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Volumn 112, Issue 13, 2015, Pages E1659-E1668

Heteromerization of chemokine (C-X-C motif) receptor 4 with α1A/B -adrenergic receptors controls adrenergic α1 receptor function

Author keywords

AMD3100; Blood pressure; CXCL12; Phenylephrine; Ubiquitin

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CALCIUM ION; CHEMOKINE RECEPTOR CXCR4; DOPAMINE RECEPTOR; G PROTEIN COUPLED RECEPTOR; MYOSIN LIGHT CHAIN 2; PHENYLEPHRINE; PLERIXAFOR; UBIQUITIN; ADRA1A PROTEIN, HUMAN; ADRA1A PROTEIN, RAT; ADRA1B PROTEIN, HUMAN; ADRA1B PROTEIN, RAT; CXCL12 PROTEIN, HUMAN; CXCL12 PROTEIN, RAT; CXCR4 PROTEIN, HUMAN; CXCR4 PROTEIN, RAT; HETEROCYCLIC COMPOUND; STROMAL CELL DERIVED FACTOR 1;

EID: 84961289810     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417564112     Document Type: Article
Times cited : (57)

References (78)
  • 1
    • 54549087794 scopus 로고    scopus 로고
    • Anatomical profiling of G protein-coupled receptor expression
    • Regard JB, Sato IT, Coughlin SR (2008) Anatomical profiling of G protein-coupled receptor expression. Cell 135(3):561-571.
    • (2008) Cell , vol.135 , Issue.3 , pp. 561-571
    • Regard, J.B.1    Sato, I.T.2    Coughlin, S.R.3
  • 2
    • 84887512970 scopus 로고    scopus 로고
    • International Union of Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors
    • Bachelerie F, et al. (2014) International Union of Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev 66(1):1-79.
    • (2014) Pharmacol Rev , vol.66 , Issue.1 , pp. 1-79
    • Bachelerie, F.1
  • 3
    • 77953090345 scopus 로고    scopus 로고
    • CXCL12 (SDF-1)/CXCR4 pathway in cancer
    • Teicher BA, Fricker SP (2010) CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res 16(11):2927-2931.
    • (2010) Clin Cancer Res , vol.16 , Issue.11 , pp. 2927-2931
    • Teicher, B.A.1    Fricker, S.P.2
  • 4
    • 0032104460 scopus 로고    scopus 로고
    • A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: Their functions in development, hematopoiesis and HIV infection
    • Nagasawa T, Tachibana K, Kishimoto T (1998) A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: Their functions in development, hematopoiesis and HIV infection. Semin Immunol 10(3):179-185.
    • (1998) Semin Immunol , vol.10 , Issue.3 , pp. 179-185
    • Nagasawa, T.1    Tachibana, K.2    Kishimoto, T.3
  • 5
    • 84856389868 scopus 로고    scopus 로고
    • CXCR4 antagonism attenuates the cardiorenal consequences of mineralocorticoid excess
    • Chu PY, et al. (2011) CXCR4 antagonism attenuates the cardiorenal consequences of mineralocorticoid excess. Circ Heart Fail 4(5):651-658.
    • (2011) Circ Heart Fail , vol.4 , Issue.5 , pp. 651-658
    • Chu, P.Y.1
  • 6
    • 79551596160 scopus 로고    scopus 로고
    • Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats
    • Yu L, Hales CA (2011) Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats. Respir Res 12:21.
    • (2011) Respir Res , vol.12 , pp. 21
    • Yu, L.1    Hales, C.A.2
  • 7
    • 84866751261 scopus 로고    scopus 로고
    • Initial assessment of the role of CXC chemokine receptor 4 after polytrauma
    • Bach HH, IV, et al. (2012) Initial assessment of the role of CXC chemokine receptor 4 after polytrauma. Mol Med 18:1056-1066.
    • (2012) Mol Med , vol.18 , pp. 1056-1066
    • Bach, H.H.1
  • 8
    • 84921947993 scopus 로고    scopus 로고
    • Chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 regulate vascular α?-adrenergic receptor function
    • Bach HH, IV, et al. (2014) Chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 regulate vascular α?-adrenergic receptor function. Mol Med 20:435-447.
    • (2014) Mol Med , vol.20 , pp. 435-447
    • Bach, H.H.1
  • 9
    • 26244434858 scopus 로고    scopus 로고
    • Ubiquitin reduces fluid shifts after traumatic brain injury
    • Earle SA, Proctor KG, Patel MB, Majetschak M (2005) Ubiquitin reduces fluid shifts after traumatic brain injury. Surgery 138(3):431-438.
    • (2005) Surgery , vol.138 , Issue.3 , pp. 431-438
    • Earle, S.A.1    Proctor, K.G.2    Patel, M.B.3    Majetschak, M.4
  • 10
    • 2342503177 scopus 로고    scopus 로고
    • Effects of exogenous ubiquitin in lethal endotoxemia
    • Majetschak M, et al. (2004) Effects of exogenous ubiquitin in lethal endotoxemia. Surgery 135(5):536-543.
    • (2004) Surgery , vol.135 , Issue.5 , pp. 536-543
    • Majetschak, M.1
  • 11
    • 2942739032 scopus 로고    scopus 로고
    • Therapeutic potential of exogenous ubiquitin during resuscitation from severe trauma
    • discussion 999-1000
    • Majetschak M, Cohn SM, Obertacke U, Proctor KG (2004) Therapeutic potential of exogenous ubiquitin during resuscitation from severe trauma. J Trauma 56(5): 991-999; discussion 999-1000.
    • (2004) J Trauma , vol.56 , Issue.5 , pp. 991-999
    • Majetschak, M.1    Cohn, S.M.2    Obertacke, U.3    Proctor, K.G.4
  • 12
    • 84864290127 scopus 로고    scopus 로고
    • Effects of exogenous ubiquitin in a polytrauma model with blunt chest trauma
    • Baker TA, et al. (2012) Effects of exogenous ubiquitin in a polytrauma model with blunt chest trauma. Crit Care Med 40(8):2376-2384.
    • (2012) Crit Care Med , vol.40 , Issue.8 , pp. 2376-2384
    • Baker, T.A.1
  • 13
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • Moore CA, Milano SK, Benovic JL (2007) Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol 69:451-482.
    • (2007) Annu Rev Physiol , vol.69 , pp. 451-482
    • Moore, C.A.1    Milano, S.K.2    Benovic, J.L.3
  • 15
    • 0038487327 scopus 로고    scopus 로고
    • The ins and outs of G protein-coupled receptor trafficking
    • Marchese A, Chen C, Kim YM, Benovic JL (2003) The ins and outs of G protein-coupled receptor trafficking. Trends Biochem Sci 28(7):369-376.
    • (2003) Trends Biochem Sci , vol.28 , Issue.7 , pp. 369-376
    • Marchese, A.1    Chen, C.2    Kim, Y.M.3    Benovic, J.L.4
  • 16
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmembrane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ (2002) Seven-transmembrane-spanning receptors and heart function. Nature 415(6868):206-212.
    • (2002) Nature , vol.415 , Issue.6868 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 17
    • 0029976109 scopus 로고    scopus 로고
    • Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor
    • Diviani D, et al. (1996) Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor. J Biol Chem 271(9):5049-5058.
    • (1996) J Biol Chem , vol.271 , Issue.9 , pp. 5049-5058
    • Diviani, D.1
  • 18
    • 0025040526 scopus 로고
    • Mechanisms involved in adrenergic receptor desensitization
    • Collins S, et al. (1990) Mechanisms involved in adrenergic receptor desensitization. Biochem Soc Trans 18(4):541-544.
    • (1990) Biochem Soc Trans , vol.18 , Issue.4 , pp. 541-544
    • Collins, S.1
  • 19
    • 33646386694 scopus 로고    scopus 로고
    • Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex
    • McGraw DW, et al. (2006) Airway smooth muscle prostaglandin-EP1 receptors directly modulate beta2-adrenergic receptors within a unique heterodimeric complex. J Clin Invest 116(5):1400-1409.
    • (2006) J Clin Invest , vol.116 , Issue.5 , pp. 1400-1409
    • McGraw, D.W.1
  • 20
    • 0036399259 scopus 로고    scopus 로고
    • Receptor crosstalk. Implications for cardiovascular function, disease and therapy
    • Dzimiri N (2002) Receptor crosstalk. Implications for cardiovascular function, disease and therapy. Eur J Biochem 269(19):4713-4730.
    • (2002) Eur J Biochem , vol.269 , Issue.19 , pp. 4713-4730
    • Dzimiri, N.1
  • 21
    • 77649096828 scopus 로고    scopus 로고
    • Receptor heteromerization and drug discovery
    • Rozenfeld R, Devi LA (2010) Receptor heteromerization and drug discovery. Trends Pharmacol Sci 31(3):124-130.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.3 , pp. 124-130
    • Rozenfeld, R.1    Devi, L.A.2
  • 22
    • 84893642127 scopus 로고    scopus 로고
    • G protein-coupled receptor oligomerization revisited: Functional and pharmacological perspectives
    • Ferré S, et al. (2014) G protein-coupled receptor oligomerization revisited: Functional and pharmacological perspectives. Pharmacol Rev 66(2):413-434.
    • (2014) Pharmacol Rev , vol.66 , Issue.2 , pp. 413-434
    • Ferré, S.1
  • 24
    • 0842285404 scopus 로고    scopus 로고
    • Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor
    • Rodríguez-Frade JM, et al. (2004) Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor. EMBO J 23(1):66-76.
    • (2004) EMBO J , vol.23 , Issue.1 , pp. 66-76
    • Rodríguez-Frade, J.M.1
  • 25
    • 84875187354 scopus 로고    scopus 로고
    • Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes
    • Watts AO, et al. (2013) Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes. Br J Pharmacol 168(7):1662-1674.
    • (2013) Br J Pharmacol , vol.168 , Issue.7 , pp. 1662-1674
    • Watts, A.O.1
  • 26
    • 48249131606 scopus 로고    scopus 로고
    • CXCR4-CCR5: A couple modulating T cell functions
    • Contento RL, et al. (2008) CXCR4-CCR5: A couple modulating T cell functions. Proc Natl Acad Sci USA 105(29):10101-10106.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.29 , pp. 10101-10106
    • Contento, R.L.1
  • 27
    • 67650349084 scopus 로고    scopus 로고
    • CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
    • Levoye A, Balabanian K, Baleux F, Bachelerie F, Lagane B (2009) CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling. Blood 113(24):6085-6093.
    • (2009) Blood , vol.113 , Issue.24 , pp. 6085-6093
    • Levoye, A.1    Balabanian, K.2    Baleux, F.3    Bachelerie, F.4    Lagane, B.5
  • 28
    • 0141890300 scopus 로고    scopus 로고
    • Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization
    • Stanasila L, Perez JB, Vogel H, Cotecchia S (2003) Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization. J Biol Chem 278(41):40239-40251.
    • (2003) J Biol Chem , vol.278 , Issue.41 , pp. 40239-40251
    • Stanasila, L.1    Perez, J.B.2    Vogel, H.3    Cotecchia, S.4
  • 29
    • 33645902491 scopus 로고    scopus 로고
    • Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: The heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
    • Small KM, et al. (2006) Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: The heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment. Biochemistry 45(15):4760-4767.
    • (2006) Biochemistry , vol.45 , Issue.15 , pp. 4760-4767
    • Small, K.M.1
  • 30
    • 0141841603 scopus 로고    scopus 로고
    • Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: A functional role for re-ceptor-receptor interaction in vivo
    • Barki-Harrington L, Luttrell LM, Rockman HA (2003) Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: A functional role for re-ceptor-receptor interaction in vivo. Circulation 108(13):1611-1618.
    • (2003) Circulation , vol.108 , Issue.13 , pp. 1611-1618
    • Barki-Harrington, L.1    Luttrell, L.M.2    Rockman, H.A.3
  • 31
    • 0037144542 scopus 로고    scopus 로고
    • Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy
    • Lavoie C, et al. (2002) Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy. J Biol Chem 277(38):35402-35410.
    • (2002) J Biol Chem , vol.277 , Issue.38 , pp. 35402-35410
    • Lavoie, C.1
  • 32
    • 0037518126 scopus 로고    scopus 로고
    • Heterodimerization of alpha 2A- and beta 1-adrenergic receptors
    • Xu J, et al. (2003) Heterodimerization of alpha 2A- and beta 1-adrenergic receptors. J Biol Chem 278(12):10770-10777.
    • (2003) J Biol Chem , vol.278 , Issue.12 , pp. 10770-10777
    • Xu, J.1
  • 33
    • 33747585593 scopus 로고    scopus 로고
    • Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors
    • Prinster SC, Holmqvist TG, Hall RA (2006) Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors. J Pharmacol Exp Ther 318(3):974-981.
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.3 , pp. 974-981
    • Prinster, S.C.1    Holmqvist, T.G.2    Hall, R.A.3
  • 34
    • 84873252073 scopus 로고    scopus 로고
    • Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling
    • Chandrasekera PC, Wan TC, Gizewski ET, Auchampach JA, Lasley RD (2013) Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling. Cell Signal 25(4): 736-742.
    • (2013) Cell Signal , vol.25 , Issue.4 , pp. 736-742
    • Chandrasekera, P.C.1    Wan, T.C.2    Gizewski, E.T.3    Auchampach, J.A.4    Lasley, R.D.5
  • 35
    • 84859768529 scopus 로고    scopus 로고
    • Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer
    • Mustafa S, et al. (2012) Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer. J Biol Chem 287(16):12952-12965.
    • (2012) J Biol Chem , vol.287 , Issue.16 , pp. 12952-12965
    • Mustafa, S.1
  • 36
    • 78650172422 scopus 로고    scopus 로고
    • β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4
    • LaRocca TJ, et al. (2010) β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. J Cardiovasc Pharmacol 56(5):548-559.
    • (2010) J Cardiovasc Pharmacol , vol.56 , Issue.5 , pp. 548-559
    • LaRocca, T.J.1
  • 37
    • 84961290596 scopus 로고    scopus 로고
    • Control of lymphocyte egress from lymph nodes through β2-adrenergic receptors
    • Nakai A, Hayano Y, Furuta F, Noda M, Suzuki K (2014) Control of lymphocyte egress from lymph nodes through β2-adrenergic receptors. J Exp Med 211(13):2583-2598.
    • (2014) J Exp Med , vol.211 , Issue.13 , pp. 2583-2598
    • Nakai, A.1    Hayano, Y.2    Furuta, F.3    Noda, M.4    Suzuki, K.5
  • 38
    • 33751252292 scopus 로고    scopus 로고
    • Direct observation of individual endogenous protein complexes in situ by proximity ligation
    • Söderberg O, et al. (2006) Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods 3(12):995-1000.
    • (2006) Nat Methods , vol.3 , Issue.12 , pp. 995-1000
    • Söderberg, O.1
  • 39
    • 84893141143 scopus 로고    scopus 로고
    • Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels
    • Brueggemann LI, et al. (2014) Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels. J Biol Chem 289(4):2099-2111.
    • (2014) J Biol Chem , vol.289 , Issue.4 , pp. 2099-2111
    • Brueggemann, L.I.1
  • 40
    • 84892483373 scopus 로고    scopus 로고
    • CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin
    • Tripathi A, Davis JD, Staren DM, Volkman BF, Majetschak M (2014) CXC chemokine receptor 4 signaling upon co-activation with stromal cell-derived factor-1α and ubiquitin. Cytokine 65(2):121-125.
    • (2014) Cytokine , vol.65 , Issue.2 , pp. 121-125
    • Tripathi, A.1    Davis, J.D.2    Staren, D.M.3    Volkman, B.F.4    Majetschak, M.5
  • 41
    • 0029666267 scopus 로고    scopus 로고
    • A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation
    • Hebert TE, et al. (1996) A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J Biol Chem 271(27):16384-16392.
    • (1996) J Biol Chem , vol.271 , Issue.27 , pp. 16384-16392
    • Hebert, T.E.1
  • 42
    • 79959951981 scopus 로고    scopus 로고
    • Structural plasticity of a transmembrane peptide allows selfassembly into biologically active nanoparticles
    • Tarasov SG, et al. (2011) Structural plasticity of a transmembrane peptide allows selfassembly into biologically active nanoparticles. Proc Natl Acad Sci USA 108(24): 9798-9803.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.24 , pp. 9798-9803
    • Tarasov, S.G.1
  • 43
    • 0032589062 scopus 로고    scopus 로고
    • Analysis of alpha1-adrenoceptor subtypes in rabbit aorta and arteries: Regional difference and co-existence
    • Satoh M, Enomoto K, Takayanagi I, Koike K (1999) Analysis of alpha1-adrenoceptor subtypes in rabbit aorta and arteries: Regional difference and co-existence. Eur J Pharmacol 374(2):229-240.
    • (1999) Eur J Pharmacol , vol.374 , Issue.2 , pp. 229-240
    • Satoh, M.1    Enomoto, K.2    Takayanagi, I.3    Koike, K.4
  • 44
    • 73849149844 scopus 로고    scopus 로고
    • Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
    • Bokoch MP, et al. (2010) Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature 463(7277):108-112.
    • (2010) Nature , vol.463 , Issue.7277 , pp. 108-112
    • Bokoch, M.P.1
  • 45
    • 85027927015 scopus 로고    scopus 로고
    • Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
    • Wu B, et al. (2010) Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 330(6007):1066-1071.
    • (2010) Science , vol.330 , Issue.6007 , pp. 1066-1071
    • Wu, B.1
  • 46
    • 84861096654 scopus 로고    scopus 로고
    • Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
    • Manglik A, et al. (2012) Crystal structure of the μ-opioid receptor bound to a morphinan antagonist. Nature 485(7398):321-326.
    • (2012) Nature , vol.485 , Issue.7398 , pp. 321-326
    • Manglik, A.1
  • 47
    • 84862777742 scopus 로고    scopus 로고
    • Structure of the human ê-opioid receptor in complex with JDTic
    • Wu H, et al. (2012) Structure of the human ê-opioid receptor in complex with JDTic. Nature 485(7398):327-332.
    • (2012) Nature , vol.485 , Issue.7398 , pp. 327-332
    • Wu, H.1
  • 48
    • 33750836895 scopus 로고    scopus 로고
    • Crystal structure of a photoactivated deprotonated intermediate of rhodopsin
    • Salom D, et al. (2006) Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci USA 103(44):16123-16128.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.44 , pp. 16123-16128
    • Salom, D.1
  • 49
    • 84876197291 scopus 로고    scopus 로고
    • Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state
    • Huang J, Chen S, Zhang JJ,Huang XY(2013) Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat Struct Mol Biol 20(4):419-425.
    • (2013) Nat Struct Mol Biol , vol.20 , Issue.4 , pp. 419-425
    • Huang, J.1    Chen, S.2    Zhang, J.J.3    Huang, X.Y.4
  • 50
    • 77952014394 scopus 로고    scopus 로고
    • CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin
    • Saini V, Marchese A, Majetschak M (2010) CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. J Biol Chem 285(20):15566-15576.
    • (2010) J Biol Chem , vol.285 , Issue.20 , pp. 15566-15576
    • Saini, V.1    Marchese, A.2    Majetschak, M.3
  • 51
    • 80052987287 scopus 로고    scopus 로고
    • The CXC chemokine receptor 4 ligands ubiquitin and stromal cellderived factor-1α function through distinct receptor interactions
    • Saini V, et al. (2011) The CXC chemokine receptor 4 ligands ubiquitin and stromal cellderived factor-1α function through distinct receptor interactions. J Biol Chem 286(38): 33466-33477.
    • (2011) J Biol Chem , vol.286 , Issue.38 , pp. 33466-33477
    • Saini, V.1
  • 52
    • 77953301324 scopus 로고    scopus 로고
    • N-linked glycosylation of protease-activated receptor-1 second extracellular loop: A critical determinant for ligand-induced receptor activation and internalization
    • Soto AG, Trejo J (2010) N-linked glycosylation of protease-activated receptor-1 second extracellular loop: A critical determinant for ligand-induced receptor activation and internalization. J Biol Chem 285(24):18781-18793.
    • (2010) J Biol Chem , vol.285 , Issue.24 , pp. 18781-18793
    • Soto, A.G.1    Trejo, J.2
  • 53
    • 0036913795 scopus 로고    scopus 로고
    • CXCR4 heterogeneity in primary cells: Possible role of ubiquitination
    • Lapham CK, et al. (2002) CXCR4 heterogeneity in primary cells: Possible role of ubiquitination. J Leukoc Biol 72(6):1206-1214.
    • (2002) J Leukoc Biol , vol.72 , Issue.6 , pp. 1206-1214
    • Lapham, C.K.1
  • 54
    • 74549184056 scopus 로고    scopus 로고
    • CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation
    • Carlisle AJ, Lyttle CA, Carlisle RY, Maris JM (2009) CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation. Mol Cancer 8:126.
    • (2009) Mol Cancer , vol.8 , pp. 126
    • Carlisle, A.J.1    Lyttle, C.A.2    Carlisle, R.Y.3    Maris, J.M.4
  • 55
    • 84880029997 scopus 로고    scopus 로고
    • Modulation of in-membrane receptor clustering upon binding of multivalent ligands
    • Grochmal A, Ferrero E, Milanesi L, Tomas S (2013) Modulation of in-membrane receptor clustering upon binding of multivalent ligands. J Am Chem Soc 135(27): 10172-10177.
    • (2013) J am Chem Soc , vol.135 , Issue.27 , pp. 10172-10177
    • Grochmal, A.1    Ferrero, E.2    Milanesi, L.3    Tomas, S.4
  • 56
    • 84859129537 scopus 로고    scopus 로고
    • In vitro study on the effects of some selected agonists and antagonists of alpha(1)-adrenergic receptors on the contractility of the aneurysmallychanged aortic smooth muscle in humans
    • Gnus J, et al. (2012) In vitro study on the effects of some selected agonists and antagonists of alpha(1)-adrenergic receptors on the contractility of the aneurysmallychanged aortic smooth muscle in humans. J Physiol Pharmacol 63(1):29-34.
    • (2012) J Physiol Pharmacol , vol.63 , Issue.1 , pp. 29-34
    • Gnus, J.1
  • 57
    • 84863010954 scopus 로고    scopus 로고
    • Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism
    • Kern A, Albarran-Zeckler R, Walsh HE, Smith RG (2012) Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron 73(2):317-332.
    • (2012) Neuron , vol.73 , Issue.2 , pp. 317-332
    • Kern, A.1    Albarran-Zeckler, R.2    Walsh, H.E.3    Smith, R.G.4
  • 58
    • 84883475479 scopus 로고    scopus 로고
    • The ubiquitin-CXCR4 axis plays an important role in acute lung infection-enhanced lung tumor metastasis
    • Yan L, Cai Q, Xu Y (2013) The ubiquitin-CXCR4 axis plays an important role in acute lung infection-enhanced lung tumor metastasis. Clin Cancer Res 19(17):4706-4716.
    • (2013) Clin Cancer Res , vol.19 , Issue.17 , pp. 4706-4716
    • Yan, L.1    Cai, Q.2    Xu, Y.3
  • 59
    • 84894498335 scopus 로고    scopus 로고
    • Targeted delivery of ubiquitin-conjugated BH3 peptide-based Mcl-1 inhibitors into cancer cells
    • Muppidi A, et al. (2014) Targeted delivery of ubiquitin-conjugated BH3 peptide-based Mcl-1 inhibitors into cancer cells. Bioconjug Chem 25(2):424-432.
    • (2014) Bioconjug Chem , vol.25 , Issue.2 , pp. 424-432
    • Muppidi, A.1
  • 60
    • 84901030382 scopus 로고    scopus 로고
    • Extracellular ubiquitin increases expression of angiogenic molecules and stimulates angiogenesis in cardiac microvascular endothelial cells
    • Steagall RJ, et al. (2014) Extracellular ubiquitin increases expression of angiogenic molecules and stimulates angiogenesis in cardiac microvascular endothelial cells. Microcirculation 21(4):324-332.
    • (2014) Microcirculation , vol.21 , Issue.4 , pp. 324-332
    • Steagall, R.J.1
  • 61
    • 84946215643 scopus 로고    scopus 로고
    • Serum ubiquitin via CXC chemokine receptor 4triggered cyclooxygenase-1 ubiquitination possibly involved in the pathogenesis of aspirin resistance
    • Tan C, Lu X, Chen W, Chen S (2014) Serum ubiquitin via CXC chemokine receptor 4triggered cyclooxygenase-1 ubiquitination possibly involved in the pathogenesis of aspirin resistance. Clin Hemorheol Microcirc, 10.3233/CH-141900.
    • (2014) Clin Hemorheol Microcirc
    • Tan, C.1    Lu, X.2    Chen, W.3    Chen, S.4
  • 62
    • 84922020837 scopus 로고    scopus 로고
    • Extracellular ubiquitin enhances the suppressive effects of regulatory T cells on effector T cell responses
    • Cao Y, Li C, Zhang Q, Wang Y, Xia R (2014) Extracellular ubiquitin enhances the suppressive effects of regulatory T cells on effector T cell responses. Clin Lab 60(12): 1983-1991.
    • (2014) Clin Lab , vol.60 , Issue.12 , pp. 1983-1991
    • Cao, Y.1    Li, C.2    Zhang, Q.3    Wang, Y.4    Xia, R.5
  • 63
    • 27444443142 scopus 로고    scopus 로고
    • The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
    • Balabanian K, et al. (2005) The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 280(42):35760-35766.
    • (2005) J Biol Chem , vol.280 , Issue.42 , pp. 35760-35766
    • Balabanian, K.1
  • 64
    • 79958743310 scopus 로고    scopus 로고
    • Differential estrogen-regulation of CXCL12 chemokine receptors, CXCR4 and CXCR7, contributes to the growth effect of estrogens in breast cancer cells
    • Boudot A, et al. (2011) Differential estrogen-regulation of CXCL12 chemokine receptors, CXCR4 and CXCR7, contributes to the growth effect of estrogens in breast cancer cells. PLoS ONE 6(6):e20898.
    • (2011) PLoS ONE , vol.6 , Issue.6 , pp. e20898
    • Boudot, A.1
  • 65
    • 0037390719 scopus 로고    scopus 로고
    • The N- and C-terminal fragments of ubiquitin are important for the antimicrobial activities
    • Kieffer AE, et al. (2003) The N- and C-terminal fragments of ubiquitin are important for the antimicrobial activities. FASEB J 17(6):776-778.
    • (2003) FASEB J , vol.17 , Issue.6 , pp. 776-778
    • Kieffer, A.E.1
  • 66
    • 84921875408 scopus 로고    scopus 로고
    • Angiotensin II type I and prostaglandin F2alpha receptors cooperatively modulate signaling in vascular smooth muscle cells
    • Goupil E, et al. (2015) Angiotensin II type I and prostaglandin F2alpha receptors cooperatively modulate signaling in vascular smooth muscle cells. J Biol Chem 290(5): 3137-3148.
    • (2015) J Biol Chem , vol.290 , Issue.5 , pp. 3137-3148
    • Goupil, E.1
  • 67
    • 36448968578 scopus 로고    scopus 로고
    • Allosteric modulation of heterodimeric G-protein-coupled receptors
    • Milligan G, Smith NJ (2007) Allosteric modulation of heterodimeric G-protein-coupled receptors. Trends Pharmacol Sci 28(12):615-620.
    • (2007) Trends Pharmacol Sci , vol.28 , Issue.12 , pp. 615-620
    • Milligan, G.1    Smith, N.J.2
  • 68
    • 60249098735 scopus 로고    scopus 로고
    • Building a new conceptual framework for receptor heteromers
    • Ferré S, et al. (2009) Building a new conceptual framework for receptor heteromers. Nat Chem Biol 5(3):131-134.
    • (2009) Nat Chem Biol , vol.5 , Issue.3 , pp. 131-134
    • Ferré, S.1
  • 69
    • 84858609378 scopus 로고    scopus 로고
    • Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G proteincoupled receptor signaling
    • Malik R, Soh UJ, Trejo J, Marchese A (2012) Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G proteincoupled receptor signaling. J Biol Chem 287(12):9013-9027.
    • (2012) J Biol Chem , vol.287 , Issue.12 , pp. 9013-9027
    • Malik, R.1    Soh, U.J.2    Trejo, J.3    Marchese, A.4
  • 70
    • 70350452558 scopus 로고    scopus 로고
    • Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels
    • may account for differences in cardiovascular risk profiles.
    • Brueggemann LI, Mackie AR, Mani BK, Cribbs LL, Byron KL (2009) Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles. Mol Pharmacol 76(5):1053-1061.
    • (2009) Mol Pharmacol , vol.76 , Issue.5 , pp. 1053-1061
    • Brueggemann, L.I.1    Mackie, A.R.2    Mani, B.K.3    Cribbs, L.L.4    Byron, K.L.5
  • 71
    • 34147101914 scopus 로고    scopus 로고
    • Vasopressin-induced vasoconstriction: Two concen-tration-dependent signaling pathways
    • Henderson KK, Byron KL (2007) Vasopressin-induced vasoconstriction: Two concen-tration-dependent signaling pathways. J Appl Physiol (1985) 102(4):1402-1409.
    • (2007) J Appl Physiol 1985 , vol.102 , Issue.4 , pp. 1402-1409
    • Henderson, K.K.1    Byron, K.L.2
  • 72
    • 42449127582 scopus 로고    scopus 로고
    • Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance
    • Mackie AR, et al. (2008) Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance. J Pharmacol Exp Ther 325(2):475-483.
    • (2008) J Pharmacol Exp Ther , vol.325 , Issue.2 , pp. 475-483
    • Mackie, A.R.1
  • 73
    • 33745173829 scopus 로고    scopus 로고
    • Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)
    • Veldkamp CT, Seibert C, Peterson FC, Sakmar TP, Volkman BF (2006) Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12). J Mol Biol 359(5):1400-1409.
    • (2006) J Mol Biol , vol.359 , Issue.5 , pp. 1400-1409
    • Veldkamp, C.T.1    Seibert, C.2    Peterson, F.C.3    Sakmar, T.P.4    Volkman, B.F.5
  • 74
    • 63449099882 scopus 로고    scopus 로고
    • Differences in lysine pKa values
    • may be used to improve NMR signal dispersion in reductively methylated proteins.
    • Abraham SJ, Kobayashi T, Solaro RJ, Gaponenko V (2009) Differences in lysine pKa values may be used to improve NMR signal dispersion in reductively methylated proteins. J Biomol NMR 43(4):239-246.
    • (2009) J Biomol NMR , vol.43 , Issue.4 , pp. 239-246
    • Abraham, S.J.1    Kobayashi, T.2    Solaro, R.J.3    Gaponenko, V.4
  • 75
    • 77954626403 scopus 로고    scopus 로고
    • Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4
    • Malik R, Marchese A (2010) Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. Mol Biol Cell 21(14):2529-2541.
    • (2010) Mol Biol Cell , vol.21 , Issue.14 , pp. 2529-2541
    • Malik, R.1    Marchese, A.2
  • 76
    • 77952694865 scopus 로고    scopus 로고
    • P62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha
    • O'Connor C, et al. (2010) p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha. J Virol 84(12):5997-6006.
    • (2010) J Virol , vol.84 , Issue.12 , pp. 5997-6006
    • O'Connor, C.1
  • 77
    • 79953749322 scopus 로고    scopus 로고
    • Self-organizing optic-cup morphogenesis in three-dimensional culture
    • Eiraku M, et al. (2011) Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472(7341):51-56.
    • (2011) Nature , vol.472 , Issue.7341 , pp. 51-56
    • Eiraku, M.1
  • 78
    • 84879247089 scopus 로고    scopus 로고
    • Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification
    • Tripathi A, et al. (2013) Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification. Biochemistry 52(24): 4184-4192.
    • (2013) Biochemistry , vol.52 , Issue.24 , pp. 4184-4192
    • Tripathi, A.1


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