Human iPSC-based modeling of late-onset disease via progerin-induced aging

Cell Stem Cell

Volumn 13, Issue 6, 2013, Pages 691-705

  Miller, Justine D ^a   Ganat, Yosif M ^a   Kishinevsky, Sarah ^a   Bowman, Robert L ^a   Liu, Becky ^a   Tu, Edmund Y ^a   Mandal, Pankaj K ^b,c   Vera, Elsa ^a   Shim, Jae Won ^a   Kriks, Sonja ^a   Taldone, Tony ^a   Fusaki, Noemi ^d,e   Tomishima, Mark J ^a   Krainc, Dimitri ^f   Milner, Teresa A ^g,h   Rossi, Derrick J ^b,c   Studer, Lorenz ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Harvard University   (United States)

^d DNAVEC Corporation   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^h ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; LAMIN A; NEUROMELANIN; PROGERIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL AGING; CELL DIFFERENTIATION; CELL INCLUSION; CELL LINEAGE; CONTROLLED STUDY; DENDRITE; DENDRITE DEGENERATION; DISEASE ASSOCIATION; DISEASE MODEL; DONOR; DOPAMINERGIC NERVE CELL; FIBROBLAST; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEWY BODY; MITOCHONDRION SWELLING; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PHENOTYPE; PLURIPOTENT STEM CELL; PRECURSOR; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; AGING; ANIMALS; BIOLOGICAL MARKERS; CELL AGING; CELL DIFFERENTIATION; CHILD; DOPAMINERGIC NEURONS; FIBROBLASTS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MESENCEPHALON; MICE; MIDDLE AGED; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; NUCLEAR REPROGRAMMING; PARKINSON DISEASE; PHENOTYPE; PROTEIN PRECURSORS; TISSUE DONORS;

EID: 84890109489     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2013.11.006     Document Type: Article

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