메뉴 건너뛰기




Volumn 118, Issue 6, 2008, Pages 2050-2061

p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CYCLIN DEPENDENT KINASE INHIBITOR 1; JANUS KINASE; STAT PROTEIN; STAT3 PROTEIN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN P53; STROMAL CELL DERIVED FACTOR 1;

EID: 45749105047     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI31244     Document Type: Article
Times cited : (51)

References (66)
  • 1
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. 2002. Inflammation in atherosclerosis. Nature. 420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 2
    • 0036852824 scopus 로고    scopus 로고
    • Innate and acquired immunity in atherogenesis
    • Binder, C.J., et al. 2002. Innate and acquired immunity in atherogenesis. Nat. Med. 8:1218-1226.
    • (2002) Nat. Med , vol.8 , pp. 1218-1226
    • Binder, C.J.1
  • 3
    • 0036105149 scopus 로고    scopus 로고
    • Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis
    • Sata, M., et al. 2002. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat. Med. 8:403-409.
    • (2002) Nat. Med , vol.8 , pp. 403-409
    • Sata, M.1
  • 4
    • 4043148770 scopus 로고    scopus 로고
    • Bone marrow-derived immune cells regulate vascular disease through a p27(Kip1)-dependent mechanism
    • Boehm, M., et al. 2004. Bone marrow-derived immune cells regulate vascular disease through a p27(Kip1)-dependent mechanism. J. Clin. Invest. 114:419-426.
    • (2004) J. Clin. Invest , vol.114 , pp. 419-426
    • Boehm, M.1
  • 5
    • 30344437303 scopus 로고    scopus 로고
    • VEGF-induced adult neovascularization: Recruitment, retention, and role of accessory cells
    • Grunewald, M., et al. 2006. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell. 124:175-189.
    • (2006) Cell , vol.124 , pp. 175-189
    • Grunewald, M.1
  • 6
    • 16444362796 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 increases CXCR4 expression, stromal-derived factor-1alpha-stimulated signalling and human immunodeficiency virus-1 entry in human monocyte derived macrophages
    • Chen, S., et al. 2005. Transforming growth factor-beta1 increases CXCR4 expression, stromal-derived factor-1alpha-stimulated signalling and human immunodeficiency virus-1 entry in human monocyte derived macrophages. Immunology. 114:565-574.
    • (2005) Immunology , vol.114 , pp. 565-574
    • Chen, S.1
  • 9
    • 0033209897 scopus 로고    scopus 로고
    • The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
    • Vila-Coro, A.J., et al. 1999. The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J. 13:1699-1710.
    • (1999) FASEB J , vol.13 , pp. 1699-1710
    • Vila-Coro, A.J.1
  • 10
    • 0030806322 scopus 로고    scopus 로고
    • Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell-derived factor 1alpha activation of Gi2 are differentially expressed in vivo
    • Moepps, B., et al. 1997. Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell-derived factor 1alpha activation of Gi2 are differentially expressed in vivo. Eur. J. Immunol. 27:2102-2112.
    • (1997) Eur. J. Immunol , vol.27 , pp. 2102-2112
    • Moepps, B.1
  • 11
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C.J., and Roberts, J.M. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 12
    • 8644219655 scopus 로고    scopus 로고
    • Living with or without cyclins and cyclin-dependent kinases
    • Sherr, C.J., and Roberts, J.M. 2004. Living with or without cyclins and cyclin-dependent kinases. Genes Dev. 18:2699-2711.
    • (2004) Genes Dev , vol.18 , pp. 2699-2711
    • Sherr, C.J.1    Roberts, J.M.2
  • 13
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry, W.S., et al. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell. 75:817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • el-Deiry, W.S.1
  • 14
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • Gu, Y., Turck, C.W., and Morgan, D.O. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature. 366:707-710.
    • (1993) Nature , vol.366 , pp. 707-710
    • Gu, Y.1    Turck, C.W.2    Morgan, D.O.3
  • 15
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K., and Elledge, S.J. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 16
    • 0027717617 scopus 로고
    • p21 is a universal inhibitor of cyclin kinases
    • Xiong, Y., et al. 1993. p21 is a universal inhibitor of cyclin kinases. Nature. 366:701-704.
    • (1993) Nature , vol.366 , pp. 701-704
    • Xiong, Y.1
  • 17
    • 0032572789 scopus 로고    scopus 로고
    • Resistance to Fas-mediated apoptosis: Activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP
    • Suzuki, A., Tsutomi, Y., Akahane, K., Araki, T., and Miura, M. 1998. Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP. Oncogene. 17:931-939.
    • (1998) Oncogene , vol.17 , pp. 931-939
    • Suzuki, A.1    Tsutomi, Y.2    Akahane, K.3    Araki, T.4    Miura, M.5
  • 18
    • 0033559264 scopus 로고    scopus 로고
    • The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
    • Cheng, M., et al. 1999. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1571-1583.
    • (1999) EMBO J , vol.18 , pp. 1571-1583
    • Cheng, M.1
  • 19
    • 0030973878 scopus 로고    scopus 로고
    • New functional activities for the p21 family of CDK inhibitors
    • LaBaer, J., et al. 1997. New functional activities for the p21 family of CDK inhibitors. Genes Dev. 11:847-862.
    • (1997) Genes Dev , vol.11 , pp. 847-862
    • LaBaer, J.1
  • 20
    • 0037126303 scopus 로고    scopus 로고
    • Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • Seoane, J., Le, H.V., and Massague, J. 2002. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature. 419:729-734.
    • (2002) Nature , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massague, J.3
  • 21
    • 11144320344 scopus 로고    scopus 로고
    • Absence of p21Waf1/Cip1/Sdi1 modulates macrophage differentiation and inflammatory response and protects against atherosclerosis
    • Merched, A.J., and Chan, L. 2004. Absence of p21Waf1/Cip1/Sdi1 modulates macrophage differentiation and inflammatory response and protects against atherosclerosis. Circulation. 110:3830-3841.
    • (2004) Circulation , vol.110 , pp. 3830-3841
    • Merched, A.J.1    Chan, L.2
  • 22
    • 33646505131 scopus 로고    scopus 로고
    • p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis
    • Scatizzi, J.C., et al. 2006. p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. Am. J. Pathol. 168:1531-1541.
    • (2006) Am. J. Pathol , vol.168 , pp. 1531-1541
    • Scatizzi, J.C.1
  • 23
    • 0028815552 scopus 로고
    • Adenovirus-mediated overexpression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty
    • Chang, M.W., Barr, E., Lu, M.M., Barton, K., and Leiden, J.M. 1995. Adenovirus-mediated overexpression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J. Clin. Invest. 96:2260-2268.
    • (1995) J. Clin. Invest , vol.96 , pp. 2260-2268
    • Chang, M.W.1    Barr, E.2    Lu, M.M.3    Barton, K.4    Leiden, J.M.5
  • 24
    • 0034816303 scopus 로고    scopus 로고
    • Mutated p21/WAF/CIP transgene overexpression reduces smooth muscle cell proliferation, macrophage deposition, oxidation-sensitive mechanisms, and restenosis in hypercholesterolemic apolipoprotein E knockout mice
    • Condorelli, G., Aycock, J.K., Frati, G., and Napoli, C. 2001. Mutated p21/WAF/CIP transgene overexpression reduces smooth muscle cell proliferation, macrophage deposition, oxidation-sensitive mechanisms, and restenosis in hypercholesterolemic apolipoprotein E knockout mice. FASEB J. 15:2162-2170.
    • (2001) FASEB J , vol.15 , pp. 2162-2170
    • Condorelli, G.1    Aycock, J.K.2    Frati, G.3    Napoli, C.4
  • 25
    • 0036341148 scopus 로고    scopus 로고
    • Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway
    • Sata, M., et al. 2002. Mouse genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a p21(WAF1)-dependent pathway. Arterioscler. Thromb. Vasc. Biol. 22:1305-1309.
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 1305-1309
    • Sata, M.1
  • 26
    • 0029794891 scopus 로고    scopus 로고
    • Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury
    • Yang, Z.Y., et al. 1996. Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury. Proc. Natl. Acad. Sci. U. S. A. 93:7905-7910.
    • (1996) Proc. Natl. Acad. Sci. U. S. A , vol.93 , pp. 7905-7910
    • Yang, Z.Y.1
  • 27
    • 0034595296 scopus 로고    scopus 로고
    • Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation
    • Tanner, F.C., et al. 2000. Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation. Circulation. 101:2022-2025.
    • (2000) Circulation , vol.101 , pp. 2022-2025
    • Tanner, F.C.1
  • 28
    • 0344284580 scopus 로고    scopus 로고
    • Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
    • Otterbein, L.E., et al. 2003. Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat. Med. 9:183-190.
    • (2003) Nat. Med , vol.9 , pp. 183-190
    • Otterbein, L.E.1
  • 29
    • 0346336788 scopus 로고    scopus 로고
    • Selective inactivation of p27(Kip1) in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis
    • Diez-Juan, A., et al. 2004. Selective inactivation of p27(Kip1) in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis. Blood. 103:158-161.
    • (2004) Blood , vol.103 , pp. 158-161
    • Diez-Juan, A.1
  • 30
    • 0141765805 scopus 로고    scopus 로고
    • Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery
    • Moses, J.W., et al. 2003. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N. Engl. J. Med. 349:1315-1323.
    • (2003) N. Engl. J. Med , vol.349 , pp. 1315-1323
    • Moses, J.W.1
  • 31
    • 0035806921 scopus 로고    scopus 로고
    • Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model
    • Suzuki, T., et al. 2001. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation. 104:1188-1193.
    • (2001) Circulation , vol.104 , pp. 1188-1193
    • Suzuki, T.1
  • 32
    • 0038300674 scopus 로고    scopus 로고
    • Use of rapamycin slows progression of cardiac transplantation vasculopathy
    • Mancini, D., et al. 2003. Use of rapamycin slows progression of cardiac transplantation vasculopathy. Circulation. 108:48-53.
    • (2003) Circulation , vol.108 , pp. 48-53
    • Mancini, D.1
  • 33
    • 4043137360 scopus 로고    scopus 로고
    • Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model
    • Carter, A.J., et al. 2004. Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model. Cardiovasc. Res. 63:617-624.
    • (2004) Cardiovasc. Res , vol.63 , pp. 617-624
    • Carter, A.J.1
  • 34
    • 0036048524 scopus 로고    scopus 로고
    • Not just a CDK inhibitor: Regulation of transcription by p21(WAF1/CIP1/SDI1)
    • Perkins, N.D. 2002. Not just a CDK inhibitor: regulation of transcription by p21(WAF1/CIP1/SDI1). Cell Cycle. 1:39-41.
    • (2002) Cell Cycle , vol.1 , pp. 39-41
    • Perkins, N.D.1
  • 35
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret, O. 2003. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol. 13:65-70.
    • (2003) Trends Cell Biol , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 36
    • 0034616116 scopus 로고    scopus 로고
    • Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription
    • Kitaura, H., et al. 2000. Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription. J. Biol. Chem. 275:10477-10483.
    • (2000) J. Biol. Chem , vol.275 , pp. 10477-10483
    • Kitaura, H.1
  • 37
    • 0034705540 scopus 로고    scopus 로고
    • Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1
    • Coqueret, O., and Gascan, H. 2000. Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1. J. Biol. Chem. 275:18794-18800.
    • (2000) J. Biol. Chem , vol.275 , pp. 18794-18800
    • Coqueret, O.1    Gascan, H.2
  • 38
    • 0033598444 scopus 로고    scopus 로고
    • Control of E2F activity by p21Waf1/Cip1
    • Delavaine, L., and La Thangue, N.B. 1999. Control of E2F activity by p21Waf1/Cip1. Oncogene. 18:5381-5392.
    • (1999) Oncogene , vol.18 , pp. 5381-5392
    • Delavaine, L.1    La Thangue, N.B.2
  • 39
    • 0035800776 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding
    • Harris, T.E., Albrecht, J.H., Nakanishi, M., and Darlington, G.J. 2001. CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding. J. Biol. Chem. 276:29200-29209.
    • (2001) J. Biol. Chem , vol.276 , pp. 29200-29209
    • Harris, T.E.1    Albrecht, J.H.2    Nakanishi, M.3    Darlington, G.J.4
  • 40
    • 0032559554 scopus 로고    scopus 로고
    • Expression of cyclin-dependent kinase inhibitors in vascular disease
    • Tanner, F.C., et al. 1998. Expression of cyclin-dependent kinase inhibitors in vascular disease. Circ. Res. 82:396-403.
    • (1998) Circ. Res , vol.82 , pp. 396-403
    • Tanner, F.C.1
  • 41
    • 12144287287 scopus 로고    scopus 로고
    • p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization
    • Bruhl, T., et al. 2004. p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization. Circ. Res. 94:686-692.
    • (2004) Circ. Res , vol.94 , pp. 686-692
    • Bruhl, T.1
  • 42
    • 0142058957 scopus 로고    scopus 로고
    • Nitric oxide inhibits ischemia/reperfusion- induced myocardial apoptosis by modulating cyclin A-associated kinase activity
    • Maejima, Y., et al. 2003. Nitric oxide inhibits ischemia/reperfusion- induced myocardial apoptosis by modulating cyclin A-associated kinase activity. Cardiovasc. Res. 59:308-320.
    • (2003) Cardiovasc. Res , vol.59 , pp. 308-320
    • Maejima, Y.1
  • 43
    • 0042346348 scopus 로고    scopus 로고
    • Zhang, C., Kavurma, M.M., Lai, A., and Khachigian, L.M. 2003. Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter. J. Biol. Chem. 278:27903-27909.
    • Zhang, C., Kavurma, M.M., Lai, A., and Khachigian, L.M. 2003. Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting elements in the p21WAF/Cip1 promoter. J. Biol. Chem. 278:27903-27909.
  • 44
    • 20244365941 scopus 로고    scopus 로고
    • The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation
    • Beuvink, I., et al. 2005. The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation. Cell. 120:747-759.
    • (2005) Cell , vol.120 , pp. 747-759
    • Beuvink, I.1
  • 45
    • 0034959256 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects against vascular constriction and proliferation
    • Duckers, H.J., et al. 2001. Heme oxygenase-1 protects against vascular constriction and proliferation. Nat. Med. 7:693-698.
    • (2001) Nat. Med , vol.7 , pp. 693-698
    • Duckers, H.J.1
  • 46
    • 0031026475 scopus 로고    scopus 로고
    • The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
    • Aiuti, A., Webb, I.J., Bleul, C., Springer, T., and Gutierrez-Ramos, J.C. 1997. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J. Exp. Med. 185:111-120.
    • (1997) J. Exp. Med , vol.185 , pp. 111-120
    • Aiuti, A.1    Webb, I.J.2    Bleul, C.3    Springer, T.4    Gutierrez-Ramos, J.C.5
  • 47
    • 33845668020 scopus 로고    scopus 로고
    • Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease
    • Kovacic, J.C., Muller, D.W., and Graham, R.M. 2007. Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease. J. Mol. Cell. Cardiol. 42:19-33.
    • (2007) J. Mol. Cell. Cardiol , vol.42 , pp. 19-33
    • Kovacic, J.C.1    Muller, D.W.2    Graham, R.M.3
  • 48
    • 33646581046 scopus 로고    scopus 로고
    • Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes
    • Jin, D.K., et al. 2006. Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat. Med. 12:557-567.
    • (2006) Nat. Med , vol.12 , pp. 557-567
    • Jin, D.K.1
  • 49
    • 33846456223 scopus 로고    scopus 로고
    • M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: The critical role of the SDF-1-CXCR4 system
    • Shiba, Y., et al. 2007. M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system. Arterioscler. Thromb. Vasc. Biol. 27:283-289.
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , pp. 283-289
    • Shiba, Y.1
  • 50
    • 33845348208 scopus 로고    scopus 로고
    • p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts
    • Moskovits, N., Kalinkovich, A., Bar, J., Lapidot, T., and Oren, M. 2006. p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts. Cancer Res. 66:10671-10676.
    • (2006) Cancer Res , vol.66 , pp. 10671-10676
    • Moskovits, N.1    Kalinkovich, A.2    Bar, J.3    Lapidot, T.4    Oren, M.5
  • 51
    • 34249043939 scopus 로고    scopus 로고
    • Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: Implications of p53 mutation or isoform expression on breast cancer cell invasion
    • Mehta, S.A., et al. 2007. Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Oncogene. 26:3329-3337.
    • (2007) Oncogene , vol.26 , pp. 3329-3337
    • Mehta, S.A.1
  • 52
    • 23444449093 scopus 로고    scopus 로고
    • STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells
    • Jung, J.E., et al. 2005. STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells. FASEB J. 19:1296-1298.
    • (2005) FASEB J , vol.19 , pp. 1296-1298
    • Jung, J.E.1
  • 53
    • 0034616028 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes
    • Funamoto, M., et al. 2000. Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes. J. Biol. Chem. 275:10561-10566.
    • (2000) J. Biol. Chem , vol.275 , pp. 10561-10566
    • Funamoto, M.1
  • 54
    • 2142708560 scopus 로고    scopus 로고
    • The role of inflammation in vascular injury and repair
    • Davis, C., Fischer, J., Ley, K., and Sarembock, I.J. 2003. The role of inflammation in vascular injury and repair. J. Thromb. Haemost. 1:1699-1709.
    • (2003) J. Thromb. Haemost , vol.1 , pp. 1699-1709
    • Davis, C.1    Fischer, J.2    Ley, K.3    Sarembock, I.J.4
  • 55
    • 0033870765 scopus 로고    scopus 로고
    • Vascular cell apoptosis in remodeling, restenosis, and plaque rupture
    • Walsh, K., Smith, R.C., and Kim, H.S. 2000. Vascular cell apoptosis in remodeling, restenosis, and plaque rupture. Circ. Res. 87:184-188.
    • (2000) Circ. Res , vol.87 , pp. 184-188
    • Walsh, K.1    Smith, R.C.2    Kim, H.S.3
  • 56
    • 27644461772 scopus 로고    scopus 로고
    • Single perivascular delivery of mitomycin C stimulates p21 expression and inhibits neointima formation in rat arteries
    • Granada, J.F., et al. 2005. Single perivascular delivery of mitomycin C stimulates p21 expression and inhibits neointima formation in rat arteries. Arterioscler. Thromb. Vasc. Biol. 25:2343-2348.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 2343-2348
    • Granada, J.F.1
  • 57
    • 0030610836 scopus 로고    scopus 로고
    • p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene
    • Smith, R.C., et al. 1997. p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes Dev. 11:1674-1689.
    • (1997) Genes Dev , vol.11 , pp. 1674-1689
    • Smith, R.C.1
  • 58
    • 0038681342 scopus 로고    scopus 로고
    • The bicyclam AMD3100 story
    • De Clercq, E. 2003. The bicyclam AMD3100 story. Nat. Rev. Drug Discov. 2:581-587.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 581-587
    • De Clercq, E.1
  • 59
    • 19944432650 scopus 로고    scopus 로고
    • Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty
    • Nuhrenberg, T.G., et al. 2005. Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty. FASEB J. 19:246-248.
    • (2005) FASEB J , vol.19 , pp. 246-248
    • Nuhrenberg, T.G.1
  • 60
    • 17744387942 scopus 로고    scopus 로고
    • Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury
    • Togel, F., Isaac, J., Hu, Z., Weiss, K., and Westenfelder, C. 2005. Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury. Kidney Int. 67:1772-1784.
    • (2005) Kidney Int , vol.67 , pp. 1772-1784
    • Togel, F.1    Isaac, J.2    Hu, Z.3    Weiss, K.4    Westenfelder, C.5
  • 61
    • 85047690920 scopus 로고    scopus 로고
    • SDF-1 is both necessary and sufficient to promote proliferative retinopathy
    • Butler, J.M., et al. 2005. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. J. Clin. Invest. 115:86-93.
    • (2005) J. Clin. Invest , vol.115 , pp. 86-93
    • Butler, J.M.1
  • 62
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott, J.D., et al. 2004. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 110:3300-3305.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1
  • 63
    • 20244375128 scopus 로고    scopus 로고
    • SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells
    • Zernecke, A., et al. 2005. SDF-1alpha/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells. Circ. Res. 96:784-791.
    • (2005) Circ. Res , vol.96 , pp. 784-791
    • Zernecke, A.1
  • 64
    • 36348939263 scopus 로고    scopus 로고
    • Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice
    • Karshovska, E., et al. 2007. Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice. Arterioscler. Thromb. Vasc. Biol. 27:2540-2547.
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , pp. 2540-2547
    • Karshovska, E.1
  • 65
    • 6044254767 scopus 로고    scopus 로고
    • Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene
    • Giraud, S., Hurlstone, A., Avril, S., and Coqueret, O. 2004. Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene. Oncogene. 23:7391-7398.
    • (2004) Oncogene , vol.23 , pp. 7391-7398
    • Giraud, S.1    Hurlstone, A.2    Avril, S.3    Coqueret, O.4
  • 66
    • 23844503025 scopus 로고    scopus 로고
    • Role of Stat3 in regulating p53 expression and function
    • Niu, G., et al. 2005. Role of Stat3 in regulating p53 expression and function. Mol. Cell. Biol. 25:7432-7440.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 7432-7440
    • Niu, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.