The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34+ cells: Role in transendothelial/stromal migration and engraftment of NOD/SCID mice

Blood

Volumn 95, Issue 11, 2000, Pages 3289-3296

  Peled, Amnon ^b   Kollet, Orit ^b   Ponomaryov, Tanya ^b   Petit, Isabelle ^b   Franitza, Suzanna ^b   Grabovsky, Valentin ^b   Slav, Michal Magid ^b   Nagler, Arnon ^b   Lider, Ofer ^b   Alon, Ronen ^b   Zipori, Dov ^b   Lapidot, Tsvee ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; CD34 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CELL ADHESION; CELL MIGRATION; ENDOTHELIUM; EXTRACELLULAR MATRIX; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STROMA; TRANSPLANTATION;

EID: 0034210221     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.11.3289.011k33_3289_3296     Document Type: Article

References (54)

1. Morrison SJ, Uchida N, Weissman IL. The biology of hematopoietic stem cells. Annu Rev Cell Dev Biol. 1995;11:35-71.
2. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood. 1993;81:2844-2853.
3. Sutherland HJ, Hogge DE, Lansdorp PM, Phillips GL, Eaves AC, Eaves CJ. Quantitation, mobilization, and clinical use of long-term culture-initiating cells in blood cell autografts. J. Hematother. 1995;4:3-10.
4. To LB, Haylock DN, Simmons PJ, Juttner CA. The biology and clinical uses of blood stem cells. Blood. 1997;7:2233-2258.
5. Lapidot T, Pelumio F, Doedens M, Murdoch B, Williams DE, Dick JE. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science. 1992; 255:1137-1141.
6. Larochelle A, Vormoor J, Hanenberg H, et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mice using retroviral gene marking and cell purification: implications for gene therapy. Nat Med. 1996;2: 1329-1337.
7. Cashman JD, Lapidot T, Wang JC, et al. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood. 1997;89:4307-4316.
8. Peled A, Petit I, Kollet O, et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science. 1999;283: 845-848.
9. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314.
10. Premack BA, Schall TJ. Chemokine receptors: gateways to inflammation and infection. Nat Med. 1996;2:1174-1178.
11. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science. 1996;272:60-66.
12. Page C, Rose M, Yacoub M, Pigott R. Antigenic heterogeneity of vascular endothelium. Am J Pathol. 1992;141:673-683.
13. Schweitzer KM, Drager AM, van der Valk P, et al. Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues. Am J Pathol. 1996;148: 165-175.
14. Frenette PS, Subbarao S, Mazo IB, von Andrian UH, Wagner DD. Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proc Natl Acad Sci USA. 1998;95:14,423-14,428.
15. Yong KL, Watts M, Shaun TN, Sullivan A, Ings S, Linen DC. Transmigration of CD34+ cells across specialized and nonspecialized endothelium requires prior activation by growth factors and is mediated by PECAM-1 (CD31). Blood. 1998,91: 1196-1205.
16. Mohle R, Moore MA, Nachman RL, Rafii S. Transendothelial migration of CD34+ and mature hematopoietic cells: an in vitro study using a human bone marrow endothelial cell line. Blood. 1997;89:72-80.
17. Campbell JJ, Hedrick J, Zlotnik A, Siani MA, Thompson DA, Butcher EC. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science. 1998;279:381-383.
18. Vermeulen M, Le Pesteur F, Gagnerault MC, Mary JY, Sainteny F, Lepault F. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood. 1998;92:894-900.
19. Quesenberry PJ, Becker PS. Stem cell homing: rolling, crawling, and nesting. Proc Natl Acad Sci USA. 1998;95:15,155-15,157.
20. Verfaillie CM. Adhesion receptors as regulators of the hematopoietic process. Blood. 1998;92:2609-2612.
21. Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, Fassler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of b1 integrins. Nature. 1996;380:171-175.
22. van der Loo JC, Xiao X, McMillin D, Hashino K, Kato I, Williams DA. VLA-5 expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin. J Clin Invest. 1998;102: 1051-1061.
23. Lobb R, Chi-Rosso G, Leone DR, et al. Expression and functional characterization of a soluble form of vascular cell adhesion molecule 1. Biochem Biophys Res Commun. 1991;178:1498-1504.
24. Jaffe EA, Nachman NL, Becker CJ, Minick CR. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J Clin Invest. 1973;52:2745-2756.
25. Teixido J, Hemler ME, Greenberger JS, Anklesaria P. Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma. J Clin Invest. 1992;90:358-367.
26. Zipori D, Duksin D, Tamir M, Argaman A, Toledo J, Malik Z. Cultured mouse marrow stromal cell lines: ii. distinct subtypes differing in morphology, collagen types, myelopoietic factors, and leukemic cell growth modulating activities. J Cell Physiol. 1985;122:81-90.
27. Carr MW, Alon R, Springer TA. The C-C chemokine MCP-1 differentially modulates the avidity of beta 1 and beta 2 integrins on T lymphocytes. Immunity. 1996;2:179-187.
28. Franitza S, Alon R, Lider O. Real-time analysis of integrin-mediated chemotactic migration of T lymphocytes within 3-D extracellular matrix-like gels. J Immunol Methods. 1999;225:9-25.
29. Graham G-J, Wright EG, Hewick R, et al. Identification and characterization of an inhibitor of haemopoietic stem cell proliferation. Nature. 1990; 344:442-444.
30. Dunlop DJ, Wright EG, Lorimore S, et al. Demonstration of stem cell inhibition and myeloprotective effects of SCI/rhMIP1 alpha in vivo. Blood. 1992;79:2221-2225.
31. Verfaillie CM, Catanzarro PM, Li WN. Macrophage inflammatory protein 1 alpha, interleukin 3 and diffusible marrow stromal factors maintain human hematopoietic stem cells for at least eight weeks in vitro. J Exp Med. 1994;179:643-649.
32. Pruijt JF, van Kooyk Y, Figdor CG, Lindley IJ, Willemze R, Fibbe WE. Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8. Blood. 1998;91:4099-4105.
33. Pruijt JF, van Kooyk Y, Figdor CG, Willemze R, Fibbe WE. Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the beta 2-integrin LFA-1. Blood. 1999;93:107-112.
34. Torensma R, Raymakers RAP, Van Kooyk Y, Figdor CG. Induction of LFA-1 on pluripotent CD34+ bone marrow cells does not affect lineage commitment. Blood. 1996;87:4120-4128.
35. Peled A, Grabovsky V, Habler L, et al. The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow. J Clin Invest. 1999;104:1199-1211.
36. Imai K, Kobayashi M, Wang J, et al. Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: a possible role in homing of haemopoietic progenitor cells to bone marrow. Br J Haematol. 1999; 106:905-911.
37. Imai K, Kobayashi M, Wang J, et al. Selective transendothelial migration of hematopoietic progenitor cells: a role in homing of progenitor cells. Blood. 1999;93:149-156.
38. Campbell JJ, Hedrick J, Zlotnik A, Siani MA, Thompson DA. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science. 1998;279:381-384.
39. Laudanna C, Campbell JJ, Butcher EC. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science. 1996;271:981-983.
40. Naiyer AJ, Jo DY, Ahn J, et al. Stromal derived factor-1-induced chemokinesis of cord blood CD34(+) cells (long-term culture-initiating cells) through endothelial cells is mediated by E-selectin. Blood. 1999;94:4011-4019.
41. Williams DA, Rios M, Stephens C, Patel VP. Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature. 1991;352: 438-441.
42. Zanjani ED, Flake AW, Almeida-Porada G, Tran N, Papayannopoulou T. Homing of human cells in the fetal sheep model: modulation by antibodies activating or inhibiting very late activation antigens-dependent function. Blood. 1999;94:2515-2522.
43. Roy V, Verfaillie CM. Expression and function of cell adhesion molecules on fetal liver, cord blood and bone marrow hematopoietic progenitors: implications for anatomical localization and developmental stage specific regulation of hematopoiesis. Exp Hematol. 1999;27:302-312.
44. Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity. 1999; 10:463-471.
45. Kawabata K, Ujikawa M, Egawa T, et al. A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution. Proc Natl Acad Sci U S A. 1999;96:5663-5667.
46. Broxmeyer HE, Hangoc G, Cooper S, Kim CH. Enhanced myelopoiesis in SDF-1-transgenic mice: SDF-1 modulates myelopoeisis by regulating progenitor cell survival and inhibitory effects of myelosuppresive chemokines [abstract]. Blood. 1999;94:650a.
47. Lataillade JJ, Clay D, Dupuy C, et al. Chemokine SDF-1 enhances circulating CD34+ cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood. 2000;95:756-768.
48. Ziegler BL, Valtieri M, Porada GA, et al. KDR receptor: a key marker defining hematopoietic stem cells. Science. 1999;285:1553-1558.
49. Peichev M, Naiyer AJ, Zhou Q, et al. Reconstitution of angiogenesis by transplantation and engraftment of ex vivo expanded human AC133 + CD34 + KDR + endothelial progenitor cells. Blood. 1998;92:504a.
50. Bendall LJ, Shen W, Makrynikola V, Bianchi A, Gottlieb DJ, Bradstock KF. Role of the chemokine, stromal cell-derived factor-1, on the migration of precursor-b acute lymphoblastic leukemia cells within the bone marrow [abstract]. Blood. 1999;94:627a.
51. Konopleva M, Monaco G, Zhao S, et al. Engraftment potential of AML progenitors into NOD/SCID mice is dependent on baseline CXCR4 expression [abstract]. Blood. 1999;94:166b.
52. Lapidot T, Ponomaryov T, Petit I, et al. The chemokine SDF-1 is produced in the bone marrow mainly by osteoblast, bone forming cells: increased production following total body irradiation, and cyclophosphamide [abstract]. Blood. 1999;94:690a.
53. Kollet O, Peled A, Lapidot T. Exclusive homing of human CD38-/lowCXCR4 + stem cells to the spleen and bone marrow of immune deficient mice within 1-16 hours [abstract]. Blood. 1999;94: 390a.
54. Spertini O, Cordey AS, Monai N, Giuffre L, Schapira M. P-selectin glycoprotein ligand t is a ligand for L-selectin on neutrophils, monocytes, and CD34 + hematopoietic progenitor cells. J Cell Biol. 1996;135:523-531.