Cerebral organoids model human brain development and microcephaly

Nature

Volumn 501, Issue 7467, 2013, Pages 373-379

  Lancaster, Madeline A ^a   Renner, Magdalena ^a   Martin, Carol Anne ^b   Wenzel, Daniel ^a   Bicknell, Louise S ^b   Hurles, Matthew E ^c   Homfray, Tessa ^d   Penninger, Josef M ^a   Jackson, Andrew P ^b   Knoblich, Juergen A ^a  

^a INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BRAIN; CELL ORGANELLE; COMPLEXITY; DATA SET; DISEASE; PHENOTYPE; RNA; STEM;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; BRAIN REGION; CEREBRAL ORGANOID; CYTOPLASM; HUMAN; IN VITRO STUDY; MICROCEPHALY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; BRAIN; CEREBRAL CORTEX; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICROCEPHALY; MODELS, BIOLOGICAL; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; ORGANOIDS; TISSUE CULTURE TECHNIQUES;

MUS;

EID: 84884414984     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12517     Document Type: Article

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