Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

Journal of Allergy and Clinical Immunology

Volumn 131, Issue 3, 2013, Pages 636-645

  Barnes, Peter J ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Glucocorticoid receptor; histone deacetylase; p38 mitogen activated protein kinase; phosphoinositide 3 kinase; protein phosphatase; theophylline

Indexed keywords

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; CURCUMIN; DEXAMETHASONE; FORMOTEROL; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; HISTONE DEACETYLASE 2; MACROLIDE; MACROPHAGE MIGRATION INHIBITION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NORTRIPTYLINE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHOINOSITIDE 3 KINASE DELTA INHIBITOR; PREDNISONE; PROTEIN PHOSPHATASE A2; ROFLUMILAST; SALMETEROL; STRESS ACTIVATED PROTEIN KINASE 1; SULFORAPHANE; THEOPHYLLINE; TRANSCRIPTION FACTOR AP 1; TRIAMCINOLONE ACETONIDE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CYTOKINE RELEASE; DIARRHEA; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; FORCED EXPIRATORY VOLUME; GENE REPRESSION; GENETIC SUSCEPTIBILITY; HEADACHE; HISTONE ACETYLATION; HUMAN; LOW DRUG DOSE; LUNG FUNCTION; NAUSEA; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SMOKING; TREATMENT RESPONSE;

ADRENAL CORTEX HORMONES; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; DRUG RESISTANCE; HUMANS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84875225940     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.12.1564     Document Type: Review

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