M., Lyon, A.R., Harding, S.E., The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening. Br. J. Pharmacol. 169 (2013), 304–317.
-
(2013)
Br. J. Pharmacol.
, vol.169
, pp. 304-317
-
-
Khan, J.M.1
Lyon, A.R.2
Harding, S.E.3
-
66
-
-
84890282623
-
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
-
Kadoshima, T., et al. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 20284–20289.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 20284-20289
-
-
Kadoshima, T.1
-
67
-
-
78651427807
-
Micropatterning neural cell cultures in 3D with a multi-layered scaffold
-
Kunze, A., Giugliano, M., Valero, A., Renaud, P., Micropatterning neural cell cultures in 3D with a multi-layered scaffold. Biomaterials 32 (2011), 2088–2098.
-
(2011)
Biomaterials
, vol.32
, pp. 2088-2098
-
-
Kunze, A.1
Giugliano, M.2
Valero, A.3
Renaud, P.4
-
68
-
-
80053311182
-
On the programmed/non-programmed nature of ageing within the life history
-
Kirkwood, T.B., Melov, S., On the programmed/non-programmed nature of ageing within the life history. Curr. Biol.: CB 21 (2011), R701–R707.
-
(2011)
Curr. Biol.: CB
, vol.21
, pp. R701-R707
-
-
Kirkwood, T.B.1
Melov, S.2
-
69
-
-
77950200010
-
The genetics of ageing
-
Kenyon, C.J., The genetics of ageing. Nature 464 (2010), 504–512.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
70
-
-
38949104188
-
The coming acceleration of global population ageing
-
Lutz, W., Sanderson, W., Scherbov, S., The coming acceleration of global population ageing. Nature 451 (2008), 716–719.
-
(2008)
Nature
, vol.451
, pp. 716-719
-
-
Lutz, W.1
Sanderson, W.2
Scherbov, S.3
-
71
-
-
84870292016
-
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
-
Lafaille, F.G., et al. Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature 491 (2012), 769–773.
-
(2012)
Nature
, vol.491
, pp. 769-773
-
-
Lafaille, F.G.1
-
72
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
Lee, G., et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461 (2009), 402–406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
-
73
-
-
84870895081
-
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression
-
Lee, G., et al. Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nat. Biotechnol. 30 (2012), 1244–1248.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 1244-1248
-
-
Lee, G.1
-
74
-
-
84871936169
-
iPSC technology to study human aging and aging-related disorders
-
Liu, G.H., Ding, Z., Izpisua Belmonte, J.C., iPSC technology to study human aging and aging-related disorders. Curr. Opin. Cell. Biol. 24 (2012), 765–774.
-
(2012)
Curr. Opin. Cell. Biol.
, vol.24
, pp. 765-774
-
-
Liu, G.H.1
Ding, Z.2
Izpisua Belmonte, J.C.3
-
75
-
-
80455144472
-
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
-
Lapasset, L., et al. Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes. Dev. 25 (2011), 2248–2253.
-
(2011)
Genes. Dev.
, vol.25
, pp. 2248-2253
-
-
Lapasset, L.1
-
76
-
-
84891724275
-
Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells
-
Le, R., et al. Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells. Cell Stem Cell 14 (2014), 27–39.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 27-39
-
-
Le, R.1
-
77
-
-
0034104240
-
Nerve growth factor collaborates with myocyte-derived factors to promote development of presynaptic sites in cultured sympathetic neurons
-
Lockhart, S.T., Mead, J.N., Pisano, J.M., Slonimsky, J.D., Birren, S.J., Nerve growth factor collaborates with myocyte-derived factors to promote development of presynaptic sites in cultured sympathetic neurons. J. Neurobiol. 42 (2000), 460–476.
-
(2000)
J. Neurobiol.
, vol.42
, pp. 460-476
-
-
Lockhart, S.T.1
Mead, J.N.2
Pisano, J.M.3
Slonimsky, J.D.4
Birren, S.J.5
-
78
-
-
84884414984
-
Cerebral organoids model human brain development and microcephaly
-
Lancaster, M.A., et al. Cerebral organoids model human brain development and microcephaly. Nature 501 (2013), 373–379.
-
(2013)
Nature
, vol.501
, pp. 373-379
-
-
Lancaster, M.A.1
-
79
-
-
63149090431
-
Parkinson׳s disease: from monogenic forms to genetic susceptibility factors
-
Lesage, S., Brice, A., Parkinson׳s disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet. 18 (2009), R48–R59.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. R48-R59
-
-
Lesage, S.1
Brice, A.2
-
80
-
-
84869877601
-
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
-
Liu, G.H., et al. Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 491 (2012), 603–607.
-
(2012)
Nature
, vol.491
, pp. 603-607
-
-
Liu, G.H.1
-
81
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin, M.T., Beal, M.F., Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443 (2006), 787–795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
82
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M.A., Partridge, L., Serrano, M., Kroemer, G., The hallmarks of aging. Cell 153 (2013), 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
83
-
-
84864040434
-
Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging
-
Lee, J.S., et al. Meta-analysis of gene expression in the mouse liver reveals biomarkers associated with inflammation increased early during aging. Mech. Ageing Dev. 133 (2012), 467–478.
-
(2012)
Mech. Ageing Dev.
, vol.133
, pp. 467-478
-
-
Lee, J.S.1
-
84
-
-
84877687210
-
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy
-
Loffredo, F.S., et al. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell 153 (2013), 828–839.
-
(2013)
Cell
, vol.153
, pp. 828-839
-
-
Loffredo, F.S.1
-
85
-
-
84876959225
-
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs
-
Mica, Y., Lee, G., Chambers, S.M., Tomishima, M.J., Studer, L., Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell Rep. 3 (2013), 1140–1152.
-
(2013)
Cell Rep.
, vol.3
, pp. 1140-1152
-
-
Mica, Y.1
Lee, G.2
Chambers, S.M.3
Tomishima, M.J.4
Studer, L.5
-
86
-
-
84890109489
-
Human iPSC-based modeling of late-onset disease via progerin-induced aging
-
Miller, J.D., et al. Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell 13 (2013), 691–705.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 691-705
-
-
Miller, J.D.1
-
87
-
-
84871939334
-
Aging and reprogramming: a two-way street
-
Mahmoudi, S., Brunet, A., Aging and reprogramming: a two-way street. Curr. Opin. Cell. Biol. 24 (2012), 744–756.
-
(2012)
Curr. Opin. Cell. Biol.
, vol.24
, pp. 744-756
-
-
Mahmoudi, S.1
Brunet, A.2
-
88
-
-
58949094552
-
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells
-
Marion, R.M., et al. Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. Cell Stem Cell 4 (2009), 141–154.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 141-154
-
-
Marion, R.M.1
-
89
-
-
84877271854
-
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells
-
Maroof, A.M., et al. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 12 (2013), 559–572.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 559-572
-
-
Maroof, A.M.1
-
90
-
-
84918561297
-
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
-
McCracken, K.W., et al. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516 (2014), 400–404.
-
(2014)
Nature
, vol.516
, pp. 400-404
-
-
McCracken, K.W.1
-
91
-
-
84902303124
-
The familial Alzheimer׳s disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
-
Muratore, C.R., et al. The familial Alzheimer׳s disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons. Hum. Mol. Genet. 23 (2014), 3523–3536.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 3523-3536
-
-
Muratore, C.R.1
-
92
-
-
80052225992
-
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
-
Mitne-Neto, M., et al. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum. Mol. Genet. 20 (2011), 3642–3652.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 3642-3652
-
-
Mitne-Neto, M.1
-
93
-
-
84926674860
-
DNA methylation age of blood predicts all-cause mortality in later life
-
Marioni, R.E., et al. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol., 16, 2015, 25.
-
(2015)
Genome Biol.
, vol.16
, pp. 25
-
-
Marioni, R.E.1
-
94
-
-
84868194710
-
Astrocytes conspire with neurons during progression of neurological disease
-
McGann, J.C., Lioy, D.T., Mandel, G., Astrocytes conspire with neurons during progression of neurological disease. Curr. Opin. Neurobiol. 22 (2012), 850–858.
-
(2012)
Curr. Opin. Neurobiol.
, vol.22
, pp. 850-858
-
-
McGann, J.C.1
Lioy, D.T.2
Mandel, G.3
-
95
-
-
84872008549
-
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation
-
Nishimura, T., et al. Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell 12 (2013), 114–126.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 114-126
-
-
Nishimura, T.1
-
96
-
-
84877301288
-
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development
-
Nicholas, C.R., et al. Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell 12 (2013), 573–586.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 573-586
-
-
Nicholas, C.R.1
-
97
-
-
84862526635
-
Self-formation of optic cups and storable stratified neural retina from human ESCs
-
Nakano, T., et al. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 10 (2012), 771–785.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 771-785
-
-
Nakano, T.1
-
98
-
-
79952172335
-
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
-
Nguyen, H.N., et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8 (2011), 267–280.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 267-280
-
-
Nguyen, H.N.1
-
99
-
-
84864317150
-
Unique preservation of neural cells in Hutchinson–Gilford progeria syndrome is due to the expression of the neural-specific miR-9 microRNA
-
Nissan, X., et al. Unique preservation of neural cells in Hutchinson–Gilford progeria syndrome is due to the expression of the neural-specific miR-9 microRNA. Cell Rep. 2 (2012), 1–9.
-
(2012)
Cell Rep.
, vol.2
, pp. 1-9
-
-
Nissan, X.1
-
100
-
-
84867736667
-
Nuclear lamina defects cause ATM-dependent NF-kappaB activation and link accelerated aging to a systemic inflammatory response
-
Osorio, F.G., et al. Nuclear lamina defects cause ATM-dependent NF-kappaB activation and link accelerated aging to a systemic inflammatory response. Genes. Dev. 26 (2012), 2311–2324.
-
(2012)
Genes. Dev.
, vol.26
, pp. 2311-2324
-
-
Osorio, F.G.1
-
101
-
-
84855484998
-
Defining the nature of human pluripotent stem cell progeny
-
Patterson, M., et al. Defining the nature of human pluripotent stem cell progeny. Cell. Res. 22 (2012), 178–193.
-
(2012)
Cell. Res.
, vol.22
, pp. 178-193
-
-
Patterson, M.1
-
102
-
-
84910673362
-
Generation of functional human pancreatic beta cells in vitro
-
Pagliuca, F.W., et al. Generation of functional human pancreatic beta cells in vitro. Cell 159 (2014), 428–439.
-
(2014)
Cell
, vol.159
, pp. 428-439
-
-
Pagliuca, F.W.1
-
103
-
-
77951002352
-
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
-
Prigione, A., Fauler, B., Lurz, R., Lehrach, H., Adjaye, J., The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells 28 (2010), 721–733.
-
(2010)
Stem Cells
, vol.28
, pp. 721-733
-
-
Prigione, A.1
Fauler, B.2
Lurz, R.3
Lehrach, H.4
Adjaye, J.5
-
104
-
-
0030773837
-
Synaptic efficacy enhanced by glial cells in vitro
-
Pfrieger, F.W., Barres, B.A., Synaptic efficacy enhanced by glial cells in vitro. Science 277 (1997), 1684–1687.
-
(1997)
Science
, vol.277
, pp. 1684-1687
-
-
Pfrieger, F.W.1
Barres, B.A.2
-
105
-
-
10544234193
-
Mapping of a gene for Parkinson׳s disease to chromosome 4q21–q23
-
Polymeropoulos, M.H., et al. Mapping of a gene for Parkinson׳s disease to chromosome 4q21–q23. Science 274 (1996), 1197–1199.
-
(1996)
Science
, vol.274
, pp. 1197-1199
-
-
Polymeropoulos, M.H.1
-
106
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
Pfisterer, U., et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 10343–10348.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 10343-10348
-
-
Pfisterer, U.1
-
107
-
-
84983134468
-
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
-
Rezania, A., et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat. Biotechnol. 32 (2014), 1121–1133.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1121-1133
-
-
Rezania, A.1
-
108
-
-
84875140407
-
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression
-
Reinhardt, P., et al. Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression. Cell Stem Cell 12 (2013), 354–367.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 354-367
-
-
Reinhardt, P.1
-
109
-
-
84856090875
-
Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock
-
Rando, T.A., Chang, H.Y., Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell 148 (2012), 46–57.
-
(2012)
Cell
, vol.148
, pp. 46-57
-
-
Rando, T.A.1
Chang, H.Y.2
-
110
-
-
84860561774
-
Epigenetic reprogramming of cancer cells via targeted DNA methylation
-
Rivenbark, A.G., et al. Epigenetic reprogramming of cancer cells via targeted DNA methylation. Epigenetics: Off. J. DNA Methylation Soc. 7 (2012), 350–360.
-
(2012)
Epigenetics: Off. J. DNA Methylation Soc.
, vol.7
, pp. 350-360
-
-
Rivenbark, A.G.1
-
111
-
-
79955786943
-
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
-
Seibler, P., et al. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J. Neurosci.: Off. J. Soc. Neurosci. 31 (2011), 5970–5976.
-
(2011)
J. Neurosci.: Off. J. Soc. Neurosci.
, vol.31
, pp. 5970-5976
-
-
Seibler, P.1
-
112
-
-
77449124088
-
Telomere dynamics in human cells reprogrammed to pluripotency
-
Suhr, S.T., et al. Telomere dynamics in human cells reprogrammed to pluripotency. PLoS One, 4, 2009, e8124.
-
(2009)
PLoS One
, vol.4
, pp. e8124
-
-
Suhr, S.T.1
-
113
-
-
79952209101
-
Mitochondrial rejuvenation after induced pluripotency
-
Suhr, S.T., et al. Mitochondrial rejuvenation after induced pluripotency. PLoS One, 5, 2010, e14095.
-
(2010)
PLoS One
, vol.5
, pp. e14095
-
-
Suhr, S.T.1
-
114
-
-
84862778046
-
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
-
Shi, Y., Kirwan, P., Smith, J., Robinson, H.P., Livesey, F.J., Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat. Neurosci. 15:S471 (2012), S477–S486.
-
(2012)
Nat. Neurosci.
, vol.15
, Issue.S471
, pp. S477-S486
-
-
Shi, Y.1
Kirwan, P.2
Smith, J.3
Robinson, H.P.4
Livesey, F.J.5
-
115
-
-
84901414493
-
Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells
-
Srikanth, P., Young-Pearse, T.L., Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells. J. Neurogenetics 28 (2014), 5–29.
-
(2014)
J. Neurogenetics
, vol.28
, pp. 5-29
-
-
Srikanth, P.1
Young-Pearse, T.L.2
-
116
-
-
61349100729
-
Parkinson׳s disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner, F., et al. Parkinson׳s disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136 (2009), 964–977.
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
-
117
-
-
79960833952
-
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
-
Soldner, F., et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 146 (2011), 318–331.
-
(2011)
Cell
, vol.146
, pp. 318-331
-
-
Soldner, F.1
-
118
-
-
84860510280
-
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson׳s disease
-
Sanchez-Danes, A., et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson׳s disease. EMBO Mol. Med. 4 (2012), 380–395.
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 380-395
-
-
Sanchez-Danes, A.1
-
119
-
-
84887004639
-
Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
-
Su, Y.C., Qi, X., Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Hum. Mol. Genet. 22 (2013), 4545–4561.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 4545-4561
-
-
Su, Y.C.1
Qi, X.2
-
120
-
-
84887506882
-
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson׳s disease patients: reversal by gene correction
-
Sanders, L.H., et al. LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson׳s disease patients: reversal by gene correction. Neurobiol. Dis. 62 (2014), 381–386.
-
(2014)
Neurobiol. Dis.
, vol.62
, pp. 381-386
-
-
Sanders, L.H.1
-
121
-
-
84897136184
-
Characterization and molecular profiling of PSEN1 familial Alzheimer׳s disease iPSC-derived neural progenitors
-
Sproul, A.A., et al. Characterization and molecular profiling of PSEN1 familial Alzheimer׳s disease iPSC-derived neural progenitors. PLoS One, 9, 2014, e84547.
-
(2014)
PLoS One
, vol.9
, pp. e84547
-
-
Sproul, A.A.1
-
122
-
-
84886389563
-
Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion
-
Sareen, D., et al. Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion. Sci. Trans. Med., 5, 2013, 208ra149.
-
(2013)
Sci. Trans. Med.
, vol.5
, pp. 208ra149
-
-
Sareen, D.1
-
123
-
-
84879403017
-
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells
-
Tang, X., et al. Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Stem Cell Res. 11 (2013), 743–757.
-
(2013)
Stem Cell Res.
, vol.11
, pp. 743-757
-
-
Tang, X.1
-
124
-
-
84881184980
-
Vascularized and functional human liver from an iPSC-derived organ bud transplant
-
Takebe, T., et al. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 499 (2013), 481–484.
-
(2013)
Nature
, vol.499
, pp. 481-484
-
-
Takebe, T.1
-
125
-
-
84864019015
-
Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs
-
Talens, R.P., et al. Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell 11 (2012), 694–703.
-
(2012)
Aging Cell
, vol.11
, pp. 694-703
-
-
Talens, R.P.1
-
126
-
-
79960045188
-
Induced pluripotent stem cells for modelling human diseases. Philosophical transactions of the Royal Society of London
-
Unternaehrer, J.J., Daley, G.Q., Induced pluripotent stem cells for modelling human diseases. Philosophical transactions of the Royal Society of London. Ser. B Biol. Sci. 366 (2011), 2274–2285.
-
(2011)
Ser. B Biol. Sci.
, vol.366
, pp. 2274-2285
-
-
Unternaehrer, J.J.1
Daley, G.Q.2
-
127
-
-
0035951508
-
Control of synapse number by glia
-
Ullian, E.M., Sapperstein, S.K., Christopherson, K.S., Barres, B.A., Control of synapse number by glia. Science 291 (2001), 657–661.
-
(2001)
Science
, vol.291
, pp. 657-661
-
-
Ullian, E.M.1
Sapperstein, S.K.2
Christopherson, K.S.3
Barres, B.A.4
-
129
-
-
84902075251
-
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
-
Villeda, S.A., et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat. Med. 20 (2014), 659–663.
-
(2014)
Nat. Med.
, vol.20
, pp. 659-663
-
-
Villeda, S.A.1
-
130
-
-
80052410357
-
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
-
Villeda, S.A., et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477 (2011), 90–94.
-
(2011)
Nature
, vol.477
, pp. 90-94
-
-
Villeda, S.A.1
-
131
-
-
84912058317
-
iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson׳s disease
-
Woodard, C.M., et al. iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson׳s disease. Cell. Rep. 9 (2014), 1173–1182.
-
(2014)
Cell. Rep.
, vol.9
, pp. 1173-1182
-
-
Woodard, C.M.1
-
132
-
-
84896718645
-
Aging of blood can be tracked by DNA methylation changes at just three CpG sites
-
Weidner, C.I., et al. Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol., 15, 2014, R24.
-
(2014)
Genome Biol.
, vol.15
, pp. R24
-
-
Weidner, C.I.1
-
133
-
-
81255169342
-
Modeling familial Alzheimer׳s disease with induced pluripotent stem cells
-
Yagi, T., et al. Modeling familial Alzheimer׳s disease with induced pluripotent stem cells. Hum. Mol. Genet. 20 (2011), 4530–4539.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4530-4539
-
-
Yagi, T.1
-
134
-
-
84933677989
-
Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs
-
Yoshida, M., et al. Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs. Stem Cell Rep. 4 (2015), 561–568.
-
(2015)
Stem Cell Rep.
, vol.4
, pp. 561-568
-
-
Yoshida, M.1
-
135
-
-
0037015228
-
Stem cell-derived cardiomyocytes demonstrate arrhythmic potential
-
Zhang, Y.M., Hartzell, C., Narlow, M., Dudley, S.C. Jr., Stem cell-derived cardiomyocytes demonstrate arrhythmic potential. Circulation 106 (2002), 1294–1299.
-
(2002)
Circulation
, vol.106
, pp. 1294-1299
-
-
Zhang, Y.M.1
Hartzell, C.2
Narlow, M.3
Dudley, S.C.4
-
136
-
-
84878849645
-
Rapid single-step induction of functional neurons from human pluripotent stem cells
-
Zhang, Y., et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 78 (2013), 785–798.
-
(2013)
Neuron
, vol.78
, pp. 785-798
-
-
Zhang, Y.1
-
137
-
-
84877734347
-
Hypothalamic programming of systemic ageing involving IKK-beta, NF-kappaB and GnRH
-
Zhang, G., et al. Hypothalamic programming of systemic ageing involving IKK-beta, NF-kappaB and GnRH. Nature 497 (2013), 211–216.
-
(2013)
Nature
, vol.497
, pp. 211-216
-
-
Zhang, G.1
|