메뉴 건너뛰기




Volumn 16, Issue 6, 2006, Pages 301-307

Glucocorticoid receptor isoforms generate transcription specificity

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ALPHA; TRANSCRIPTOME;

EID: 33745090483     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2006.04.005     Document Type: Review
Times cited : (203)

References (47)
  • 1
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids - new mechanisms for old drugs
    • Rhen T., and Cidlowski J.A. Antiinflammatory action of glucocorticoids - new mechanisms for old drugs. N. Engl. J. Med. 353 (2005) 1711-1723
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 2
    • 18044366957 scopus 로고    scopus 로고
    • Evaluation of steroid receptor function by gene targeting in mice
    • Wintermantel T.M., et al. Evaluation of steroid receptor function by gene targeting in mice. J. Steroid Biochem. Mol. Biol. 93 (2005) 107-112
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.93 , pp. 107-112
    • Wintermantel, T.M.1
  • 3
    • 0041386422 scopus 로고    scopus 로고
    • Tissue glucocorticoid resistance/hypersensitivity syndromes
    • Kino T., et al. Tissue glucocorticoid resistance/hypersensitivity syndromes. J. Steroid Biochem. Mol. Biol. 85 (2003) 457-467
    • (2003) J. Steroid Biochem. Mol. Biol. , vol.85 , pp. 457-467
    • Kino, T.1
  • 4
    • 3042831099 scopus 로고    scopus 로고
    • The origin and functions of multiple human glucocorticoid receptor isoforms
    • Lu N.Z., and Cidlowski J.A. The origin and functions of multiple human glucocorticoid receptor isoforms. Ann. N. Y. Acad. Sci. 1024 (2004) 102-123
    • (2004) Ann. N. Y. Acad. Sci. , vol.1024 , pp. 102-123
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 5
    • 14744303696 scopus 로고    scopus 로고
    • Expanding functional diversity of the coactivators
    • Lonard D.M., and O'Malley B.W. Expanding functional diversity of the coactivators. Trends Biochem. Sci. 30 (2005) 126-132
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 126-132
    • Lonard, D.M.1    O'Malley, B.W.2
  • 6
    • 0036135774 scopus 로고    scopus 로고
    • Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
    • Galon J., et al. Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J. 16 (2002) 61-71
    • (2002) FASEB J. , vol.16 , pp. 61-71
    • Galon, J.1
  • 7
    • 20844437424 scopus 로고    scopus 로고
    • Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes
    • Lu N.Z., and Cidlowski J.A. Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes. Mol. Cell 18 (2005) 331-342
    • (2005) Mol. Cell , vol.18 , pp. 331-342
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 8
    • 18244370834 scopus 로고    scopus 로고
    • Differential gene expression profile of glucocorticoids, testosterone, and dehydroepiandrosterone in human cells
    • Maurer M., et al. Differential gene expression profile of glucocorticoids, testosterone, and dehydroepiandrosterone in human cells. Horm. Metab. Res. 33 (2001) 691-695
    • (2001) Horm. Metab. Res. , vol.33 , pp. 691-695
    • Maurer, M.1
  • 9
    • 0035913191 scopus 로고    scopus 로고
    • Expression profiling of glucocorticoid-treated T-ALL cell lines: rapid repression of multiple genes involved in RNA-, protein- and nucleotide synthesis
    • Obexer P., et al. Expression profiling of glucocorticoid-treated T-ALL cell lines: rapid repression of multiple genes involved in RNA-, protein- and nucleotide synthesis. Oncogene 20 (2001) 4324-4336
    • (2001) Oncogene , vol.20 , pp. 4324-4336
    • Obexer, P.1
  • 10
    • 0035088322 scopus 로고    scopus 로고
    • Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis
    • Tonko M., et al. Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis. FASEB J. 15 (2001) 693-699
    • (2001) FASEB J. , vol.15 , pp. 693-699
    • Tonko, M.1
  • 11
    • 85047699977 scopus 로고    scopus 로고
    • Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays
    • Chauhan D., et al. Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays. Oncogene 21 (2002) 1346-1358
    • (2002) Oncogene , vol.21 , pp. 1346-1358
    • Chauhan, D.1
  • 12
    • 0036088335 scopus 로고    scopus 로고
    • Analysis of gene expression patterns during glucocorticoid-induced apoptosis using oligonucleotide arrays
    • Yoshida N.L., et al. Analysis of gene expression patterns during glucocorticoid-induced apoptosis using oligonucleotide arrays. Biochem. Biophys. Res. Commun. 293 (2002) 1254-1261
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , pp. 1254-1261
    • Yoshida, N.L.1
  • 13
    • 0038404712 scopus 로고    scopus 로고
    • Glucocorticoid regulation of human eosinophil gene expression
    • Chauhan S., et al. Glucocorticoid regulation of human eosinophil gene expression. J. Steroid Biochem. Mol. Biol. 84 (2003) 441-452
    • (2003) J. Steroid Biochem. Mol. Biol. , vol.84 , pp. 441-452
    • Chauhan, S.1
  • 14
    • 0038362418 scopus 로고    scopus 로고
    • Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis
    • Medh R.D., et al. Gene expression profile of human lymphoid CEM cells sensitive and resistant to glucocorticoid-evoked apoptosis. Genomics 81 (2003) 543-555
    • (2003) Genomics , vol.81 , pp. 543-555
    • Medh, R.D.1
  • 15
    • 0037226583 scopus 로고    scopus 로고
    • Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells
    • Planey S.L., et al. Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells. Cancer Res. 63 (2003) 172-178
    • (2003) Cancer Res. , vol.63 , pp. 172-178
    • Planey, S.L.1
  • 16
    • 0037592259 scopus 로고    scopus 로고
    • Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis
    • Wang Z., et al. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J. Biol. Chem. 278 (2003) 23861-23867
    • (2003) J. Biol. Chem. , vol.278 , pp. 23861-23867
    • Wang, Z.1
  • 17
    • 0042978652 scopus 로고    scopus 로고
    • Gene networks in glucocorticoid-evoked apoptosis of leukemic cells
    • Webb M.S., et al. Gene networks in glucocorticoid-evoked apoptosis of leukemic cells. J. Steroid Biochem. Mol. Biol. 85 (2003) 183-193
    • (2003) J. Steroid Biochem. Mol. Biol. , vol.85 , pp. 183-193
    • Webb, M.S.1
  • 18
    • 4444276363 scopus 로고    scopus 로고
    • Gene expression profiling of glucocorticoid-inhibited osteoblasts
    • Leclerc N., et al. Gene expression profiling of glucocorticoid-inhibited osteoblasts. J. Mol. Endocrinol. 33 (2004) 175-193
    • (2004) J. Mol. Endocrinol. , vol.33 , pp. 175-193
    • Leclerc, N.1
  • 19
    • 8144228848 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes
    • Wang J.C., et al. Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 15603-15608
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 15603-15608
    • Wang, J.C.1
  • 20
    • 17644367860 scopus 로고    scopus 로고
    • Immediate early genes of glucocorticoid action on the developing intestine
    • Agbemafle B.M., et al. Immediate early genes of glucocorticoid action on the developing intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 288 (2005) G897-G906
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.288
    • Agbemafle, B.M.1
  • 21
    • 27944467837 scopus 로고    scopus 로고
    • Global gene profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells
    • Gupta V., et al. Global gene profiling reveals novel glucocorticoid induced changes in gene expression of human lens epithelial cells. Mol. Vis. 11 (2005) 1018-1040
    • (2005) Mol. Vis. , vol.11 , pp. 1018-1040
    • Gupta, V.1
  • 22
    • 0032611267 scopus 로고    scopus 로고
    • 11 β-hydroxysteroid dehydrogenase
    • Stewart P.M., and Krozowski Z.S. 11 β-hydroxysteroid dehydrogenase. Vitam. Horm. 57 (1999) 249-324
    • (1999) Vitam. Horm. , vol.57 , pp. 249-324
    • Stewart, P.M.1    Krozowski, Z.S.2
  • 23
    • 4043077286 scopus 로고    scopus 로고
    • 11-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response
    • Tomlinson J.W., et al. 11-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr. Rev. 25 (2004) 831-866
    • (2004) Endocr. Rev. , vol.25 , pp. 831-866
    • Tomlinson, J.W.1
  • 24
    • 0029013333 scopus 로고
    • LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones
    • Kralli A., et al. LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 4701-4705
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 4701-4705
    • Kralli, A.1
  • 25
    • 3242892659 scopus 로고    scopus 로고
    • Nuclear receptor recruitment of histone-modifying enzymes to target gene promoters
    • Tsai C.C., and Fondell J.D. Nuclear receptor recruitment of histone-modifying enzymes to target gene promoters. Vitam. Horm. 68 (2004) 93-122
    • (2004) Vitam. Horm. , vol.68 , pp. 93-122
    • Tsai, C.C.1    Fondell, J.D.2
  • 26
    • 0033600936 scopus 로고    scopus 로고
    • The dominant negative activity of the human glucocorticoid receptor βisoform. Specificity and mechanisms of action
    • Oakley R.H., et al. The dominant negative activity of the human glucocorticoid receptor βisoform. Specificity and mechanisms of action. J. Biol. Chem. 274 (1999) 27857-27866
    • (1999) J. Biol. Chem. , vol.274 , pp. 27857-27866
    • Oakley, R.H.1
  • 27
    • 0037979126 scopus 로고    scopus 로고
    • Molecular origins for the dominant negative function of human glucocorticoid receptorβ
    • Yudt M.R., et al. Molecular origins for the dominant negative function of human glucocorticoid receptorβ. Mol. Cell. Biol. 23 (2003) 4319-4330
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4319-4330
    • Yudt, M.R.1
  • 28
    • 11244329291 scopus 로고    scopus 로고
    • The human glucocorticoid receptor (hGR) β isoform suppresses the transcriptional activity of hGRalpha by interfering with formation of active coactivator complexes
    • Charmandari E., et al. The human glucocorticoid receptor (hGR) β isoform suppresses the transcriptional activity of hGRalpha by interfering with formation of active coactivator complexes. Mol. Endocrinol. 19 (2005) 52-64
    • (2005) Mol. Endocrinol. , vol.19 , pp. 52-64
    • Charmandari, E.1
  • 29
    • 0036306275 scopus 로고    scopus 로고
    • Mechanisms of corticosteroid resistance in rheumatoid arthritis: a putative role for the corticosteroid receptor β isoform
    • Chikanza I.C. Mechanisms of corticosteroid resistance in rheumatoid arthritis: a putative role for the corticosteroid receptor β isoform. Ann. N. Y. Acad. Sci. 966 (2002) 39-48
    • (2002) Ann. N. Y. Acad. Sci. , vol.966 , pp. 39-48
    • Chikanza, I.C.1
  • 30
    • 0034058875 scopus 로고    scopus 로고
    • Expression of glucocorticoid receptor β in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis
    • Honda M., et al. Expression of glucocorticoid receptor β in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis. Gastroenterology 118 (2000) 859-866
    • (2000) Gastroenterology , vol.118 , pp. 859-866
    • Honda, M.1
  • 31
    • 0027165727 scopus 로고
    • Mutant glucocorticoid receptors in lymphoma
    • Ip M.M., et al. Mutant glucocorticoid receptors in lymphoma. Ann. N. Y. Acad. Sci. 684 (1993) 94-115
    • (1993) Ann. N. Y. Acad. Sci. , vol.684 , pp. 94-115
    • Ip, M.M.1
  • 32
    • 0025775736 scopus 로고
    • Identification of phosphorylated sites in the mouse glucocorticoid receptor
    • Bodwell J.E., et al. Identification of phosphorylated sites in the mouse glucocorticoid receptor. J. Biol. Chem. 266 (1991) 7549-7555
    • (1991) J. Biol. Chem. , vol.266 , pp. 7549-7555
    • Bodwell, J.E.1
  • 33
    • 0030900729 scopus 로고    scopus 로고
    • Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein
    • Webster J.C., et al. Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein. J. Biol. Chem. 272 (1997) 9287-9293
    • (1997) J. Biol. Chem. , vol.272 , pp. 9287-9293
    • Webster, J.C.1
  • 34
    • 0037135596 scopus 로고    scopus 로고
    • Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo
    • Wang Z., et al. Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo. J. Biol. Chem. 277 (2002) 26573-26580
    • (2002) J. Biol. Chem. , vol.277 , pp. 26573-26580
    • Wang, Z.1
  • 35
    • 0035900780 scopus 로고    scopus 로고
    • Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
    • Wallace A.D., and Cidlowski J.A. Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. J. Biol. Chem. 276 (2001) 42714-42721
    • (2001) J. Biol. Chem. , vol.276 , pp. 42714-42721
    • Wallace, A.D.1    Cidlowski, J.A.2
  • 36
    • 0037066790 scopus 로고    scopus 로고
    • Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors
    • Kaul S., et al. Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors. J. Biol. Chem. 277 (2002) 12541-12549
    • (2002) J. Biol. Chem. , vol.277 , pp. 12541-12549
    • Kaul, S.1
  • 37
    • 0035883863 scopus 로고    scopus 로고
    • Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2
    • Sengupta S., and Wasylyk B. Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2. Genes Dev. 15 (2001) 2367-2380
    • (2001) Genes Dev. , vol.15 , pp. 2367-2380
    • Sengupta, S.1    Wasylyk, B.2
  • 38
    • 0035146685 scopus 로고    scopus 로고
    • The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
    • Connell P., et al. The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. Nat. Cell Biol. 3 (2001) 93-96
    • (2001) Nat. Cell Biol. , vol.3 , pp. 93-96
    • Connell, P.1
  • 39
    • 0036847208 scopus 로고    scopus 로고
    • Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor
    • Tian S., et al. Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. Biochem. J. 367 (2002) 907-911
    • (2002) Biochem. J. , vol.367 , pp. 907-911
    • Tian, S.1
  • 40
    • 0036721526 scopus 로고    scopus 로고
    • Potentiation of glucocorticoid receptor transcriptional activity by sumoylation
    • Le Drean Y., et al. Potentiation of glucocorticoid receptor transcriptional activity by sumoylation. Endocrinology 143 (2002) 3482-3489
    • (2002) Endocrinology , vol.143 , pp. 3482-3489
    • Le Drean, Y.1
  • 41
    • 0347994898 scopus 로고    scopus 로고
    • Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy
    • Holmstrom S., et al. Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 15758-15763
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 15758-15763
    • Holmstrom, S.1
  • 42
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
    • Ito K., et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression. J. Exp. Med. 203 (2006) 7-13
    • (2006) J. Exp. Med. , vol.203 , pp. 7-13
    • Ito, K.1
  • 43
    • 0037121050 scopus 로고    scopus 로고
    • Pushing the limits of the scanning mechanism for initiation of translation
    • Kozak M. Pushing the limits of the scanning mechanism for initiation of translation. Gene 299 (2002) 1-34
    • (2002) Gene , vol.299 , pp. 1-34
    • Kozak, M.1
  • 44
    • 0034283016 scopus 로고    scopus 로고
    • Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1
    • Flouriot G., et al. Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1. EMBO J. 19 (2000) 4688-4700
    • (2000) EMBO J. , vol.19 , pp. 4688-4700
    • Flouriot, G.1
  • 45
    • 2342463593 scopus 로고    scopus 로고
    • Human mineralocorticoid receptor A and B protein forms produced by alternative translation sites display different transcriptional activities
    • Pascual-Le Tallec L., et al. Human mineralocorticoid receptor A and B protein forms produced by alternative translation sites display different transcriptional activities. Eur. J. Endocrinol. 150 (2004) 585-590
    • (2004) Eur. J. Endocrinol. , vol.150 , pp. 585-590
    • Pascual-Le Tallec, L.1
  • 46
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium
    • International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 431 (2004) 931-945
    • (2004) Nature , vol.431 , pp. 931-945
  • 47
    • 22344454972 scopus 로고    scopus 로고
    • G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus
    • Kino T., et al. G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus. J. Cell Biol. 169 (2005) 885-896
    • (2005) J. Cell Biol. , vol.169 , pp. 885-896
    • Kino, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.