-
1
-
-
84904413140
-
The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease
-
Doring Y, Pawig L, Weber C, Noels H. The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. Front Physiol (2014) 5:212. doi:10.3389/fphys.2014.00212.
-
(2014)
Front Physiol
, vol.5
, pp. 212
-
-
Doring, Y.1
Pawig, L.2
Weber, C.3
Noels, H.4
-
2
-
-
84883198880
-
Small molecule inhibitors of CXCR4
-
Debnath B, Xu S, Grande F, Garofalo A, Neamati N. Small molecule inhibitors of CXCR4. Theranostics (2013) 3:47-75. doi:10.7150/thno.5376.
-
(2013)
Theranostics
, vol.3
, pp. 47-75
-
-
Debnath, B.1
Xu, S.2
Grande, F.3
Garofalo, A.4
Neamati, N.5
-
3
-
-
84871412842
-
A review on CXCR4/CXCL12 axis in oncology: no place to hide
-
Domanska UM, Kruizinga RC, Nagengast WB, Timmer-Bosscha H, Huls G, De Vries EG, et al. A review on CXCR4/CXCL12 axis in oncology: no place to hide. Eur J Cancer (2013) 49:219-30. doi:10.1016/j.ejca.2012.05.005.
-
(2013)
Eur J Cancer
, vol.49
, pp. 219-230
-
-
Domanska, U.M.1
Kruizinga, R.C.2
Nagengast, W.B.3
Timmer-Bosscha, H.4
Huls, G.5
De Vries, E.G.6
-
4
-
-
34249066942
-
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
-
Bernhagen J, Krohn R, Lue H, Gregory JL, Zernecke A, Koenen RR, et al. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med (2007) 13:587-96. doi:10.1038/nm1567.
-
(2007)
Nat Med
, vol.13
, pp. 587-596
-
-
Bernhagen, J.1
Krohn, R.2
Lue, H.3
Gregory, J.L.4
Zernecke, A.5
Koenen, R.R.6
-
5
-
-
80052987287
-
The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1 function through distinct receptor interactions
-
Saini V, Staren DM, Ziarek JJ, Nashaat ZN, Campbell EM, Volkman BF, et al. The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1 function through distinct receptor interactions. J Biol Chem (2011) 286:33466-77. doi:10.1074/jbc. M111.233742.
-
(2011)
J Biol Chem
, vol.286
, pp. 33466-33477
-
-
Saini, V.1
Staren, D.M.2
Ziarek, J.J.3
Nashaat, Z.N.4
Campbell, E.M.5
Volkman, B.F.6
-
6
-
-
27444443142
-
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
-
Balabanian K, Lagane B, Infantino S, Chow KY, Harriague J, Moepps B, et al. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem (2005) 280:35760-6. doi:10.1074/jbc. M508234200.
-
(2005)
J Biol Chem
, vol.280
, pp. 35760-35766
-
-
Balabanian, K.1
Lagane, B.2
Infantino, S.3
Chow, K.Y.4
Harriague, J.5
Moepps, B.6
-
7
-
-
78649652845
-
Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts
-
Tarnowski M, Grymula K, Liu R, Tarnowska J, Drukala J, Ratajczak J, et al. Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts. Mol Cancer Res (2010) 8:1328-43. doi:10.1158/1541-7786.MCR-10-0288.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1328-1343
-
-
Tarnowski, M.1
Grymula, K.2
Liu, R.3
Tarnowska, J.4
Drukala, J.5
Ratajczak, J.6
-
8
-
-
33745851881
-
Cutting edge: human beta defensin 3-a novel antagonist of the HIV-1 coreceptor CXCR4
-
Feng Z, Dubyak GR, Lederman MM, Weinberg A. Cutting edge: human beta defensin 3-a novel antagonist of the HIV-1 coreceptor CXCR4. J Immunol (2006) 177:782-6. doi:10.4049/jimmunol.177.2.782.
-
(2006)
J Immunol
, vol.177
, pp. 782-786
-
-
Feng, Z.1
Dubyak, G.R.2
Lederman, M.M.3
Weinberg, A.4
-
9
-
-
0034062515
-
Inhibition of HIV infection by bicyclams, highly potent and specific CXCR4 antagonists
-
De Clercq E. Inhibition of HIV infection by bicyclams, highly potent and specific CXCR4 antagonists. Mol Pharmacol (2000) 57:833-9.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 833-839
-
-
De Clercq, E.1
-
10
-
-
15144349979
-
A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus
-
Kledal TN, Rosenkilde MM, Coulin F, Simmons G, Johnsen AH, Alouani S, et al. A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science (1997) 277:1656-9. doi:10.1126/science.277.5332.1656.
-
(1997)
Science
, vol.277
, pp. 1656-1659
-
-
Kledal, T.N.1
Rosenkilde, M.M.2
Coulin, F.3
Simmons, G.4
Johnsen, A.H.5
Alouani, S.6
-
11
-
-
84924565531
-
Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine
-
Qin L, Kufareva I, Holden LG, Wang C, Zheng Y, Zhao C, et al. Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science (2015) 347:1117-22. doi:10.1126/science.1261064.
-
(2015)
Science
, vol.347
, pp. 1117-1122
-
-
Qin, L.1
Kufareva, I.2
Holden, L.G.3
Wang, C.4
Zheng, Y.5
Zhao, C.6
-
12
-
-
84887512970
-
International union of basic and clinical pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors
-
Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, et al. International union of basic and clinical pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2014) 66:1-79. doi:10.1111/bph.12665.
-
(2014)
Pharmacol Rev
, vol.66
, pp. 1-79
-
-
Bachelerie, F.1
Ben-Baruch, A.2
Burkhardt, A.M.3
Combadiere, C.4
Farber, J.M.5
Graham, G.J.6
-
13
-
-
0032540493
-
Genomic organization and promoter characterization of human CXCR4 gene 1
-
Caruz A, Samsom M, Alonso JM, Alcami J, Baleux F, Virelizier JL, et al. Genomic organization and promoter characterization of human CXCR4 gene 1. FEBS Lett (1998) 426:271-8. doi:10.1016/S0014-5793(98)00359-7.
-
(1998)
FEBS Lett
, vol.426
, pp. 271-278
-
-
Caruz, A.1
Samsom, M.2
Alonso, J.M.3
Alcami, J.4
Baleux, F.5
Virelizier, J.L.6
-
14
-
-
0028012561
-
Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes
-
Loetscher M, Geiser T, O'reilly T, Zwahlen R, Baggiolini M, Moser B. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem (1994) 269:232-7.
-
(1994)
J Biol Chem
, vol.269
, pp. 232-237
-
-
Loetscher, M.1
Geiser, T.2
O'reilly, T.3
Zwahlen, R.4
Baggiolini, M.5
Moser, B.6
-
15
-
-
0030002637
-
HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng Y, Broder CC, Kennedy PE, Berger EA. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science (1996) 272:872-7. doi:10.1126/science.272.5263.872.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
16
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, et al. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature (1996) 382:833-5. doi:10.1038/382833a0.
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.L.5
Arenzana-Seisdedos, F.6
-
17
-
-
0034080318
-
The biology of chemokines and their receptors
-
Rossi D, Zlotnik A. The biology of chemokines and their receptors. Annu Rev Immunol (2000) 18:217-42. doi:10.1146/annurev.immunol.18.1.217.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 217-242
-
-
Rossi, D.1
Zlotnik, A.2
-
18
-
-
33750929921
-
Structural basis of chemokine receptor function-a model for binding affinity and ligand selectivity
-
Rajagopalan L, Rajarathnam K. Structural basis of chemokine receptor function-a model for binding affinity and ligand selectivity. Biosci Rep (2006) 26:325-39. doi:10.1007/s10540-006-9025-9.
-
(2006)
Biosci Rep
, vol.26
, pp. 325-339
-
-
Rajagopalan, L.1
Rajarathnam, K.2
-
19
-
-
84883817684
-
Arrest functions of the MIF ligand/receptor axes in atherogenesis
-
Tillmann S, Bernhagen J, Noels H. Arrest functions of the MIF ligand/receptor axes in atherogenesis. Front Immunol (2013) 4:115. doi:10.3389/fimmu.2013.00115.
-
(2013)
Front Immunol
, vol.4
, pp. 115
-
-
Tillmann, S.1
Bernhagen, J.2
Noels, H.3
-
20
-
-
79952107293
-
Atypical chemokine receptors
-
Ulvmar MH, Hub E, Rot A. Atypical chemokine receptors. Exp Cell Res (2011) 317:556-68. doi:10.1016/j.yexcr.2011.01.012.
-
(2011)
Exp Cell Res
, vol.317
, pp. 556-568
-
-
Ulvmar, M.H.1
Hub, E.2
Rot, A.3
-
21
-
-
57849112701
-
The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity
-
Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, et al. The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. Nat Immunol (2009) 10:101-8. doi:10.1038/ni.1675.
-
(2009)
Nat Immunol
, vol.10
, pp. 101-108
-
-
Pruenster, M.1
Mudde, L.2
Bombosi, P.3
Dimitrova, S.4
Zsak, M.5
Middleton, J.6
-
22
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 25:3389-402. doi:10.1093/nar/25.17.3389.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
-
23
-
-
84883162884
-
Involvement of CXCR4/CXCR7/CXCL12 Interactions in Inflammatory bowel disease
-
Werner L, Guzner-Gur H, Dotan I. Involvement of CXCR4/CXCR7/CXCL12 Interactions in Inflammatory bowel disease. Theranostics (2013) 3:40-6. doi:10.7150/thno.5135.
-
(2013)
Theranostics
, vol.3
, pp. 40-46
-
-
Werner, L.1
Guzner-Gur, H.2
Dotan, I.3
-
24
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
Wu B, Chien EYT, Mol CD, Fenalti G, Liu W, Katritch V, et al. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (2010) 330:1066-71. doi:10.1126/science.1194396.
-
(2010)
Science
, vol.330
, pp. 1066-1071
-
-
Wu, B.1
Chien, E.Y.T.2
Mol, C.D.3
Fenalti, G.4
Liu, W.5
Katritch, V.6
-
25
-
-
84919360392
-
Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation
-
Kufareva I, Stephens BS, Holden LG, Qin L, Zhao C, Kawamura T, et al. Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation. Proc Natl Acad Sci U S A (2014) 111:5363-72. doi:10.1073/pnas.1417037111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 5363-5372
-
-
Kufareva, I.1
Stephens, B.S.2
Holden, L.G.3
Qin, L.4
Zhao, C.5
Kawamura, T.6
-
26
-
-
77951245615
-
Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family
-
Murphy JW, Yuan H, Kong Y, Xiong Y, Lolis EJ. Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family. Proteins (2010) 78:1331-7. doi:10.1002/prot.22666.
-
(2010)
Proteins
, vol.78
, pp. 1331-1337
-
-
Murphy, J.W.1
Yuan, H.2
Kong, Y.3
Xiong, Y.4
Lolis, E.J.5
-
27
-
-
58549105131
-
Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions
-
Crichlow GV, Lubetsky JB, Leng L, Bucala R, Lolis EJ. Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry (2009) 48:132-9. doi:10.1021/bi8014423.
-
(2009)
Biochemistry
, vol.48
, pp. 132-139
-
-
Crichlow, G.V.1
Lubetsky, J.B.2
Leng, L.3
Bucala, R.4
Lolis, E.J.5
-
28
-
-
0035824563
-
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting
-
Marchese A, Benovic JL. Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. J Biol Chem (2001) 276:45509-12. doi:10.1074/jbc. C100527200.
-
(2001)
J Biol Chem
, vol.276
, pp. 45509-45512
-
-
Marchese, A.1
Benovic, J.L.2
-
29
-
-
0029099521
-
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene
-
Shirozu M, Nakano T, Inazawa J, Tashiro K, Tada H, Shinohara T, et al. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics (1995) 28:495-500. doi:10.1006/geno.1995.1180.
-
(1995)
Genomics
, vol.28
, pp. 495-500
-
-
Shirozu, M.1
Nakano, T.2
Inazawa, J.3
Tashiro, K.4
Tada, H.5
Shinohara, T.6
-
30
-
-
33646749900
-
Identification and expression of novel isoforms of human stromal cell-derived factor 1
-
Yu L, Cecil J, Peng S-B, Schrementi J, Kovacevic S, Paul D, et al. Identification and expression of novel isoforms of human stromal cell-derived factor 1. Gene (2006) 374:174-9. doi:10.1016/j.gene.2006.02.001.
-
(2006)
Gene
, vol.374
, pp. 174-179
-
-
Yu, L.1
Cecil, J.2
Peng, S.-B.3
Schrementi, J.4
Kovacevic, S.5
Paul, D.6
-
31
-
-
49749117434
-
The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins
-
Rueda P, Balabanian K, Lagane B, Staropoli I, Chow K, Levoye A, et al. The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins. PLoS One (2008) 3:e2543. doi:10.1371/journal.pone.0002543.
-
(2008)
PLoS One
, vol.3
-
-
Rueda, P.1
Balabanian, K.2
Lagane, B.3
Staropoli, I.4
Chow, K.5
Levoye, A.6
-
32
-
-
42549130865
-
The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4
-
Laguri C, Sadir R, Rueda P, Baleux F, Gans P, Arenzana-Seisdedos F, et al. The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4. PLoS One (2007) 2:e1110. doi:10.1371/journal.pone.0001110.
-
(2007)
PLoS One
, vol.2
-
-
Laguri, C.1
Sadir, R.2
Rueda, P.3
Baleux, F.4
Gans, P.5
Arenzana-Seisdedos, F.6
-
33
-
-
77949314287
-
A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart
-
Torres R, Ramirez JC. A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart. PLoS One (2009) 4:e7570. doi:10.1371/journal.pone.0007570.
-
(2009)
PLoS One
, vol.4
-
-
Torres, R.1
Ramirez, J.C.2
-
34
-
-
0037101610
-
A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia
-
Stumm RK, Rummel J, Junker V, Culmsee C, Pfeiffer M, Krieglstein J, et al. A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J Neurosci (2002) 22:5865-78.
-
(2002)
J Neurosci
, vol.22
, pp. 5865-5878
-
-
Stumm, R.K.1
Rummel, J.2
Junker, V.3
Culmsee, C.4
Pfeiffer, M.5
Krieglstein, J.6
-
35
-
-
24644519490
-
The transcriptional landscape of the mammalian genome
-
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, et al. The transcriptional landscape of the mammalian genome. Science (2005) 309:1559-63. doi:10.1126/science.1112014.
-
(2005)
Science
, vol.309
, pp. 1559-1563
-
-
Carninci, P.1
Kasukawa, T.2
Katayama, S.3
Gough, J.4
Frith, M.C.5
Maeda, N.6
-
36
-
-
0030683638
-
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1
-
Crump MP, Gong JH, Loetscher P, Rajarathnam K, Amara A, Arenzana-Seisdedos F, et al. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J (1997) 16:6996-7007. doi:10.1093/emboj/16.23.6996.
-
(1997)
EMBO J
, vol.16
, pp. 6996-7007
-
-
Crump, M.P.1
Gong, J.H.2
Loetscher, P.3
Rajarathnam, K.4
Amara, A.5
Arenzana-Seisdedos, F.6
-
37
-
-
0030065093
-
Selectivity and antagonism of chemokine receptors
-
Wells TN, Power CA, Lusti-Narasimhan M, Hoogewerf AJ, Cooke RM, Chung CW, et al. Selectivity and antagonism of chemokine receptors. J Leukoc Biol (1996) 59:53-60.
-
(1996)
J Leukoc Biol
, vol.59
, pp. 53-60
-
-
Wells, T.N.1
Power, C.A.2
Lusti-Narasimhan, M.3
Hoogewerf, A.J.4
Cooke, R.M.5
Chung, C.W.6
-
38
-
-
54849422396
-
Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases
-
Seibert C, Veldkamp CT, Peterson FC, Chait BT, Volkman BF, Sakmar TP. Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases. Biochemistry (2008) 47:11251-62. doi:10.1021/bi800965m.
-
(2008)
Biochemistry
, vol.47
, pp. 11251-11262
-
-
Seibert, C.1
Veldkamp, C.T.2
Peterson, F.C.3
Chait, B.T.4
Volkman, B.F.5
Sakmar, T.P.6
-
39
-
-
54849434087
-
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
-
Veldkamp CT, Seibert C, Peterson FC, De La Cruz NB, Haugner JC III, Basnet H, et al. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal (2008) 1:ra4. doi:10.1126/scisignal.1160755.
-
(2008)
Sci Signal
, vol.1
-
-
Veldkamp, C.T.1
Seibert, C.2
Peterson, F.C.3
De La Cruz, N.B.4
Haugner, J.C.5
Basnet, H.6
-
40
-
-
84905637489
-
Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells
-
Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, et al. Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev (2014) 23:1959-74. doi:10.1089/scd.2013.0524.
-
(2014)
Stem Cells Dev
, vol.23
, pp. 1959-1974
-
-
Richter, R.1
Jochheim-Richter, A.2
Ciuculescu, F.3
Kollar, K.4
Seifried, E.5
Forssmann, U.6
-
41
-
-
0035839639
-
Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family
-
Lambeir AM, Proost P, Durinx C, Bal G, Senten K, Augustyns K, et al. Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family. J Biol Chem (2001) 276:29839-45. doi:10.1074/jbc. M103106200.
-
(2001)
J Biol Chem
, vol.276
, pp. 29839-29845
-
-
Lambeir, A.M.1
Proost, P.2
Durinx, C.3
Bal, G.4
Senten, K.5
Augustyns, K.6
-
42
-
-
70350528813
-
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12
-
O'boyle G, Mellor P, Kirby JA, Ali S. Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12. FASEB J (2009) 23:3906-16. doi:10.1096/fj.09-134643.
-
(2009)
FASEB J
, vol.23
, pp. 3906-3916
-
-
O'boyle, G.1
Mellor, P.2
Kirby, J.A.3
Ali, S.4
-
43
-
-
13144283654
-
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
-
Shioda T, Kato H, Ohnishi Y, Tashiro K, Ikegawa M, Nakayama EE, et al. Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage. Proc Natl Acad Sci U S A (1998) 95:6331-6. doi:10.1073/pnas.95.11.6331.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6331-6336
-
-
Shioda, T.1
Kato, H.2
Ohnishi, Y.3
Tashiro, K.4
Ikegawa, M.5
Nakayama, E.E.6
-
44
-
-
1642366238
-
Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity
-
De La Luz Sierra M, Yang F, Narazaki M, Salvucci O, Davis D, Yarchoan R, et al. Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity. Blood (2004) 103:2452-9. doi:10.1182/blood-2003-08-2857.
-
(2004)
Blood
, vol.103
, pp. 2452-2459
-
-
De La Luz Sierra, M.1
Yang, F.2
Narazaki, M.3
Salvucci, O.4
Davis, D.5
Yarchoan, R.6
-
45
-
-
0035379704
-
Comodulation of CXCR4 and CD26 in human lymphocytes
-
Herrera C, Morimoto C, Blanco J, Mallol J, Arenzana F, Lluis C, et al. Comodulation of CXCR4 and CD26 in human lymphocytes. J Biol Chem (2001) 276:19532-9. doi:10.1074/jbc. M004586200.
-
(2001)
J Biol Chem
, vol.276
, pp. 19532-19539
-
-
Herrera, C.1
Morimoto, C.2
Blanco, J.3
Mallol, J.4
Arenzana, F.5
Lluis, C.6
-
46
-
-
84869005246
-
Proteolytic processing of SDF-1a by matrix metalloproteinase-2 impairs CXCR4 signaling and reduces neural progenitor cell migration
-
Peng H, Wu Y, Duan Z, Ciborowski P, Zheng J. Proteolytic processing of SDF-1a by matrix metalloproteinase-2 impairs CXCR4 signaling and reduces neural progenitor cell migration. Protein Cell (2012) 3:875-82. doi:10.1007/s13238-012-2092-8.
-
(2012)
Protein Cell
, vol.3
, pp. 875-882
-
-
Peng, H.1
Wu, Y.2
Duan, Z.3
Ciborowski, P.4
Zheng, J.5
-
47
-
-
0035941359
-
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
-
McQuibban GA, Butler GS, Gong J-H, Bendall L, Power C, Clark-Lewis I, et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem (2001) 276:43503-8. doi:10.1074/jbc. M107736200.
-
(2001)
J Biol Chem
, vol.276
, pp. 43503-43508
-
-
McQuibban, G.A.1
Butler, G.S.2
Gong, J.-H.3
Bendall, L.4
Power, C.5
Clark-Lewis, I.6
-
48
-
-
0037013221
-
Leukocyte elastase negatively regulates stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4
-
Valenzuela-Fernández AN, Planchenault T, Baleux F, Staropoli I, Le-Barillec K, Leduc D, et al. Leukocyte elastase negatively regulates stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem (2002) 277:15677-89. doi:10.1074/jbc. M111388200.
-
(2002)
J Biol Chem
, vol.277
, pp. 15677-15689
-
-
Valenzuela-Fernández, A.N.1
Planchenault, T.2
Baleux, F.3
Staropoli, I.4
Le-Barillec, K.5
Leduc, D.6
-
49
-
-
0035079801
-
Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes
-
Delgado MB, Clark-Lewis I, Loetscher P, Langen H, Thelen M, Baggiolini M, et al. Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes. Eur J Immunol (2001) 31:699-707. doi:10.1002/1521-4141(200103)31:3<699::AID-IMMU699>3.0.CO;2-6.
-
(2001)
Eur J Immunol
, vol.31
, pp. 699-707
-
-
Delgado, M.B.1
Clark-Lewis, I.2
Loetscher, P.3
Langen, H.4
Thelen, M.5
Baggiolini, M.6
-
50
-
-
0033588220
-
Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine
-
Amara A, Lorthioir O, Valenzuela A, Magerus A, Thelen M, Montes M, et al. Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine. J Biol Chem (1999) 274:23916-25. doi:10.1074/jbc.274.34.23916.
-
(1999)
J Biol Chem
, vol.274
, pp. 23916-23925
-
-
Amara, A.1
Lorthioir, O.2
Valenzuela, A.3
Magerus, A.4
Thelen, M.5
Montes, M.6
-
51
-
-
84867255818
-
Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions
-
Rueda P, Richart A, Recalde A, Gasse P, Vilar J, Guerin C, et al. Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions. Circulation (2012) 126:1882-95. doi:10.1161/CIRCULATIONAHA.112.113290.
-
(2012)
Circulation
, vol.126
, pp. 1882-1895
-
-
Rueda, P.1
Richart, A.2
Recalde, A.3
Gasse, P.4
Vilar, J.5
Guerin, C.6
-
52
-
-
0142259734
-
Macrophage migration inhibitory factor: a regulator of innate immunity
-
Calandra T, Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol (2003) 3:791-800. doi:10.1038/nri1200.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 791-800
-
-
Calandra, T.1
Roger, T.2
-
53
-
-
0029895838
-
Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor
-
Sun HW, Bernhagen J, Bucala R, Lolis E. Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor. Proc Natl Acad Sci U S A (1996) 93:5191-6. doi:10.1073/pnas.93.11.5191.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5191-5196
-
-
Sun, H.W.1
Bernhagen, J.2
Bucala, R.3
Lolis, E.4
-
54
-
-
0032080006
-
Cross-linking and mutational analysis of the oligomerization state of the cytokine macrophage migration inhibitory factor (MIF)
-
Mischke R, Kleemann R, Brunner H, Bernhagen J. Cross-linking and mutational analysis of the oligomerization state of the cytokine macrophage migration inhibitory factor (MIF). FEBS Lett (1998) 427:85-90. doi:10.1016/S0014-5793(98)00400-1.
-
(1998)
FEBS Lett
, vol.427
, pp. 85-90
-
-
Mischke, R.1
Kleemann, R.2
Brunner, H.3
Bernhagen, J.4
-
55
-
-
1642384385
-
Re-examining the oligomerization state of macrophage migration inhibitory factor (MIF) in solution
-
Philo JS, Yang TH, Labarre M. Re-examining the oligomerization state of macrophage migration inhibitory factor (MIF) in solution. Biophys Chem (2004) 108:77-87. doi:10.1016/j.bpc.2003.10.010.
-
(2004)
Biophys Chem
, vol.108
, pp. 77-87
-
-
Philo, J.S.1
Yang, T.H.2
Labarre, M.3
-
56
-
-
77956212412
-
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action
-
Ouertatani-Sakouhi H, El-Turk F, Fauvet B, Cho MK, Pinar Karpinar D, Le Roy D, et al. Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. J Biol Chem (2010) 285:26581-98. doi:10.1074/jbc. M110.113951.
-
(2010)
J Biol Chem
, vol.285
, pp. 26581-26598
-
-
Ouertatani-Sakouhi, H.1
El-Turk, F.2
Fauvet, B.3
Cho, M.K.4
Pinar Karpinar, D.5
Le Roy, D.6
-
57
-
-
84930332449
-
Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1
-
Israelson A, Ditsworth D, Sun S, Song S, Liang J, Hruska-Plochan M, et al. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. Neuron (2015) 86:218-32. doi:10.1016/j.neuron.2015.02.034.
-
(2015)
Neuron
, vol.86
, pp. 218-232
-
-
Israelson, A.1
Ditsworth, D.2
Sun, S.3
Song, S.4
Liang, J.5
Hruska-Plochan, M.6
-
58
-
-
84901770846
-
The critical role of macrophage migration inhibitory factor in insulin activity
-
Vujicic M, Senerovic L, Nikolic I, Saksida T, Stosic-Grujicic S, Stojanovic I. The critical role of macrophage migration inhibitory factor in insulin activity. Cytokine (2014) 69:39-46. doi:10.1016/j.cyto.2014.05.013.
-
(2014)
Cytokine
, vol.69
, pp. 39-46
-
-
Vujicic, M.1
Senerovic, L.2
Nikolic, I.3
Saksida, T.4
Stosic-Grujicic, S.5
Stojanovic, I.6
-
59
-
-
0027997701
-
Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF)
-
Bernhagen J, Mitchell RA, Calandra T, Voelter W, Cerami A, Bucala R. Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF). Biochemistry (1994) 33:14144-55. doi:10.1021/bi00251a025.
-
(1994)
Biochemistry
, vol.33
, pp. 14144-14155
-
-
Bernhagen, J.1
Mitchell, R.A.2
Calandra, T.3
Voelter, W.4
Cerami, A.5
Bucala, R.6
-
60
-
-
68549099805
-
Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis
-
Noels H, Bernhagen J, Weber C. Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis. Trends Cardiovasc Med (2009) 19:76-86. doi:10.1016/j.tcm.2009.05.002.
-
(2009)
Trends Cardiovasc Med
, vol.19
, pp. 76-86
-
-
Noels, H.1
Bernhagen, J.2
Weber, C.3
-
61
-
-
55849139457
-
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment
-
Weber C, Kraemer S, Drechsler M, Lue H, Koenen RR, Kapurniotu A, et al. Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proc Natl Acad Sci U S A (2008) 105:16278-83. doi:10.1073/pnas.0804017105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16278-16283
-
-
Weber, C.1
Kraemer, S.2
Drechsler, M.3
Lue, H.4
Koenen, R.R.5
Kapurniotu, A.6
-
62
-
-
79954573511
-
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism
-
Kraemer S, Lue H, Zernecke A, Kapurniotu A, Andreetto E, Frank R, et al. MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J (2011) 25:894-906. doi:10.1096/fj.10-168559.
-
(2011)
FASEB J
, vol.25
, pp. 894-906
-
-
Kraemer, S.1
Lue, H.2
Zernecke, A.3
Kapurniotu, A.4
Andreetto, E.5
Frank, R.6
-
63
-
-
84921822481
-
Exploring the binding mechanisms of MIF to CXCR2 using theoretical approaches
-
Xu L, Li Y, Li D, Xu P, Tian S, Sun H, et al. Exploring the binding mechanisms of MIF to CXCR2 using theoretical approaches. Phys Chem Chem Phys (2015) 17:3370-82. doi:10.1039/c4cp05095a.
-
(2015)
Phys Chem Chem Phys
, vol.17
, pp. 3370-3382
-
-
Xu, L.1
Li, Y.2
Li, D.3
Xu, P.4
Tian, S.5
Sun, H.6
-
64
-
-
24144433455
-
Link between macrophage migration inhibitory factor and cellular redox regulation
-
Thiele M, Bernhagen J. Link between macrophage migration inhibitory factor and cellular redox regulation. Antioxid Redox Signal (2005) 7:1234-48. doi:10.1089/ars.2005.7.1234.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1234-1248
-
-
Thiele, M.1
Bernhagen, J.2
-
65
-
-
33846471122
-
Proteasome-independent functions of ubiquitin in endocytosis and signaling
-
Mukhopadhyay D, Riezman H. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science (2007) 315:201-5. doi:10.1126/science.1127085.
-
(2007)
Science
, vol.315
, pp. 201-205
-
-
Mukhopadhyay, D.1
Riezman, H.2
-
66
-
-
77953715170
-
Regulatory mechanisms involved in the control of ubiquitin homeostasis
-
Kimura Y, Tanaka K. Regulatory mechanisms involved in the control of ubiquitin homeostasis. J Biochem (2010) 147:793-8. doi:10.1093/jb/mvq044.
-
(2010)
J Biochem
, vol.147
, pp. 793-798
-
-
Kimura, Y.1
Tanaka, K.2
-
67
-
-
2942756226
-
The ubiquitin-proteasome pathway
-
Roos-Mattjus P, Sistonen L. The ubiquitin-proteasome pathway. Ann Med (2004) 36:285-95. doi:10.1080/07853890310016324.
-
(2004)
Ann Med
, vol.36
, pp. 285-295
-
-
Roos-Mattjus, P.1
Sistonen, L.2
-
68
-
-
79951843623
-
Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules
-
Majetschak M. Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules. J Leukoc Biol (2011) 89:205-19. doi:10.1189/jlb.0510316.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 205-219
-
-
Majetschak, M.1
-
69
-
-
2442437350
-
Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells
-
Goldstein G, Scheid M, Hammerling U, Schlesinger DH, Niall HD, Boyse EA. Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc Natl Acad Sci U S A (1975) 72:11-5. doi:10.1073/pnas.72.1.11.
-
(1975)
Proc Natl Acad Sci U S A
, vol.72
, pp. 11-15
-
-
Goldstein, G.1
Scheid, M.2
Hammerling, U.3
Schlesinger, D.H.4
Niall, H.D.5
Boyse, E.A.6
-
70
-
-
77952014394
-
CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin
-
Saini V, Marchese A, Majetschak M. CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. J Biol Chem (2010) 285:15566-76. doi:10.1074/jbc. M110.103408.
-
(2010)
J Biol Chem
, vol.285
, pp. 15566-15576
-
-
Saini, V.1
Marchese, A.2
Majetschak, M.3
-
71
-
-
83755162544
-
Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction
-
Saini V, Marchese A, Tang WJ, Majetschak M. Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction. J Biol Chem (2011) 286:44145-52. doi:10.1074/jbc. M111.298505.
-
(2011)
J Biol Chem
, vol.286
, pp. 44145-44152
-
-
Saini, V.1
Marchese, A.2
Tang, W.J.3
Majetschak, M.4
-
72
-
-
0032546844
-
The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens
-
Wyatt R, Sodroski J. The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science (1998) 280:1884-8. doi:10.1126/science.280.5371.1884.
-
(1998)
Science
, vol.280
, pp. 1884-1888
-
-
Wyatt, R.1
Sodroski, J.2
-
73
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature (1998) 393:648-59. doi:10.1038/31405.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
74
-
-
67249086022
-
Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus
-
Simon-Loriere E, Galetto R, Hamoudi M, Archer J, Lefeuvre P, Martin DP, et al. Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus. PLoS Pathog (2009) 5:e1000418. doi:10.1371/journal.ppat.1000418.
-
(2009)
PLoS Pathog
, vol.5
-
-
Simon-Loriere, E.1
Galetto, R.2
Hamoudi, M.3
Archer, J.4
Lefeuvre, P.5
Martin, D.P.6
-
75
-
-
0030962291
-
Atomic structure of the ectodomain from HIV-1 gp41
-
Weissenhorn W, Dessen A, Harrison SC, Skehel JJ, Wiley DC. Atomic structure of the ectodomain from HIV-1 gp41. Nature (1997) 387:426-30. doi:10.1038/387426a0.
-
(1997)
Nature
, vol.387
, pp. 426-430
-
-
Weissenhorn, W.1
Dessen, A.2
Harrison, S.C.3
Skehel, J.J.4
Wiley, D.C.5
-
76
-
-
80051737642
-
HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation
-
Checkley MA, Luttge BG, Freed EO. HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation. J Mol Biol (2011) 410:582-608. doi:10.1016/j.jmb.2011.04.042.
-
(2011)
J Mol Biol
, vol.410
, pp. 582-608
-
-
Checkley, M.A.1
Luttge, B.G.2
Freed, E.O.3
-
77
-
-
0028813111
-
Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure
-
Poumbourios P, El Ahmar W, McPhee DA, Kemp BE. Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure. J Virol (1995) 69:1209-18.
-
(1995)
J Virol
, vol.69
, pp. 1209-1218
-
-
Poumbourios, P.1
El Ahmar, W.2
McPhee, D.A.3
Kemp, B.E.4
-
78
-
-
0026069632
-
Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein
-
Helseth E, Olshevsky U, Furman C, Sodroski J. Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein. J Virol (1991) 65:2119-23.
-
(1991)
J Virol
, vol.65
, pp. 2119-2123
-
-
Helseth, E.1
Olshevsky, U.2
Furman, C.3
Sodroski, J.4
-
80
-
-
0025253819
-
Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
-
Olshevsky U, Helseth E, Furman C, Li J, Haseltine W, Sodroski J. Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding. J Virol (1990) 64:5701-7.
-
(1990)
J Virol
, vol.64
, pp. 5701-5707
-
-
Olshevsky, U.1
Helseth, E.2
Furman, C.3
Li, J.4
Haseltine, W.5
Sodroski, J.6
-
81
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
Liu J, Bartesaghi A, Borgnia MJ, Sapiro G, Subramaniam S. Molecular architecture of native HIV-1 gp120 trimers. Nature (2008) 455:109-13. doi:10.1038/nature07159.
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
83
-
-
0035259780
-
Viral exploitation and subversion of the immune system through chemokine mimicry
-
Murphy PM. Viral exploitation and subversion of the immune system through chemokine mimicry. Nat Immunol (2001) 2:116-22. doi:10.1038/84214.
-
(2001)
Nat Immunol
, vol.2
, pp. 116-122
-
-
Murphy, P.M.1
-
84
-
-
0034603860
-
A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II
-
Zhou N, Luo Z, Luo J, Hall JW, Huang Z. A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II. Biochemistry (2000) 39:3782-7. doi:10.1021/bi992750v.
-
(2000)
Biochemistry
, vol.39
, pp. 3782-3787
-
-
Zhou, N.1
Luo, Z.2
Luo, J.3
Hall, J.W.4
Huang, Z.5
-
85
-
-
84884132303
-
Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases
-
Portella L, Vitale R, De Luca S, D'alterio C, Ierano C, Napolitano M, et al. Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases. PLoS One (2013) 8:e74548. doi:10.1371/journal.pone.0074548.
-
(2013)
PLoS One
, vol.8
-
-
Portella, L.1
Vitale, R.2
De Luca, S.3
D'alterio, C.4
Ierano, C.5
Napolitano, M.6
-
86
-
-
0035937107
-
Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic
-
Harder J, Bartels J, Christophers E, Schroder JM. Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem (2001) 276:5707-13. doi:10.1074/jbc. M008557200.
-
(2001)
J Biol Chem
, vol.276
, pp. 5707-5713
-
-
Harder, J.1
Bartels, J.2
Christophers, E.3
Schroder, J.M.4
-
87
-
-
84879985213
-
Human beta-defensin-3 structure motifs that are important in CXCR4 antagonism
-
Feng Z, Dubyak GR, Jia X, Lubkowski JT, Weinberg A. Human beta-defensin-3 structure motifs that are important in CXCR4 antagonism. FEBS J (2013) 280:3365-75. doi:10.1111/febs.12328.
-
(2013)
FEBS J
, vol.280
, pp. 3365-3375
-
-
Feng, Z.1
Dubyak, G.R.2
Jia, X.3
Lubkowski, J.T.4
Weinberg, A.5
-
88
-
-
0034210221
-
The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice
-
Peled A, Kollet O, Ponomaryov T, Petit I, Franitza S, Grabovsky V, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood (2000) 95:3289-96.
-
(2000)
Blood
, vol.95
, pp. 3289-3296
-
-
Peled, A.1
Kollet, O.2
Ponomaryov, T.3
Petit, I.4
Franitza, S.5
Grabovsky, V.6
-
89
-
-
80053337718
-
Hematopoietic stem and progenitor cell trafficking
-
Mazo IB, Massberg S, Von Andrian UH. Hematopoietic stem and progenitor cell trafficking. Trends Immunol (2011) 32:493-503. doi:10.1016/j.it.2011.06.011.
-
(2011)
Trends Immunol
, vol.32
, pp. 493-503
-
-
Mazo, I.B.1
Massberg, S.2
Von Andrian, U.H.3
-
90
-
-
0037237648
-
Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
-
Levesque JP, Hendy J, Takamatsu Y, Simmons PJ, Bendall LJ. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest (2003) 111:187-96. doi:10.1172/JCI15994.
-
(2003)
J Clin Invest
, vol.111
, pp. 187-196
-
-
Levesque, J.P.1
Hendy, J.2
Takamatsu, Y.3
Simmons, P.J.4
Bendall, L.J.5
-
91
-
-
0034141444
-
Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival
-
Lataillade JJ, Clay D, Dupuy C, Rigal S, Jasmin C, Bourin P, et al. Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood (2000) 95:756-68.
-
(2000)
Blood
, vol.95
, pp. 756-768
-
-
Lataillade, J.J.1
Clay, D.2
Dupuy, C.3
Rigal, S.4
Jasmin, C.5
Bourin, P.6
-
92
-
-
0037097581
-
Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines
-
Lee Y, Gotoh A, Kwon H-J, You M, Kohli L, Mantel C, et al. Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood (2002) 99:4307-17. doi:10.1182/blood. V99.12.4307.
-
(2002)
Blood
, vol.99
, pp. 4307-4317
-
-
Lee, Y.1
Gotoh, A.2
Kwon, H.-J.3
You, M.4
Kohli, L.5
Mantel, C.6
-
93
-
-
77954974268
-
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow
-
Eash KJ, Greenbaum AM, Gopalan PK, Link DC. CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest (2010) 120:2423-31. doi:10.1172/JCI41649.
-
(2010)
J Clin Invest
, vol.120
, pp. 2423-2431
-
-
Eash, K.J.1
Greenbaum, A.M.2
Gopalan, P.K.3
Link, D.C.4
-
94
-
-
84886817890
-
Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow
-
Devi S, Wang Y, Chew WK, Lima R, A-González N, Mattar CN, et al. Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow. J Exp Med (2013) 210:2321-36. doi:10.1084/jem.20130056.
-
(2013)
J Exp Med
, vol.210
, pp. 2321-2336
-
-
Devi, S.1
Wang, Y.2
Chew, W.K.3
Lima, R.4
A.-González, N.5
Mattar, C.N.6
-
95
-
-
0032482926
-
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice
-
Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice. Proc Natl Acad Sci U S A (1998) 95:9448-53. doi:10.1073/pnas.95.16.9448.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9448-9453
-
-
Ma, Q.1
Jones, D.2
Borghesani, P.R.3
Segal, R.A.4
Nagasawa, T.5
Kishimoto, T.6
-
96
-
-
77953090345
-
CXCL12 (SDF-1)/CXCR4 pathway in cancer
-
Teicher BA, Fricker SP. CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res (2010) 16:2927-31. doi:10.1158/1078-0432.CCR-09-2329.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2927-2931
-
-
Teicher, B.A.1
Fricker, S.P.2
-
97
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Kleinman ME, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med (2004) 10:858-64. doi:10.1038/nm1075.
-
(2004)
Nat Med
, vol.10
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
-
98
-
-
44049090880
-
Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction
-
Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, et al. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation (2008) 117:2224-31. doi:10.1161/CIRCULATIONAHA.107.694992.
-
(2008)
Circulation
, vol.117
, pp. 2224-2231
-
-
Saxena, A.1
Fish, J.E.2
White, M.D.3
Yu, S.4
Smyth, J.W.5
Shaw, R.M.6
-
99
-
-
84866757683
-
Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model
-
Schuh A, Kroh A, Konschalla S, Liehn EA, Sobota RM, Biessen EA, et al. Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model. J Cell Mol Med (2012) 16:2311-20. doi:10.1111/j.1582-4934.2012.01539.x.
-
(2012)
J Cell Mol Med
, vol.16
, pp. 2311-2320
-
-
Schuh, A.1
Kroh, A.2
Konschalla, S.3
Liehn, E.A.4
Sobota, R.M.5
Biessen, E.A.6
-
100
-
-
78449291472
-
SDF-1alpha/CXCR4 axis is involved in glucose-potentiated proliferation and chemotaxis in rat vascular smooth muscle cells
-
Jie W, Wang X, Zhang Y, Guo J, Kuang D, Zhu P, et al. SDF-1alpha/CXCR4 axis is involved in glucose-potentiated proliferation and chemotaxis in rat vascular smooth muscle cells. Int J Exp Pathol (2010) 91:436-44. doi:10.1111/j.1365-2613.2010.00720.x.
-
(2010)
Int J Exp Pathol
, vol.91
, pp. 436-444
-
-
Jie, W.1
Wang, X.2
Zhang, Y.3
Guo, J.4
Kuang, D.5
Zhu, P.6
-
101
-
-
84928559720
-
Increased natural killer cell chemotaxis to CXCL12 in patients with multiple sclerosis
-
Serrano-Pertierra E, Blanco-Gelaz MA, Oliva-Nacarino P, Martínez-Camblor P, Villafani J, López-Larrea C, et al. Increased natural killer cell chemotaxis to CXCL12 in patients with multiple sclerosis. J Neuroimmunol (2015) 282:39-44. doi:10.1016/j.jneuroim.2015.03.007.
-
(2015)
J Neuroimmunol
, vol.282
, pp. 39-44
-
-
Serrano-Pertierra, E.1
Blanco-Gelaz, M.A.2
Oliva-Nacarino, P.3
Martínez-Camblor, P.4
Villafani, J.5
López-Larrea, C.6
-
102
-
-
45749105047
-
p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice
-
Olive M, Mellad JA, Beltran LE, Ma M, Cimato T, Noguchi AC, et al. p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice. J Clin Invest (2008) 118:2050-61. doi:10.1172/JCI31244.
-
(2008)
J Clin Invest
, vol.118
, pp. 2050-2061
-
-
Olive, M.1
Mellad, J.A.2
Beltran, L.E.3
Ma, M.4
Cimato, T.5
Noguchi, A.C.6
-
103
-
-
0035063938
-
Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation
-
Mellado M, Rodriguez-Frade JM, Manes S, Martinez-A C. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. Annu Rev Immunol (2001) 19:397-421. doi:10.1146/annurev.immunol.19.1.397.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 397-421
-
-
Mellado, M.1
Rodriguez-Frade, J.M.2
Manes, S.3
Martinez-A, C.4
-
104
-
-
84874510481
-
Stroma cell-derived factor-1a signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes
-
Hadad I, Veithen A, Springael JY, Sotiropoulou PA, Mendes Da Costa A, Miot F, et al. Stroma cell-derived factor-1a signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes. PLoS One (2013) 8:e56007. doi:10.1371/journal.pone.0056007.
-
(2013)
PLoS One
, vol.8
-
-
Hadad, I.1
Veithen, A.2
Springael, J.Y.3
Sotiropoulou, P.A.4
Mendes Da Costa, A.5
Miot, F.6
-
105
-
-
0028970253
-
Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells
-
Myers SJ, Wong LM, Charo IF. Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells. J Biol Chem (1995) 270:5786-92. doi:10.1074/jbc.270.11.5786.
-
(1995)
J Biol Chem
, vol.270
, pp. 5786-5792
-
-
Myers, S.J.1
Wong, L.M.2
Charo, I.F.3
-
106
-
-
84883171439
-
The role of chemokine receptor CXCR4 in breast cancer metastasis
-
Mukherjee D, Zhao J. The role of chemokine receptor CXCR4 in breast cancer metastasis. Am J Cancer Res (2013) 3:46-57.
-
(2013)
Am J Cancer Res
, vol.3
, pp. 46-57
-
-
Mukherjee, D.1
Zhao, J.2
-
107
-
-
0031984517
-
The many faces of G protein signaling
-
Hamm HE. The many faces of G protein signaling. J Biol Chem (1998) 273:669-72. doi:10.1074/jbc.273.2.669.
-
(1998)
J Biol Chem
, vol.273
, pp. 669-672
-
-
Hamm, H.E.1
-
108
-
-
34248587328
-
G Protein regulation of MAPK networks
-
Goldsmith ZG, Dhanasekaran DN. G Protein regulation of MAPK networks. Oncogene (2007) 26:3122-42. doi:10.1038/sj.onc.1210407.
-
(2007)
Oncogene
, vol.26
, pp. 3122-3142
-
-
Goldsmith, Z.G.1
Dhanasekaran, D.N.2
-
109
-
-
84868115018
-
Regulators of G protein signaling: role in hematopoiesis, megakaryopoiesis and platelet function
-
Louwette S, Van Geet C, Freson K. Regulators of G protein signaling: role in hematopoiesis, megakaryopoiesis and platelet function. J Thromb Haemost (2012) 10:2215-22. doi:10.1111/j.1538-7836.2012.04903.x.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 2215-2222
-
-
Louwette, S.1
Van Geet, C.2
Freson, K.3
-
110
-
-
1542320537
-
G protein signaling: insights from new structures
-
Preininger AM, Hamm HE. G protein signaling: insights from new structures. Sci STKE (2004) 2004:re3. doi:10.1126/stke.2182004re3.
-
(2004)
Sci STKE
, vol.2004
-
-
Preininger, A.M.1
Hamm, H.E.2
-
111
-
-
0029808079
-
RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits
-
Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature (1996) 383:172-5. doi:10.1038/383172a0.
-
(1996)
Nature
, vol.383
, pp. 172-175
-
-
Watson, N.1
Linder, M.E.2
Druey, K.M.3
Kehrl, J.H.4
Blumer, K.J.5
-
112
-
-
27644503703
-
RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes
-
Berthebaud M. RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes. Blood (2005) 106:2962-8. doi:10.1182/blood-2005-02-0526.
-
(2005)
Blood
, vol.106
, pp. 2962-2968
-
-
Berthebaud, M.1
-
113
-
-
77449127999
-
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
-
Zernecke A, Bidzhekov K, Noels H, Shagdarsuren E, Gan L, Denecke B, et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal (2009) 2:ra81. doi:10.1126/scisignal.2000610.
-
(2009)
Sci Signal
, vol.2
-
-
Zernecke, A.1
Bidzhekov, K.2
Noels, H.3
Shagdarsuren, E.4
Gan, L.5
Denecke, B.6
-
114
-
-
0033209897
-
The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
-
Vila-Coro AJ, Rodriguez-Frade JM, Martin De Ana A, Moreno-Ortiz MC, Martinez-A C, Mellado M. The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J (1999) 13:1699-710.
-
(1999)
FASEB J
, vol.13
, pp. 1699-1710
-
-
Vila-Coro, A.J.1
Rodriguez-Frade, J.M.2
Martin De Ana, A.3
Moreno-Ortiz, M.C.4
Martinez-A, C.5
Mellado, M.6
-
115
-
-
0038297195
-
Chemokines integrate JAK/STAT and G-protein pathways during chemotaxis and calcium flux responses
-
Soriano SF, Serrano A, Hernanz-Falcón P, Ana AMD, Monterrubio M, Martínez-a C, et al. Chemokines integrate JAK/STAT and G-protein pathways during chemotaxis and calcium flux responses. Eur J Immunol (2003) 33:1328-33. doi:10.1002/eji.200323897.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1328-1333
-
-
Soriano, S.F.1
Serrano, A.2
Hernanz-Falcón, P.3
Ana, A.M.D.4
Monterrubio, M.5
Martínez-a, C.6
-
116
-
-
80052359992
-
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
-
Shukla AK, Xiao K, Lefkowitz RJ. Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem Sci (2011) 36:457-69. doi:10.1016/j.tibs.2011.06.003.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 457-469
-
-
Shukla, A.K.1
Xiao, K.2
Lefkowitz, R.J.3
-
118
-
-
8644249116
-
Intracellular localization and constitutive endocytosis of CXCR4 in human CD34 + hematopoietic progenitor cells
-
Zhang Y, Foudi A, Geay J-F, Berthebaud M, Buet D, Jarrier P, et al. Intracellular localization and constitutive endocytosis of CXCR4 in human CD34 + hematopoietic progenitor cells. Stem Cells (2004) 22:1015-29. doi:10.1634/stemcells.22-6-1015.
-
(2004)
Stem Cells
, vol.22
, pp. 1015-1029
-
-
Zhang, Y.1
Foudi, A.2
Geay, J.-F.3
Berthebaud, M.4
Buet, D.5
Jarrier, P.6
-
119
-
-
84903401891
-
Intracellular trafficking and endocytosis of CXCR4 in fetal mesenchymal stem/stromal cells
-
Pelekanos RA, Ting MJ, Sardesai VS, Ryan JM, Lim Y-C, Chan JKY, et al. Intracellular trafficking and endocytosis of CXCR4 in fetal mesenchymal stem/stromal cells. BMC Cell Biol (2014) 15:15. doi:10.1186/1471-2121-15-15.
-
(2014)
BMC Cell Biol
, vol.15
, pp. 15
-
-
Pelekanos, R.A.1
Ting, M.J.2
Sardesai, V.S.3
Ryan, J.M.4
Lim, Y.-C.5
Chan, J.K.Y.6
-
120
-
-
0033613938
-
Arrestin-dependent formation of 2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM. Arrestin-dependent formation of 2 adrenergic receptor-Src protein kinase complexes. Science (1999) 283:655-61. doi:10.1126/science.283.5402.655.
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
-
121
-
-
33644857279
-
Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor
-
Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, et al. Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem (2006) 281:1261-73. doi:10.1074/jbc. M506576200.
-
(2006)
J Biol Chem
, vol.281
, pp. 1261-1273
-
-
Shenoy, S.K.1
Drake, M.T.2
Nelson, C.D.3
Houtz, D.A.4
Xiao, K.5
Madabushi, S.6
-
122
-
-
78449300594
-
CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression
-
Sun X, Cheng G, Hao M, Zheng J, Zhou X, Zhang J, et al. CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev (2010) 29:709-22. doi:10.1007/s10555-010-9256-x.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 709-722
-
-
Sun, X.1
Cheng, G.2
Hao, M.3
Zheng, J.4
Zhou, X.5
Zhang, J.6
-
123
-
-
80052768977
-
CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration
-
Decaillot FM, Kazmi MA, Lin Y, Ray-Saha S, Sakmar TP, Sachdev P. CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration. J Biol Chem (2011) 286:32188-97. doi:10.1074/jbc. M111.277038.
-
(2011)
J Biol Chem
, vol.286
, pp. 32188-32197
-
-
Decaillot, F.M.1
Kazmi, M.A.2
Lin, Y.3
Ray-Saha, S.4
Sakmar, T.P.5
Sachdev, P.6
-
124
-
-
84875267735
-
CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4
-
Uto-Konomi A, McKibben B, Wirtz J, Sato Y, Takano A, Nanki T, et al. CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4. Biochem Biophys Res Commun (2013) 431:772-6. doi:10.1016/j.bbrc.2013.01.032.
-
(2013)
Biochem Biophys Res Commun
, vol.431
, pp. 772-776
-
-
Uto-Konomi, A.1
McKibben, B.2
Wirtz, J.3
Sato, Y.4
Takano, A.5
Nanki, T.6
-
125
-
-
56049124076
-
Physiological relevance of GPCR oligomerization and its impact on drug discovery
-
Panetta R, Greenwood MT. Physiological relevance of GPCR oligomerization and its impact on drug discovery. Drug Discov Today (2008) 13:1059-66. doi:10.1016/j.drudis.2008.09.002.
-
(2008)
Drug Discov Today
, vol.13
, pp. 1059-1066
-
-
Panetta, R.1
Greenwood, M.T.2
-
126
-
-
0037474238
-
Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor
-
Babcock GJ, Farzan M, Sodroski J. Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor. J Biol Chem (2003) 278:3378-85. doi:10.1074/jbc. M210140200.
-
(2003)
J Biol Chem
, vol.278
, pp. 3378-3385
-
-
Babcock, G.J.1
Farzan, M.2
Sodroski, J.3
-
127
-
-
58149299308
-
Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis
-
Hamatake M, Aoki T, Futahashi Y, Urano E, Yamamoto N, Komano J. Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis. Cancer Sci (2009) 100:95-102. doi:10.1111/j.1349-7006.2008.00997.x.
-
(2009)
Cancer Sci
, vol.100
, pp. 95-102
-
-
Hamatake, M.1
Aoki, T.2
Futahashi, Y.3
Urano, E.4
Yamamoto, N.5
Komano, J.6
-
128
-
-
3042690324
-
Regulation of CXCR4 receptor dimerization by the chemokine SDF-1alpha and the HIV-1 coat protein gp120: a fluorescence resonance energy transfer (FRET) study
-
Toth PT, Ren D, Miller RJ. Regulation of CXCR4 receptor dimerization by the chemokine SDF-1alpha and the HIV-1 coat protein gp120: a fluorescence resonance energy transfer (FRET) study. J Pharmacol Exp Ther (2004) 310:8-17. doi:10.1124/jpet.103.064956.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 8-17
-
-
Toth, P.T.1
Ren, D.2
Miller, R.J.3
-
129
-
-
84856859387
-
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions
-
Ray P, Lewin SA, Mihalko LA, Lesher-Perez SC, Takayama S, Luker KE, et al. Secreted CXCL12 (SDF-1) forms dimers under physiological conditions. Biochem J (2012) 442:433-42. doi:10.1042/BJ20111341.
-
(2012)
Biochem J
, vol.442
, pp. 433-442
-
-
Ray, P.1
Lewin, S.A.2
Mihalko, L.A.3
Lesher-Perez, S.C.4
Takayama, S.5
Luker, K.E.6
-
130
-
-
80055081893
-
Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
-
Drury LJ, Ziarek JJ, Gravel S, Veldkamp CT, Takekoshi T, Hwang ST, et al. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proc Natl Acad Sci U S A (2011) 108:17655-60. doi:10.1073/pnas.1101133108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 17655-17660
-
-
Drury, L.J.1
Ziarek, J.J.2
Gravel, S.3
Veldkamp, C.T.4
Takekoshi, T.5
Hwang, S.T.6
-
131
-
-
69249228563
-
A functional heteromeric MIF receptor formed by CD74 and CXCR4
-
Schwartz V, Lue H, Kraemer S, Korbiel J, Krohn R, Ohl K, et al. A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett (2009) 583:2749-57. doi:10.1016/j.febslet.2009.07.058.
-
(2009)
FEBS Lett
, vol.583
, pp. 2749-2757
-
-
Schwartz, V.1
Lue, H.2
Kraemer, S.3
Korbiel, J.4
Krohn, R.5
Ohl, K.6
-
132
-
-
0842285404
-
Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor
-
Rodríguez-Frade JM, Del Real G, Serrano A, Hernanz-Falcón P, Soriano SF, Vila-Coro AJ, et al. Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor. EMBO J (2004) 23:66-76. doi:10.1038/sj.emboj.7600020.
-
(2004)
EMBO J
, vol.23
, pp. 66-76
-
-
Rodríguez-Frade, J.M.1
Del Real, G.2
Serrano, A.3
Hernanz-Falcón, P.4
Soriano, S.F.5
Vila-Coro, A.J.6
-
133
-
-
21744444159
-
Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4
-
Wang J, Alvarez R, Roderiquez G, Guan E, Norcross MA. Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4. J Cell Biochem (2004) 93:753-60. doi:10.1002/jcb.20161.
-
(2004)
J Cell Biochem
, vol.93
, pp. 753-760
-
-
Wang, J.1
Alvarez, R.2
Roderiquez, G.3
Guan, E.4
Norcross, M.A.5
-
134
-
-
15444377047
-
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo-and heterodimers
-
Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, et al. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo-and heterodimers. J Biol Chem (2005) 280:9895-903. doi:10.1074/jbc. M411151200.
-
(2005)
J Biol Chem
, vol.280
, pp. 9895-9903
-
-
Percherancier, Y.1
Berchiche, Y.A.2
Slight, I.3
Volkmer-Engert, R.4
Tamamura, H.5
Fujii, N.6
-
135
-
-
35648971157
-
Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers
-
Sohy D, Parmentier M, Springael J-Y. Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers. J Biol Chem (2007) 282:30062-9. doi:10.1074/jbc. M705302200.
-
(2007)
J Biol Chem
, vol.282
, pp. 30062-30069
-
-
Sohy, D.1
Parmentier, M.2
Springael, J.-Y.3
-
136
-
-
48249131606
-
CXCR4-CCR5: a couple modulating T cell functions
-
Contento RL, Molon B, Boularan C, Pozzan T, Manes S, Marullo S, et al. CXCR4-CCR5: a couple modulating T cell functions. Proc Natl Acad Sci U S A (2008) 105:10101-6. doi:10.1073/pnas.0804286105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10101-10106
-
-
Contento, R.L.1
Molon, B.2
Boularan, C.3
Pozzan, T.4
Manes, S.5
Marullo, S.6
-
137
-
-
54849415924
-
Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors
-
Isik N, Hereld D, Jin T. Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors. PLoS One (2008) 3:e3424. doi:10.1371/journal.pone.0003424.
-
(2008)
PLoS One
, vol.3
-
-
Isik, N.1
Hereld, D.2
Jin, T.3
-
138
-
-
80051627970
-
Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses
-
Kremer KN, Clift IC, Miamen AG, Bamidele AO, Qian N-X, Humphreys TD, et al. Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses. J Immunol (2011) 187:1440-7. doi:10.4049/jimmunol.1100820.
-
(2011)
J Immunol
, vol.187
, pp. 1440-1447
-
-
Kremer, K.N.1
Clift, I.C.2
Miamen, A.G.3
Bamidele, A.O.4
Qian, N.-X.5
Humphreys, T.D.6
-
139
-
-
80053085853
-
Gai2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions
-
Kremer KN, Kumar A, Hedin KE. Gai2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions. J Immunol (2011) 187:3177-85. doi:10.4049/jimmunol.1100206.
-
(2011)
J Immunol
, vol.187
, pp. 3177-3185
-
-
Kremer, K.N.1
Kumar, A.2
Hedin, K.E.3
-
140
-
-
34548862317
-
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells
-
Patrussi L, Ulivieri C, Lucherini OM, Paccani SR, Gamberucci A, Lanfrancone L, et al. p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells. Blood (2007) 110:1730-8. doi:10.1182/blood-2007-01-068411.
-
(2007)
Blood
, vol.110
, pp. 1730-1738
-
-
Patrussi, L.1
Ulivieri, C.2
Lucherini, O.M.3
Paccani, S.R.4
Gamberucci, A.5
Lanfrancone, L.6
-
141
-
-
84881025063
-
Toll-like receptor 2-blocking antibodies promote angiogenesis and induce ERK1/2 and AKT signaling via CXCR4 in endothelial cells
-
Wagner NM, Bierhansl L, Noldge-Schomburg G, Vollmar B, Roesner JP. Toll-like receptor 2-blocking antibodies promote angiogenesis and induce ERK1/2 and AKT signaling via CXCR4 in endothelial cells. Arterioscler Thromb Vasc Biol (2013) 33:1943-51. doi:10.1161/ATVBAHA.113.301783.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 1943-1951
-
-
Wagner, N.M.1
Bierhansl, L.2
Noldge-Schomburg, G.3
Vollmar, B.4
Roesner, J.P.5
-
142
-
-
84926687767
-
Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility
-
Hsiao JJ, Ng BH, Smits MM, Wang J, Jasavala RJ, Martinez HD, et al. Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility. BMC Cancer (2015) 15:204. doi:10.1186/s12885-015-1201-5.
-
(2015)
BMC Cancer
, vol.15
, pp. 204
-
-
Hsiao, J.J.1
Ng, B.H.2
Smits, M.M.3
Wang, J.4
Jasavala, R.J.5
Martinez, H.D.6
-
143
-
-
84961289810
-
Heteromerization of chemokine (C-X-C motif) receptor 4 with a 1A/B-adrenergic receptors controls a 1-adrenergic receptor function
-
Tripathi A, Vana PG, Chavan TS, Brueggemann LI, Byron KL, Tarasova NI, et al. Heteromerization of chemokine (C-X-C motif) receptor 4 with a 1A/B-adrenergic receptors controls a 1-adrenergic receptor function. Proc Natl Acad Sci U S A (2015) 112:1659-E1668. doi:10.1073/pnas.1417564112.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 1659-E1668
-
-
Tripathi, A.1
Vana, P.G.2
Chavan, T.S.3
Brueggemann, L.I.4
Byron, K.L.5
Tarasova, N.I.6
-
144
-
-
84877995317
-
Hetero-oligomerization of chemokine receptors: diversity and relevance for function
-
Kraemer S, Alampour-Rajabi S, El Bounkari O, Bernhagen J. Hetero-oligomerization of chemokine receptors: diversity and relevance for function. Curr Med Chem (2013) 20:2524-36. doi:10.2174/09298673113209990117.
-
(2013)
Curr Med Chem
, vol.20
, pp. 2524-2536
-
-
Kraemer, S.1
Alampour-Rajabi, S.2
El Bounkari, O.3
Bernhagen, J.4
-
145
-
-
84860361435
-
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
-
Schiraldi M, Raucci A, Munoz LM, Livoti E, Celona B, Venereau E, et al. HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J Exp Med (2012) 209:551-63. doi:10.1084/jem.20111739.
-
(2012)
J Exp Med
, vol.209
, pp. 551-563
-
-
Schiraldi, M.1
Raucci, A.2
Munoz, L.M.3
Livoti, E.4
Celona, B.5
Venereau, E.6
-
146
-
-
0038627759
-
Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of toll-like receptor 4 (TLR4)
-
Roger T, Froidevaux C, Martin C, Calandra T. Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of toll-like receptor 4 (TLR4). J Endotoxin Res (2003) 9:119-23. doi:10.1177/09680519030090020801.
-
(2003)
J Endotoxin Res
, vol.9
, pp. 119-123
-
-
Roger, T.1
Froidevaux, C.2
Martin, C.3
Calandra, T.4
-
147
-
-
57049184633
-
Macrophage migration inhibitory factor: a key cytokine in RA, SLE and atherosclerosis
-
Santos LL, Morand EF. Macrophage migration inhibitory factor: a key cytokine in RA, SLE and atherosclerosis. Clin Chim Acta (2009) 399:1-7. doi:10.1016/j.cca.2008.09.014.
-
(2009)
Clin Chim Acta
, vol.399
, pp. 1-7
-
-
Santos, L.L.1
Morand, E.F.2
-
148
-
-
84939553684
-
Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis
-
De Souza HS, Tortori CA, Lintomen L, Figueiredo RT, Bernardazzi C, Leng L, et al. Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis. Mucosal Immunol (2015). doi:10.1038/mi.2015.6.
-
(2015)
Mucosal Immunol
-
-
De Souza, H.S.1
Tortori, C.A.2
Lintomen, L.3
Figueiredo, R.T.4
Bernardazzi, C.5
Leng, L.6
-
149
-
-
84934951599
-
Macrophage migration inhibitory factor mediates PAR-induced bladder pain
-
Kouzoukas DE, Meyer-Siegler KL, Ma F, Westlund KN, Hunt DE, Vera PL. Macrophage migration inhibitory factor mediates PAR-induced bladder pain. PLoS One (2015) 10:e0127628. doi:10.1371/journal.pone.0127628.
-
(2015)
PLoS One
, vol.10
-
-
Kouzoukas, D.E.1
Meyer-Siegler, K.L.2
Ma, F.3
Westlund, K.N.4
Hunt, D.E.5
Vera, P.L.6
-
150
-
-
38749137749
-
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
-
Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, et al. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature (2008) 451:578-82. doi:10.1038/nature06504.
-
(2008)
Nature
, vol.451
, pp. 578-582
-
-
Miller, E.J.1
Li, J.2
Leng, L.3
McDonald, C.4
Atsumi, T.5
Bucala, R.6
-
151
-
-
84879547269
-
What is the significance of perioperative release of macrophage migration inhibitory factor in cardiac surgery?
-
Stoppe C, Werker T, Rossaint R, Dollo F, Lue H, Wonisch W, et al. What is the significance of perioperative release of macrophage migration inhibitory factor in cardiac surgery? Antioxid Redox Signal (2013) 19:231-9. doi:10.1089/ars.2012.5015.
-
(2013)
Antioxid Redox Signal
, vol.19
, pp. 231-239
-
-
Stoppe, C.1
Werker, T.2
Rossaint, R.3
Dollo, F.4
Lue, H.5
Wonisch, W.6
-
152
-
-
84899865530
-
The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning
-
Goetzenich A, Kraemer S, Rossaint R, Bleilevens C, Dollo F, Siry L, et al. The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning. PLoS One (2014) 9:e92827. doi:10.1371/journal.pone.0092827.
-
(2014)
PLoS One
, vol.9
-
-
Goetzenich, A.1
Kraemer, S.2
Rossaint, R.3
Bleilevens, C.4
Dollo, F.5
Siry, L.6
-
153
-
-
84919708689
-
Protective role of macrophage migration inhibitory factor in nonalcoholic steatohepatitis
-
Heinrichs D, Berres ML, Coeuru M, Knauel M, Nellen A, Fischer P, et al. Protective role of macrophage migration inhibitory factor in nonalcoholic steatohepatitis. FASEB J (2014) 28:5136-47. doi:10.1096/fj.14-256776.
-
(2014)
FASEB J
, vol.28
, pp. 5136-5147
-
-
Heinrichs, D.1
Berres, M.L.2
Coeuru, M.3
Knauel, M.4
Nellen, A.5
Fischer, P.6
-
154
-
-
84923258878
-
Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex
-
Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, et al. Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun (2014) 5:5611. doi:10.1038/ncomms6611.
-
(2014)
Nat Commun
, vol.5
, pp. 5611
-
-
Arno, B.1
Grassivaro, F.2
Rossi, C.3
Bergamaschi, A.4
Castiglioni, V.5
Furlan, R.6
-
155
-
-
12444285441
-
MIF signal transduction initiated by binding to CD74
-
Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, et al. MIF signal transduction initiated by binding to CD74. J Exp Med (2003) 197:1467-76. doi:10.1084/jem.20030286.
-
(2003)
J Exp Med
, vol.197
, pp. 1467-1476
-
-
Leng, L.1
Metz, C.N.2
Fang, Y.3
Xu, J.4
Donnelly, S.5
Baugh, J.6
-
156
-
-
33749508911
-
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex
-
Shi X, Leng L, Wang T, Wang W, Du X, Li J, et al. CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity (2006) 25:595-606. doi:10.1016/j.immuni.2006.08.020.
-
(2006)
Immunity
, vol.25
, pp. 595-606
-
-
Shi, X.1
Leng, L.2
Wang, T.3
Wang, W.4
Du, X.5
Li, J.6
-
157
-
-
40949087882
-
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
-
Gore Y, Starlets D, Maharshak N, Becker-Herman S, Kaneyuki U, Leng L, et al. Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J Biol Chem (2008) 283:2784-92. doi:10.1074/jbc. M703265200.
-
(2008)
J Biol Chem
, vol.283
, pp. 2784-2792
-
-
Gore, Y.1
Starlets, D.2
Maharshak, N.3
Becker-Herman, S.4
Kaneyuki, U.5
Leng, L.6
-
158
-
-
77954926921
-
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
-
Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, et al. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A (2010) 107:11313-8. doi:10.1073/pnas.1002716107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11313-11318
-
-
Cho, Y.1
Crichlow, G.V.2
Vermeire, J.J.3
Leng, L.4
Du, X.5
Hodsdon, M.E.6
-
159
-
-
79953295567
-
Hypoxia-induced endothelial secretion of macrophage migration inhibitory factor and role in endothelial progenitor cell recruitment
-
Simons D, Grieb G, Hristov M, Pallua N, Weber C, Bernhagen J, et al. Hypoxia-induced endothelial secretion of macrophage migration inhibitory factor and role in endothelial progenitor cell recruitment. J Cell Mol Med (2011) 15:668-78. doi:10.1111/j.1582-4934.2010.01041.x.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 668-678
-
-
Simons, D.1
Grieb, G.2
Hristov, M.3
Pallua, N.4
Weber, C.5
Bernhagen, J.6
-
160
-
-
84869420406
-
Stromal cell-derived factor-1alpha and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells
-
Shin HN, Moon HH, Ku JL. Stromal cell-derived factor-1alpha and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells. Int J Mol Med (2012) 30:1537-43. doi:10.3892/ijmm.2012.1141.
-
(2012)
Int J Mol Med
, vol.30
, pp. 1537-1543
-
-
Shin, H.N.1
Moon, H.H.2
Ku, J.L.3
-
161
-
-
84901257731
-
MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling
-
Klasen C, Ohl K, Sternkopf M, Shachar I, Schmitz C, Heussen N, et al. MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling. J Immunol (2014) 192:5273-84. doi:10.4049/jimmunol.1302209.
-
(2014)
J Immunol
, vol.192
, pp. 5273-5284
-
-
Klasen, C.1
Ohl, K.2
Sternkopf, M.3
Shachar, I.4
Schmitz, C.5
Heussen, N.6
-
162
-
-
84925855133
-
Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors
-
Lourenco S, Teixeira VH, Kalber T, Jose RJ, Floto RA, Janes SM. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol (2015) 194:3463-74. doi:10.4049/jimmunol.1402097.
-
(2015)
J Immunol
, vol.194
, pp. 3463-3474
-
-
Lourenco, S.1
Teixeira, V.H.2
Kalber, T.3
Jose, R.J.4
Floto, R.A.5
Janes, S.M.6
-
163
-
-
57549116143
-
Cyclophosphamide-induced cystitis increases bladder CXCR4 expression and CXCR4-macrophage migration inhibitory factor association
-
Vera PL, Iczkowski KA, Wang X, Meyer-Siegler KL. Cyclophosphamide-induced cystitis increases bladder CXCR4 expression and CXCR4-macrophage migration inhibitory factor association. PLoS One (2008) 3:e3898. doi:10.1371/journal.pone.0003898.
-
(2008)
PLoS One
, vol.3
-
-
Vera, P.L.1
Iczkowski, K.A.2
Wang, X.3
Meyer-Siegler, K.L.4
-
164
-
-
77955284816
-
ZAP-70: an essential kinase in T-cell signaling
-
Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, et al. ZAP-70: an essential kinase in T-cell signaling. Cold Spring Harb Perspect Biol (2010) 2:a002279. doi:10.1101/cshperspect.a002279.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
-
-
Wang, H.1
Kadlecek, T.A.2
Au-Yeung, B.B.3
Goodfellow, H.E.4
Hsu, L.Y.5
Freedman, T.S.6
-
165
-
-
77953622062
-
Zap70 controls the interaction of talin with integrin to regulate the chemotactic directionality of T-cell migration
-
Lin YP, Cheng YJ, Huang JY, Lin HC, Yang BC. Zap70 controls the interaction of talin with integrin to regulate the chemotactic directionality of T-cell migration. Mol Immunol (2010) 47:2022-9. doi:10.1016/j.molimm.2010.04.011.
-
(2010)
Mol Immunol
, vol.47
, pp. 2022-2029
-
-
Lin, Y.P.1
Cheng, Y.J.2
Huang, J.Y.3
Lin, H.C.4
Yang, B.C.5
-
166
-
-
77953149880
-
Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells
-
Dessein AF, Stechly L, Jonckheere N, Dumont P, Monte D, Leteurtre E, et al. Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells. Cancer Res (2010) 70:4644-54. doi:10.1158/0008-5472.CAN-09-3828.
-
(2010)
Cancer Res
, vol.70
, pp. 4644-4654
-
-
Dessein, A.F.1
Stechly, L.2
Jonckheere, N.3
Dumont, P.4
Monte, D.5
Leteurtre, E.6
-
167
-
-
84900413193
-
HIF-alpha/MIF and NF-kappaB/IL-6 axes contribute to the recruitment of CD11b+Gr-1+ myeloid cells in hypoxic microenvironment of HNSCC
-
Zhu G, Tang Y, Geng N, Zheng M, Jiang J, Li L, et al. HIF-alpha/MIF and NF-kappaB/IL-6 axes contribute to the recruitment of CD11b+Gr-1+ myeloid cells in hypoxic microenvironment of HNSCC. Neoplasia (2014) 16:168-79. doi:10.1593/neo.132034.
-
(2014)
Neoplasia
, vol.16
, pp. 168-179
-
-
Zhu, G.1
Tang, Y.2
Geng, N.3
Zheng, M.4
Jiang, J.5
Li, L.6
-
168
-
-
34547820876
-
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
-
Shojaei F, Wu X, Malik AK, Zhong C, Baldwin ME, Schanz S, et al. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat Biotechnol (2007) 25:911-20. doi:10.1038/nbt1323.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 911-920
-
-
Shojaei, F.1
Wu, X.2
Malik, A.K.3
Zhong, C.4
Baldwin, M.E.5
Schanz, S.6
-
169
-
-
37349100945
-
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
-
Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, et al. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell (2008) 13:23-35. doi:10.1016/j.ccr.2007.12.004.
-
(2008)
Cancer Cell
, vol.13
, pp. 23-35
-
-
Yang, L.1
Huang, J.2
Ren, X.3
Gorska, A.E.4
Chytil, A.5
Aakre, M.6
-
170
-
-
84867416852
-
Tumor microenvironment macrophage inhibitory factor directs the accumulation of interleukin-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients
-
Li J, Mo HY, Xiong G, Zhang L, He J, Huang ZF, et al. Tumor microenvironment macrophage inhibitory factor directs the accumulation of interleukin-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients. J Biol Chem (2012) 287:35484-95. doi:10.1074/jbc. M112.367532.
-
(2012)
J Biol Chem
, vol.287
, pp. 35484-35495
-
-
Li, J.1
Mo, H.Y.2
Xiong, G.3
Zhang, L.4
He, J.5
Huang, Z.F.6
-
171
-
-
69849107597
-
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
-
Kryczek I, Banerjee M, Cheng P, Vatan L, Szeliga W, Wei S, et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood (2009) 114:1141-9. doi:10.1182/blood-2009-03-208249.
-
(2009)
Blood
, vol.114
, pp. 1141-1149
-
-
Kryczek, I.1
Banerjee, M.2
Cheng, P.3
Vatan, L.4
Szeliga, W.5
Wei, S.6
-
172
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang JP, Yan J, Xu J, Pang XH, Chen MS, Li L, et al. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol (2009) 50:980-9. doi:10.1016/j.jhep.2008.12.033.
-
(2009)
J Hepatol
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
Pang, X.H.4
Chen, M.S.5
Li, L.6
-
173
-
-
84860252668
-
Role for CD74 and CXCR4 in clathrin-dependent endocytosis of the cytokine MIF
-
Schwartz V, Kruttgen A, Weis J, Weber C, Ostendorf T, Lue H, et al. Role for CD74 and CXCR4 in clathrin-dependent endocytosis of the cytokine MIF. Eur J Cell Biol (2012) 91:435-49. doi:10.1016/j.ejcb.2011.08.006.
-
(2012)
Eur J Cell Biol
, vol.91
, pp. 435-449
-
-
Schwartz, V.1
Kruttgen, A.2
Weis, J.3
Weber, C.4
Ostendorf, T.5
Lue, H.6
-
174
-
-
77957788545
-
Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74
-
Lue H, Dewor M, Leng L, Bucala R, Bernhagen J. Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74. Cell Signal (2011) 23:135-44. doi:10.1016/j.cellsig.2010.08.013.
-
(2011)
Cell Signal
, vol.23
, pp. 135-144
-
-
Lue, H.1
Dewor, M.2
Leng, L.3
Bucala, R.4
Bernhagen, J.5
-
175
-
-
84873780558
-
In vitro cell migration as a model for delayed hypersensitivity
-
George M, Vaughan JH. In vitro cell migration as a model for delayed hypersensitivity. Proc Soc Exp Biol Med (1962) 111:514-21. doi:10.3181/00379727-111-27841.
-
(1962)
Proc Soc Exp Biol Med
, vol.111
, pp. 514-521
-
-
George, M.1
Vaughan, J.H.2
-
176
-
-
0013923944
-
Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction
-
David JR. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci U S A (1966) 56:72-7. doi:10.1073/pnas.56.1.72.
-
(1966)
Proc Natl Acad Sci U S A
, vol.56
, pp. 72-77
-
-
David, J.R.1
-
177
-
-
0033613089
-
Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration
-
Hermanowski-Vosatka A, Mundt SS, Ayala JM, Goyal S, Hanlon WA, Czerwinski RM, et al. Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration. Biochemistry (1999) 38:12841-9. doi:10.1021/bi991352p.
-
(1999)
Biochemistry
, vol.38
, pp. 12841-12849
-
-
Hermanowski-Vosatka, A.1
Mundt, S.S.2
Ayala, J.M.3
Goyal, S.4
Hanlon, W.A.5
Czerwinski, R.M.6
-
178
-
-
84901981443
-
MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells
-
Dicosmo-Ponticello CJ, Hoover D, Coffman FD, Cohen S, Cohen MC. MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells. Cytokine (2014) 69:47-55. doi:10.1016/j.cyto.2014.05.005.
-
(2014)
Cytokine
, vol.69
, pp. 47-55
-
-
Dicosmo-Ponticello, C.J.1
Hoover, D.2
Coffman, F.D.3
Cohen, S.4
Cohen, M.C.5
-
179
-
-
84862777608
-
Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4+ T cell resistance and enrichment
-
Yuan J, Wang J, Crain K, Fearns C, Kim KA, Hua KL, et al. Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4+ T cell resistance and enrichment. Mol Ther (2012) 20:849-59. doi:10.1038/mt.2011.310.
-
(2012)
Mol Ther
, vol.20
, pp. 849-859
-
-
Yuan, J.1
Wang, J.2
Crain, K.3
Fearns, C.4
Kim, K.A.5
Hua, K.L.6
-
180
-
-
29144497998
-
Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease
-
Penela P, Murga C, Ribas C, Tutor AS, Peregrin S, Mayor F Jr. Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovasc Res (2006) 69:46-56. doi:10.1016/j.cardiores.2005.09.011.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 46-56
-
-
Penela, P.1
Murga, C.2
Ribas, C.3
Tutor, A.S.4
Peregrin, S.5
Mayor, F.6
-
181
-
-
0027485593
-
Increase in plasma concentration of ubiquitin in dialysis patients: possible involvement in beta 2-microglobulin amyloidosis
-
Okada M, Miyazaki S, Hirasawa Y. Increase in plasma concentration of ubiquitin in dialysis patients: possible involvement in beta 2-microglobulin amyloidosis. Clin Chim Acta (1993) 220:135-44. doi:10.1016/0009-8981(93)90042-3.
-
(1993)
Clin Chim Acta
, vol.220
, pp. 135-144
-
-
Okada, M.1
Miyazaki, S.2
Hirasawa, Y.3
-
182
-
-
40549108584
-
Systemic ubiquitin release after blunt trauma and burns: association with injury severity, posttraumatic complications, and survival
-
Majetschak M, Zedler S, Hostmann A, Sorell LT, Patel MB, Novar LT, et al. Systemic ubiquitin release after blunt trauma and burns: association with injury severity, posttraumatic complications, and survival. J Trauma (2008) 64:586-96. doi:10.1097/TA.0b013e3181641bc5.
-
(2008)
J Trauma
, vol.64
, pp. 586-596
-
-
Majetschak, M.1
Zedler, S.2
Hostmann, A.3
Sorell, L.T.4
Patel, M.B.5
Novar, L.T.6
-
183
-
-
0034655577
-
Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells
-
Daino H, Matsumura I, Takada K, Odajima J, Tanaka H, Ueda S, et al. Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells. Blood (2000) 95:2577-85.
-
(2000)
Blood
, vol.95
, pp. 2577-2585
-
-
Daino, H.1
Matsumura, I.2
Takada, K.3
Odajima, J.4
Tanaka, H.5
Ueda, S.6
-
184
-
-
33645074163
-
Targeting the monocytic ubiquitin system with extracellular ubiquitin
-
Majetschak M, Ponelies N, Hirsch T. Targeting the monocytic ubiquitin system with extracellular ubiquitin. Immunol Cell Biol (2006) 84:59-65. doi:10.1111/j.1440-1711.2005.01399.x.
-
(2006)
Immunol Cell Biol
, vol.84
, pp. 59-65
-
-
Majetschak, M.1
Ponelies, N.2
Hirsch, T.3
-
185
-
-
80052984088
-
Ubiquitin receptor binding and signaling in primary human leukocytes
-
Saini V, Romero J, Marchese A, Majetschak M. Ubiquitin receptor binding and signaling in primary human leukocytes. Commun Integr Biol (2010) 3:608-10. doi:10.4161/cib.3.6.13375.
-
(2010)
Commun Integr Biol
, vol.3
, pp. 608-610
-
-
Saini, V.1
Romero, J.2
Marchese, A.3
Majetschak, M.4
-
186
-
-
84879247089
-
Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification
-
Tripathi A, Saini V, Marchese A, Volkman BF, Tang WJ, Majetschak M. Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification. Biochemistry (2013) 52:4184-92. doi:10.1021/bi400254f.
-
(2013)
Biochemistry
, vol.52
, pp. 4184-4192
-
-
Tripathi, A.1
Saini, V.2
Marchese, A.3
Volkman, B.F.4
Tang, W.J.5
Majetschak, M.6
-
187
-
-
84883475479
-
The ubiquitin-CXCR4 axis plays an important role in acute lung infection-enhanced lung tumor metastasis
-
Yan L, Cai Q, Xu Y. The ubiquitin-CXCR4 axis plays an important role in acute lung infection-enhanced lung tumor metastasis. Clin Cancer Res (2013) 19:4706-16. doi:10.1158/1078-0432.CCR-13-0011.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4706-4716
-
-
Yan, L.1
Cai, Q.2
Xu, Y.3
-
188
-
-
84892483373
-
CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1alpha and ubiquitin
-
Tripathi A, Davis JD, Staren DM, Volkman BF, Majetschak M. CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1alpha and ubiquitin. Cytokine (2014) 65:121-5. doi:10.1016/j.cyto.2013.12.008.
-
(2014)
Cytokine
, vol.65
, pp. 121-125
-
-
Tripathi, A.1
Davis, J.D.2
Staren, D.M.3
Volkman, B.F.4
Majetschak, M.5
-
189
-
-
79551684420
-
Ubiquitin is a novel substrate for human insulin-degrading enzyme
-
Ralat LA, Kalas V, Zheng Z, Goldman RD, Sosnick TR, Tang WJ. Ubiquitin is a novel substrate for human insulin-degrading enzyme. J Mol Biol (2011) 406:454-66. doi:10.1016/j.jmb.2010.12.026.
-
(2011)
J Mol Biol
, vol.406
, pp. 454-466
-
-
Ralat, L.A.1
Kalas, V.2
Zheng, Z.3
Goldman, R.D.4
Sosnick, T.R.5
Tang, W.J.6
-
190
-
-
0035139777
-
Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes
-
Vlahakis SR, Algeciras-Schimnich A, Bou G, Heppelmann CJ, Villasis-Keever A, Collman RG, et al. Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes. J Clin Invest (2001) 107:207-15. doi:10.1172/JCI11109.
-
(2001)
J Clin Invest
, vol.107
, pp. 207-215
-
-
Vlahakis, S.R.1
Algeciras-Schimnich, A.2
Bou, G.3
Heppelmann, C.J.4
Villasis-Keever, A.5
Collman, R.G.6
-
191
-
-
0032492918
-
Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4
-
Hesselgesser J, Taub D, Baskar P, Greenberg M, Hoxie J, Kolson DL, et al. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr Biol (1998) 8:595-8. doi:10.1016/S0960-9822(98)70230-1.
-
(1998)
Curr Biol
, vol.8
, pp. 595-598
-
-
Hesselgesser, J.1
Taub, D.2
Baskar, P.3
Greenberg, M.4
Hoxie, J.5
Kolson, D.L.6
-
192
-
-
84908135432
-
HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-Gp120 aptamer
-
Lopes De Campos WR, Chirwa N, London G, Rotherham LS, Morris L, Mayosi BM, et al. HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-Gp120 aptamer. PLoS One (2014) 9:e110930. doi:10.1371/journal.pone.0110930.
-
(2014)
PLoS One
, vol.9
-
-
Lopes De Campos, W.R.1
Chirwa, N.2
London, G.3
Rotherham, L.S.4
Morris, L.5
Mayosi, B.M.6
-
193
-
-
0346874146
-
Human immunodeficiency virus-induced apoptosis of human hepatocytes via CXCR4
-
Vlahakis SR, Villasis-Keever A, Gomez TS, Bren GD, Paya CV. Human immunodeficiency virus-induced apoptosis of human hepatocytes via CXCR4. J Infect Dis (2003) 188:1455-60. doi:10.1086/379738.
-
(2003)
J Infect Dis
, vol.188
, pp. 1455-1460
-
-
Vlahakis, S.R.1
Villasis-Keever, A.2
Gomez, T.S.3
Bren, G.D.4
Paya, C.V.5
-
194
-
-
40449120292
-
Human immunodeficiency virus-induced apoptosis of human breast cancer cells via CXCR4 is mediated by the viral envelope protein but does not require CD4
-
Endo M, Inatsu A, Hashimoto K, Takamune N, Shoji S, Misumi S. Human immunodeficiency virus-induced apoptosis of human breast cancer cells via CXCR4 is mediated by the viral envelope protein but does not require CD4. Curr HIV Res (2008) 6:34-42. doi:10.2174/157016208783571991.
-
(2008)
Curr HIV Res
, vol.6
, pp. 34-42
-
-
Endo, M.1
Inatsu, A.2
Hashimoto, K.3
Takamune, N.4
Shoji, S.5
Misumi, S.6
-
195
-
-
58149505569
-
CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth
-
Singh S, Bond VC, Powell M, Singh UP, Bumpers HL, Grizzle WE, et al. CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth. Mol Cancer Ther (2009) 8:178-84. doi:10.1158/1535-7163.MCT-08-0643.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 178-184
-
-
Singh, S.1
Bond, V.C.2
Powell, M.3
Singh, U.P.4
Bumpers, H.L.5
Grizzle, W.E.6
-
196
-
-
0033040696
-
The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling
-
Blanco J, Jacotot E, Cabrera C, Cardona A, Clotet B, De Clercq E, et al. The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling. AIDS (1999) 13:909-17. doi:10.1097/00002030-199905280-00006.
-
(1999)
AIDS
, vol.13
, pp. 909-917
-
-
Blanco, J.1
Jacotot, E.2
Cabrera, C.3
Cardona, A.4
Clotet, B.5
De Clercq, E.6
-
197
-
-
0034654568
-
Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120)
-
Biard-Piechaczyk M, Robert-Hebmann V, Richard V, Roland J, Hipskind RA, Devaux C. Caspase-dependent apoptosis of cells expressing the chemokine receptor CXCR4 is induced by cell membrane-associated human immunodeficiency virus type 1 envelope glycoprotein (gp120). Virology (2000) 268:329-44. doi:10.1006/viro.1999.0151.
-
(2000)
Virology
, vol.268
, pp. 329-344
-
-
Biard-Piechaczyk, M.1
Robert-Hebmann, V.2
Richard, V.3
Roland, J.4
Hipskind, R.A.5
Devaux, C.6
-
198
-
-
34247176811
-
Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4
-
Trushin SA, Algeciras-Schimnich A, Vlahakis SR, Bren GD, Warren S, Schnepple DJ, et al. Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4. J Immunol (2007) 178:4846-53. doi:10.4049/jimmunol.178.8.4846.
-
(2007)
J Immunol
, vol.178
, pp. 4846-4853
-
-
Trushin, S.A.1
Algeciras-Schimnich, A.2
Vlahakis, S.R.3
Bren, G.D.4
Warren, S.5
Schnepple, D.J.6
-
199
-
-
33744960104
-
HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45
-
Anand AR, Ganju RK. HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45. J Biol Chem (2006) 281:12289-99. doi:10.1074/jbc. M511786200.
-
(2006)
J Biol Chem
, vol.281
, pp. 12289-12299
-
-
Anand, A.R.1
Ganju, R.K.2
-
200
-
-
0034715893
-
Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size
-
Ferri KF, Jacotot E, Leduc P, Geuskens M, Ingber DE, Kroemer G. Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. Exp Cell Res (2000) 261:119-26. doi:10.1006/excr.2000.5062.
-
(2000)
Exp Cell Res
, vol.261
, pp. 119-126
-
-
Ferri, K.F.1
Jacotot, E.2
Leduc, P.3
Geuskens, M.4
Ingber, D.E.5
Kroemer, G.6
-
201
-
-
0035887446
-
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation
-
Castedo M, Ferri KF, Blanco J, Roumier T, Larochette N, Barretina J, et al. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med (2001) 194:1097-110. doi:10.1084/jem.194.8.1097.
-
(2001)
J Exp Med
, vol.194
, pp. 1097-1110
-
-
Castedo, M.1
Ferri, K.F.2
Blanco, J.3
Roumier, T.4
Larochette, N.5
Barretina, J.6
-
202
-
-
34748873419
-
Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope
-
Molina L, Grimaldi M, Robert-Hebmann V, Espert L, Varbanov M, Devaux C, et al. Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope. Proteomics (2007) 7:3116-30. doi:10.1002/pmic.200700306.
-
(2007)
Proteomics
, vol.7
, pp. 3116-3130
-
-
Molina, L.1
Grimaldi, M.2
Robert-Hebmann, V.3
Espert, L.4
Varbanov, M.5
Devaux, C.6
-
203
-
-
58149083753
-
HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells
-
Denizot M, Varbanov M, Espert L, Robert-Hebmann V, Sagnier S, Garcia E, et al. HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells. Autophagy (2008) 4:998-1008. doi:10.4161/auto.6880.
-
(2008)
Autophagy
, vol.4
, pp. 998-1008
-
-
Denizot, M.1
Varbanov, M.2
Espert, L.3
Robert-Hebmann, V.4
Sagnier, S.5
Garcia, E.6
-
204
-
-
84922779010
-
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors
-
Wu CH, Wang CJ, Chang CP, Cheng YC, Song JS, Jan JJ, et al. Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors. J Med Chem (2015) 58(3):1452-65. doi:10.1021/jm501772w.
-
(2015)
J Med Chem
, vol.58
, Issue.3
, pp. 1452-1465
-
-
Wu, C.H.1
Wang, C.J.2
Chang, C.P.3
Cheng, Y.C.4
Song, J.S.5
Jan, J.J.6
-
205
-
-
0024345984
-
Selective amplification and cloning of four new members of the G protein-coupled receptor family
-
Libert F, Parmentier M, Lefort A, Dinsart C, Van Sande J, Maenhaut C, et al. Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science (1989) 244:569-72. doi:10.1126/science.2541503.
-
(1989)
Science
, vol.244
, pp. 569-572
-
-
Libert, F.1
Parmentier, M.2
Lefort, A.3
Dinsart, C.4
Van Sande, J.5
Maenhaut, C.6
-
206
-
-
0025266746
-
Complete nucleotide sequence of a putative G protein coupled receptor: RDC1
-
Liert F, Parmentier M, Lefort A, Dumont JE, Vassart G. Complete nucleotide sequence of a putative G protein coupled receptor: RDC1. Nucleic Acids Res (1990) 18:1917. doi:10.1093/nar/18.7.1917.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 1917
-
-
Liert, F.1
Parmentier, M.2
Lefort, A.3
Dumont, J.E.4
Vassart, G.5
-
207
-
-
0031888981
-
Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1
-
Heesen M, Berman MA, Charest A, Housman D, Gerard C, Dorf ME. Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1. Immunogenetics (1998) 47:364-70. doi:10.1007/s002510050371.
-
(1998)
Immunogenetics
, vol.47
, pp. 364-370
-
-
Heesen, M.1
Berman, M.A.2
Charest, A.3
Housman, D.4
Gerard, C.5
Dorf, M.E.6
-
208
-
-
33748474838
-
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
-
Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med (2006) 203:2201-13. doi:10.1084/jem.20052144.
-
(2006)
J Exp Med
, vol.203
, pp. 2201-2213
-
-
Burns, J.M.1
Summers, B.C.2
Wang, Y.3
Melikian, A.4
Berahovich, R.5
Miao, Z.6
-
209
-
-
77949482428
-
CXCR7 functions as a scavenger for CXCL12 and CXCL11
-
Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, et al. CXCR7 functions as a scavenger for CXCL12 and CXCL11. PLoS One (2010) 5:e9175. doi:10.1371/journal.pone.0009175.
-
(2010)
PLoS One
, vol.5
-
-
Naumann, U.1
Cameroni, E.2
Pruenster, M.3
Mahabaleshwar, H.4
Raz, E.5
Zerwes, H.G.6
-
210
-
-
35648945337
-
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
-
Miao Z, Luker KE, Summers BC, Berahovich R, Bhojani MS, Rehemtulla A, et al. CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc Natl Acad Sci U S A (2007) 104:15735-40. doi:10.1073/pnas.0610444104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15735-15740
-
-
Miao, Z.1
Luker, K.E.2
Summers, B.C.3
Berahovich, R.4
Bhojani, M.S.5
Rehemtulla, A.6
-
211
-
-
70350317612
-
CXCL12, CXCR4 and CXCR7 expression in brain metastases
-
Salmaggi A, Maderna E, Calatozzolo C, Gaviani P, Canazza A, Milanesi I, et al. CXCL12, CXCR4 and CXCR7 expression in brain metastases. Cancer Biol Ther (2009) 8:1608-14. doi:10.4161/cbt.8.17.9202.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1608-1614
-
-
Salmaggi, A.1
Maderna, E.2
Calatozzolo, C.3
Gaviani, P.4
Canazza, A.5
Milanesi, I.6
-
212
-
-
78649256331
-
Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer
-
D'Alterio C, Consales C, Polimeno M, Franco R, Cindolo L, Portella L, et al. Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer. Curr Cancer Drug Targets (2010) 10:772-81. doi:10.2174/156800910793605839.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 772-781
-
-
D'Alterio, C.1
Consales, C.2
Polimeno, M.3
Franco, R.4
Cindolo, L.5
Portella, L.6
-
213
-
-
84894254008
-
Expression of stromal cell-derived factor-1 receptors CXCR4 and CXCR7 on circulating platelets of patients with acute coronary syndrome and association with left ventricular functional recovery
-
Rath D, Chatterjee M, Borst O, Muller K, Stellos K, Mack AF, et al. Expression of stromal cell-derived factor-1 receptors CXCR4 and CXCR7 on circulating platelets of patients with acute coronary syndrome and association with left ventricular functional recovery. Eur Heart J (2014) 35:386-94. doi:10.1093/eurheartj/eht448.
-
(2014)
Eur Heart J
, vol.35
, pp. 386-394
-
-
Rath, D.1
Chatterjee, M.2
Borst, O.3
Muller, K.4
Stellos, K.5
Mack, A.F.6
-
214
-
-
78650956554
-
CXCR4 and CXCR7 have distinct functions in regulating interneuron migration
-
Wang Y, Li G, Stanco A, Long JE, Crawford D, Potter GB, et al. CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Neuron (2011) 69:61-76. doi:10.1016/j.neuron.2010.12.005.
-
(2011)
Neuron
, vol.69
, pp. 61-76
-
-
Wang, Y.1
Li, G.2
Stanco, A.3
Long, J.E.4
Crawford, D.5
Potter, G.B.6
-
215
-
-
83955163771
-
CXCR7 mediated Gialpha independent activation of ERK and Akt promotes cell survival and chemotaxis in T cells
-
Kumar R, Tripathi V, Ahmad M, Nath N, Mir RA, Chauhan SS, et al. CXCR7 mediated Gialpha independent activation of ERK and Akt promotes cell survival and chemotaxis in T cells. Cell Immunol (2012) 272:230-41. doi:10.1016/j.cellimm.2011.09.015.
-
(2012)
Cell Immunol
, vol.272
, pp. 230-241
-
-
Kumar, R.1
Tripathi, V.2
Ahmad, M.3
Nath, N.4
Mir, R.A.5
Chauhan, S.S.6
-
216
-
-
84937630636
-
CXCR7 mediates neural progenitor cells migration to CXCL12 independent of CXCR4
-
Chen Q, Zhang M, Li Y, Xu D, Wang Y, Song A, et al. CXCR7 mediates neural progenitor cells migration to CXCL12 independent of CXCR4. Stem Cells (2015) 33(8):2574-85. doi:10.1002/stem.2022.
-
(2015)
Stem Cells
, vol.33
, Issue.8
, pp. 2574-2585
-
-
Chen, Q.1
Zhang, M.2
Li, Y.3
Xu, D.4
Wang, Y.5
Song, A.6
-
217
-
-
84856227953
-
The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells
-
Ödemis V, Lipfert J, Kraft R, Hajek P, Abraham G, Hattermann K, et al. The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells. Glia (2012) 60:372-81. doi:10.1002/glia.22271.
-
(2012)
Glia
, vol.60
, pp. 372-381
-
-
Ödemis, V.1
Lipfert, J.2
Kraft, R.3
Hajek, P.4
Abraham, G.5
Hattermann, K.6
-
218
-
-
84858784275
-
Ubiquitination of CXCR7 controls receptor trafficking
-
Canals M, Scholten DJ, De Munnik S, Han MK, Smit MJ, Leurs R. Ubiquitination of CXCR7 controls receptor trafficking. PLoS One (2012) 7:e34192. doi:10.1371/journal.pone.0034192.
-
(2012)
PLoS One
, vol.7
-
-
Canals, M.1
Scholten, D.J.2
De Munnik, S.3
Han, M.K.4
Smit, M.J.5
Leurs, R.6
-
219
-
-
67650349084
-
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
-
Levoye A, Balabanian K, Baleux F, Bachelerie F, Lagane B. CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling. Blood (2009) 113:6085-93. doi:10.1182/blood-2008-12-196618.
-
(2009)
Blood
, vol.113
, pp. 6085-6093
-
-
Levoye, A.1
Balabanian, K.2
Baleux, F.3
Bachelerie, F.4
Lagane, B.5
-
220
-
-
77955657351
-
Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands
-
Luker KE, Steele JM, Mihalko LA, Ray P, Luker GD. Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands. Oncogene (2010) 29:4599-610. doi:10.1038/onc.2010.212.
-
(2010)
Oncogene
, vol.29
, pp. 4599-4610
-
-
Luker, K.E.1
Steele, J.M.2
Mihalko, L.A.3
Ray, P.4
Luker, G.D.5
-
221
-
-
84896713600
-
The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets
-
Puchert M, Engele J. The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets. Cell Tissue Res (2014) 355:239-53. doi:10.1007/s00441-013-1747-y.
-
(2014)
Cell Tissue Res
, vol.355
, pp. 239-253
-
-
Puchert, M.1
Engele, J.2
-
222
-
-
84903740197
-
SDF-1alpha induces differential trafficking of CXCR4-CXCR7 involving cyclophilin A, CXCR7 ubiquitination and promotes platelet survival
-
Chatterjee M, Seizer P, Borst O, Schonberger T, Mack A, Geisler T, et al. SDF-1alpha induces differential trafficking of CXCR4-CXCR7 involving cyclophilin A, CXCR7 ubiquitination and promotes platelet survival. FASEB J (2014) 28:2864-78. doi:10.1096/fj.14-249730.
-
(2014)
FASEB J
, vol.28
, pp. 2864-2878
-
-
Chatterjee, M.1
Seizer, P.2
Borst, O.3
Schonberger, T.4
Mack, A.5
Geisler, T.6
-
223
-
-
84892370936
-
Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
-
Ding BS, Cao Z, Lis R, Nolan DJ, Guo P, Simons M, et al. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature (2014) 505:97-102. doi:10.1038/nature12681.
-
(2014)
Nature
, vol.505
, pp. 97-102
-
-
Ding, B.S.1
Cao, Z.2
Lis, R.3
Nolan, D.J.4
Guo, P.5
Simons, M.6
-
224
-
-
0032526864
-
Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
-
Cole KE, Strick CA, Paradis TJ, Ogborne KT, Loetscher M, Gladue RP, et al. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med (1998) 187:2009-21. doi:10.1084/jem.187.12.2009.
-
(1998)
J Exp Med
, vol.187
, pp. 2009-2021
-
-
Cole, K.E.1
Strick, C.A.2
Paradis, T.J.3
Ogborne, K.T.4
Loetscher, M.5
Gladue, R.P.6
-
225
-
-
0034144269
-
Chemokines: a new classification system and their role in immunity
-
Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity (2000) 12:121-7. doi:10.1016/S1074-7613(00)80165-X.
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
226
-
-
84861426163
-
The chemokine superfamily revisited
-
Zlotnik A, Yoshie O. The chemokine superfamily revisited. Immunity (2012) 36:705-16. doi:10.1016/j.immuni.2012.05.008.
-
(2012)
Immunity
, vol.36
, pp. 705-716
-
-
Zlotnik, A.1
Yoshie, O.2
-
227
-
-
84874252337
-
Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12
-
Singh AK, Arya RK, Trivedi AK, Sanyal S, Baral R, Dormond O, et al. Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12. Cytokine Growth Factor Rev (2013) 24:41-9. doi:10.1016/j.cytogfr.2012.08.007.
-
(2013)
Cytokine Growth Factor Rev
, vol.24
, pp. 41-49
-
-
Singh, A.K.1
Arya, R.K.2
Trivedi, A.K.3
Sanyal, S.4
Baral, R.5
Dormond, O.6
-
228
-
-
84898597743
-
Interaction of the chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the regulation of tumor angiogenesis of colorectal cancer
-
Rupertus K, Sinistra J, Scheuer C, Nickels RM, Schilling MK, Menger MD, et al. Interaction of the chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the regulation of tumor angiogenesis of colorectal cancer. Clin Exp Metastasis (2014) 31:447-59. doi:10.1007/s10585-014-9639-4.
-
(2014)
Clin Exp Metastasis
, vol.31
, pp. 447-459
-
-
Rupertus, K.1
Sinistra, J.2
Scheuer, C.3
Nickels, R.M.4
Schilling, M.K.5
Menger, M.D.6
-
229
-
-
84920195692
-
Macrophage migration inhibitory factor (MIF) limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling
-
Chatterjee M, Borst O, Walker B, Fotinos A, Vogel S, Seizer P, et al. Macrophage migration inhibitory factor (MIF) limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling. Circ Res (2014) 115:939-49. doi:10.1161/CIRCRESAHA.115.305171.
-
(2014)
Circ Res
, vol.115
, pp. 939-949
-
-
Chatterjee, M.1
Borst, O.2
Walker, B.3
Fotinos, A.4
Vogel, S.5
Seizer, P.6
-
230
-
-
0033986413
-
A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses
-
Shimizu N, Soda Y, Kanbe K, Liu HY, Mukai R, Kitamura T, et al. A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses. J Virol (2000) 74:619-26. doi:10.1128/JVI.74.2.619-626.2000.
-
(2000)
J Virol
, vol.74
, pp. 619-626
-
-
Shimizu, N.1
Soda, Y.2
Kanbe, K.3
Liu, H.Y.4
Mukai, R.5
Kitamura, T.6
-
231
-
-
84894446453
-
Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection
-
Chevigné A, Fievez V, Szpakowska M, Fischer A, Counson M, Plesséria J-M, et al. Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection. Biochim Biophys Acta (2014) 1843:1031-41. doi:10.1016/j.bbamcr.2014.01.017.
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 1031-1041
-
-
Chevigné, A.1
Fievez, V.2
Szpakowska, M.3
Fischer, A.4
Counson, M.5
Plesséria, J.-M.6
-
232
-
-
0037656291
-
Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
-
Hernandez PA, Gorlin RJ, Lukens JN, Taniuchi S, Bohinjec J, Francois F, et al. Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. Nat Genet (2003) 34:70-4. doi:10.1038/ng1149.
-
(2003)
Nat Genet
, vol.34
, pp. 70-74
-
-
Hernandez, P.A.1
Gorlin, R.J.2
Lukens, J.N.3
Taniuchi, S.4
Bohinjec, J.5
Francois, F.6
-
233
-
-
84924308992
-
New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities
-
Poty S, Desogere P, Goze C, Boschetti F, D'huys T, Schols D, et al. New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities. Dalton Trans (2015) 44:5004-16. doi:10.1039/c4dt02972k.
-
(2015)
Dalton Trans
, vol.44
, pp. 5004-5016
-
-
Poty, S.1
Desogere, P.2
Goze, C.3
Boschetti, F.4
D'huys, T.5
Schols, D.6
-
234
-
-
0025123316
-
A new familial immunodeficiency disorder characterized by severe neutropenia, a defective marrow release mechanism, and hypogammaglobulinemia
-
Wetzler M, Talpaz M, Kleinerman ES, King A, Huh YO, Gutterman JU, et al. A new familial immunodeficiency disorder characterized by severe neutropenia, a defective marrow release mechanism, and hypogammaglobulinemia. Am J Med (1990) 89:663-72. doi:10.1016/0002-9343(90)90187-I.
-
(1990)
Am J Med
, vol.89
, pp. 663-672
-
-
Wetzler, M.1
Talpaz, M.2
Kleinerman, E.S.3
King, A.4
Huh, Y.O.5
Gutterman, J.U.6
-
235
-
-
84922758305
-
Chromothriptic cure of WHIM syndrome
-
McDermott DH, Gao J-L, Liu Q, Siwicki M, Martens C, Jacobs P, et al. Chromothriptic cure of WHIM syndrome. Cell (2015) 160:686-99. doi:10.1016/j.cell.2015.01.014.
-
(2015)
Cell
, vol.160
, pp. 686-699
-
-
McDermott, D.H.1
Gao, J.-L.2
Liu, Q.3
Siwicki, M.4
Martens, C.5
Jacobs, P.6
-
236
-
-
84883176178
-
CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential
-
Wald O. CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential. Theranostics (2013) 3:26-33. doi:10.7150/thno.4922.
-
(2013)
Theranostics
, vol.3
, pp. 26-33
-
-
Wald, O.1
-
237
-
-
58249100053
-
CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
-
Burger JA, Peled A. CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers. Leukemia (2008) 23:43-52. doi:10.1038/leu.2008.299.
-
(2008)
Leukemia
, vol.23
, pp. 43-52
-
-
Burger, J.A.1
Peled, A.2
-
238
-
-
0344823964
-
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
-
Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, et al. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Natl Acad Sci U S A (2003) 100:13513-8. doi:10.1073/pnas.2235846100.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13513-13518
-
-
Rubin, J.B.1
Kung, A.L.2
Klein, R.S.3
Chan, J.A.4
Sun, Y.5
Schmidt, K.6
-
239
-
-
9344255481
-
Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
-
Abbott JD, Huang Y, Liu D, Hickey R, Krause DS, Giordano FJ. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation (2004) 110:3300-5. doi:10.1161/01.CIR.0000147780.30124.CF.
-
(2004)
Circulation
, vol.110
, pp. 3300-3305
-
-
Abbott, J.D.1
Huang, Y.2
Liu, D.3
Hickey, R.4
Krause, D.S.5
Giordano, F.J.6
-
240
-
-
77950574556
-
Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury
-
Chen J, Chemaly E, Liang L, Kho C, Lee A, Park J, et al. Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury. Am J Pathol (2010) 176:1705-15. doi:10.2353/ajpath.2010.090451.
-
(2010)
Am J Pathol
, vol.176
, pp. 1705-1715
-
-
Chen, J.1
Chemaly, E.2
Liang, L.3
Kho, C.4
Lee, A.5
Park, J.6
-
241
-
-
81855225283
-
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction
-
Liehn EA, Tuchscheerer N, Kanzler I, Drechsler M, Fraemohs L, Schuh A, et al. Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol (2011) 58:2415-23. doi:10.1016/j.jacc.2011.08.033.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 2415-2423
-
-
Liehn, E.A.1
Tuchscheerer, N.2
Kanzler, I.3
Drechsler, M.4
Fraemohs, L.5
Schuh, A.6
-
242
-
-
84883300963
-
Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion
-
Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sonmez TT, et al. Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion. Arterioscler Thromb Vasc Biol (2013) 33:2180-6. doi:10.1161/ATVBAHA.113.301633.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2180-2186
-
-
Liehn, E.A.1
Kanzler, I.2
Konschalla, S.3
Kroh, A.4
Simsekyilmaz, S.5
Sonmez, T.T.6
-
243
-
-
84924907194
-
The role of macrophage migration inhibitory factor in critical illness
-
Rex S, Kraemer S, Grieb G, Emontzpohl C, Soppert J, Goetzenich A, et al. The role of macrophage migration inhibitory factor in critical illness. Mini Rev Med Chem (2014) 14:1116-24.
-
(2014)
Mini Rev Med Chem
, vol.14
, pp. 1116-1124
-
-
Rex, S.1
Kraemer, S.2
Grieb, G.3
Emontzpohl, C.4
Soppert, J.5
Goetzenich, A.6
-
245
-
-
77954086292
-
Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells
-
Pusic I, Dipersio JF. Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells. Curr Opin Hematol (2010) 17:319-26. doi:10.1097/MOH.0b013e328338b7d5.
-
(2010)
Curr Opin Hematol
, vol.17
, pp. 319-326
-
-
Pusic, I.1
Dipersio, J.F.2
-
246
-
-
84937432800
-
CXCR4 antagonist TG-0054 mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction
-
Hsu W-T, Jui H-Y, Huang Y-H, Su M-YM, Wu Y-W, Tseng W-YI, et al. CXCR4 antagonist TG-0054 mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction. Cell Transplant (2014) 24:1313-28. doi:10.3727/096368914X681739.
-
(2014)
Cell Transplant
, vol.24
, pp. 1313-1328
-
-
Hsu, W.-T.1
Jui, H.-Y.2
Huang, Y.-H.3
Su, M.-Y.M.4
Wu, Y.-W.5
Tseng, W.-Y.I.6
-
247
-
-
23044456806
-
AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor
-
Hatse S, Princen K, De Clercq E, Rosenkilde MM, Schwartz TW, Hernandez-Abad PE, et al. AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. Biochem Pharmacol (2005) 70:752-61. doi:10.1016/j.bcp.2005.05.035.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 752-761
-
-
Hatse, S.1
Princen, K.2
De Clercq, E.3
Rosenkilde, M.M.4
Schwartz, T.W.5
Hernandez-Abad, P.E.6
-
248
-
-
66049128598
-
AMD3100 is a CXCR7 ligand with allosteric agonist properties
-
Kalatskaya I, Berchiche YA, Gravel S, Limberg BJ, Rosenbaum JS, Heveker N. AMD3100 is a CXCR7 ligand with allosteric agonist properties. Mol Pharmacol (2009) 75:1240-7. doi:10.1124/mol.108.053389.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1240-1247
-
-
Kalatskaya, I.1
Berchiche, Y.A.2
Gravel, S.3
Limberg, B.J.4
Rosenbaum, J.S.5
Heveker, N.6
-
249
-
-
20244375128
-
SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells
-
Zernecke A, Schober A, Bot I, Von Hundelshausen P, Liehn EA, Mopps B, et al. SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells. Circ Res (2005) 96:784-91. doi:10.1161/01.RES.0000162100.52009.38.
-
(2005)
Circ Res
, vol.96
, pp. 784-791
-
-
Zernecke, A.1
Schober, A.2
Bot, I.3
Von Hundelshausen, P.4
Liehn, E.A.5
Mopps, B.6
-
250
-
-
84901495097
-
Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice
-
Noels H, Zhou B, Tilstam PV, Theelen W, Li X, Pawig L, et al. Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice. Arterioscler Thromb Vasc Biol (2014) 34:1209-20. doi:10.1161/ATVBAHA.113.302878.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 1209-1220
-
-
Noels, H.1
Zhou, B.2
Tilstam, P.V.3
Theelen, W.4
Li, X.5
Pawig, L.6
|