-
1
-
-
0029758113
-
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
-
Nagasawa, T., S. Hirota, K. Tachibana, N. Takakura, S. Nishikawa, Y. Kitamura, N. Yoshida, H. Kikutani, and T. Kishimoto. 1996. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 382:635-638.
-
(1996)
Nature
, vol.382
, pp. 635-638
-
-
Nagasawa, T.1
Hirota, S.2
Tachibana, K.3
Takakura, N.4
Nishikawa, S.5
Kitamura, Y.6
Yoshida, N.7
Kikutani, H.8
Kishimoto, T.9
-
2
-
-
0032482926
-
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
-
Ma, Q., D. Jones, P.R. Borghesani, R.A. Segal, T. Nagasawa, T. Kishimoto, R.T. Bronson, and T.A. Springer. 1998. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl. Acad. Sci. USA. 95:9448-9453.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9448-9453
-
-
Ma, Q.1
Jones, D.2
Borghesani, P.R.3
Segal, R.A.4
Nagasawa, T.5
Kishimoto, T.6
Bronson, R.T.7
Springer, T.A.8
-
4
-
-
0032508033
-
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
-
Tachibana, K., S. Hirota, H. Iizasa, H. Yoshida, K. Kawabata, Y. Kataoka, Y. Kitamura, K. Matsushima, N. Yoshida, S. Nishikawa, et al. 1998. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature. 393:591-594.
-
(1998)
Nature
, vol.393
, pp. 591-594
-
-
Tachibana, K.1
Hirota, S.2
Iizasa, H.3
Yoshida, H.4
Kawabata, K.5
Kataoka, Y.6
Kitamura, Y.7
Matsushima, K.8
Yoshida, N.9
Nishikawa, S.10
-
5
-
-
0032948123
-
Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha
-
Salcedo, R., K. Wasserman, H.A. Young, M.C. Grimm, O.M. Howard, M.R. Anver, H.K. Kleinman, W.J. Murphy, and J.J. Oppenheim. 1999. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal-derived factor-1alpha. Am. J. Pathol. 154:1125-1135.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1125-1135
-
-
Salcedo, R.1
Wasserman, K.2
Young, H.A.3
Grimm, M.C.4
Howard, O.M.5
Anver, M.R.6
Kleinman, H.K.7
Murphy, W.J.8
Oppenheim, J.J.9
-
6
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul, C.C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, J. Sodroski, and T.A. Springer. 1996. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature. 382:829-832.
-
(1996)
Nature
, vol.382
, pp. 829-832
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
Parolin, C.4
Clark-Lewis, I.5
Sodroski, J.6
Springer, T.A.7
-
7
-
-
0032507962
-
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
-
Zou, Y.R., A.H. Kottmann, M. Kuroda, I. Taniuchi, and D.R. Littman. 1998. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature. 393:595-599.
-
(1998)
Nature
, vol.393
, pp. 595-599
-
-
Zou, Y.R.1
Kottmann, A.H.2
Kuroda, M.3
Taniuchi, I.4
Littman, D.R.5
-
8
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
-
Feng, Y., C.C. Broder, P.E. Kennedy, and E.A. Berger. 1996. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 272:872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.C.2
Kennedy, P.E.3
Berger, E.A.4
-
9
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
Oberlin, E., A. Amara, F. Bachelerie, C. Bessia, J.L. Virelizier, F. Arenzana-Seisdedos, O. Schwartz, J.M. Heard, I. Clark-Lewis, D.F. Legler, et al. 1996. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature. 382:833-835.
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.L.5
Arenzana-Seisdedos, F.6
Schwartz, O.7
Heard, J.M.8
Clark-Lewis, I.9
Legler, D.F.10
-
10
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller, A., B. Homey, H. Soto, N. Ge, D. Catron, M.E. Buchanan, T. McClanahan, E. Murphy, W. Yuan, S.N. Wagner, et al. 2001. Involvement of chemokine receptors in breast cancer metastasis. Nature. 410:50-56.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
-
11
-
-
0036830045
-
Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells
-
Kijima, T., G. Maulik, P.C. Ma, E.V. Tibaldi, R.E. Turner, B. Rollins, M. Sattler, B.E. Johnson, and R. Salgia. 2002. Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells. Cancer Res. 62:6304-6311.
-
(2002)
Cancer Res.
, vol.62
, pp. 6304-6311
-
-
Kijima, T.1
Maulik, G.2
Ma, P.C.3
Tibaldi, E.V.4
Turner, R.E.5
Rollins, B.6
Sattler, M.7
Johnson, B.E.8
Salgia, R.9
-
12
-
-
0036606772
-
CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma
-
Bertolini, F., C. Dell'Agnola, P. Mancuso, C. Rabascio, A. Burlini, S. Monestiroli, A. Gobbi, G. Pruneri, and G. Martinelli. 2002. CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma. Cancer Res. 62:3106-3112.
-
(2002)
Cancer Res.
, vol.62
, pp. 3106-3112
-
-
Bertolini, F.1
Dell'Agnola, C.2
Mancuso, P.3
Rabascio, C.4
Burlini, A.5
Monestiroli, S.6
Gobbi, A.7
Pruneri, G.8
Martinelli, G.9
-
13
-
-
0344823964
-
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
-
Rubin, J.B., A.L. Kung, R.S. Klein, J.A. Chan, Y. Sun, K. Schmidt, M.W. Kieran, A.D. Luster, and R.A. Segal. 2003. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc. Natl. Acad. Sci. USA. 100:13513-13518.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13513-13518
-
-
Rubin, J.B.1
Kung, A.L.2
Klein, R.S.3
Chan, J.A.4
Sun, Y.5
Schmidt, K.6
Kieran, M.W.7
Luster, A.D.8
Segal, R.A.9
-
14
-
-
33748456215
-
-
Inhibitors of human tumor-expressed CCX CKR2. Patent Cooperation Treaty application WO04058705 (15 July 2004) and USA patent publication US 20040170634 (2 September 2004)
-
Melikian, A., J. Burns, B.E. McMaster, T. Schall, and J.J. Wright. 2004. Inhibitors of human tumor-expressed CCX CKR2. Patent Cooperation Treaty application WO04058705 (15 July 2004) and USA patent publication US 20040170634 (2 September 2004).
-
(2004)
-
-
Melikian, A.1
Burns, J.2
McMaster, B.E.3
Schall, T.4
Wright, J.J.5
-
15
-
-
0037063329
-
Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4
-
Hatse, S., K. Princen, G. Bridger, E. De Clercq, and D. Schols. 2002. Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4. FEBS Lett. 527:255-262.
-
(2002)
FEBS Lett.
, vol.527
, pp. 255-262
-
-
Hatse, S.1
Princen, K.2
Bridger, G.3
De Clercq, E.4
Schols, D.5
-
16
-
-
0033618444
-
HHV8-encoded vMIP-I selectively engages chemokine receptor CCR8. Agonist and antagonist profiles of viral chemokines
-
Dairaghi, D.J., R.A. Fan, B.E. McMaster, M.R. Hanley, and T.J. Schall. 1999. HHV8-encoded vMIP-I selectively engages chemokine receptor CCR8. Agonist and antagonist profiles of viral chemokines. J. Biol. Chem. 274:21569-21574.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21569-21574
-
-
Dairaghi, D.J.1
Fan, R.A.2
McMaster, B.E.3
Hanley, M.R.4
Schall, T.J.5
-
17
-
-
15144349979
-
A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus
-
Kledal, T.N., M.M. Rosenkilde, F. Coulin, G. Simmons, A.H. Johnsen, S. Alouani, C.A. Power, H.R. Luttichau, J. Gerstoft, P.R. Clapham, et al. 1997. A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science. 277:1656-1659.
-
(1997)
Science
, vol.277
, pp. 1656-1659
-
-
Kledal, T.N.1
Rosenkilde, M.M.2
Coulin, F.3
Simmons, G.4
Johnsen, A.H.5
Alouani, S.6
Power, C.A.7
Luttichau, H.R.8
Gerstoft, J.9
Clapham, P.R.10
-
18
-
-
0032526864
-
Interferon-inducible T cell α chemoattractant (I-TAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
-
Cole, K.E., C.A. Strick, T.J. Paradis, K.T. Ogborne, M. Loetscher, R.P. Gladue, W. Lin, J.G. Boyd, B. Moser, D.E. Wood, et al. 1998. Interferon-inducible T cell α chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 187:2009-2021.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2009-2021
-
-
Cole, K.E.1
Strick, C.A.2
Paradis, T.J.3
Ogborne, K.T.4
Loetscher, M.5
Gladue, R.P.6
Lin, W.7
Boyd, J.G.8
Moser, B.9
Wood, D.E.10
-
19
-
-
0029829106
-
Chemokine receptor specific for IP10 and mig: Structure, function, and expression in activated T lymphocytes
-
Loetscher, M., B. Gerber, P. Loetscher, S.A. Jones, L. Piali, I. Clark-Lewis, M. Baggiolini, and B. Moser. 1996. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T lymphocytes. J. Exp. Med. 184:963-969.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 963-969
-
-
Loetscher, M.1
Gerber, B.2
Loetscher, P.3
Jones, S.A.4
Piali, L.5
Clark-Lewis, I.6
Baggiolini, M.7
Moser, B.8
-
20
-
-
0037126208
-
Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
-
RESEARCH0063
-
Joost, P., and A. Methner. 2002. Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biol. 3:RESEARCH0063.
-
(2002)
Genome Biol.
, vol.3
-
-
Joost, P.1
Methner, A.2
-
21
-
-
0025266746
-
Complete nucleotide sequence of a putative G protein coupled receptor: RDC1
-
Libert, F., M. Parmentier, A. Lefort, J.E. Dumont, and G. Vassart. 1990. Complete nucleotide sequence of a putative G protein coupled receptor: RDC1. Nucleic Acids Res. 18:1917.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 1917
-
-
Libert, F.1
Parmentier, M.2
Lefort, A.3
Dumont, J.E.4
Vassart, G.5
-
22
-
-
0031888981
-
Cloning and chromosomal mapping of an orphan chemokine receptor: Mouse RDC1
-
Heesen, M., M.A. Berman, A. Charest, D. Housman, C. Gerard, and M.E. Dorf. 1998. Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1. Immunogenetics. 47:364-370.
-
(1998)
Immunogenetics
, vol.47
, pp. 364-370
-
-
Heesen, M.1
Berman, M.A.2
Charest, A.3
Housman, D.4
Gerard, C.5
Dorf, M.E.6
-
23
-
-
3042644446
-
Vascular gene expression in nonneoplastic and malignant brain
-
Madden, S.L., B.P. Cook, M. Nacht, W.D. Weber, M.R. Callahan, Y. Jiang, M.R. Dufault, X. Zhang, W. Zhang, J. Walter-Yohrling, et al. 2004. Vascular gene expression in nonneoplastic and malignant brain. Am. J. Pathol. 165:601-608.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 601-608
-
-
Madden, S.L.1
Cook, B.P.2
Nacht, M.3
Weber, W.D.4
Callahan, M.R.5
Jiang, Y.6
Dufault, M.R.7
Zhang, X.8
Zhang, W.9
Walter-Yohrling, J.10
-
24
-
-
0036625019
-
Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow
-
Mazo, I.B., E.J. Quackenbush, J.B. Lowe, and U.H. von Andrian. 2002. Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow. Blood. 99:4182-4191.
-
(2002)
Blood
, vol.99
, pp. 4182-4191
-
-
Mazo, I.B.1
Quackenbush, E.J.2
Lowe, J.B.3
Von Andrian, U.H.4
-
25
-
-
0024345984
-
Selective amplification and cloning of four new members of the G protein-coupled receptor family
-
Libert, F., M. Parmentier, A. Lefort, C. Dinsart, J. Van Sande, C. Maenhaut, M.J. Simons, J.E. Dumont, and G. Vassart. 1989. Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science. 244:569-572.
-
(1989)
Science
, vol.244
, pp. 569-572
-
-
Libert, F.1
Parmentier, M.2
Lefort, A.3
Dinsart, C.4
Van Sande, J.5
Maenhaut, C.6
Simons, M.J.7
Dumont, J.E.8
Vassart, G.9
-
26
-
-
0025778145
-
Cloning and expression of the human vasoactive intestinal peptide receptor
-
Sreedharan, S.P., A. Robichon, K.E. Peterson, and E.J. Goetzl. 1991. Cloning and expression of the human vasoactive intestinal peptide receptor. Proc. Natl. Acad. Sci. USA. 88:4986-4990.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4986-4990
-
-
Sreedharan, S.P.1
Robichon, A.2
Peterson, K.E.3
Goetzl, E.J.4
-
27
-
-
0026213889
-
Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor
-
Libert, F., E. Passage, M. Parmentier, M.J. Simons, G. Vassart, and M.G. Mattei. 1991. Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor. Genomics. 11:225-227.
-
(1991)
Genomics
, vol.11
, pp. 225-227
-
-
Libert, F.1
Passage, E.2
Parmentier, M.3
Simons, M.J.4
Vassart, G.5
Mattei, M.G.6
-
28
-
-
0026595032
-
RDC1 may not be VIP receptor
-
Nagata, S., T. Ishihara, P. Robberecht, F. Libert, M. Parmentier, J. Christophe, and G. Vassart. 1992. RDC1 may not be VIP receptor. Trends Pharmacol. Sci. 13:102-103.
-
(1992)
Trends Pharmacol. Sci.
, vol.13
, pp. 102-103
-
-
Nagata, S.1
Ishihara, T.2
Robberecht, P.3
Libert, F.4
Parmentier, M.5
Christophe, J.6
Vassart, G.7
-
29
-
-
0029609367
-
Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor
-
Kapas, S., and A.J. Clark. 1995. Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor. Biochem. Biophys. Res. Commun. 217:832-838.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.217
, pp. 832-838
-
-
Kapas, S.1
Clark, A.J.2
-
30
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie, L.M., N.J. Fraser, M.J. Main, A. Wise, J. Brown, N. Thompson, R. Solari, M.G. Lee, and S.M. Foord. 1998. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 393:333-339.
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
Fraser, N.J.2
Main, M.J.3
Wise, A.4
Brown, J.5
Thompson, N.6
Solari, R.7
Lee, M.G.8
Foord, S.M.9
-
31
-
-
16844373516
-
Inverse agonism: More than reverting constitutively active receptor signaling
-
Dupre, D.J., M. Rola-Pleszczynski, and J. Stankova. 2004. Inverse agonism: more than reverting constitutively active receptor signaling. Biochem. Cell Biol. 82:676-680.
-
(2004)
Biochem. Cell Biol.
, vol.82
, pp. 676-680
-
-
Dupre, D.J.1
Rola-Pleszczynski, M.2
Stankova, J.3
-
32
-
-
21744441782
-
Structure-activity relationships of inverse agonists for G-protein-coupled receptors
-
Soudijn, W., I. van Wijngaarden, and A.P. Ijzerman. 2005. Structure-activity relationships of inverse agonists for G-protein-coupled receptors. Med. Res. Rev. 25:398-426.
-
(2005)
Med. Res. Rev.
, vol.25
, pp. 398-426
-
-
Soudijn, W.1
Van Wijngaarden, I.2
Ijzerman, A.P.3
-
33
-
-
13444261019
-
G protein-coupled receptors: A count of 1001 conformations
-
Vauquelin, G., and I. Van Liefde. 2005. G protein-coupled receptors: a count of 1001 conformations. Fundam. Clin. Pharmacol. 19:45-56.
-
(2005)
Fundam. Clin. Pharmacol.
, vol.19
, pp. 45-56
-
-
Vauquelin, G.1
Van Liefde, I.2
-
34
-
-
1242294511
-
Constitutively active Gq/11-coupled receptors enable signaling by co-expressed G(i/o)-coupled receptors
-
Bakker, R.A., P. Casarosa, H. Timmerman, M.J. Smit, and R. Leurs. 2004. Constitutively active Gq/11-coupled receptors enable signaling by co-expressed G(i/o)-coupled receptors. J. Biol. Chem. 279:5152-5161.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5152-5161
-
-
Bakker, R.A.1
Casarosa, P.2
Timmerman, H.3
Smit, M.J.4
Leurs, R.5
-
35
-
-
26444586002
-
Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28
-
Hulshof, J.W., P. Casarosa, W.M. Menge, L.M. Kuusisto, H. van der Goot, M.J. Smit, I.J. de Esch, and R. Leurs. 2005. Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28. J. Med. Chem. 48:6461-6471.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 6461-6471
-
-
Hulshof, J.W.1
Casarosa, P.2
Menge, W.M.3
Kuusisto, L.M.4
Van Der Goot, H.5
Smit, M.J.6
De Esch, I.J.7
Leurs, R.8
-
36
-
-
0033986413
-
A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses
-
Shimizu, N., Y. Soda, K. Kanbe, H.Y. Liu, R. Mukai, T. Kitamura, and H. Hoshino. 2000. A putative G protein-coupled receptor, RDC1, is a novel coreceptor for human and simian immunodeficiency viruses. J. Virol. 74:619-626.
-
(2000)
J. Virol.
, vol.74
, pp. 619-626
-
-
Shimizu, N.1
Soda, Y.2
Kanbe, K.3
Liu, H.Y.4
Mukai, R.5
Kitamura, T.6
Hoshino, H.7
-
37
-
-
27444443142
-
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
-
Balabanian, K., B. Lagane, S. Infantino, K.Y. Chow, J. Harriague, B. Moepps, F. Arenzana-Seisdedos, M. Thelen, and F. Bachelerie. 2005. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J. Biol. Chem. 280:35760-35766.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35760-35766
-
-
Balabanian, K.1
Lagane, B.2
Infantino, S.3
Chow, K.Y.4
Harriague, J.5
Moepps, B.6
Arenzana-Seisdedos, F.7
Thelen, M.8
Bachelerie, F.9
|