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Volumn 127, Issue 4, 1999, Pages 1003-1011

Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: Preferential targetting of NF-κB and lack of I-κB involvement

Author keywords

Cross coupling; Glucocorticoids; GM CSF; Inflammation; NF B; RU486

Indexed keywords

BUDESONIDE; DEXAMETHASONE; FLUTICASONE PROPIONATE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MIFEPRISTONE; STEROID; TIPREDANE;

EID: 0032982717     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702613     Document Type: Article
Times cited : (105)

References (28)
  • 2
    • 0028916199 scopus 로고
    • Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma
    • ADCOCK, I.M., LANE, S.J., BROWN, C.R., PETERS, M.J., LEE, T.H. & BARNES, P.J. (1995). Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma. J. Immunol., 154, 3500-3505.
    • (1995) J. Immunol. , vol.154 , pp. 3500-3505
    • Adcock, I.M.1    Lane, S.J.2    Brown, C.R.3    Peters, M.J.4    Lee, T.H.5    Barnes, P.J.6
  • 3
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • AUPHAN, N., DIDONATO, J.A., ROSETTE, C., HELMBERG, A. & KARIN, M. (1995). Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science, 270, 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 4
    • 0028956973 scopus 로고
    • Inhaled glucocorticoids for asthma
    • BARNES, P.J. (1995). Inhaled glucocorticoids for asthma. N. Engl. J. Med., 332, 868-875.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 868-875
    • Barnes, P.J.1
  • 5
    • 0027494730 scopus 로고
    • Anti-inflammatory actions of steroids: Molecular mechanisms
    • BARNES, P.J. & ADCOCK, I. (1993). Anti-inflammatory actions of steroids: molecular mechanisms. Trends. Pharmacol. Sci., 14, 436-441.
    • (1993) Trends. Pharmacol. Sci. , vol.14 , pp. 436-441
    • Barnes, P.J.1    Adcock, I.2
  • 6
    • 0029929071 scopus 로고    scopus 로고
    • Control of transcription by steroid hormones
    • BEATO, M., TRUSS, M. & CHAVEZ, S. (1996). Control of transcription by steroid hormones. Ann. N. Y. Acad. Sci., 784, 93-123.
    • (1996) Ann. N. Y. Acad. Sci. , vol.784 , pp. 93-123
    • Beato, M.1    Truss, M.2    Chavez, S.3
  • 7
    • 0029820720 scopus 로고    scopus 로고
    • Cytokine modulation by glucocorticoids: Mechanisms and actions in cellular studies
    • BRATTSAND, R. & LINDEN, M. (1996). Cytokine modulation by glucocorticoids: mechanisms and actions in cellular studies. Aliment. Pharmacol. Ther., 10 (Suppl 2), 81-90.
    • (1996) Aliment. Pharmacol. Ther. , vol.10 , Issue.SUPPL. 2 , pp. 81-90
    • Brattsand, R.1    Linden, M.2
  • 8
    • 0029778179 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of Ikappa Balpha synthesis
    • BROSTJAN, C., ANRATHER, J., CSIZMADIA, V., STROKA, D., SOARES, M., BACK, F.H. & WINKLER, H. (1996). Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of Ikappa Balpha synthesis. J. Biol. Chem., 271, 19612-19616.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19612-19616
    • Brostjan, C.1    Anrather, J.2    Csizmadia, V.3    Stroka, D.4    Soares, M.5    Back, F.H.6    Winkler, H.7
  • 9
    • 0023819348 scopus 로고
    • Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids
    • COLLINS, S., CARON, M.G. & LEFKOWITZ, R.J. (1988). Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. J. Biol. Chem., 263, 9067-9070.
    • (1988) J. Biol. Chem. , vol.263 , pp. 9067-9070
    • Collins, S.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 10
    • 0025236734 scopus 로고
    • Binding and inhibition studies on lipocortins using phosphatidylcholine vesicles and phospholipasce A2 from snake venom, pancreas, and a macrophage-like cell line
    • DAVIDSON, F.F., LISTER, M.D. & DENNIS, E.A. (1990). Binding and inhibition studies on lipocortins using phosphatidylcholine vesicles and phospholipasce A2 from snake venom, pancreas, and a macrophage-like cell line. J. Biol. Chem., 265, 5602-5609.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5602-5609
    • Davidson, F.F.1    Lister, M.D.2    Dennis, E.A.3
  • 11
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • FLOWER, R.J. & ROTHWELL, N.J. (1994). Lipocortin-1: cellular mechanisms and clinical relevance. Trends. Pharmacol. Sci., 15, 71-76.
    • (1994) Trends. Pharmacol. Sci. , vol.15 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 12
    • 0030789420 scopus 로고    scopus 로고
    • I-kappaB alpha independent downregulation of NF-kappaB activity by glucocorticoid receptor
    • HECK, S., BENDER, K., KULLMANN, M., GOTTLICHER, M., HERRLICH, P. & CATO, A.C. (1997). I-kappaB alpha independent downregulation of NF-kappaB activity by glucocorticoid receptor. EMBO J., 16, 4698-4707.
    • (1997) EMBO J. , vol.16 , pp. 4698-4707
    • Heck, S.1    Bender, K.2    Kullmann, M.3    Gottlicher, M.4    Herrlich, P.5    Cato, A.C.6
  • 13
    • 0027934108 scopus 로고
    • A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1
    • HECK, S., KULLMANN, M., GAST, A., PONTA, H., RAHMSDORF, H.J., HERRLICH, P. & CATO, A.C. (1994). A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. EMBO J., 13, 4087-4095.
    • (1994) EMBO J. , vol.13 , pp. 4087-4095
    • Heck, S.1    Kullmann, M.2    Gast, A.3    Ponta, H.4    Rahmsdorf, H.J.5    Herrlich, P.6    Cato, A.C.7
  • 14
    • 0030986236 scopus 로고    scopus 로고
    • A signature motif in transcriptional co-activators mediates binding to nuclear receptors
    • HEERY, D.M., KALKHOVEN, E., HOARE, S. & PARKER, M.G. (1997). A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature, 387, 733-736.
    • (1997) Nature , vol.387 , pp. 733-736
    • Heery, D.M.1    Kalkhoven, E.2    Hoare, S.3    Parker, M.G.4
  • 15
    • 0030207894 scopus 로고    scopus 로고
    • Versatile molecular glue. Transcriptional control
    • JANKNECHT, R. & HUNTER, T. (1996). Versatile molecular glue. Transcriptional control. Curr. Biol., 6, 951-954.
    • (1996) Curr. Biol. , vol.6 , pp. 951-954
    • Janknecht, R.1    Hunter, T.2
  • 16
    • 0032524357 scopus 로고    scopus 로고
    • New twists in gene regulation by glucocorticoid receptor: Is DNA binding dispensable?
    • KARIN, M. (1998). New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable? Cell, 93, 487-490.
    • (1998) Cell , vol.93 , pp. 487-490
    • Karin, M.1
  • 17
    • 0029895972 scopus 로고    scopus 로고
    • DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells
    • KOCHETKOVA, M. & SHANNON, M.F. (1996). DNA triplex formation selectively inhibits granulocyte-macrophage colony-stimulating factor gene expression in human T cells. J. Biol. Chem., 271, 14438-14444.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14438-14444
    • Kochetkova, M.1    Shannon, M.F.2
  • 18
    • 0029315090 scopus 로고
    • Bronchial epithelial cell-cytokine interactions in airway inflammation
    • LEVINE, S.J. (1995). Bronchial epithelial cell-cytokine interactions in airway inflammation. J. Investig. Med., 43, 241-249.
    • (1995) J. Investig. Med. , vol.43 , pp. 241-249
    • Levine, S.J.1
  • 19
    • 0030051916 scopus 로고    scopus 로고
    • Superinduction of NF-kappa B by actinomycin D and cycloheximide in epithelial cells
    • NEWTON, R., ADCOCK, I.M. & BARNES, P.J. (1996). Superinduction of NF-kappa B by actinomycin D and cycloheximide in epithelial cells. Biochem. Biophys. Res. Commun., 218, 518-523.
    • (1996) Biochem. Biophys. Res. Commun. , vol.218 , pp. 518-523
    • Newton, R.1    Adcock, I.M.2    Barnes, P.J.3
  • 20
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • PERKINS, N.D., FELZIEN, L.K., BETTS, J.C., LEUNG, K., BEACH, D.H. & NABEL, G.J. (1997). Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science, 275, 523-527.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 21
    • 0030678464 scopus 로고    scopus 로고
    • Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids
    • RAY, K.P., FARROW, S., DALY, M., TALABOT, F. & SEARLE, N. (1997). Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids. Biochem. J., 328, 707-715.
    • (1997) Biochem. J. , vol.328 , pp. 707-715
    • Ray, K.P.1    Farrow, S.2    Daly, M.3    Talabot, F.4    Searle, N.5
  • 22
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • SCHEINMAN, R.I., COGSWELL, P.C., LOFQUIST, A.K. & BALDWIN, JR A.S. (1995a). Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science, 270, 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin A.S., Jr.4
  • 23
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors
    • SCHEINMAN, R.I., GUALBERTO, A., JEWELL, C.M., CIDLOWSKI, J.A. & BALDWIN, JR A.S. (1995b). Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. Mol. Cell Biol., 15, 943-953.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin A.S., Jr.5
  • 24
    • 0032491483 scopus 로고    scopus 로고
    • Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1
    • SHEPPARD, K.A., PHELPS, K.M., WILLIAMS, A.J., THANOS, D., GLASS, C.K., ROSENFELD, M.G., GERRITSEN, M.E. & COLLINS, T. (1998). Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1. J. Biol. Chem., 273, 29291-29294.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29291-29294
    • Sheppard, K.A.1    Phelps, K.M.2    Williams, A.J.3    Thanos, D.4    Glass, C.K.5    Rosenfeld, M.G.6    Gerritsen, M.E.7    Collins, T.8
  • 25
    • 0027224017 scopus 로고
    • Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function
    • STEIN, B., BALDWIN, JR A.S., BALLARD, D.W., GREENE, W.C., ANGEL, P. & HERRLICH, P. (1993). Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J., 12, 3879-3891.
    • (1993) EMBO J. , vol.12 , pp. 3879-3891
    • Stein, B.1    Baldwin A.S., Jr.2    Ballard, D.W.3    Greene, W.C.4    Angel, P.5    Herrlich, P.6
  • 26
    • 0242490975 scopus 로고
    • Synergistic action of the glucocorticoid receptor with transcription factors
    • STRAHLE, U., SCHMID, W. & SCHUTZ, G. (1988). Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J., 7, 3389-3395.
    • (1988) EMBO J. , vol.7 , pp. 3389-3395
    • Strahle, U.1    Schmid, W.2    Schutz, G.3
  • 27
    • 0026316847 scopus 로고
    • Antagonism between retinoic acid receptors and AP-1 : Implications for tumor promotion and inflammation
    • YANG YEN, H.F., ZHANG, X.K., GRAUPNER, G., TZUKERMAN, M., SAKAMOTO, B., KARIN, M. & PFAHL., M. (1991). Antagonism between retinoic acid receptors and AP-1 : implications for tumor promotion and inflammation. New Biol., 3, 1206-1219.
    • (1991) New Biol. , vol.3 , pp. 1206-1219
    • Yang Yen, H.F.1    Zhang, X.K.2    Graupner, G.3    Tzukerman, M.4    Sakamoto, B.5    Karin, M.6    Pfahl, M.7
  • 28
    • 0027400286 scopus 로고
    • Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus
    • ZABEL, U., HENKEL, T., SILVA, M.S. & BAEUERLE, P.A. (1993). Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus. EMBO J., 12, 201-211.
    • (1993) EMBO J. , vol.12 , pp. 201-211
    • Zabel, U.1    Henkel, T.2    Silva, M.S.3    Baeuerle, P.A.4


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