Stromal cell-derived factor-1α plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury

Circulation

Volumn 110, Issue 21, 2004, Pages 3300-3305

  Abbott, J Dawn ^a   Huang, Yan ^a   Liu, Dingang ^a   Hickey, Reed ^a   Krause, Diane S ^a   Giordano, Frank J ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BCMM 439 ^*  (United States)

Author keywords

Cell adhesion molecules; Cells; Growth factors; Myocardial infarction

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ADENOVIRUS VECTOR; CELL ADHESION MOLECULE; CHEMOKINE RECEPTOR CXCR4; GROWTH FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CHEMOTAXIS; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG ANTAGONISM; FEMALE; GENE; GENE EXPRESSION; HEART INFARCTION; HEART INJURY; HEART MUSCLE; ICAM 1 GENE; IN VIVO STUDY; MMP 9 GENE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE POLYMERASE CHAIN REACTION; SDF 1 GENE; STEM CELL; VCAM 1 GENE; VEGF GENE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL LINEAGE; CELL MOVEMENT; CHEMOKINES, CXC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE THERAPY; HETEROCYCLIC COMPOUNDS; INTERCELLULAR ADHESION MOLECULE-1; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED NOD; MICE, SCID; MYOCARDIAL INFARCTION; MYOCARDIUM; RECEPTORS, CXCR4; RECOMBINANT FUSION PROTEINS; STEM CELL TRANSPLANTATION; STEM CELLS; TRANSDUCTION, GENETIC; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 9344255481     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000147780.30124.CF     Document Type: Article

References (32)

1. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature. 2001;410:701-705.
2. Balsam LB, Wagers AJ, Christensen JL, et al. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature. 2004;428:668-673.
3. Murry CE, Soonpaa MH, Reinecke H, et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature. 2004;428:664-668.
4. Rehman J, Li J, Orschell CM, et al. Peripheral blood 'endothelial progenitor cells' are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation. 2003;107:1164-1169.
5. Perin EC, Dohmann HF, Borojevic R, et al. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemie heart failure [comment]. Circulation. 2003;107:2294-2302.
6. Assmus B, Schachinger V, Teupe C, et al. Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI). Circulation. 2002;106:3009-3017.
7. Shintani S, Murohara T, Ikeda H, et al. Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation. 2001;103:2776-2779.
8. + endothelial precursor cells. Circ Res. 2001;88:167-174.
9. Jackson KA, Majka SM, Wang H, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001;107:1395-1402.
10. Kawamoto A, Gwon HC, Iwaguro H, et al. Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation. 2001;103:634-637.
11. Yeh ET, Zhang S, Wu H, et al. Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation. 2003;108:2070-2074.
12. Peled A, Petit I, Kollet O, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science. 1999;283:845-848.
13. Kollet O, Shivtiel S, Chen YQ, et al. HGF, SDF-I, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. J Clin Invest. 2003;112:160-169.
14. Schober A, Knarren S, Lietz M, et al. Crucial role of stromal cell-derived factor-1α in neointima formation after vascular injury in apolipoprotein E-deficient mice. Circulation. 2003;108:2491-2497.
15. Abi-Younes S, Sauty A, Mach F, et al. The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques. Circ Res. 2000;86:131-138.
16. Damas JK, Waehre T, Yndestad A, et al. Stromal cell-derived factor-1α in unstable angina: potential antiinflammatory and matrix-stabilizing effects. Circulation. 2002;106:36-42.
17. Askari AT, Unzek S, Popovic ZB, et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy [comment]. Lancet. 2003;362:697-703.
18. Kang HJ, Kim HS, Zhang SY, et al. Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial. Lancet. 2004;363:751-756.
19. Yamaguchi J, Kusano KF, Masuo O, et al. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation. 2003;107:1322-1328.
20. Giordano FJ, Ping P, McKirnan MD, et al. Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart [comment]. Nat Med. 1996;2:534-539.
21. Chen J, Kubalak SW, Minamisawa S, et al. Selective requirement of myosin light chain 2v in embryonic heart function. J Biol Chem. 1998;273:1252-1256.
22. Hatse S, Princen K, Bridger G, et al. Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4. FEBS Lett. 2002:527:255-262.
23. Vermeulen M, Le Pesteur F, Gagnerault MC, et al. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood. 1998:92:894-900.
24. Frenette PS, Subbarao S, Mazo IB, et al. Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow [comment]. Proc Natl Acad Sci USA. 1998;95:14423-14428.
25. Peled A, Grabovsky V, Habler L, et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow. J Clin Invest. 1999;104:1199-1211.
26. Mohle R, Rafii S, Moore MA. The role of endothelium in the regulation of hematopoietic stem cell migration. Stem Cells. 1998:16:159-165.
27. Loetscher M, Geiser T, O'Reilly T, et al. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes. J Biol Chem. 1994;269:232-237.
28. Petit I, Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 [erratum appears in Nat Immunol. 2002;3:787]. Nat Immunol. 2002;3:687-694.
29. Petit I, Szyper-Kravitz M, Nagler A, et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 [erratum appears in Nat Immunol. 2002;3:787]. Nat Immunol. 2002;3:687-694.
30. McQuibban GA, Butler GS, Gong JH, et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem. 2001;276:43503-43508.
31. Kai H, Ikeda H, Yasukawa H, et al. Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. J Am Coll Cardiol. 1998;32:368-372.
32. Heissig B, Hattori K, Dias S, et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell. 2002;109:625-637.