-
2
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, et al. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 2012;8:e1002629.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002629
-
-
Bell, J.T.1
Tsai, P.C.2
Yang, T.P.3
Pidsley, R.4
Nisbet, J.5
Glass, D.6
-
3
-
-
60849100524
-
Decline in genomic DNA methylation through aging in a cohort of elderly subjects
-
Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, et al. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mech Ageing Dev. 2009;130:234-9.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 234-239
-
-
Bollati, V.1
Schwartz, J.2
Wright, R.3
Litonjua, A.4
Tarantini, L.5
Suh, H.6
-
4
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 2009;5:e1000602.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000602
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
Zheng, S.4
Wrensch, M.R.5
Wiemels, J.L.6
-
5
-
-
34447625911
-
Epigenetics and aging: the targets and the marks
-
Fraga MF, Esteller M. Epigenetics and aging: the targets and the marks. Trends Genet. 2007;23:413-8.
-
(2007)
Trends Genet
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
6
-
-
79952202597
-
Epigenetic regulation of aging
-
Rodriguez-Rodero S, Fernandez-Morera JL, Fernandez AF, Menendez-Torre E, Fraga MF. Epigenetic regulation of aging. Discov Med. 2010;10:225-33.
-
(2010)
Discov Med
, vol.10
, pp. 225-233
-
-
Rodriguez-Rodero, S.1
Fernandez-Morera, J.L.2
Fernandez, A.F.3
Menendez-Torre, E.4
Fraga, M.F.5
-
7
-
-
77957333258
-
Induction of epigenetic alterations by dietary and other environmental factors
-
Mathers JC, Strathdee G, Relton CL. Induction of epigenetic alterations by dietary and other environmental factors. Adv Genetics. 2010;71:3-39.
-
(2010)
Adv Genetics
, vol.71
, pp. 3-39
-
-
Mathers, J.C.1
Strathdee, G.2
Relton, C.L.3
-
8
-
-
84867063994
-
DNA methylation studies using twins: what are they telling us?
-
Bell JT, Spector TD. DNA methylation studies using twins: what are they telling us? Genome Biol. 2012;13:172.
-
(2012)
Genome Biol
, vol.13
, pp. 172
-
-
Bell, J.T.1
Spector, T.D.2
-
9
-
-
84867133601
-
Genetic and epigenetic contribution to complex traits
-
Kilpinen H, Dermitzakis ET. Genetic and epigenetic contribution to complex traits. Hum Mol Genet. 2012;21:R24-8.
-
(2012)
Hum Mol Genet
, vol.21
, pp. R24-R28
-
-
Kilpinen, H.1
Dermitzakis, E.T.2
-
10
-
-
84872806231
-
Genome-wide methylation profiles reveal quantitative views of human aging rates
-
Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49:359-67.
-
(2013)
Mol Cell
, vol.49
, pp. 359-367
-
-
Hannum, G.1
Guinney, J.2
Zhao, L.3
Zhang, L.4
Hughes, G.5
Sadda, S.6
-
11
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14:R115.
-
(2013)
Genome Biol
, vol.14
, pp. R115
-
-
Horvath, S.1
-
12
-
-
84896718645
-
Aging of blood can be tracked by DNA methylation changes at just three CpG sites
-
Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, et al. Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol. 2014;15:R24.
-
(2014)
Genome Biol
, vol.15
, pp. R24
-
-
Weidner, C.I.1
Lin, Q.2
Koch, C.M.3
Eisele, L.4
Beier, F.5
Ziegler, P.6
-
14
-
-
38849151645
-
The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond
-
Deary IJ, Gow AJ, Taylor MD, Corley J, Brett C, Wilson V, et al. The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond. BMC Geriatr. 2007;7:28.
-
(2007)
BMC Geriatr
, vol.7
, pp. 28
-
-
Deary, I.J.1
Gow, A.J.2
Taylor, M.D.3
Corley, J.4
Brett, C.5
Wilson, V.6
-
15
-
-
1642455817
-
The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947
-
Deary IJ, Whiteman MC, Starr JM, Whalley LJ, Fox HC. The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947. J Pers Soc Psychol. 2004;86:130-47.
-
(2004)
J Pers Soc Psychol
, vol.86
, pp. 130-147
-
-
Deary, I.J.1
Whiteman, M.C.2
Starr, J.M.3
Whalley, L.J.4
Fox, H.C.5
-
17
-
-
0018612858
-
An investigation of coronary heart disease in families. The Framingham offspring study
-
Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epid. 1979;110:281-90.
-
(1979)
Am J Epid
, vol.110
, pp. 281-290
-
-
Kannel, W.B.1
Feinleib, M.2
McNamara, P.M.3
Garrison, R.J.4
Castelli, W.P.5
-
18
-
-
0013994140
-
The Veterans Administration longitudinal study of healthy aging
-
Bell B, Rose CL, Damon A. The Veterans Administration longitudinal study of healthy aging. The Gerontologist. 1966;6:179-84.
-
(1966)
The Gerontologist
, vol.6
, pp. 179-184
-
-
Bell, B.1
Rose, C.L.2
Damon, A.3
-
19
-
-
84939165580
-
The VA Normative Aging Study
-
Markides KS, editor. Thousand Oaks, CA: Sage
-
Spiro 3rd A, Vokonas P. The VA Normative Aging Study. In: Markides KS, editor. Encyclopedia of health and aging. Thousand Oaks, CA: Sage; 2007. p. 421-2.
-
(2007)
Encyclopedia of health and aging
, pp. 421-422
-
-
Spiro I.I.I, A.1
Vokonas, P.2
-
20
-
-
84860372128
-
The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics
-
Powell JE, Henders AK, McRae AF, Caracella A, Smith S, Wright MJ, et al. The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. PLoS One. 2012;7:e35430.
-
(2012)
PLoS One
, vol.7
, pp. e35430
-
-
Powell, J.E.1
Henders, A.K.2
McRae, A.F.3
Caracella, A.4
Smith, S.5
Wright, M.J.6
-
21
-
-
84860637797
-
DNA methylation arrays as surrogate measures of cell mixture distribution
-
Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics. 2012;13:86.
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 86
-
-
Houseman, E.A.1
Accomando, W.P.2
Koestler, D.C.3
Christensen, B.C.4
Marsit, C.J.5
Nelson, H.H.6
-
22
-
-
84893192328
-
Accounting for cellular heterogeneity is critical in epigenome-wide association studies
-
Jaffe AE, Irizarry RA. Accounting for cellular heterogeneity is critical in epigenome-wide association studies. Genome Biol. 2014;15:R31.
-
(2014)
Genome Biol
, vol.15
, pp. R31
-
-
Jaffe, A.E.1
Irizarry, R.A.2
-
23
-
-
42049114444
-
Aging of the immune system as a prognostic factor for human longevity
-
Larbi A, Franceschi C, Mazzatti D, Solana R, Wikby A, Pawelec G. Aging of the immune system as a prognostic factor for human longevity. Physiology (Bethesda). 2008;23:64-74.
-
(2008)
Physiology (Bethesda)
, vol.23
, pp. 64-74
-
-
Larbi, A.1
Franceschi, C.2
Mazzatti, D.3
Solana, R.4
Wikby, A.5
Pawelec, G.6
-
24
-
-
0034194058
-
Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging
-
Fagnoni FF, Vescovini R, Passeri G, Bologna G, Pedrazzoni M, Lavagetto G, et al. Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging. Blood. 2000;95:2860-8.
-
(2000)
Blood
, vol.95
, pp. 2860-2868
-
-
Fagnoni, F.F.1
Vescovini, R.2
Passeri, G.3
Bologna, G.4
Pedrazzoni, M.5
Lavagetto, G.6
-
25
-
-
84895463355
-
Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions
-
Biessels GJ, Strachan MW, Visseren FLJ, Kappelle LJ, Whitmer RA. Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions. Lancet Diabetes Endocrinol. 2014;2:246-55.
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 246-255
-
-
Biessels, G.J.1
Strachan, M.W.2
Visseren, F.L.J.3
Kappelle, L.J.4
Whitmer, R.A.5
-
26
-
-
22144451172
-
The age-dependent relation of blood pressure to cognitive function and dementia
-
Qiu C, Winblad B, Fratiglioni L. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol. 2005;4:487-99.
-
(2005)
Lancet Neurol
, vol.4
, pp. 487-499
-
-
Qiu, C.1
Winblad, B.2
Fratiglioni, L.3
-
28
-
-
79953239129
-
Intelligence and personality as predictors of illness and death: How researchers in differential psychology and chronic disease epidemiology are collaborating to understand and address health inequalities
-
Deary IJ, Weiss A, Batty GD. Intelligence and personality as predictors of illness and death: How researchers in differential psychology and chronic disease epidemiology are collaborating to understand and address health inequalities. Psychol Sci Publ Interest. 2010;11:53-79.
-
(2010)
Psychol Sci Publ Interest
, vol.11
, pp. 53-79
-
-
Deary, I.J.1
Weiss, A.2
Batty, G.D.3
-
29
-
-
0028359655
-
Genetic associations with human longevity at the APOE and ACE loci
-
Schächter F, Faure-Delanef L, Guénot F, Rouger H, Froguel P, Lesueur-Ginot L, et al. Genetic associations with human longevity at the APOE and ACE loci. Nat Genet. 1994;6:29-32.
-
(1994)
Nat Genet
, vol.6
, pp. 29-32
-
-
Schächter, F.1
Faure-Delanef, L.2
Guénot, F.3
Rouger, H.4
Froguel, P.5
Lesueur-Ginot, L.6
-
30
-
-
3042700097
-
Mortality in relation to smoking: 50 years' observations on male British doctors
-
Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ. 2004;328:1519.
-
(2004)
BMJ
, vol.328
, pp. 1519
-
-
Doll, R.1
Peto, R.2
Boreham, J.3
Sutherland, I.4
-
31
-
-
77953949784
-
Intelligence, education, and mortality
-
Batty GD, Kivimaki M, Deary IJ. Intelligence, education, and mortality. BMJ. 2010;340:c563.
-
(2010)
BMJ
, vol.340
, pp. c563
-
-
Batty, G.D.1
Kivimaki, M.2
Deary, I.J.3
-
32
-
-
79961188823
-
Intelligence in youth and all-cause-mortality: systematic review with meta-analysis
-
Calvin CM, Deary IJ, Fenton C, Roberts BA, Der G, Leckenby N, et al. Intelligence in youth and all-cause-mortality: systematic review with meta-analysis. Int J Epidemiol. 2011;40:626-44.
-
(2011)
Int J Epidemiol
, vol.40
, pp. 626-644
-
-
Calvin, C.M.1
Deary, I.J.2
Fenton, C.3
Roberts, B.A.4
Der, G.5
Leckenby, N.6
-
33
-
-
54949124245
-
Do conscientious individuals live longer? A quantitative review
-
Kern ML, Friedman HS. Do conscientious individuals live longer? A quantitative review. Health Psychol. 2008;27:505-12.
-
(2008)
Health Psychol
, vol.27
, pp. 505-512
-
-
Kern, M.L.1
Friedman, H.S.2
-
34
-
-
84896751305
-
Longitudinal changes in leukocyte telomere length and mortality in humans
-
Bendix L, Thinggaard M, Fenger M, Kolvraa S, Avlund K, Linneberg A, et al. Longitudinal changes in leukocyte telomere length and mortality in humans. J Gerontol A Biol Sci Med Sci. 2014;69:231-9.
-
(2014)
J Gerontol A Biol Sci Med Sci
, vol.69
, pp. 231-239
-
-
Bendix, L.1
Thinggaard, M.2
Fenger, M.3
Kolvraa, S.4
Avlund, K.5
Linneberg, A.6
-
35
-
-
0037308404
-
Association between telomere length in blood and mortality in people aged 60 years or older
-
Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet. 2003;361:393-5.
-
(2003)
Lancet
, vol.361
, pp. 393-395
-
-
Cawthon, R.M.1
Smith, K.R.2
O'Brien, E.3
Sivatchenko, A.4
Kerber, R.A.5
-
37
-
-
0041109533
-
-
London: University of London Press
-
Scottish Council for Research in Education. The Trend of Scottish Intelligence. London: University of London Press; 1949.
-
(1949)
The Trend of Scottish Intelligence
-
-
-
38
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM, et al. High density DNA methylation array with single CpG site resolution. Genomics. 2011;98:288-95.
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
Ho, V.4
Klotzle, B.5
Le, J.M.6
-
39
-
-
84897548625
-
Minfi: A flexible and comprehensive Bioconductor package for the analysis of Infinium DNA Methylation microarrays
-
Aryee MJ, Jaffe AE, Corrada-Bravo H, Ladd-Acosta C, Feinberg AP, Hansen KD, et al. Minfi: A flexible and comprehensive Bioconductor package for the analysis of Infinium DNA Methylation microarrays. Bioinformatics. 2014;30:1363-9.
-
(2014)
Bioinformatics
, vol.30
, pp. 1363-1369
-
-
Aryee, M.J.1
Jaffe, A.E.2
Corrada-Bravo, H.3
Ladd-Acosta, C.4
Feinberg, A.P.5
Hansen, K.D.6
-
41
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1215.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
42
-
-
0025801744
-
Apolipoprotein E genotyping by one-stage PCR
-
Wenham PR, Price WH, Blandell G. Apolipoprotein E genotyping by one-stage PCR. Lancet. 1991;337:1158-9.
-
(1991)
Lancet
, vol.337
, pp. 1158-1159
-
-
Wenham, P.R.1
Price, W.H.2
Blandell, G.3
-
45
-
-
77953300201
-
Differences in the haematological profile of healthy 70 year old men and women: normal ranges with confirmatory factor analysis
-
McIlhagger R, Gow AJ, Brett CE, Corley J, Taylor M, Deary IJ, et al. Differences in the haematological profile of healthy 70 year old men and women: normal ranges with confirmatory factor analysis. BMC Blood Disord. 2010;10:4.
-
(2010)
BMC Blood Disord
, vol.10
, pp. 4
-
-
McIlhagger, R.1
Gow, A.J.2
Brett, C.E.3
Corley, J.4
Taylor, M.5
Deary, I.J.6
-
46
-
-
84888266953
-
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells
-
Zhang Y, Maksimovic J, Naselli G, Qian J, Chopin M, Blewitt ME, et al. Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood. 2013;122:2823-36.
-
(2013)
Blood
, vol.122
, pp. 2823-2836
-
-
Zhang, Y.1
Maksimovic, J.2
Naselli, G.3
Qian, J.4
Chopin, M.5
Blewitt, M.E.6
-
47
-
-
80054821706
-
-
R package version 2.16. Accessed January 2014.
-
Schwarzer G. meta: Meta-Analysis with R. R package version 2.16. 2014. Accessed January 2014.
-
(2014)
meta: Meta-Analysis with R
-
-
Schwarzer, G.1
-
49
-
-
84864507889
-
A Package for Survival Analysis in S
-
R package version 2.37-7. Accessed January 2014.
-
Therneau TM. A Package for Survival Analysis in S. R package version 2.37-7. 2014. Accessed January 2014.
-
(2014)
-
-
Therneau, T.M.1
-
50
-
-
0033909546
-
A general test of association for quantitative traits in nuclear families
-
Abecasis GR, Cardon LR, Cookson WO. A general test of association for quantitative traits in nuclear families. Am J Hum Genet. 2000;66:279-92.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 279-292
-
-
Abecasis, G.R.1
Cardon, L.R.2
Cookson, W.O.3
|