Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

Nature Medicine

Volumn 8, Issue 5, 2002, Pages 473-479

  Hafezi Moghadam, Ali ^b,c,e   Simoncini, Tommaso ^f   Yang, Zequan ^e   Limbourg, Florian P ^a   Plumier, Jean Christophe ^d   Rebsamen, Michela C ^a   Hsieh, Chung Ming ^a   Chui, Dao Shan ^a   Thomas, Kennard L ^b,e   Prorock, Alyson J ^e   Laubach, Victor E ^e   Moskowitz, Michael A ^d   French, Brent A ^e   Ley, Klaus ^e   Liao, James K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION;

ADRENAL CORTEX HORMONES; ANIMALS; AORTA; CARDIOTONIC AGENTS; CELLS, CULTURED; DEXAMETHASONE; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HUMANS; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; POTASSIUM CHLORIDE;

ANIMALIA;

EID: 0036108564     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0502-473     Document Type: Article

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