-
1
-
-
37249009271
-
Motif module map reveals enforcement of aging by continual NF-κB activity
-
DOI 10.1101/gad.1588507
-
A.S. Adler, S. Sinha, T.L. Kawahara, J.Y. Zhang, E. Segal, and H.Y. Chang Motif module map reveals enforcement of aging by continual NF-kappaB activity Genes Dev. 21 2007 3244 3257 (Pubitemid 350277752)
-
(2007)
Genes and Development
, vol.21
, Issue.24
, pp. 3244-3257
-
-
Adler, A.S.1
Sinha, S.2
Kawahara, T.L.A.3
Zhang, J.Y.4
Segal, E.5
Chang, H.Y.6
-
2
-
-
77949424341
-
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
-
S. Agarwal, Y.H. Loh, E.M. McLoughlin, J. Huang, I.H. Park, J.D. Miller, H. Huo, M. Okuka, R.M. Dos Reis, and S. Loewer Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients Nature 464 2010 292 296
-
(2010)
Nature
, vol.464
, pp. 292-296
-
-
Agarwal, S.1
Loh, Y.H.2
McLoughlin, E.M.3
Huang, J.4
Park, I.H.5
Miller, J.D.6
Huo, H.7
Okuka, M.8
Dos Reis, R.M.9
Loewer, S.10
-
3
-
-
66149138053
-
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
-
K. Agger, P.A. Cloos, L. Rudkjaer, K. Williams, G. Andersen, J. Christensen, and K. Helin The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence Genes Dev. 23 2009 1171 1176
-
(2009)
Genes Dev.
, vol.23
, pp. 1171-1176
-
-
Agger, K.1
Cloos, P.A.2
Rudkjaer, L.3
Williams, K.4
Andersen, G.5
Christensen, J.6
Helin, K.7
-
4
-
-
10644282295
-
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
-
DOI 10.1101/gad.1255404
-
J. Apfeld, G. O'Connor, T. McDonagh, P.S. DiStefano, and R. Curtis The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans Genes Dev. 18 2004 3004 3009 (Pubitemid 39658169)
-
(2004)
Genes and Development
, vol.18
, Issue.24
, pp. 3004-3009
-
-
Apfeld, J.1
O'Connor, G.2
McDonagh, T.3
DiStefano, P.S.4
Curtis, R.5
-
5
-
-
33745532801
-
Increased cell-to-cell variation in gene expression in ageing mouse heart
-
DOI 10.1038/nature04844, PII N04844
-
R. Bahar, C.H. Hartmann, K.A. Rodriguez, A.D. Denny, R.A. Busuttil, M.E. Dollé, R.B. Calder, G.B. Chisholm, B.H. Pollock, C.A. Klein, and J. Vijg Increased cell-to-cell variation in gene expression in ageing mouse heart Nature 441 2006 1011 1014 (Pubitemid 43980358)
-
(2006)
Nature
, vol.441
, Issue.7096
, pp. 1011-1014
-
-
Bahar, R.1
Hartmann, C.H.2
Rodriguez, K.A.3
Denny, A.D.4
Busuttil, R.A.5
Dolle, M.E.T.6
Calder, R.B.7
Chisholm, G.B.8
Pollock, B.H.9
Klein, C.A.10
Vijg, J.11
-
6
-
-
66149135288
-
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
-
M. Barradas, E. Anderton, J.C. Acosta, S. Li, A. Banito, M. Rodriguez-Niedenführ, G. Maertens, M. Banck, M.M. Zhou, and M.J. Walsh Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS Genes Dev. 23 2009 1177 1182
-
(2009)
Genes Dev.
, vol.23
, pp. 1177-1182
-
-
Barradas, M.1
Anderton, E.2
Acosta, J.C.3
Li, S.4
Banito, A.5
Rodriguez- Niedenführ, M.6
Maertens, G.7
Banck, M.8
Zhou, M.M.9
Walsh, M.J.10
-
7
-
-
79959282291
-
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
-
L.F. Batista, M.F. Pech, F.L. Zhong, H.N. Nguyen, K.T. Xie, A.J. Zaug, S.M. Crary, J. Choi, V. Sebastiano, and A. Cherry Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells Nature 474 2011 399 402
-
(2011)
Nature
, vol.474
, pp. 399-402
-
-
Batista, L.F.1
Pech, M.F.2
Zhong, F.L.3
Nguyen, H.N.4
Xie, K.T.5
Zaug, A.J.6
Crary, S.M.7
Choi, J.8
Sebastiano, V.9
Cherry, A.10
-
8
-
-
78049402859
-
Molecular signals of epigenetic states
-
R. Bonasio, S. Tu, and D. Reinberg Molecular signals of epigenetic states Science 330 2010 612 616
-
(2010)
Science
, vol.330
, pp. 612-616
-
-
Bonasio, R.1
Tu, S.2
Reinberg, D.3
-
9
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
DOI 10.1126/science.1144090
-
A.S. Brack, M.J. Conboy, S. Roy, M. Lee, C.J. Kuo, C. Keller, and T.A. Rando Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis Science 317 2007 807 810 (Pubitemid 47257918)
-
(2007)
Science
, vol.317
, Issue.5839
, pp. 807-810
-
-
Brack, A.S.1
Conboy, M.J.2
Roy, S.3
Lee, M.4
Kuo, C.J.5
Keller, C.6
Rando, T.A.7
-
10
-
-
0000042464
-
Transplantation of Living Nuclei from Blastula Cells into Enucleated Frogs' Eggs
-
R. Briggs, and T.J. King Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs Proc. Natl. Acad. Sci. USA 38 1952 455 463
-
(1952)
Proc. Natl. Acad. Sci. USA
, vol.38
, pp. 455-463
-
-
Briggs, R.1
King, T.J.2
-
11
-
-
84981012984
-
An improved method of parabiosis
-
E. Bunster, and R.K. Meyer An improved method of parabiosis Anat. Rec. 57 1933 339 343
-
(1933)
Anat. Rec.
, vol.57
, pp. 339-343
-
-
Bunster, E.1
Meyer, R.K.2
-
12
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
C. Burnett, S. Valentini, F. Cabreiro, M. Goss, M. Somogyvári, M.D. Piper, M. Hoddinott, G.L. Sutphin, V. Leko, and J.J. McElwee Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila Nature 477 2011 482 485
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvári, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
-
13
-
-
0029967424
-
Sheep cloned by nuclear transfer from a cultured cell line
-
DOI 10.1038/380064a0
-
K.H. Campbell, J. McWhir, W.A. Ritchie, and I. Wilmut Sheep cloned by nuclear transfer from a cultured cell line Nature 380 1996 64 66 (Pubitemid 26076237)
-
(1996)
Nature
, vol.380
, Issue.6569
, pp. 64-66
-
-
Campbell, K.H.S.1
McWhir, J.2
Ritchie, W.A.3
Wilmut, I.4
-
14
-
-
64949135819
-
Does damage to DNA and other macromolecules play a role in aging? if so, how?
-
J. Campisi, and J. Vijg Does damage to DNA and other macromolecules play a role in aging? If so, how? J. Gerontol. A Biol. Sci. Med. Sci. 64 2009 175 178
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 175-178
-
-
Campisi, J.1
Vijg, J.2
-
15
-
-
0028975575
-
Revival and identification of bacterial spores in 25- to 40-million-year-old Dominican amber
-
R.J. Cano, and M.K. Borucki Revival and identification of bacterial spores in 25- to 40-million-year-old Dominican amber Science 268 1995 1060 1064
-
(1995)
Science
, vol.268
, pp. 1060-1064
-
-
Cano, R.J.1
Borucki, M.K.2
-
16
-
-
47949097215
-
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
-
M.E. Carlson, M. Hsu, and I.M. Conboy Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells Nature 454 2008 528 532
-
(2008)
Nature
, vol.454
, pp. 528-532
-
-
Carlson, M.E.1
Hsu, M.2
Conboy, I.M.3
-
18
-
-
28844469898
-
Medicine: Increase in activity during calorie restriction requires Sirt1
-
DOI 10.1126/science.1118357
-
D. Chen, A.D. Steele, S. Lindquist, and L. Guarente Increase in activity during calorie restriction requires Sirt1 Science 310 2005 1641 (Pubitemid 41780779)
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
19
-
-
75549090275
-
MTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
-
C. Chen, Y. Liu, Y. Liu, and P. Zheng mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells Sci. Signal. 2 2009 ra75
-
(2009)
Sci. Signal.
, vol.2
, pp. 75
-
-
Chen, C.1
Liu, Y.2
Liu, Y.3
Zheng, P.4
-
20
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
DOI 10.1038/nature03260
-
I.M. Conboy, M.J. Conboy, A.J. Wagers, E.R. Girma, I.L. Weissman, and T.A. Rando Rejuvenation of aged progenitor cells by exposure to a young systemic environment Nature 433 2005 760 764 (Pubitemid 40292986)
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weismann, I.L.5
Rando, T.A.6
-
21
-
-
23944457397
-
Developmental Biology: Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
DOI 10.1126/science.1116447
-
C.A. Cowan, J. Atienza, D.A. Melton, and K. Eggan Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells Science 309 2005 1369 1373 (Pubitemid 41209363)
-
(2005)
Science
, vol.309
, Issue.5739
, pp. 1369-1373
-
-
Cowan, C.A.1
Atienza, J.2
Melton, D.A.3
Eggan, K.4
-
22
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
M.P. Creyghton, A.W. Cheng, G.G. Welstead, T. Kooistra, B.W. Carey, E.J. Steine, J. Hanna, M.A. Lodato, G.M. Frampton, and P.A. Sharp Histone H3K27ac separates active from poised enhancers and predicts developmental state Proc. Natl. Acad. Sci. USA 107 2010 21931 21936
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
Carey, B.W.5
Steine, E.J.6
Hanna, J.7
Lodato, M.A.8
Frampton, G.M.9
Sharp, P.A.10
-
23
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular lifespan
-
W. Dang, K.K. Steffen, R. Perry, J.A. Dorsey, F.B. Johnson, A. Shilatifard, M. Kaeberlein, B.K. Kennedy, and S.L. Berger Histone H4 lysine 16 acetylation regulates cellular lifespan Nature 459 2009 802 807
-
(2009)
Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
Dorsey, J.A.4
Johnson, F.B.5
Shilatifard, A.6
Kaeberlein, M.7
Kennedy, B.K.8
Berger, S.L.9
-
24
-
-
34548644772
-
The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing
-
DOI 10.1016/j.cell.2007.08.019, PII S0092867407010823
-
F. De Santa, M.G. Totaro, E. Prosperini, S. Notarbartolo, G. Testa, and G. Natoli The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing Cell 130 2007 1083 1094 (Pubitemid 47410272)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
25
-
-
65249121864
-
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
-
S. Dhawan, S.I. Tschen, and A. Bhushan Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation Genes Dev. 23 2009 906 911
-
(2009)
Genes Dev.
, vol.23
, pp. 906-911
-
-
Dhawan, S.1
Tschen, S.I.2
Bhushan, A.3
-
26
-
-
34249080596
-
Theoretical Analysis of Epigenetic Cell Memory by Nucleosome Modification
-
DOI 10.1016/j.cell.2007.02.053, PII S0092867407004588
-
I.B. Dodd, M.A. Micheelsen, K. Sneppen, and G. Thon Theoretical analysis of epigenetic cell memory by nucleosome modification Cell 129 2007 813 822 (Pubitemid 46802381)
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 813-822
-
-
Dodd, I.B.1
Micheelsen, M.A.2
Sneppen, K.3
Thon, G.4
-
27
-
-
67650076211
-
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting
-
M.E. Donohoe, S.S. Silva, S.F. Pinter, N. Xu, and J.T. Lee The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting Nature 460 2009 128 132
-
(2009)
Nature
, vol.460
, pp. 128-132
-
-
Donohoe, M.E.1
Silva, S.S.2
Pinter, S.F.3
Xu, N.4
Lee, J.T.5
-
28
-
-
77956362155
-
Protein homeostasis and aging in neurodegeneration
-
P.M. Douglas, and A. Dillin Protein homeostasis and aging in neurodegeneration J. Cell Biol. 190 2010 719 729
-
(2010)
J. Cell Biol.
, vol.190
, pp. 719-729
-
-
Douglas, P.M.1
Dillin, A.2
-
29
-
-
78049414227
-
Epigenetic reprogramming in plant and animal development
-
S. Feng, S.E. Jacobsen, and W. Reik Epigenetic reprogramming in plant and animal development Science 330 2010 622 627
-
(2010)
Science
, vol.330
, pp. 622-627
-
-
Feng, S.1
Jacobsen, S.E.2
Reik, W.3
-
30
-
-
50049116926
-
C. elegans dauer formation and the molecular basis of plasticity
-
N. Fielenbach, and A. Antebi C. elegans dauer formation and the molecular basis of plasticity Genes Dev. 22 2008 2149 2165
-
(2008)
Genes Dev.
, vol.22
, pp. 2149-2165
-
-
Fielenbach, N.1
Antebi, A.2
-
31
-
-
0013472626
-
Parabiosis in physiological studies
-
J.C. Finerty Parabiosis in physiological studies Physiol. Rev. 32 1952 277 302
-
(1952)
Physiol. Rev.
, vol.32
, pp. 277-302
-
-
Finerty, J.C.1
-
32
-
-
77951176737
-
Extending healthy life span - From yeast to humans
-
L. Fontana, L. Partridge, and V.D. Longo Extending healthy life span - from yeast to humans Science 328 2010 321 326
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
34
-
-
39049103917
-
Chromatin structure and the regulation of gene expression: The lessons of PEV in Drosophila
-
J.R. Girton, and K.M. Johansen Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila Adv. Genet. 61 2008 1 43
-
(2008)
Adv. Genet.
, vol.61
, pp. 1-43
-
-
Girton, J.R.1
Johansen, K.M.2
-
35
-
-
77954660029
-
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
-
E.L. Greer, T.J. Maures, A.G. Hauswirth, E.M. Green, D.S. Leeman, G.S. Maro, S. Han, M.R. Banko, O. Gozani, and A. Brunet Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans Nature 466 2010 383 387
-
(2010)
Nature
, vol.466
, pp. 383-387
-
-
Greer, E.L.1
Maures, T.J.2
Hauswirth, A.G.3
Green, E.M.4
Leeman, D.S.5
Maro, G.S.6
Han, S.7
Banko, M.R.8
Gozani, O.9
Brunet, A.10
-
36
-
-
81555214034
-
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
-
E.L. Greer, T.J. Maures, D. Ucar, A.G. Hauswirth, E. Mancini, J.P. Lim, B.A. Benayoun, Y. Shi, and A. Brunet Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans Nature 479 2011 365 371
-
(2011)
Nature
, vol.479
, pp. 365-371
-
-
Greer, E.L.1
Maures, T.J.2
Ucar, D.3
Hauswirth, A.G.4
Mancini, E.5
Lim, J.P.6
Benayoun, B.A.7
Shi, Y.8
Brunet, A.9
-
38
-
-
0000331391
-
Adult frogs derived from the nuclei of single somatic cells
-
J.B. Gurdon Adult frogs derived from the nuclei of single somatic cells Dev. Biol. 4 1962 256 273
-
(1962)
Dev. Biol.
, vol.4
, pp. 256-273
-
-
Gurdon, J.B.1
-
39
-
-
78649350746
-
The aging stress response
-
M.C. Haigis, and B.A. Yankner The aging stress response Mol. Cell 40 2010 333 344
-
(2010)
Mol. Cell
, vol.40
, pp. 333-344
-
-
Haigis, M.C.1
Yankner, B.A.2
-
40
-
-
78149487692
-
Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
-
J.H. Hanna, K. Saha, and R. Jaenisch Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues Cell 143 2010 508 525
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J.H.1
Saha, K.2
Jaenisch, R.3
-
41
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
D.E. Harrison, R. Strong, Z.D. Sharp, J.F. Nelson, C.M. Astle, K. Flurkey, N.L. Nadon, J.E. Wilkinson, K. Frenkel, and C.S. Carter Rapamycin fed late in life extends lifespan in genetically heterogeneous mice Nature 460 2009 392 395
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
Nadon, N.L.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
-
42
-
-
34249672703
-
Biological aging is no longer an unsolved problem
-
DOI 10.1196/annals.1395.001, Biogerontology: Mechanisms and Interventions
-
L. Hayflick Biological aging is no longer an unsolved problem Ann. N Y Acad. Sci. 1100 2007 1 13 (Pubitemid 47092635)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1100
, pp. 1-13
-
-
Hayflick, L.1
-
43
-
-
34248517504
-
Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: Evidence for a causal role in muscle fiber loss
-
A. Herbst, J.W. Pak, D. McKenzie, E. Bua, M. Bassiouni, and J.M. Aiken Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss J. Gerontol. A Biol. Sci. Med. Sci. 62 2007 235 245 (Pubitemid 47065720)
-
(2007)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.62
, Issue.3
, pp. 235-245
-
-
Herbst, A.1
Pak, J.W.2
McKenzie, D.3
Bua, E.4
Bassiouni, M.5
Aiken, J.M.6
-
44
-
-
78649339069
-
Long noncoding RNA in genome regulation: Prospects and mechanisms
-
T. Hung, and H.Y. Chang Long noncoding RNA in genome regulation: prospects and mechanisms RNA Biol. 7 2010 582 585
-
(2010)
RNA Biol.
, vol.7
, pp. 582-585
-
-
Hung, T.1
Chang, H.Y.2
-
45
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
M. Ieda, J.D. Fu, P. Delgado-Olguin, V. Vedantham, Y. Hayashi, B.G. Bruneau, and D. Srivastava Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors Cell 142 2010 375 386
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.D.2
Delgado-Olguin, P.3
Vedantham, V.4
Hayashi, Y.5
Bruneau, B.G.6
Srivastava, D.7
-
46
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
M. Jaskelioff, F.L. Muller, J.H. Paik, E. Thomas, S. Jiang, A.C. Adams, E. Sahin, M. Kost-Alimova, A. Protopopov, and J. Cadiñanos Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice Nature 469 2011 102 106
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.H.3
Thomas, E.4
Jiang, S.5
Adams, A.C.6
Sahin, E.7
Kost-Alimova, M.8
Protopopov, A.9
Cadiñanos, J.10
-
47
-
-
79955511101
-
Emerging models and paradigms for stem cell ageing
-
D.L. Jones, and T.A. Rando Emerging models and paradigms for stem cell ageing Nat. Cell Biol. 13 2011 506 512
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 506-512
-
-
Jones, D.L.1
Rando, T.A.2
-
48
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
DOI 10.1101/gad.13.19.2570
-
M. Kaeberlein, M. McVey, and L. Guarente The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev. 13 1999 2570 2580 (Pubitemid 29489648)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
49
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
DOI 10.1016/j.cub.2004.03.059, PII S0960982204002386
-
P. Kapahi, B.M. Zid, T. Harper, D. Koslover, V. Sapin, and S. Benzer Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway Curr. Biol. 14 2004 885 890 (Pubitemid 38800910)
-
(2004)
Current Biology
, vol.14
, Issue.10
, pp. 885-890
-
-
Kapahi, P.1
Zid, B.M.2
Harper, T.3
Koslover, D.4
Sapin, V.5
Benzer, S.6
-
50
-
-
77952923018
-
Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age
-
A.L. Kauffman, J.M. Ashraf, M.R. Corces-Zimmerman, J.N. Landis, and C.T. Murphy Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age PLoS Biol. 8 2010 e1000372
-
(2010)
PLoS Biol.
, vol.8
, pp. 1000372
-
-
Kauffman, A.L.1
Ashraf, J.M.2
Corces-Zimmerman, M.R.3
Landis, J.N.4
Murphy, C.T.5
-
51
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
-
T.L. Kawahara, E. Michishita, A.S. Adler, M. Damian, E. Berber, M. Lin, R.A. McCord, K.C. Ongaigui, L.D. Boxer, H.Y. Chang, and K.F. Chua SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span Cell 136 2009 62 74
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
Chua, K.F.11
-
52
-
-
77950200010
-
The genetics of ageing
-
C.J. Kenyon The genetics of ageing Nature 464 2010 504 512
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
53
-
-
0030813398
-
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
DOI 10.1126/science.277.5328.942
-
K.D. Kimura, H.A. Tissenbaum, Y. Liu, and G. Ruvkun daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans Science 277 1997 942 946 (Pubitemid 27366677)
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
54
-
-
13944262937
-
Understanding the odd science of aging
-
DOI 10.1016/j.cell.2005.01.027
-
T.B. Kirkwood Understanding the odd science of aging Cell 120 2005 437 447 (Pubitemid 40269759)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
55
-
-
77956238806
-
The connections between general and reproductive senescence and the evolutionary basis of menopause
-
T.B. Kirkwood, and D.P. Shanley The connections between general and reproductive senescence and the evolutionary basis of menopause Ann. N Y Acad. Sci. 1204 2010 21 29
-
(2010)
Ann. N y Acad. Sci.
, vol.1204
, pp. 21-29
-
-
Kirkwood, T.B.1
Shanley, D.P.2
-
56
-
-
79251498807
-
Protein homeostasis and aging: The importance of exquisite quality control
-
H. Koga, S. Kaushik, and A.M. Cuervo Protein homeostasis and aging: The importance of exquisite quality control Ageing Res. Rev. 10 2011 205 215
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 205-215
-
-
Koga, H.1
Kaushik, S.2
Cuervo, A.M.3
-
57
-
-
84900969225
-
Ink4a/Arf expression is a biomarker of aging
-
DOI 10.1172/JCI200422475
-
J. Krishnamurthy, C. Torrice, M.R. Ramsey, G.I. Kovalev, K. Al-Regaiey, L. Su, and N.E. Sharpless Ink4a/Arf expression is a biomarker of aging J. Clin. Invest. 114 2004 1299 1307 (Pubitemid 40385301)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1299-1307
-
-
Krishnamurthy, J.1
Torrice, C.2
Ramsey, M.R.3
Kovalev, G.I.4
Al-Regaiey, K.5
Su, L.6
Sharpless, N.E.7
-
58
-
-
69349098834
-
Stem cells: The promises and perils of p53
-
V. Krizhanovsky, and S.W. Lowe Stem cells: The promises and perils of p53 Nature 460 2009 1085 1086
-
(2009)
Nature
, vol.460
, pp. 1085-1086
-
-
Krizhanovsky, V.1
Lowe, S.W.2
-
60
-
-
27744555810
-
Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs
-
DOI 10.1038/nature04120, PII N04120
-
N. Lee, C. Maurange, L. Ringrose, and R. Paro Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs Nature 438 2005 234 237 (Pubitemid 41599876)
-
(2005)
Nature
, vol.438
, Issue.7065
, pp. 234-237
-
-
Lee, N.1
Maurange, C.2
Ringrose, L.3
Paro, R.4
-
61
-
-
60549100158
-
Systematic identification of cis-silenced genes by trans complementation
-
J.H. Lee, B. Bugarija, E.J. Millan, N.M. Walton, J. Gaetz, C.J. Fernandes, W.H. Yu, N. Mekel-Bobrov, T.W. Vallender, and G.E. Snyder Systematic identification of cis-silenced genes by trans complementation Hum. Mol. Genet. 18 2009 835 846
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 835-846
-
-
Lee, J.H.1
Bugarija, B.2
Millan, E.J.3
Walton, N.M.4
Gaetz, J.5
Fernandes, C.J.6
Yu, W.H.7
Mekel-Bobrov, N.8
Vallender, T.W.9
Snyder, G.E.10
-
62
-
-
67649834758
-
Chromatin analysis of occluded genes
-
J.H. Lee, J. Gaetz, B. Bugarija, C.J. Fernandes, G.E. Snyder, E.C. Bush, and B.T. Lahn Chromatin analysis of occluded genes Hum. Mol. Genet. 18 2009 2567 2574
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2567-2574
-
-
Lee, J.H.1
Gaetz, J.2
Bugarija, B.3
Fernandes, C.J.4
Snyder, G.E.5
Bush, E.C.6
Lahn, B.T.7
-
63
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
S.J. Lin, P.A. Defossez, and L. Guarente Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Science 289 2000 2126 2128
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
64
-
-
79955513612
-
Manifestations and mechanisms of stem cell aging
-
L. Liu, and T.A. Rando Manifestations and mechanisms of stem cell aging J. Cell Biol. 193 2011 257 266
-
(2011)
J. Cell Biol.
, vol.193
, pp. 257-266
-
-
Liu, L.1
Rando, T.A.2
-
65
-
-
77956261391
-
Recreating pluripotency?
-
K.M. Loh, and B. Lim Recreating pluripotency? Cell Stem Cell 7 2010 137 139
-
(2010)
Cell Stem Cell
, vol.7
, pp. 137-139
-
-
Loh, K.M.1
Lim, B.2
-
66
-
-
77957797819
-
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance
-
S. Luo, G.A. Kleemann, J.M. Ashraf, W.M. Shaw, and C.T. Murphy TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance Cell 143 2010 299 312
-
(2010)
Cell
, vol.143
, pp. 299-312
-
-
Luo, S.1
Kleemann, G.A.2
Ashraf, J.M.3
Shaw, W.M.4
Murphy, C.T.5
-
67
-
-
77649240380
-
Widespread and tissue specific age-related DNA methylation changes in mice
-
S. Maegawa, G. Hinkal, H.S. Kim, L. Shen, L. Zhang, J. Zhang, N. Zhang, S. Liang, L.A. Donehower, and J.P. Issa Widespread and tissue specific age-related DNA methylation changes in mice Genome Res. 20 2010 332 340
-
(2010)
Genome Res.
, vol.20
, pp. 332-340
-
-
Maegawa, S.1
Hinkal, G.2
Kim, H.S.3
Shen, L.4
Zhang, L.5
Zhang, J.6
Zhang, N.7
Liang, S.8
Donehower, L.A.9
Issa, J.P.10
-
68
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
R. Margueron, and D. Reinberg The Polycomb complex PRC2 and its mark in life Nature 469 2011 343 349
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
69
-
-
77952240404
-
Telomere rejuvenation during nuclear reprogramming
-
R.M. Marión, and M.A. Blasco Telomere rejuvenation during nuclear reprogramming Curr. Opin. Genet. Dev. 20 2010 190 196
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 190-196
-
-
Marión, R.M.1
Blasco, M.A.2
-
70
-
-
74049087181
-
Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging
-
G.M. Martin Epigenetic gambling and epigenetic drift as an antagonistic pleiotropic mechanism of aging Aging Cell 8 2009 761 764
-
(2009)
Aging Cell
, vol.8
, pp. 761-764
-
-
Martin, G.M.1
-
71
-
-
14344264665
-
Parabiosis between old and young rats
-
C.M. McCay, F. Pope, W. Lunsford, G. Sperling, and P. Sambhavaphol Parabiosis between old and young rats Gerontologia 1 1957 7 17
-
(1957)
Gerontologia
, vol.1
, pp. 7-17
-
-
McCay, C.M.1
Pope, F.2
Lunsford, W.3
Sperling, G.4
Sambhavaphol, P.5
-
72
-
-
77957970498
-
Epigenetic modifications in pluripotent and differentiated cells
-
A. Meissner Epigenetic modifications in pluripotent and differentiated cells Nat. Biotechnol. 28 2010 1079 1088
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1079-1088
-
-
Meissner, A.1
-
73
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
DOI 10.1038/nature06736, PII NATURE06736
-
E. Michishita, R.A. McCord, E. Berber, M. Kioi, H. Padilla-Nash, M. Damian, P. Cheung, R. Kusumoto, T.L. Kawahara, and J.C. Barrett SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin Nature 452 2008 492 496 (Pubitemid 351450840)
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.A.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
74
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
DOI 10.1038/nature07056, PII NATURE07056
-
T.S. Mikkelsen, J. Hanna, X. Zhang, M. Ku, M. Wernig, P. Schorderet, B.E. Bernstein, R. Jaenisch, E.S. Lander, and A. Meissner Dissecting direct reprogramming through integrative genomic analysis Nature 454 2008 49 55 (Pubitemid 351931978)
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
75
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
DOI 10.1016/j.cell.2005.11.044, PII S0092867406000493
-
R. Mostoslavsky, K.F. Chua, D.B. Lombard, W.W. Pang, M.R. Fischer, L. Gellon, P. Liu, G. Mostoslavsky, S. Franco, and M.M. Murphy Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 Cell 124 2006 315 329 (Pubitemid 43121980)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.-L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
77
-
-
52249096815
-
Molecular coupling of Xist regulation and pluripotency
-
P. Navarro, I. Chambers, V. Karwacki-Neisius, C. Chureau, C. Morey, C. Rougeulle, and P. Avner Molecular coupling of Xist regulation and pluripotency Science 321 2008 1693 1695
-
(2008)
Science
, vol.321
, pp. 1693-1695
-
-
Navarro, P.1
Chambers, I.2
Karwacki-Neisius, V.3
Chureau, C.4
Morey, C.5
Rougeulle, C.6
Avner, P.7
-
78
-
-
34548150187
-
The role of nuclear architecture in genomic instability and ageing
-
DOI 10.1038/nrm2238, PII NRM2238
-
P. Oberdoerffer, and D.A. Sinclair The role of nuclear architecture in genomic instability and ageing Nat. Rev. Mol. Cell Biol. 8 2007 692 702 (Pubitemid 47312825)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 692-702
-
-
Oberdoerffer, P.1
Sinclair, D.A.2
-
79
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
P. Oberdoerffer, S. Michan, M. McVay, R. Mostoslavsky, J. Vann, S.K. Park, A. Hartlerode, J. Stegmuller, A. Hafner, and P. Loerch SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging Cell 135 2008 907 918
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
-
80
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
DOI 10.1038/nature05934, PII NATURE05934
-
K. Okita, T. Ichisaka, and S. Yamanaka Generation of germline-competent induced pluripotent stem cells Nature 448 2007 313 317 (Pubitemid 47080336)
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
81
-
-
78649650475
-
Noncoding RNA landmarks of pluripotency and reprogramming
-
Z. Ouyang, G.X. Zheng, and H.Y. Chang Noncoding RNA landmarks of pluripotency and reprogramming Cell Stem Cell 7 2010 649 650
-
(2010)
Cell Stem Cell
, vol.7
, pp. 649-650
-
-
Ouyang, Z.1
Zheng, G.X.2
Chang, H.Y.3
-
82
-
-
79960073520
-
Using heterokaryons to understand pluripotency and reprogramming
-
F.M. Piccolo, C.F. Pereira, I. Cantone, K. Brown, T. Tsubouchi, J. Soza-Ried, M. Merkenschlager, and A.G. Fisher Using heterokaryons to understand pluripotency and reprogramming Philos. Trans. R. Soc. Lond. B Biol. Sci. 366 2011 2260 2265
-
(2011)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.366
, pp. 2260-2265
-
-
Piccolo, F.M.1
Pereira, C.F.2
Cantone, I.3
Brown, K.4
Tsubouchi, T.5
Soza-Ried, J.6
Merkenschlager, M.7
Fisher, A.G.8
-
83
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
A. Rada-Iglesias, R. Bajpai, T. Swigut, S.A. Brugmann, R.A. Flynn, and J. Wysocka A unique chromatin signature uncovers early developmental enhancers in humans Nature 470 2011 279 283
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
84
-
-
33745614062
-
Stem cells, ageing and the quest for immortality
-
DOI 10.1038/nature04958, PII N04958
-
T.A. Rando Stem cells, ageing and the quest for immortality Nature 441 2006 1080 1086 (Pubitemid 43990720)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1080-1086
-
-
Rando, T.A.1
-
85
-
-
67650711140
-
Genome-wide views of chromatin structure
-
O.J. Rando, and H.Y. Chang Genome-wide views of chromatin structure Annu. Rev. Biochem. 78 2009 245 271
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 245-271
-
-
Rando, O.J.1
Chang, H.Y.2
-
86
-
-
33847208871
-
Timescales of genetic and epigenetic inheritance
-
O.J. Rando, and K.J. Verstrepen Timescales of genetic and epigenetic inheritance Cell 128 2007 655 668
-
(2007)
Cell
, vol.128
, pp. 655-668
-
-
Rando, O.J.1
Verstrepen, K.J.2
-
87
-
-
0035839106
-
Nuclear cloning and epigenetic reprogramming of the genome
-
DOI 10.1126/science.1063206
-
W.M. Rideout III, K. Eggan, and R. Jaenisch Nuclear cloning and epigenetic reprogramming of the genome Science 293 2001 1093 1098 (Pubitemid 32758082)
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1093-1098
-
-
Rideout III, W.M.1
Eggan, K.2
Jaenisch, R.3
-
89
-
-
0035176425
-
Stem cells from the mammalian blastocyst
-
J. Rossant Stem cells from the Mammalian blastocyst Stem Cells 19 2001 477 482 (Pubitemid 33095842)
-
(2001)
Stem Cells
, vol.19
, Issue.6
, pp. 477-482
-
-
Rossant, J.1
-
90
-
-
33846019277
-
Methylation of Lysine 4 on Histone H3: Intricacy of Writing and Reading a Single Epigenetic Mark
-
DOI 10.1016/j.molcel.2006.12.014, PII S1097276506008720
-
A.J. Ruthenburg, C.D. Allis, and J. Wysocka Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark Mol. Cell 25 2007 15 30 (Pubitemid 46049068)
-
(2007)
Molecular Cell
, vol.25
, Issue.1
, pp. 15-30
-
-
Ruthenburg, A.J.1
Allis, C.D.2
Wysocka, J.3
-
91
-
-
45849129481
-
Germination, genetics, and growth of an ancient date seed
-
DOI 10.1126/science.1153600
-
S. Sallon, E. Solowey, Y. Cohen, R. Korchinsky, M. Egli, I. Woodhatch, O. Simchoni, and M. Kislev Germination, genetics, and growth of an ancient date seed Science 320 2008 1464 (Pubitemid 351929420)
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1464
-
-
Sallon, S.1
Solowey, E.2
Cohen, Y.3
Korchinsky, R.4
Egli, M.5
Woodhatch, I.6
Simchoni, O.7
Kislev, M.8
-
92
-
-
75749104729
-
DNMT1 maintains progenitor function in self-renewing somatic tissue
-
G.L. Sen, J.A. Reuter, D.E. Webster, L. Zhu, and P.A. Khavari DNMT1 maintains progenitor function in self-renewing somatic tissue Nature 463 2010 563 567
-
(2010)
Nature
, vol.463
, pp. 563-567
-
-
Sen, G.L.1
Reuter, J.A.2
Webster, D.E.3
Zhu, L.4
Khavari, P.A.5
-
93
-
-
79952260454
-
The DNA damage response: Balancing the scale between cancer and ageing
-
E.G. Seviour, and S.Y. Lin The DNA damage response: Balancing the scale between cancer and ageing Aging (Albany NY) 2 2010 900 907
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 900-907
-
-
Seviour, E.G.1
Lin, S.Y.2
-
94
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
DOI 10.1038/nrm2241, PII NRM2241
-
N.E. Sharpless, and R.A. DePinho How stem cells age and why this makes us grow old Nat. Rev. Mol. Cell Biol. 8 2007 703 713 (Pubitemid 47312828)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 703-713
-
-
Sharpless, N.E.1
DePinho, R.A.2
-
95
-
-
0031459980
-
Extrachromosomal rDNA circles - A cause of aging in yeast
-
DOI 10.1016/S0092-8674(00)80493-6
-
D.A. Sinclair, and L. Guarente Extrachromosomal rDNA circles - a cause of aging in yeast Cell 91 1997 1033 1042 (Pubitemid 28027835)
-
(1997)
Cell
, vol.91
, Issue.7
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
96
-
-
77958569435
-
Induced pluripotency: History, mechanisms, and applications
-
M. Stadtfeld, and K. Hochedlinger Induced pluripotency: history, mechanisms, and applications Genes Dev. 24 2010 2239 2263
-
(2010)
Genes Dev.
, vol.24
, pp. 2239-2263
-
-
Stadtfeld, M.1
Hochedlinger, K.2
-
97
-
-
0035797898
-
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
-
DOI 10.1016/S0960-9822(01)00459-6
-
M. Tada, Y. Takahama, K. Abe, N. Nakatsuji, and T. Tada Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells Curr. Biol. 11 2001 1553 1558 (Pubitemid 32931020)
-
(2001)
Current Biology
, vol.11
, Issue.19
, pp. 1553-1558
-
-
Tada, M.1
Takahama, Y.2
Abe, K.3
Nakatsuji, N.4
Tada, T.5
-
98
-
-
33747195353
-
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
-
DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676 (Pubitemid 44233629)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
99
-
-
0017725251
-
Change of the hepatic cells in parabiosis between old and young rats
-
H. Tauchi, and K. Hasegawa Change of the hepatic cells in parabiosis between old and young rats Mech. Ageing Dev. 6 1977 333 339 (Pubitemid 8154581)
-
(1977)
Mechanisms of Ageing and Development
, vol.6
, Issue.5
, pp. 333-339
-
-
Tauchi, H.1
Hasegawa, K.2
-
100
-
-
78650889400
-
Chromatin regulation and genome maintenance by mammalian SIRT6
-
R.I. Tennen, and K.F. Chua Chromatin regulation and genome maintenance by mammalian SIRT6 Trends Biochem. Sci. 36 2011 39 46
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 39-46
-
-
Tennen, R.I.1
Chua, K.F.2
-
101
-
-
33745186492
-
Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming
-
DOI 10.1242/jcs.02945
-
R. Terranova, C.F. Pereira, C. Du Roure, M. Merkenschlager, and A.G. Fisher Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming J. Cell Sci. 119 2006 2065 2072 (Pubitemid 43904961)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.10
, pp. 2065-2072
-
-
Terranova, R.1
Pereira, C.F.2
Du Roure, C.3
Merkenschlager, M.4
Fisher, A.G.5
-
102
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
DOI 10.1038/35065638
-
H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 2001 227 230 (Pubitemid 32216597)
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
103
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
DOI 10.1038/nature02517
-
A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, M. Bohlooly-Y, S. Gidlöf, A. Oldfors, and R. Wibom Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423 (Pubitemid 38715133)
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly-Y, M.7
Gldlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.-G.13
-
104
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
J.J. Trowbridge, J.W. Snow, J. Kim, and S.H. Orkin DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells Cell Stem Cell 5 2009 442 449
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
105
-
-
69249235740
-
Calorie restriction and the exercise of chromatin
-
A. Vaquero, and D. Reinberg Calorie restriction and the exercise of chromatin Genes Dev. 23 2009 1849 1869
-
(2009)
Genes Dev.
, vol.23
, pp. 1849-1869
-
-
Vaquero, A.1
Reinberg, D.2
-
106
-
-
77950866717
-
Chromatin signature of embryonic pluripotency is established during genome activation
-
N.L. Vastenhouw, Y. Zhang, I.G. Woods, F. Imam, A. Regev, X.S. Liu, J. Rinn, and A.F. Schier Chromatin signature of embryonic pluripotency is established during genome activation Nature 464 2010 922 926
-
(2010)
Nature
, vol.464
, pp. 922-926
-
-
Vastenhouw, N.L.1
Zhang, Y.2
Woods, I.G.3
Imam, F.4
Regev, A.5
Liu, X.S.6
Rinn, J.7
Schier, A.F.8
-
108
-
-
80052410357
-
Age-related changes in the systemic milieu regulate adult neurogenesis
-
S.A. Villeda, J. Luo, M. Britschgi, J.-S. Park, Z. Ding, J.L. Grant, S. Couillard-Despres, L. Aigner, T.A. Rando, and A. Wyss-Coray Age-related changes in the systemic milieu regulate adult neurogenesis Nature 477 2011 90 94
-
(2011)
Nature
, vol.477
, pp. 90-94
-
-
Villeda, S.A.1
Luo, J.2
Britschgi, M.3
Park, J.-S.4
Ding, Z.5
Grant, J.L.6
Couillard-Despres, S.7
Aigner, L.8
Rando, T.A.9
Wyss-Coray, A.10
-
109
-
-
0034687374
-
Isolation of a 250 million-year-old halotolerant bacterium from a primary salt crystal
-
R.H. Vreeland, W.D. Rosenzweig, and D.W. Powers Isolation of a 250 million-year-old halotolerant bacterium from a primary salt crystal Nature 407 2000 897 900
-
(2000)
Nature
, vol.407
, pp. 897-900
-
-
Vreeland, R.H.1
Rosenzweig, W.D.2
Powers, D.W.3
-
110
-
-
55849101681
-
Fat metabolism links germline stem cells and longevity in C. elegans
-
M.C. Wang, E.J. O'Rourke, and G. Ruvkun Fat metabolism links germline stem cells and longevity in C. elegans Science 322 2008 957 960
-
(2008)
Science
, vol.322
, pp. 957-960
-
-
Wang, M.C.1
O'Rourke, E.J.2
Ruvkun, G.3
-
111
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
DOI 10.1038/ng.154, PII NG154
-
Z. Wang, C. Zang, J.A. Rosenfeld, D.E. Schones, A. Barski, S. Cuddapah, K. Cui, T.Y. Roh, W. Peng, M.Q. Zhang, and K. Zhao Combinatorial patterns of histone acetylations and methylations in the human genome Nat. Genet. 40 2008 897 903 (Pubitemid 351913645)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
Roh, T.-Y.8
Peng, W.9
Zhang, M.Q.10
Zhao, K.11
-
112
-
-
79952660821
-
Control of the embryonic stem cell state
-
R.A. Young Control of the embryonic stem cell state Cell 144 2011 940 954
-
(2011)
Cell
, vol.144
, pp. 940-954
-
-
Young, R.A.1
-
113
-
-
38949212767
-
Human embryonic stem cells: Mechanisms to escape replicative senescence?
-
DOI 10.1007/s12015-007-9005-x
-
X. Zeng Human embryonic stem cells: mechanisms to escape replicative senescence? Stem Cell Rev. 3 2007 270 279 (Pubitemid 351526204)
-
(2007)
Stem Cell Reviews
, vol.3
, Issue.4
, pp. 270-279
-
-
Zeng, X.1
|