Crystal structure at 2.6-Å resolution of human macrophage migration inhibitory factor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 11, 1996, Pages 5191-5196

  Sun, Hong Wei ^a   Bernhagen, Jurgen ^b,c   Bucala, Richard ^b   Lolis, Elias ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PICOWER INST FOR MEDICAL RESEARCH   (United States)

^c FRAUNHOFER INSTITUTE FOR INTERFACIAL ENGINEERING AND BIOTECHNOLOGY IGB   (Germany)

Author keywords

Cytokine; Glucocorticoid; Protein structure; Sepsis

Indexed keywords

CYTOKINE; GLUCOCORTICOID; MACROPHAGE MIGRATION INHIBITION FACTOR; PROTEIN SUBUNIT;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; LEUKOCYTE MIGRATION; MACROPHAGE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN ISOLATION;

AMINO ACID SEQUENCE; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HUMANS; MACROMOLECULAR SUBSTANCES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MODELS, MOLECULAR; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS;

EID: 0029895838     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.11.5191     Document Type: Article

References (44)

1. Bernhagen, J., Calandra, T., Mitchell, R. A., Martin, S. B., Tracey, K. J., Voelter, W., Manogue, K. R., Cerami, A. & Bucala, R. (1993) Nature (London) 365, 756-759.
2. Calandra, T., Bernhagen, J., Mitchell, R. A. & Bucala, R. (1994) J. Exp. Med 179, 1895-1902.
3. Galat, A., Riviere, S., Bouet, F. & Menez, A. (1994) Eur. J. Biochem. 224, 417-421.
4. Wistow, G., Shaughness, M., Lee, D., Hodin, J. & Zelenka, P. (1993) Proc. Natl. Acad. Sci. USA 90, 1272-1275.
5. David, J. R. (1966) Proc. Natl. Acad. Sci. USA 56, 72-77.
6. Bloom, B. R. & Bennett, B. (1966) Science 153, 80-82.
7. Nishino, T., Bernhagen, J., Shliki, H., Calandra, T., Dohl, K. & Bucala, R. (1995) Mol. Med. 1, 781-788.
8. Calandra, T., Bernhagen, J., Metz, C. N., Spiegel, L., Bacher, M., Donnelly, T., Cerami, A. & Bucala, R. (1995) Nature (London) 377, 68-71.
9. Blocki, F., Schlievert, P. & Wackett, L. (1992) Nature (London) 360, 269-270.
10. Rosengren, E., Bucala, R., Arnan, P., Jacobsson, L., Odh, G., Metz, C. N. & Rorsman, H. (1996) Mol. Med. 2, 143-149.
11. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Laboratory Press, Plainview, NY), 2nd Ed.
12. Suzuki, M., Murata, E. & Tanaka, I. (1994) J. Mol. Biol. 235, 1141-1143.
13. Kabsch, W. (1993) J. Appl. Crystallogr. 26, 795-800.
14. Sheldrick, G. M. (1990) Acta Crystallogr. A 46, 467-473.
15. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
16. Brunger, A. T. (1992) XPLOR Manual (The Howard Hughes Medical Institute and Department of Biophysics and Biochemistry, Yale University, New Haven, CT), version 3.1.
17. Holm, L. & Sander, C. (1993) J. Mol. Biol. 233, 123-138.
18. Connolly, M. L. (1983) Science 221, 709-813.
19. Richards, F. M. (1974) J. Mol. Biol. 82, 1-14.
20. Nishihara, J., Kuriyama, T., Sakai, M., Nishi, S., Ohki, S.-Y. & Hikichi, K. (1995) Biochim. Biophys. Acta 1247, 159-162.
21. Bernhagen, J., Mitchell, R. A., Calandra, T., Voelter, W., Cerami, A. & Bucala, R. (1994) Biochemistry 33, 14144-14155.
22. Baldwin, E. T., Weber, I. T., St. Charles, R., Xuan, J.-C., Apella, E., Yamanda, M., Matsushima, K., Edwards, B. F. P., Clore, G. M., Gronenborn, A. M. & Wlodower, A. (1991) Proc. Natl. Acad. Sci. USA 88, 502-506.
23. Bernhagen, J., Kapurniotu, A., Stoeva, S., Voelter, W. & Bucala, R. (1995) in Peptides 1994, ed. Maia, H. L. S. (ESCOM, Leiden), pp. 572-573.
24. Hubbard, S., Gross, K. & Argos, P. (1994) Protein Eng. 7, 613-626.
25. Kisljuk, O., Kachalova, G. & Lanina, N. (1994) J. Mol. Graphics 196, 305-307.
26. Braig, K., Otwinowski, Z., Hegde, R., Boisvert, D. C., Joachimiak, A., Horwich, A. L. & Sigler, P. B. (1994) Nature (London) 371, 578-586.
27. Kong, X. P., Onrust, R., O'Donnell, M. & Kuriyan, J. (1992) Cell 69, 425-437.
28. Schirmer, T., Keller, T. A., Wang, Y.-F. & Rosenbusch, J. P. (1995) Science 267, 512-514.
29. Weiss, M. S. & Schulz, G. E. (1992) J. Mol. Biol. 227, 493-509.
30. Bilwes, A., Rees, B., Moras, D., Menez, R. & Menez, A. (1994) J. Mol. Biol. 239, 1122-1136.
31. Xiao, B., Smerdon, S. J., Jones, D. H., Dodson, G. G., Soneji, Y., Altken, A. & Gamblin, S. J. (1995) Nature (London) 376, 188-191.
32. Liu, D. Y., David, J. R. & Remold, H. G. (1982) Nature (London) 296, 78-80.
33. Zhang, M., Aman, P., Grubb, A., Panagiopoulos, I., Hindemith, A., Rosengren, E. & Rorsman, H. (1995) FEBS Lett. 373, 203-206.
34. Blocki, F. A., Ellis, L. B. & Wackett, L. P. (1993) Protein Sci. 2, 2095-2102.
35. Pearson, W. R. (1994) Protein Sci. 3, 525-527.
36. Sakai, M., Nishihara, J., Hibiya, Y., Koyama, Y. & Nishi, S. (1994) Biochem. Mol. Biol. Intl. 33, 439-446.
37. Gulick, A. M. & Fahl, W. E. (1995) Pharmacol. Ther. 66, 237-257.
38. Sinning, I., Kleywegt, G. J., Cowan, S. W., Reinemer, P., Dirr, H. W., Huber, R., Gilliland, G. L., Armstrong, R. N., Ji, X., Board, P. G., Olin, B., Mannervik, B. & Jones, T. A. (1993) J. Mol. Biol. 232, 192-212.
39. Ji, X., Zhang, P., Armstrong, R. N. & Gilliland, G. L. (1992) Biochemistry 31, 10169-84.
40. Reinemer, P., Dirr, H. W., Ladenstein, R., Schaffer, J., Gallay, O. & Huber, R. (1991) EMBO J. 10, 1997-2005.
41. Ji, X., von Rosenvinge, E. C., Johnson, W. W., Tomarev, S. I., Piatigorsky, J., Armstrong, R. N. & Gilliland, G. L. (1995) Biochemistry 34, 5317-28.
42. Reinemer, P., Dirr, H. W., Ladenstein, R. & Huber, R. (1992) J. Mol. Biol. 277, 214-226.
43. Lasters, I., Wodak, S. J., Alard, P. & van Cutsem, E. (1988) Proc. Natl. Acad. Sci. USA 85, 3338-3342.
44. Sun, H. W., Swope, M., Cinquina, C., Bedarkar, S., Bernhagen, J., Bucala, R. & Lolis, E. (1996) Protein Eng., in press.