Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection

Science Signaling

Volumn 2, Issue 100, 2009, Pages

  Zernecke, Alma ^a,b   Bidzhekov, Kiril ^a   Noels, Heidi ^a   Shagdarsuren, Erdenechimeg ^a   Gan, Lin ^a   Denecke, Bernd ^a   Hristov, Mihail ^a   Köppel, Thomas ^a   Jahantigh, Maliheh Nazari ^a   Lutgens, Esther ^a,c   Wang, Shusheng ^d   Olson, Eric N ^d   Schober, Andreas ^a   Weber, Christian ^a,c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 1; CHEMOKINE RECEPTOR CXCR4; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MICRORNA; STROMAL CELL DERIVED FACTOR 1; CXCR4 PROTEIN, HUMAN; PRIMER DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTECTION; PROTEIN FUNCTION; VASCULAR PROTECTION; ANIMAL; CYTOLOGY; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; BASE SEQUENCE; CHEMOKINE CXCL12; DISEASE MODELS, ANIMAL; DNA PRIMERS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; MICE; MICRORNAS; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77449127999     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2000610     Document Type: Article

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42. We thank M. Garbe, S. Roubrocks, and S. Wilbertz for excellent technical assistance and M. Bovi for expert help with scanning electron microscopy. This work was supported by the Deutsche Forschungsgemeinschaft (FOR809, WE1913/7-2, and 10-1, ZE827/1-1) and the Interdisciplinary Centre for Clinical Research "BIOMAT" within the Faculty of Medicine at the RWTH Aachen University (VV-B113). The authors declare no conflict of interests.