Concise review: Deconstructing the lung to reveal its regenerative potential

Stem Cells

Volumn 30, Issue 5, 2012, Pages 811-816

  Mcqualter, Jonathan L ^a   Bertoncello, Ivan ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Epithelial regeneration; Lung stem cells; Niche microenvironment

Indexed keywords

ATAXIN 1; CD24 ANTIGEN; CYTOKINE; EPITHELIAL CELL ADHESION MOLECULE; PROTEIN P63;

ENDOTHELIAL PROGENITOR CELL; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; LUNG DISEASE; LUNG STRUCTURE; MESENCHYMAL STEM CELL; MICROENVIRONMENT; NONHUMAN; PROTEIN EXPRESSION; REVIEW; STEM CELL NICHE;

ADULT; ADULT STEM CELLS; ANIMALS; CELL LINEAGE; CYTOKINES; ENDOTHELIAL CELLS; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; HUMANS; LUNG; MESENCHYMAL STEM CELLS; MICE; REGENERATIVE MEDICINE;

ANIMALIA;

EID: 84860513926     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1055     Document Type: Review

References (61)

1. Siniscalco D, Sullo N, Maione S et al. Stem cell therapy: The great promise in lung disease. Ther Adv Respir Dis 2008;2:173-177. (Pubitemid 351818742)
2. Borthwick DW, Shahbazian M, Krantz QT et al. Evidence for stemcell niches in the tracheal epithelium. Am J Respir Cell Mol Biol 2001;24:662-670. (Pubitemid 32550587)
3. Hong KU, Reynolds SD, Watkins S et al. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol 2004;164:577-588. (Pubitemid 38364673)
4. Rock JR, Onaitis MW, Rawlins EL et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci USA 2009;106:12771-12775.
5. Cole BB, Smith RW, Jenkins KM et al. Tracheal basal cells: A facultative progenitor cell pool. Am J Pathol 2010;177:362-376.
6. Hegab AE, Ha VL, Gilbert JL et al. Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential. Stem Cells 2011;29:1283-1293.
7. Reynolds SD, Giangreco A, Power JH et al. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol 2000;156:269-278. (Pubitemid 30644460)
8. Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 2002;161:173-182. (Pubitemid 34760783)
9. Rawlins EL, Clark CP, Xue Y et al. The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development 2009;136:3741-3745.
10. Morimoto M, Liu Z, Cheng HT et al. Canonical notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci 2010;123:213-224.
11. Tsao PN, Vasconcelos M, Izvolsky KI et al. Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development 2009;136:2297-2307.
12. Kim CF, Jackson EL, Woolfenden AE et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005; 121:823-835. (Pubitemid 40806415)
13. Nolen-Walston RD, Kim CF, Mazan MR et al. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration. Am J Physiol Lung Cell Mol Physiol 2008;294:L1158-L1165.
14. Zacharek SJ, Fillmore CM, Lau AN et al. Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. Cell Stem Cell 2011;9:272-281.
15. Adamson IY, Bowden DH. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen. Lab Invest 1974;30:35-42.
16. Evans MJ, Cabral LJ, Stephens RJ et al. Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2. Exp Mol Pathol 1975;22:142-150.
17. Kumar PA, Hu Y, Yamamoto Y et al. Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 2011;147:525-538.
18. Rawlins EL, Hogan BL. Ciliated epithelial cell lifespan in the mouse trachea and lung. Am J Physiol Lung Cell Mol Physiol 2008;295:L231-L234.
19. Giangreco A, Arwert EN, Rosewell IR et al. Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci USA 2009;106:9286-9291.
20. Teisanu RM, Lagasse E, Whitesides JF et al. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells 2009;27:612-622.
21. McQualter JL, Brouard N, Williams B et al. Endogenous fibroblastic progenitor cells in the adult mouse lung are highly enriched in the Sca-1 positive cell fraction. Stem Cells 2009;27:623-633.
22. Hegab AE, Kubo H, Fujino N et al. Isolation and characterization of murine multipotent lung stem cells. Stem Cells Dev 2010;19:523-536.
23. McQualter JL, Yuen K, Williams B et al. Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung. Proc Natl Acad Sci USA 2010;107:1414-1419.
24. Teisanu RM, Chen H, Matsumoto K et al. Functional analysis of two distinct bronchiolar progenitors during lung injury and repair. Am J Respir Cell Mol Biol 2011;44:794-803.
25. Chapman HA, Li X, Alexander JP et al. Integrin alpha6beta4 identifies an adult distal lung epithelial population with regenerative potential in mice. J Clin Invest 2011;121:2855-2862.
26. Rock JR, Gao X, Xue Y et al. Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell 2011;8:639-648.
27. Yamamoto H, Yun EJ, Gerber HP et al. Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis. Dev Biol 2007;308:44-53. (Pubitemid 47087777)
28. Ding BS, Nolan DJ, Guo P et al. Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell 2011; 147:539-553.
29. Crivellato E. The role of angiogenic growth factors in organogenesis. Int J Dev Biol 2011;55:365-375.
30. Grinnell KL, Harrington EO. Pulmonary endothelial cell interactions with the extracellular matrix. In: Voelkel NF, Rounds S, eds. The Pulmonary Endothelium: Function in Health and Disease. Chichester, West Sussex: Wiley-Blackwell, 2009:51-72.
31. Shannon JM, Deterding RR. Epithelial-mesenchymal interactions in lung development. In: McDonald JA, ed. Lung Biology in Health and Disease. Vol. 100. New York: Marcel Dekker Inc, 1997, pp. 81-118.
32. Bellusci S, Grindley J, Emoto H et al. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 1997;124:4867-4878. (Pubitemid 28016850)
33. Ramasamy SK, Mailleux AA, Gupte VV et al. Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol 2007;307:237-247. (Pubitemid 47008914)
34. Morrisey EE, Hogan BL. Preparing for the first breath: Genetic and cellular mechanisms in lung development. Dev Cell 2010;18:8-23.
35. De Langhe SP, Carraro G, Warburton D et al. Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 2006;299:52-62. (Pubitemid 44550103)
36. Mailleux AA, Kelly R, Veltmaat JM et al. Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development 2005;132: 2157-2166. (Pubitemid 40744475)
37. Shan L, Subramaniam M, Emanuel RL et al. Centrifugal migration of mesenchymal cells in embryonic lung. Dev Dyn 2008;237:750-757. (Pubitemid 351398040)
38. Giangreco A, Shen H, Reynolds SD et al. Molecular phenotype of airway side population cells. Am J Physiol Lung Cell Mol Physiol 2004; 286:L624-L630. (Pubitemid 38365044)
39. Summer R, Fitzsimmons K, Dwyer D et al. Isolation of an adult mouse lung mesenchymal progenitor cell population. Am J Respir Cell Mol Biol 2007;37:152-159. (Pubitemid 47254998)
40. Hoffman AM, Paxson JA, Mazan MR et al. Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung. Stem Cells Dev 2011; 20:1779-1792.
41. Volckaert T, Dill E, Campbell A et al. Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. J Clin Invest 2011;121:4409-4419.
42. Franzdottir SR, Axelsson IT, Arason AJ et al. Airway branching morphogenesis in three dimensional culture. Respir Res 2010;11:162.
43. Timmermans F, Plum J, Yoder MC et al. Endothelial progenitor cells: Identity defined? J Cell Mol Med 2009;13:87-102.
44. Thebaud B, Yoder MC. Pulmonary endothelial progenitor cells. In: Voelkel NF, Rounds S, eds. The Pulmonary Endothelium: Function in Health and Disease. Chichester, West Sussex: Wiley, 2009:203-216.
45. Yoder MC. Progenitor cells in the pulmonary circulation. Proc Am Thorac Soc 2011;8:466-470.
46. King J, Hamil T, Creighton J et al. Structural and functional characteristics of lung macro- and microvascular endothelial cell phenotypes. Microvasc Res 2004;67:139-151. (Pubitemid 38327000)
47. Alvarez DF, Huang L, King JA et al. Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity. Am J Physiol Lung Cell Mol Physiol 2008;294:L419-L430. (Pubitemid 351468841)
48. Schniedermann J, Rennecke M, Buttler K et al. Mouse lung contains endothelial progenitors with high capacity to form blood and lymphatic vessels. BMC Cell Biol 2010;11:50.
49. Balasubramaniam V, Ryan SL, Seedorf GJ et al. Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice. Am J Physiol Lung Cell Mol Physiol 2010;298:L315-L323.
50. Duong HT, Erzurum SC, Asosingh K. Pro-angiogenic hematopoietic progenitor cells and endothelial colony-forming cells in pathological angiogenesis of bronchial and pulmonary circulation. Angiogenesis 2011;14:411-422.
51. Chamoto K, Gibney BC, Lee GS et al. CD34+ progenitor to endothelial cell transition in post-pneumonectomy angiogenesis. Am J Respir Cell Mol Biol 2011 [Epub ahead of print].
52. Hsia CC. Lessons from a canine model of compensatory lung growth. Curr Top Dev Biol 2004;64:17-32. (Pubitemid 39752391)
53. Price AP, England KA, Matson AM et al. Development of a decellularized lung bioreactor system for bioengineering the lung: The matrix reloaded. Tissue Eng Part A 2010;16:2581-2591.
54. Ott HC, Clippinger B, Conrad C et al. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010;16:927-933.
55. Petersen TH, Calle EA, Zhao L et al. Tissue-engineered lungs for in vivo implantation. Science 2010;329:538-541.
56. Baiguera S, Jungebluth P, Burns A et al. Tissue engineered human tracheas for in vivo implantation. Biomaterials 2010;31:8931-8938.
57. Jungebluth P, Alici E, Baiguera S et al. Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: A proof-of-concept study. Lancet 2011;378:1997-2004.
58. Bertoncello I, McQualter JL. Endogenous lung stem cells: What is their potential for use in regenerative medicine? Expert Rev Respir Med 2010;4:349-362.
59. Holmes C, Stanford WL. Concise review: Stem cell antigen-1: Expression, function, and enigma. Stem Cells 2007;25:1339-1347. (Pubitemid 47106000)
60. Kajstura J, Rota M, Hall SR et al. Evidence for human lung stem cells. N Engl J Med 2011;364:1795-1806.
61. Geller GB. Lung stem cells: Looking beyond the hype. Nat Med 2011;17:788-789.