Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury

American Journal of Pathology

Volumn 176, Issue 4, 2010, Pages 1705-1715

  Chen, Jiqiu ^a   Chemaly, Elie ^a   Liang, Lifan ^a   Kho, Changwon ^a   Lee, Ahyoung ^a   Park, Jaeho ^a   Altman, Perry ^a   Schecter, Alison D ^b   Hajjar, Roger J ^a   Tarzami, Sima T ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1; TRIPHENYLTETRAZOLIUM; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROL GROUP; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ECHOCARDIOGRAPHY; GENE OVEREXPRESSION; GENE TRANSFER; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HISTOPATHOLOGY; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; STAINING;

EID: 77950574556     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090451     Document Type: Article

References (49)

1. Tissier R, Berdeaux A, Ghaleh B, Couvreur N, Krieg T, Cohen MV, Downey JM: Making the heart resistant to infarction: how can we further decrease infarct size? Front Biosci 2008, 13:284-301
2. Yellon DM, Baxter GF: Protecting the ischaemic and reperfused myocardium in acute myocardial infarction: distant dream or near reality? Heart 2000, 83:381-387
3. Carden DL, Granger DN: Pathophysiology of ischaemia-reperfusion injury. J Pathol 2000, 190:255-266
4. Vermeiren GL, Claeys MJ, Van Bockstaele D, Grobben B, Slegers H, Bossaert L, Jorens PG: Reperfusion injury after focal myocardial ischaemia: polymorphonuclear leukocyte activation and its clinical implications. Resuscitation 2000, 45:35-61 (Pubitemid 30320958)
5. Gao L, Yin H, S. Smith RJ, Chao L, Chao J: Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarction. Lab Invest 2008, 88:1157-1166
6. Abbott JD, Huang Y, Liu D, Hickey R, Krause DS, Giordano FJ: Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004, 110:3300-3305 (Pubitemid 39557491)
7. Luster AD: Chemokines-chemotactic cytokines that mediate inflammation. N Engl J Med 1998, 338:436-445
8. Pease JE, Williams TJ: The attraction of chemokines as a target for specific anti-inflammatory therapy. Br J Pharmacol 2006, 147 Suppl 1:S212-S21
9. Damas JK, Eiken HG, Oie E, Bjerkeli V, Yndestad A, Ueland T, Tonnessen T, Geiran OR, Aass H, Simonsen S, Christensen G, Froland SS, Attramadal H, Gullestad L, Aukrust P: Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure. Cardiovasc Res 2000, 47:778-787
10. Sasayama S, Okada M, Matsumori A: Chemokines and cardiovascular diseases. Cardiovasc Res 2000, 45:267-269
11. Ma J, Ge J, Zhang S, Sun A, Shen J, Chen L, Wang K, Zou Y: Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction. Basic Res Cardiol 2005, 100:217-223 (Pubitemid 41348812)
12. Segret A, Rucker-Martin C, Pavoine C, Flavigny J, Deroubaix E, Chatel MA, Lombet A, Renaud JF: Structural localization and expression of CXCL12 and CXCR4 in rat heart and isolated cardiac myocytes. J Histochem Cytochem 2007, 55:141-150 (Pubitemid 46147691)
13. Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, Bronson RT, Springer TA: Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci USA 1998, 95:9448-9453 (Pubitemid 28506251)
14. Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR: Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 1998, 393:595-599 (Pubitemid 28319251)
15. Pyo RT, Sui J, Dhume A, Palomeque J, Blaxall BC, Diaz G, Tunstead J, Logothetis DE, Hajjar RJ, Schecter AD: CXCR4 modulates contractility in adult cardiac myocytes. J Mol Cell Cardiol 2006, 41:834-844 (Pubitemid 44635574)
16. Hajjar RJ, Schmidt U, Matsui T, Guerrero JL, Lee KH, Gwathmey JK, Dec GW, Semigran MJ, Rosenzweig A: Modulation of ventricular function through gene transfer in vivo. Proc Natl Acad Sci USA 1998, 95:5251-5256 (Pubitemid 28208584)
17. Tarzami ST, Miao W, Mani K, Lopez L, Factor SM, Berman JW, Kitsis RN: Opposing effects mediated by the chemokine receptor CXCR2 on myocardial ischemia-reperfusion injury: recruitment of potentially damaging neutrophils and direct myocardial protection. Circulation 2003, 108:2387-2392 (Pubitemid 37413547)
18. del Monte F, Lebeche D, Guerrero JL, Tsuji T, Doye AA, Gwathmey JK, Hajjar RJ: Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proc Natl Acad Sci USA 2004, 101:5622-5627 (Pubitemid 38481206)
19. Zhu BQ, Simonis U, Cecchini G, Zhou HZ, Li L, Teerlink JR, Karliner JS: Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther 2006, 11:119-128 (Pubitemid 44449101)
20. Chen J, Kuhlencordt P, Urano F, Ichinose H, Astern J, Huang PL: Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice. Arterioscler Thromb Vasc Biol 2003, 23:97-103 (Pubitemid 36091632)
21. Tarzami ST, Cheng R, Miao W, Kitsis RN, Berman JW: Chemokine expression in myocardial ischemia: mIP-2 dependent MCP-1 expression protects cardiomyocytes from cell death. J Mol Cell Cardiol 2002, 34:209-221 (Pubitemid 35222830)
22. Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R: In vivo imaging of proteolytic activity in atherosclerosis. Circulation 2002, 105:2766-2771
23. Zhan RZ, Wu C, Fujihara H, Taga K, Qi S, Naito M, Shimoji K: Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model. J Cereb Blood Flow Metab 2001, 21:529-540 (Pubitemid 32422873)
24. Yndestad A, Damas JK, Oie E, Ueland T, Gullestad L, Aukrust P: Role of inflammation in the progression of heart failure. Curr Cardiol Rep 2007, 9:236-241 (Pubitemid 46784419)
25. Mehra VC, Ramgolam VS, Bender JR: Cytokines and cardiovascular disease. J Leukoc Biol 2005, 78:805-818
26. Blum A, Miller H: Pathophysiological role of cytokines in congestive heart failure. Annu Rev Med 2001, 52:15-27 (Pubitemid 32195312)
27. Cain BS, Meldrum DR, Dinarello CA, Meng X, Banerjee A, Harken AH: Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion. J Surg Res 1998, 76:117-123 (Pubitemid 28360008)
28. Krown KA, Page MT, Nguyen C, Zechner D, Gutierrez V, Comstock KL, Glembotski CC, Quintana PJ, Sabbadini RA: Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest 1996, 98:2854-2865 (Pubitemid 26427415)
29. Nian M, Lee P, Khaper N, Liu P: Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res 2004, 94:1543-1553 (Pubitemid 38856961)
30. Issekutz TB, Stoltz JM: Stimulation of lymphocyte migration by endotoxin, tumor necrosis factor, and interferon. Cell Immunol 1989, 120:165-173 (Pubitemid 19113720)
31. Issekutz TB: Effects of six different cytokines on lymphocyte adherence to microvascular endothelium and in vivo lymphocyte migration in the rat. J Immunol 1990, 144:2140-2146
32. Youker KA, Hawkins HK, Kukielka GL, Perrard JL, Michael LH, Ballantyne CM, Smith CW, Entman ML: Molecular evidence for a border zone vulnerable to inflammatory reperfusion injury. Trans Assoc Am Physicians 1993, 106:145-154
33. Youker KA, Hawkins HK, Kukielka GL, Perrard JL, Michael LH, Ballantyne CM, Smith CW, Entman ML: Molecular evidence for induction of intracellular adhesion molecule-1 in the viable border zone associated with ischemia-reperfusion injury of the dog heart. Circulation 1994, 89:2736-2746
34. Kukielka GL, Youker KA, Michael LH, Kumar AG, Ballantyne CM, Smith CW, Entman ML: Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium. Mol Cell Biochem 1995, 147:5-12
35. Frangogiannis NG, Smith CW, Entman ML: The inflammatory response in myocardial infarction. Cardiovasc Res 2002, 53:31-47
36. Misao Y, Arai M, Ohno T, Ushikoshi H, Onogi H, Kobayashi H, Takemura G, Minatoguchi S, Fujiwara T, Fujiwara H: Modification of post-myocardial infarction granulocyte-colony stimulating factor therapy with myelo-suppressives. Circ J 2007, 71:580-590 (Pubitemid 46513469)
37. Misao Y, Takemura G, Arai M, Ohno T, Onogi H, Takahashi T, Minatoguchi S, Fujiwara T, Fujiwara H: Importance of recruitment of bone marrow-derived CXCR4+ cells in post-infarct cardiac repair mediated by G-CSF. Cardiovasc Res 2006, 71:455-465 (Pubitemid 44107862)
38. Willerson JT, Buja LM: Protection of the myocardium during myocardial infarction: pharmacologic protection during thrombolytic therapy. Am J Cardiol 1990, 65:35I- 41I
39. Schmidt U, del Monte F, Miyamoto MI, Matsui T, Gwathmey JK, Rosenzweig A, Hajjar RJ: Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circulation 2000, 101:790-796
40. Hu X, Dai S, Wu WJ, Tan W, Zhu X, Mu J, Guo Y, Bolli R, Rokosh G: Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation 2007, 116:654-663 (Pubitemid 47356350)
41. Jordan JE, Zhao ZQ, Vinten-Johansen J: The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res 1999, 43:860-878 (Pubitemid 29413185)
42. McQuibban GA, Butler GS, Gong JH, Bendall L, Power C, Clark-Lewis I, Overall CM: Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1. J Biol Chem 2001, 276:43503-43508 (Pubitemid 37383907)
43. Zwacka RM, Zhang Y, Halldorson J, Schlossberg H, Dudus L, Engelhardt JF: CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver. J Clin Invest 1997, 100:279-289 (Pubitemid 27349074)
44. Schilling M, Strecker JK, Schabitz WR, Ringelstein EB, Kiefer R: Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice. Neuroscience 2009, 161:806-812
45. Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J: Clinical implications of apoptosis in ischemic myocardium. Curr Probl Cardiol 2006, 31:181-264 (Pubitemid 43287989)
46. Colamussi ML, Secchiero P, Zella D, Curreli S, Mirandola P, Capitani S, Zauli G: Stromal derived factor-1alpha induces apoptosis in activated primary CD4+ T cells. Aids 2000, 14:748-750 (Pubitemid 30229357)
47. Wu Y, Tu X, Lin G, Xia H, Huang H, Wan J, Cheng Z, Liu M, Chen G, Zhang H, Fu J, Liu Q, Liu DX: Emodin-mediated protection from acute myocardial infarction via inhibition of inflammation and apoptosis in local ischemic myocardium. Life Sci 2007, 81:1332-1338 (Pubitemid 47599527)
48. Han Y, He T, Huang DR, Pardo CA, Ransohoff RM: TNF-alpha mediates SDF-1 alpha-induced NF-kappa B activation and cytotoxic effects in primary astrocytes. J Clin Invest 2001, 108:425-435 (Pubitemid 32730789)
49. Zhang Q, Guo R, Schwarz EM, Boyce BF, Xing L: TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood. Arthritis Res Ther 2008, 10:R37 (Pubitemid 351587124)