Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

Nature

Volumn 491, Issue 7426, 2012, Pages 769-773

  Lafaille, Fabien G ^a   Pessach, Itai M ^b,c   Zhang, Shen Ying ^d,e   Ciancanelli, Michael J ^d   Herman, Melina ^d,e   Abhyankar, Avinash ^d   Ying, Shui Wang ^e   Keros, Sotirios ^f   Goldstein, Peter A ^f   Mostoslavsky, Gustavo ^g   Ordovas Montanes, Jose ^b   Jouanguy, Emmanuelle ^d,e   Plancoulaine, Sabine ^e   Tu, Edmund ^a   Elkabetz, Yechiel ^c   Al Muhsen, Saleh ^h   Tardieu, Marc ⁱ   Schlaeger, Thorsten M ^j   Daley, George Q ^j   Abel, Laurent ^d,e   Casanova, Jean Laurent ^d,e,k   Studer, Lorenz ^a   Notarangelo, Luigi D ^b   more..

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d ROCKEFELLER UNIVERSITY   (United States)

^e IMAGINE INSTITUTE   (France)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h KING SAUD UNIVERSITY   (Saudi Arabia)

ⁱ BICÊTRE HOSPITAL   (France)

^j DANA FARBER CANCER INSTITUTE   (United States)

^k HÔPITAL NECKER ENFANTS MALADES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; DOUBLE STRANDED RNA; INTERLEUKIN 29; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3;

CHILD HEALTH; CYTOLOGY; ENCEPHALITIS; HYPOTHESIS TESTING; IMMUNITY; NEUROLOGY; PATHOGEN; PATHOLOGY; PROTEIN; PUBLIC HEALTH; VIRAL DISEASE;

ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; NERVE CELL; NEURAL STEM CELL; OLIGODENDROGLIA; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SKIN FIBROBLAST; VIRUS IMMUNITY;

ASTROCYTES; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CHILD; DISEASE SUSCEPTIBILITY; ENCEPHALITIS, HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INDUCED PLURIPOTENT STEM CELLS; INTERFERONS; MEMBRANE TRANSPORT PROTEINS; NEURAL STEM CELLS; NEURONS; OLIGODENDROGLIA; TOLL-LIKE RECEPTOR 3;

HUMAN HERPESVIRUS 1;

EID: 84870292016     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11583     Document Type: Article

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