-
1
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. (2002) DNA methylation patterns and epigenetic memory. Genes Dev., 16, 6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
2
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Goll, M.G. and Bestor, T.H. (2005) Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem., 74, 481-514.
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
3
-
-
77957021225
-
DNA methylation and cellular reprogramming
-
De Carvalho, D.D., You, J.S. and Jones, P.A. (2010) DNA methylation and cellular reprogramming. Trends Cell Biol., 20, 609-617.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 609-617
-
-
De Carvalho, D.D.1
You, J.S.2
Jones, P.A.3
-
4
-
-
79956330964
-
CpG islands and the regulation of transcription
-
Deaton, A.M. and Bird, A. (2011) CpG islands and the regulation of transcription. Genes Dev., 25, 1010-1022.
-
(2011)
Genes Dev
, vol.25
, pp. 1010-1022
-
-
Deaton, A.M.1
Bird, A.2
-
5
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
Wu, S.C. and Zhang, Y. (2010) Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol., 11, 607-620.
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
6
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald, J., Engemann, S., Lane, N., Mayer, W., Olek, A., Fundele, R., Dean, W., Reik, W. and Walter, J. (2000) Active demethylation of the paternal genome in the mouse zygote. Curr. Biol., 10, 475-478.
-
(2000)
Curr. Biol
, vol.10
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
Mayer, W.4
Olek, A.5
Fundele, R.6
Dean, W.7
Reik, W.8
Walter, J.9
-
7
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer, W., Niveleau, A., Walter, J., Fundele, R. and Haaf, T. (2000) Demethylation of the zygotic paternal genome. Nature, 403, 501-502.
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
8
-
-
17444409344
-
Epigenetic reprogramming in mammals
-
Morgan, H.D., Santos, F., Green, K., Dean, W. and Reik, W. (2005) Epigenetic reprogramming in mammals. Hum. Mol. Genet., 14, R47-R58.
-
(2005)
Hum. Mol. Genet
, vol.14
-
-
Morgan, H.D.1
Santos, F.2
Green, K.3
Dean, W.4
Reik, W.5
-
9
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty, M.M., Ganz, K., Powell, B.E., Hu, Y.C., Markoulaki, S., Cheng, A.W., Gao, Q., Kim, J., Choi, S.W., Page, D.C. et al. (2011) Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell, 9, 166-175.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
Hu, Y.C.4
Markoulaki, S.5
Cheng, A.W.6
Gao, Q.7
Kim, J.8
Choi, S.W.9
Page, D.C.10
-
10
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu, T.P., Guo, F., Yang, H., Wu, H.P., Xu, G.F., Liu, W., Xie, Z.G., Shi, L., He, X., Jin, S.G. et al. (2011) The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature, 477, 606-610.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
Liu, W.6
Xie, Z.G.7
Shi, L.8
He, X.9
Jin, S.G.10
-
11
-
-
82955207588
-
Mechanisms and functions of tet protein-mediated 5-methylcytosine oxidation
-
Wu, H. and Zhang, Y. (2011) Mechanisms and functions of tet protein-mediated 5-methylcytosine oxidation. Genes Dev., 25, 2436-2452.
-
(2011)
Genes Dev
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
12
-
-
0036768615
-
Epigenetic reprogramming in mouse primordial germ cells
-
Hajkova, P., Erhardt, S., Lane, N., Haaf, T., El-Maarri, O., Reik, W., Walter, J. and Surani, M.A. (2002) Epigenetic reprogramming in mouse primordial germ cells. Mech. Dev., 117, 15-23.
-
(2002)
Mech. Dev
, vol.117
, pp. 15-23
-
-
Hajkova, P.1
Erhardt, S.2
Lane, N.3
Haaf, T.4
El-Maarri, O.5
Reik, W.6
Walter, J.7
Surani, M.A.8
-
13
-
-
38349100549
-
Epigenetic events in mammalian germ-cell development: Reprogramming and beyond
-
Sasaki, H. and Matsui, Y. (2008) Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat. Rev. Genet., 9, 129-140.
-
(2008)
Nat. Rev. Genet
, vol.9
, pp. 129-140
-
-
Sasaki, H.1
Matsui, Y.2
-
14
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner, A., Mikkelsen, T.S., Gu, H., Wernig, M., Hanna, J., Sivachenko, A., Zhang, X., Bernstein, B.E., Nusbaum, C., Jaffe, D.B. et al. (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature, 454, 766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
-
15
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister, R., Pelizzola, M., Dowen, R.H., Hawkins, R.D., Hon, G., Tonti-Filippini, J., Nery, J.R., Lee, L., Ye, Z., Ngo, Q.M. et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature, 462, 315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
Tonti-Filippini, J.6
Nery, J.R.7
Lee, L.8
Ye, Z.9
Ngo, Q.M.10
-
16
-
-
84894277075
-
A symphony on C: Orchestrating DNA repair for gene expression via cytosine modification
-
Rots, M.G. and Peterson, S.K. (2013) A symphony on C: orchestrating DNA repair for gene expression via cytosine modification. Epigenomics, 5, 315-322.
-
(2013)
Epigenomics
, vol.5
, pp. 315-322
-
-
Rots, M.G.1
Peterson, S.K.2
-
17
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M., Koh, K.P., Shen, Y., Pastor, W.A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L.M., Liu, D.R., Aravind, L. et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science, 324, 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
-
18
-
-
34250317798
-
A new pyrimidine base from bacteriophage nucleic acids
-
Wyatt, G.R. and Cohen, S.S. (1952) A new pyrimidine base from bacteriophage nucleic acids. Nature, 170, 1072-1073.
-
(1952)
Nature
, vol.170
, pp. 1072-1073
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
19
-
-
0015298215
-
The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid
-
Penn, N.W., Suwalski, R., O'Riley, C., Bojanowski, K. and Yura, R. (1972) The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochem. J., 126, 781-790.
-
(1972)
Biochem. J
, vol.126
, pp. 781-790
-
-
Penn, N.W.1
Suwalski, R.2
Oriley, C.3
Bojanowski, K.4
Yura, R.5
-
20
-
-
0017111827
-
5-methylcytosine content in the vertebrate deoxyribonucleic acids: Species specificity
-
Kothari, R.M. and Shankar, V. (1976) 5-methylcytosine content in the vertebrate deoxyribonucleic acids: species specificity. J. Mol. Evol., 7, 325-329.
-
(1976)
J. Mol. Evol
, vol.7
, pp. 325-329
-
-
Kothari, R.M.1
Shankar, V.2
-
21
-
-
78650826181
-
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
-
Globisch, D., Munzel, M., Muller, M., Michalakis, S., Wagner, M., Koch, S., Bruckl, T., Biel, M. and Carell, T. (2010) Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS One, 5, e15367.
-
(2010)
PLoS One
, vol.5
-
-
Globisch, D.1
Munzel, M.2
Muller, M.3
Michalakis, S.4
Wagner, M.5
Koch, S.6
Bruckl, T.7
Biel, M.8
Carell, T.9
-
22
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis, S. and Heintz, N. (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 324, 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
23
-
-
84857891830
-
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
-
Nestor, C.E., Ottaviano, R., Reddington, J., Sproul, D., Reinhardt, D., Dunican, D., Katz, E., Dixon, J.M., Harrison, D.J. and Meehan, R.R. (2011) Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res., 22, 467-477.
-
(2011)
Genome Res
, vol.22
, pp. 467-477
-
-
Nestor, C.E.1
Ottaviano, R.2
Reddington, J.3
Sproul, D.4
Reinhardt, D.5
Dunican, D.6
Katz, E.7
Dixon, J.M.8
Harrison, D.J.9
Meehan, R.R.10
-
24
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song, C.X., Szulwach, K.E., Fu, Y., Dai, Q., Yi, C., Li, X., Li, Y., Chen, C.H., Zhang, W., Jian, X. et al. (2011) Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat. Biotechnol., 29, 68-72.
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
Dai, Q.4
Yi, C.5
Li, X.6
Li, Y.7
Chen, C.H.8
Zhang, W.9
Jian, X.10
-
25
-
-
78049401678
-
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA
-
Szwagierczak, A., Bultmann, S., Schmidt, C.S., Spada, F. and Leonhardt, H. (2010) Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res., 38, e181.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Szwagierczak, A.1
Bultmann, S.2
Schmidt, C.S.3
Spada, F.4
Leonhardt, H.5
-
26
-
-
77956189495
-
Role of tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito, S., D'Alessio, A.C., Taranova, O.V., Hong, K., Sowers, L.C. and Zhang, Y. (2010) Role of tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature, 466, 1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
27
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko, M., Huang, Y., Jankowska, A.M., Pape, U.J., Tahiliani, M., Bandukwala, H.S., An, J., Lamperti, E.D., Koh, K.P., Ganetzky, R. et al. (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature, 468, 839-843.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
An, J.7
Lamperti, E.D.8
Koh, K.P.9
Ganetzky, R.10
-
28
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D. et al. (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell, 146, 67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
-
29
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo, J.U., Su, Y., Zhong, C., Ming, G.L. and Song, H. (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell, 145, 423-434.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
30
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito, S., Shen, L., Dai, Q., Wu, S.C., Collins, L.B., Swenberg, J.A., He, C. and Zhang, Y. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science, 333, 1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
31
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He, Y.F., Li, B.Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L. et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science, 333, 1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
-
32
-
-
80052476744
-
Molecular biology. Demystifying DNA. Demethylation
-
Nabel, C.S. and Kohli, R.M. (2011) Molecular biology. demystifying DNA. Demethylation. Science, 333, 1229-1230.
-
(2011)
Science
, vol.333
, pp. 1229-1230
-
-
Nabel, C.S.1
Kohli, R.M.2
-
33
-
-
84862681459
-
Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing
-
Schiesser, S., Hackner, B., Pfaffeneder, T., Muller, M., Hagemeier, C., Truss, M. and Carell, T. (2012) Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing. Angew. Chem. Int. Ed Engl., 51, 6516-6520.
-
(2012)
Angew. Chem. Int. Ed Engl
, vol.51
, pp. 6516-6520
-
-
Schiesser, S.1
Hackner, B.2
Pfaffeneder, T.3
Muller, M.4
Hagemeier, C.5
Truss, M.6
Carell, T.7
-
34
-
-
80053917872
-
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites
-
Maiti, A. and Drohat, A.C. (2011) Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J. Biol. Chem., 286, 35334-35338.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 35334-35338
-
-
Maiti, A.1
Drohat, A.C.2
-
35
-
-
0032694084
-
DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
-
De Smet, C., Lurquin, C., Lethe, B., Martelange, V. and Boon, T. (1999) DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol. Cell Biol., 19, 7327-7335.
-
(1999)
Mol. Cell Biol
, vol.19
, pp. 7327-7335
-
-
De Smet, C.1
Lurquin, C.2
Lethe, B.3
Martelange, V.4
Boon, T.5
-
36
-
-
22844457491
-
DNA methylation and human disease
-
Robertson, K.D. (2005) DNA methylation and human disease. Nat. Rev. Genet., 6, 597-610.
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 597-610
-
-
Robertson, K.D.1
-
37
-
-
77956997072
-
Methylation of DNA in cancer
-
Watanabe, Y. and Maekawa, M. (2010) Methylation of DNA in cancer. Adv. Clin. Chem., 52, 145-167.
-
(2010)
Adv. Clin. Chem
, vol.52
, pp. 145-167
-
-
Watanabe, Y.1
Maekawa, M.2
-
38
-
-
84870583474
-
Epigenetic editing: Targeted rewriting of epigenetic marks to modulate expression of selected target genes
-
de Groote, M.L., Verschure, P.J. and Rots, M.G. (2012) Epigenetic editing: Targeted rewriting of epigenetic marks to modulate expression of selected target genes. Nucleic Acids Res., 40, 10596-10613.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10596-10613
-
-
De Groote, M.L.1
Verschure, P.J.2
Rots, M.G.3
-
39
-
-
35848968022
-
Histone H3 Arg2 methylation provides alternative directions for COMPASS
-
Klose, R.J. and Zhang, Y. (2007) Histone H3 Arg2 methylation provides alternative directions for COMPASS. Nat. Struct. Mol. Biol., 14, 1058-1060.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 1058-1060
-
-
Klose, R.J.1
Zhang, Y.2
-
40
-
-
84894280654
-
Re-expression of epigenetically silenced ICAM-1 elucidates its cell-biological role in ovarian cancer cells
-
July 5 doi:10.1002/ijc.28375; Epub ahead of print
-
de Groote, M.L., Kazemier, H.G., Huisman, C., Van der Gun, B.T.F., Faas, M.M. and Rots, M.G. (2013) Re-expression of epigenetically silenced ICAM-1 elucidates its cell-biological role in ovarian cancer cells. Int. J. Cancer, July 5 (doi:10.1002/ijc.28375; Epub ahead of print).
-
(2013)
Int. J. Cancer
-
-
De Groote, M.L.1
Kazemier, H.G.2
Huisman, C.3
Van Der Gun, B.T.F.4
Faas, M.M.5
Rots, M.G.6
-
41
-
-
84875213177
-
Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer
-
van der Gun, B.T.F., Huisman, C., Stolzenburg, S., Kazemier, H.G., Ruiters, M.H., Blancafort, P. and Rots, M.G. (2013) Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer. Br. J. Cancer, 108, 881-886.
-
(2013)
Br. J. Cancer
, vol.108
, pp. 881-886
-
-
Van Der Gun, B.T.F.1
Huisman, C.2
Stolzenburg, S.3
Kazemier, H.G.4
Ruiters, M.H.5
Blancafort, P.6
Rots, M.G.7
-
42
-
-
4344685148
-
Vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation
-
Magnenat, L., Blancafort, P. and Barbas, C.F. 3rd (2004) In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation. J. Mol. Biol., 341, 635-649.
-
(2004)
J. Mol. Biol
, vol.341
, pp. 635-649
-
-
Magnenat, L.1
Blancafort, P.2
Barbas III, C.F.3
-
43
-
-
84878108856
-
Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by artificial transcription factors
-
Huisman, C., Wisman, G.B., Kazemier, H.G., van Vugt, M.A., van der Zee, A.G., Schuuring, E. and Rots, M.G. (2013) Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by artificial transcription factors. Mol. Oncol., 7, 669-679.
-
(2013)
Mol. Oncol
, vol.7
, pp. 669-679
-
-
Huisman, C.1
Wisman, G.B.2
Kazemier, H.G.3
Van Vugt, M.A.4
Van Der Zee, A.G.5
Schuuring, E.6
Rots, M.G.7
-
44
-
-
84861221693
-
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
-
Booth, M.J., Branco, M.R., Ficz, G., Oxley, D., Krueger, F., Reik, W. and Balasubramanian, S. (2012) Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science, 336, 934-937.
-
(2012)
Science
, vol.336
, pp. 934-937
-
-
Booth, M.J.1
Branco, M.R.2
Ficz, G.3
Oxley, D.4
Krueger, F.5
Reik, W.6
Balasubramanian, S.7
-
45
-
-
84856058152
-
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
-
Haffner, M.C., Chaux, A., Meeker, A.K., Esopi, D.M., Gerber, J., Pellakuru, L.G., Toubaji, A., Argani, P., Iacobuzio-Donahue, C., Nelson, W.G. et al. (2011) Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget, 2, 627-637.
-
(2011)
Oncotarget
, vol.2
, pp. 627-637
-
-
Haffner, M.C.1
Chaux, A.2
Meeker, A.K.3
Esopi, D.M.4
Gerber, J.5
Pellakuru, L.G.6
Toubaji, A.7
Argani, P.8
Iacobuzio-Donahue, C.9
Nelson, W.G.10
-
46
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5- methylcytosine hydroxylation
-
Yang, H., Liu, Y., Bai, F., Zhang, J.Y., Ma, S.H., Liu, J., Xu, Z.D., Zhu, H.G., Ling, Z.Q., Ye, D. et al. (2013) Tumor development is associated with decrease of TET gene expression and 5- methylcytosine hydroxylation. Oncogene, 32, 663-669.
-
(2013)
Oncogene
, vol.32
, pp. 663-669
-
-
Yang, H.1
Liu, Y.2
Bai, F.3
Zhang, J.Y.4
Ma, S.H.5
Liu, J.6
Xu, Z.D.7
Zhu, H.G.8
Ling, Z.Q.9
Ye, D.10
-
47
-
-
79960203733
-
Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer
-
van der Gun, B.T., de Groote, M.L., Kazemier, H.G., Arendzen, A.J., Terpstra, P., Ruiters, M.H., McLaughlin, P.M. and Rots, M.G. (2011) Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer. Br. J. Cancer, 105, 312-319.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 312-319
-
-
Van Der Gun, B.T.1
De Groote, M.L.2
Kazemier, H.G.3
Arendzen, A.J.4
Terpstra, P.5
Ruiters, M.H.6
McLaughlin, P.M.7
Rots, M.G.8
-
48
-
-
8744318619
-
The human L1 promoter: Variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity
-
Lavie, L., Maldener, E., Brouha, B., Meese, E. and Mayer, J. (2004) The human L1 promoter: variable transcription initiation sites and a major impact of upstream flanking sequence on promoter activity. Genome Res., 14, 2253-2260.
-
(2004)
Genome Res
, vol.14
, pp. 2253-2260
-
-
Lavie, L.1
Maldener, E.2
Brouha, B.3
Meese, E.4
Mayer, J.5
-
49
-
-
79951499884
-
Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)
-
Beltran, A.S. and Blancafort, P. (2011) Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs). Epigenetics, 6, 224-235.
-
(2011)
Epigenetics
, vol.6
, pp. 224-235
-
-
Beltran, A.S.1
Blancafort, P.2
-
50
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams, K., Christensen, J., Pedersen, M.T., Johansen, J.V., Cloos, P.A., Rappsilber, J. and Helin, K. (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature, 473, 343-348.
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
Helin, K.7
-
51
-
-
84875218124
-
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
-
Deplus, R., Delatte, B., Schwinn, M.K., Defrance, M., Mendez, J., Murphy, N., Dawson, M.A., Volkmar, M., Putmans, P., Calonne, E. et al. (2013) TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J., 32, 645-655.
-
(2013)
EMBO J
, vol.32
, pp. 645-655
-
-
Deplus, R.1
Delatte, B.2
Schwinn, M.K.3
Defrance, M.4
Mendez, J.5
Murphy, N.6
Dawson, M.A.7
Volkmar, M.8
Putmans, P.9
Calonne, E.10
-
52
-
-
84872953223
-
TET2 promotes histone O-GlcNAcylation during gene transcription
-
Chen, Q., Chen, Y., Bian, C., Fujiki, R. and Yu, X. (2013) TET2 promotes histone O-GlcNAcylation during gene transcription. Nature, 493, 561-564.
-
(2013)
Nature
, vol.493
, pp. 561-564
-
-
Chen, Q.1
Chen, Y.2
Bian, C.3
Fujiki, R.4
Yu, X.5
-
53
-
-
84355161950
-
GlcNAcylation of histone H2B facilitates its monoubiquitination
-
Fujiki, R., Hashiba, W., Sekine, H., Yokoyama, A., Chikanishi, T., Ito, S., Imai, Y., Kim, J., He, H.H., Igarashi, K. et al. (2011) GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature, 480, 557-560.
-
(2011)
Nature
, vol.480
, pp. 557-560
-
-
Fujiki, R.1
Hashiba, W.2
Sekine, H.3
Yokoyama, A.4
Chikanishi, T.5
Ito, S.6
Imai, Y.7
Kim, J.8
He, H.H.9
Igarashi, K.10
-
54
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco, M.R., Ficz, G. and Reik, W. (2011) Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat. Rev. Genet., 13, 7-13.
-
(2011)
Nat. Rev. Genet
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
55
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal, K., Jin, S.G., Pfeifer, G.P. and Szabo, P.E. (2011) Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl Acad. Sci. USA, 108, 3642-3647.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
56
-
-
0033960560
-
Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct: Possible in vivo relevance during tumorigenesis
-
Pogribny, I.P., Pogribna, M., Christman, J.K. and James, S.J. (2000) Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct: Possible in vivo relevance during tumorigenesis. Cancer Res., 60, 588-594.
-
(2000)
Cancer Res
, vol.60
, pp. 588-594
-
-
Pogribny, I.P.1
Pogribna, M.2
Christman, J.K.3
James, S.J.4
-
58
-
-
79960123564
-
Epigenetics in disease: Leader or follower?
-
Martin, D.I., Cropley, J.E. and Suter, C.M. (2011) Epigenetics in disease: leader or follower? Epigenetics, 6, 843-848.
-
(2011)
Epigenetics
, vol.6
, pp. 843-848
-
-
Martin, D.I.1
Cropley, J.E.2
Suter, C.M.3
-
59
-
-
41649115210
-
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
-
Kleinman, M.E., Yamada, K., Takeda, A., Chandrasekaran, V., Nozaki, M., Baffi, J.Z., Albuquerque, R.J., Yamasaki, S., Itaya, M., Pan, Y. et al. (2008) Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature, 452, 591-597.
-
(2008)
Nature
, vol.452
, pp. 591-597
-
-
Kleinman, M.E.1
Yamada, K.2
Takeda, A.3
Chandrasekaran, V.4
Nozaki, M.5
Baffi, J.Z.6
Albuquerque, R.J.7
Yamasaki, S.8
Itaya, M.9
Pan, Y.10
-
60
-
-
82055208159
-
-
Olejniczak, M., Polak, K., Galka-Marciniak, P. and Krzyzosiak, W.J. (2011) Recent advances in understanding of the immunological off-target effects of siRNA. Curr. Gene Ther., 11, 532-543.
-
(2011)
Recent Advances in Understanding of the Immunological Off-target Effects of SiRNA. Curr. Gene Ther
, vol.11
, pp. 532-543
-
-
Olejniczak, M.1
Polak, K.2
Galka-Marciniak, P.3
Krzyzosiak, W.J.4
-
61
-
-
79251567720
-
DNA methylation of the first exon is tightly linked to transcriptional silencing
-
Brenet, F., Moh, M., Funk, P., Feierstein, E., Viale, A.J., Socci, N.D. and Scandura, J.M. (2011) DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS One, 6, e14524.
-
(2011)
PLoS One
, vol.6
-
-
Brenet, F.1
Moh, M.2
Funk, P.3
Feierstein, E.4
Viale, A.J.5
Socci, N.D.6
Scandura, J.M.7
-
62
-
-
84863986133
-
Functions of DNA methylation: Islands, start sites, gene bodies and beyond
-
Jones, P.A. (2012) Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet., 13, 484-492.
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
63
-
-
84857742284
-
DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory
-
Raynal, N.J., Si, J., Taby, R.F., Gharibyan, V., Ahmed, S., Jelinek, J., Estecio, M.R. and Issa, J.P. (2012) DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory. Cancer Res., 72, 1170-1181.
-
(2012)
Cancer Res
, vol.72
, pp. 1170-1181
-
-
Raynal, N.J.1
Si, J.2
Taby, R.F.3
Gharibyan, V.4
Ahmed, S.5
Jelinek, J.6
Estecio, M.R.7
Issa, J.P.8
-
64
-
-
33646471380
-
DNA methylation supports intrinsic epigenetic memory in mammalian cells
-
Feng, Y.Q., Desprat, R., Fu, H., Olivier, E., Lin, C.M., Lobell, A., Gowda, S.N., Aladjem, M.I. and Bouhassira, E.E. (2006) DNA methylation supports intrinsic epigenetic memory in mammalian cells. PLoS Genet., 2, e65.
-
(2006)
PLoS Genet
, vol.2
-
-
Feng, Y.Q.1
Desprat, R.2
Fu, H.3
Olivier, E.4
Lin, C.M.5
Lobell, A.6
Gowda, S.N.7
Aladjem, M.I.8
Bouhassira, E.E.9
-
65
-
-
84860589110
-
Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain
-
Gregory, D.J., Mikhaylova, L. and Fedulov, A.V. (2012) Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain. Epigenetics, 7, 344-349.
-
(2012)
Epigenetics
, vol.7
, pp. 344-349
-
-
Gregory, D.J.1
Mikhaylova, L.2
Fedulov, A.V.3
-
66
-
-
0034625141
-
5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex
-
Zhu, B., Zheng, Y., Hess, D., Angliker, H., Schwarz, S., Siegmann, M., Thiry, S. and Jost, J.P. (2000) 5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex. Proc. Natl Acad. Sci. USA, 97, 5135-5139.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 5135-5139
-
-
Zhu, B.1
Zheng, Y.2
Hess, D.3
Angliker, H.4
Schwarz, S.5
Siegmann, M.6
Thiry, S.7
Jost, J.P.8
-
67
-
-
84864922025
-
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
-
Stolzenburg, S., Rots, M.G., Beltran, A.S., Rivenbark, A.G., Yuan, X., Qian, H., Strahl, B.D. and Blancafort, P. (2012) Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer. Nucleic Acids Res., 40, 6725-6740.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 6725-6740
-
-
Stolzenburg, S.1
Rots, M.G.2
Beltran, A.S.3
Rivenbark, A.G.4
Yuan, X.5
Qian, H.6
Strahl, B.D.7
Blancafort, P.8
-
68
-
-
84884475055
-
Towards sustained silencing of Her2/neu in cancer by epigenetic editing
-
Falahi, F., Huisman, C., Kazemier, H.G., Kok, K., Hospers, G.A.P. and Rots, M.G. (2013) Towards sustained silencing of Her2/neu in cancer by epigenetic editing. Mol. Cancer Res., 11, 1029-1039.
-
(2013)
Mol. Cancer Res
, vol.11
, pp. 1029-1039
-
-
Falahi, F.1
Huisman, C.2
Kazemier, H.G.3
Kok, K.4
Hospers, G.A.P.5
Rots, M.G.6
-
69
-
-
84860561774
-
Epigenetic reprogramming of cancer cells via targeted DNA methylation
-
Rivenbark, A.G., Stolzenburg, S., Beltran, A.S., Yuan, X., Rots, M.G., Strahl, B.D. and Blancafort, P. (2012) Epigenetic reprogramming of cancer cells via targeted DNA methylation. Epigenetics, 7, 350-360.
-
(2012)
Epigenetics
, vol.7
, pp. 350-360
-
-
Rivenbark, A.G.1
Stolzenburg, S.2
Beltran, A.S.3
Yuan, X.4
Rots, M.G.5
Strahl, B.D.6
Blancafort, P.7
-
70
-
-
84872865881
-
Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity
-
Siddique, A.N., Nunna, S., Rajavelu, A., Zhang, Y., Jurkowska, R.Z., Reinhardt, R., Rots, M.G., Ragozin, S., Jurkowski, T.P. and Jeltsch, A. (2013) Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity. J. Mol. Biol., 425, 479-491.
-
(2013)
J. Mol. Biol
, vol.425
, pp. 479-491
-
-
Siddique, A.N.1
Nunna, S.2
Rajavelu, A.3
Zhang, Y.4
Jurkowska, R.Z.5
Reinhardt, R.6
Rots, M.G.7
Ragozin, S.8
Jurkowski, T.P.9
Jeltsch, A.10
-
71
-
-
77954879338
-
Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule
-
van der Gun, B.T.F., Maluszynska-Hoffman, M., Kiss, A., Arendzen, A.J., Ruiters, M.H., McLaughlin, P.M., Weinhold, E. and Rots, M.G. (2010) Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule. Bioconjug. Chem., 21, 1239-1245.
-
(2010)
Bioconjug. Chem
, vol.21
, pp. 1239-1245
-
-
Van Der Gun, B.T.F.1
Maluszynska-Hoffman, M.2
Kiss, A.3
Arendzen, A.J.4
Ruiters, M.H.5
McLaughlin, P.M.6
Weinhold, E.7
Rots, M.G.8
-
72
-
-
84859436791
-
Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes
-
Pandian, G.N., Ohtsuki, A., Bando, T., Sato, S., Hashiya, K. and Sugiyama, H. (2012) Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes. Bioorg. Med. Chem., 20, 2656-2660.
-
(2012)
Bioorg. Med. Chem
, vol.20
, pp. 2656-2660
-
-
Pandian, G.N.1
Ohtsuki, A.2
Bando, T.3
Sato, S.4
Hashiya, K.5
Sugiyama, H.6
-
73
-
-
84861556683
-
Complementation between inactive fragments of SssI DNA methyltransferase
-
Slaska, K.K., Timar, E. and Kiss, A. (2012) Complementation between inactive fragments of SssI DNA methyltransferase. BMC Mol. Biol., 13, 13-17.
-
(2012)
BMC Mol. Biol
, vol.13
, pp. 13-17
-
-
Slaska, K.K.1
Timar, E.2
Kiss, A.3
|