Heterogeneity in mechanisms influencing glucocorticoid sensitivity: The need for a systems biology approach to treatment of glucocorticoid-resistant inflammation

Pharmacology and Therapeutics

Volumn 150, Issue , 2015, Pages 81-93

  Keenan, Christine R ^a   Radojicic, Danica ^a   Li, Meina ^a   Radwan, Asmaa ^a   Stewart, Alastair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Airways; Asthma; COPD; Cytokines; Idiopathic pulmonary fibrosis; Innate host defence

Indexed keywords

ANTIINFLAMMATORY AGENT; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR;

ANIMAL; ASTHMA; BIOAVAILABILITY; GENETICS; HUMAN; INFLAMMATION; METABOLISM; PATHOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY FIBROSIS; SEPSIS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TRANSCRIPTION INITIATION; TREATMENT FAILURE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BIOLOGICAL AVAILABILITY; GLUCOCORTICOIDS; HUMANS; INFLAMMATION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY FIBROSIS; RECEPTORS, GLUCOCORTICOID; SEPSIS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TRANSCRIPTIONAL ACTIVATION; TREATMENT FAILURE;

EID: 84939995733     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2015.01.006     Document Type: Review

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