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Volumn 8, Issue 4, 2003, Pages 432-446

The airway epithelium: Structural and functional properties in health and disease

Author keywords

Asthma; Epithelium; Human; Inflammation; Respiratory disease

Indexed keywords

GLUCOCORTICOID;

EID: 0346888342     PISSN: 13237799     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1843.2003.00493.x     Document Type: Review
Times cited : (443)

References (179)
  • 1
    • 0031730041 scopus 로고    scopus 로고
    • Epithelium smooth muscle regulation and interactions
    • Spina D. Epithelium smooth muscle regulation and interactions. Am. J. Respir. Crit. Care Med. 1998; 158: S141-5.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158
    • Spina, D.1
  • 2
    • 0023904418 scopus 로고
    • Proliferation and differentiation in mammalian airway epithelium
    • Ayers MM, Jeffery PK. Proliferation and differentiation in mammalian airway epithelium. Eur. Respir. J. 1988; 1: 58-80.
    • (1988) Eur. Respir. J. , vol.1 , pp. 58-80
    • Ayers, M.M.1    Jeffery, P.K.2
  • 4
    • 0020544649 scopus 로고
    • Morphologic features of airway surface epithelial cells and glands
    • Jeffery PK. Morphologic features of airway surface epithelial cells and glands. Am. Rev. Respir. Dis. 1983; 128: S14-20.
    • (1983) Am. Rev. Respir. Dis. , vol.128
    • Jeffery, P.K.1
  • 5
    • 0025911239 scopus 로고
    • Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease
    • discussion 1161
    • Jeffery PK. Morphology of the airway wall in asthma and in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 1991; 143: 1152-8 (discussion 1161).
    • (1991) Am. Rev. Respir. Dis. , vol.143 , pp. 1152-1158
    • Jeffery, P.K.1
  • 6
    • 0021200147 scopus 로고
    • Goblet and Clara cells of human distal airways: Evidence for smoking induced changes in their numbers
    • Lumsden AB, McLean A, Lamb D. Goblet and Clara cells of human distal airways: evidence for smoking induced changes in their numbers. Thorax 1984; 39: 844-9.
    • (1984) Thorax , vol.39 , pp. 844-849
    • Lumsden, A.B.1    McLean, A.2    Lamb, D.3
  • 7
    • 0023761241 scopus 로고
    • The role of basal cells in adhesion of columnar epithelium to airway basement membrane
    • Evans MJ, Plopper CG. The role of basal cells in adhesion of columnar epithelium to airway basement membrane. Am. Rev. Respir. Dis. 1988; 138: 481-3.
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 481-483
    • Evans, M.J.1    Plopper, C.G.2
  • 8
    • 0027286098 scopus 로고
    • Identification of serous-like cells in the surface epithelium of human bronchioles
    • Rogers AV, Dewar A, Corrin B, Jeffery PK. Identification of serous-like cells in the surface epithelium of human bronchioles. Eur. Respir. J. 1993; 6: 498-504.
    • (1993) Eur. Respir. J. , vol.6 , pp. 498-504
    • Rogers, A.V.1    Dewar, A.2    Corrin, B.3    Jeffery, P.K.4
  • 10
    • 0031574443 scopus 로고    scopus 로고
    • Isolation and characterization of basal cells from human upper respiratory epithelium
    • Hicks W Jr, Hall L 3rd, Sigurdson L et al. Isolation and characterization of basal cells from human upper respiratory epithelium. Exp. Cell Res. 1997; 237: 357-63.
    • (1997) Exp. Cell Res. , vol.237 , pp. 357-363
    • Hicks Jr., W.1    Hall III, L.2    Sigurdson, L.3
  • 12
    • 0031862237 scopus 로고    scopus 로고
    • Number and proliferation of basal and parabasal cells in normal human airway epithelium
    • Boers JE, Ambergen AW, Thunnissen FB. Number and proliferation of basal and parabasal cells in normal human airway epithelium. Am. J. Respir. Crit. Care Med. 1998; 157: 2000-6.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 2000-2006
    • Boers, J.E.1    Ambergen, A.W.2    Thunnissen, F.B.3
  • 13
    • 0022620754 scopus 로고
    • Ultra-structural localization of bronchial antileukoprotease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies
    • De Water R, Willems LN, Van Muijen GN et al. Ultra-structural localization of bronchial antileukoprotease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies. Am. Rev. Respir. Dis. 1986; 133: 882-90.
    • (1986) Am. Rev. Respir. Dis. , vol.133 , pp. 882-890
    • De Water, R.1    Willems, L.N.2    Van Muijen, G.N.3
  • 14
    • 0034974148 scopus 로고    scopus 로고
    • Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion
    • Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR. Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am. J. Respir. Cell Mol. Biol. 2001; 24: 671-81.
    • (2001) Am. J. Respir. Cell Mol. Biol. , vol.24 , pp. 671-681
    • Hong, K.U.1    Reynolds, S.D.2    Giangreco, A.3    Hurley, C.M.4    Stripp, B.R.5
  • 16
    • 0023790445 scopus 로고
    • Neuroendocrine cell populations in normal human lungs: A quantitative study
    • Gosney JR, Sissons MC, Allibone RO. Neuroendocrine cell populations in normal human lungs: a quantitative study. Thorax 1988; 43: 878-82.
    • (1988) Thorax , vol.43 , pp. 878-882
    • Gosney, J.R.1    Sissons, M.C.2    Allibone, R.O.3
  • 18
    • 26344455967 scopus 로고    scopus 로고
    • A confocal microscopy study of pulmonary neuroendocrine cells in human adult airway epithelium
    • Weichselbaum M, Sparrow MP, Thompson PJ, Knight DA. A confocal microscopy study of pulmonary neuroendocrine cells in human adult airway epithelium (abstract). Respirology 2002; 7 (Suppl.): A32.
    • (2002) Respirology , vol.7 , Issue.SUPPL.
    • Weichselbaum, M.1    Sparrow, M.P.2    Thompson, P.J.3    Knight, D.A.4
  • 19
    • 0027327956 scopus 로고
    • Oxygen sensing in airway chemoreceptors
    • Youngson C, Nurse C, Yeger H, Cutz E. Oxygen sensing in airway chemoreceptors. Nature 1993; 365: 153-5.
    • (1993) Nature , vol.365 , pp. 153-155
    • Youngson, C.1    Nurse, C.2    Yeger, H.3    Cutz, E.4
  • 20
    • 0033875885 scopus 로고    scopus 로고
    • Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration
    • Reynolds SD, Giangreco A, Power JH, Stripp BR. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am. J. Pathol. 2000; 156: 269-78.
    • (2000) Am. J. Pathol. , vol.156 , pp. 269-278
    • Reynolds, S.D.1    Giangreco, A.2    Power, J.H.3    Stripp, B.R.4
  • 21
    • 0027195465 scopus 로고
    • Neuroendocrine cells and nerves of the lung
    • discussion 85-6
    • Adriaensen D, Scheuermann DW. Neuroendocrine cells and nerves of the lung. Anat. Rec. 1993; 236: 70-85 (discussion 85-6).
    • (1993) Anat. Rec. , vol.236 , pp. 70-85
    • Adriaensen, D.1    Scheuermann, D.W.2
  • 22
    • 0036840479 scopus 로고    scopus 로고
    • Three-dimensional mapping of sensory innervation with substance p in porcine bronchial mucosa: Comparison with human airways
    • Lamb JP, Sparrow MP. Three-dimensional mapping of sensory innervation with substance p in porcine bronchial mucosa: comparison with human airways. Am. J. Respir. Crit. Care Med. 2002; 166: 1269-81.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , pp. 1269-1281
    • Lamb, J.P.1    Sparrow, M.P.2
  • 24
    • 0025762391 scopus 로고
    • Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways
    • Schon-Hegrad MA, Oliver J, McMenamin PG, Holt PG. Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J. Exp. Med. 1991; 173: 1345-56.
    • (1991) J. Exp. Med. , vol.173 , pp. 1345-1356
    • Schon-Hegrad, M.A.1    Oliver, J.2    McMenamin, P.G.3    Holt, P.G.4
  • 25
    • 0025845772 scopus 로고
    • Immunoregulation of asthma: Control of T-lymphocyte in the respiratory tract
    • Holt PG, McMenamin C, Schon-Hegrad MA et al. Immunoregulation of asthma: control of T-lymphocyte activation in the respiratory tract. Eur. Respir. J. 1991; 13 (Suppl.): S6-15.
    • (1991) Eur. Respir. J. , vol.13 , Issue.SUPPL.
    • Holt, P.G.1    McMenamin, C.2    Schon-Hegrad, M.A.3
  • 28
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 29
    • 0032161459 scopus 로고    scopus 로고
    • Airway epithelial integrins: Why so many?
    • Sheppard D. Airway epithelial integrins: why so many? Am. J. Respir. Cell. Mol. Biol. 1998; 19: 349-51.
    • (1998) Am. J. Respir. Cell. Mol. Biol. , vol.19 , pp. 349-351
    • Sheppard, D.1
  • 30
    • 0030219971 scopus 로고    scopus 로고
    • Epithelial integrins
    • Sheppard D. Epithelial integrins. Bioessays 1996; 18: 655-60.
    • (1996) Bioessays , vol.18 , pp. 655-660
    • Sheppard, D.1
  • 32
    • 0030777721 scopus 로고    scopus 로고
    • Beta 2 (CD18) and beta 1 (CD29) integrin mechanisms in migration of human polymorphonuclear leucocytes and monocytes through lung fibroblast barriers: Shared and distinct mechanisms
    • Shang XZ, Issekutz AC. Beta 2 (CD18) and beta 1 (CD29) integrin mechanisms in migration of human polymorphonuclear leucocytes and monocytes through lung fibroblast barriers: shared and distinct mechanisms. Immunology 1997; 92: 527-35.
    • (1997) Immunology , vol.92 , pp. 527-535
    • Shang, X.Z.1    Issekutz, A.C.2
  • 33
    • 0033870609 scopus 로고    scopus 로고
    • HGF/scatter factor selectively promotes cell invasion by increasing integrin avidity
    • Trusolino L, Cavassa S, Angelini P et al. HGF/scatter factor selectively promotes cell invasion by increasing integrin avidity. FASEBJ. 2000; 14: 1629-40.
    • (2000) FASEB J. , vol.14 , pp. 1629-1640
    • Trusolino, L.1    Cavassa, S.2    Angelini, P.3
  • 34
    • 0030023905 scopus 로고    scopus 로고
    • Extracellular matrix alters PDGF regulation of fibroblast integrins
    • Xu J, Clark RA. Extracellular matrix alters PDGF regulation of fibroblast integrins. J. Cell Biol. 1996; 132: 239-49.
    • (1996) J. Cell Biol. , vol.132 , pp. 239-249
    • Xu, J.1    Clark, R.A.2
  • 35
    • 0032586285 scopus 로고    scopus 로고
    • Alphavbeta3 and vitronectin expression by normal ovarian surface epithelial cells. Role in cell adhesion and cell proliferation
    • Cruet S, Salamanca C, Mitchell GW, Auersperg N. Alphavbeta3 and vitronectin expression by normal ovarian surface epithelial cells. Role in cell adhesion and cell proliferation. Gynecol. Oncol. 1999; 75: 254-60.
    • (1999) Gynecol. Oncol. , vol.75 , pp. 254-260
    • Cruet, S.1    Salamanca, C.2    Mitchell, G.W.3    Auersperg, N.4
  • 36
    • 0033227819 scopus 로고    scopus 로고
    • Alpha9beta1 integrin is expressed on human neutrophils and contributes to neutrophil migration through human lung and synovial fibroblast barriers
    • Shang T, Yednock T, Issekutz AC. Alpha9beta1 integrin is expressed on human neutrophils and contributes to neutrophil migration through human lung and synovial fibroblast barriers. J. Leukoc. Biol. 1999; 66: 809-16.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 809-816
    • Shang, T.1    Yednock, T.2    Issekutz, A.C.3
  • 37
    • 0028972023 scopus 로고
    • Role of the alpha 1 beta 1 integrin complex in collagen gel contraction in vitro by fibroblasts
    • Carver W, Molano I, Reaves TA, Borg TK, Terracio L. Role of the alpha 1 beta 1 integrin complex in collagen gel contraction in vitro by fibroblasts. J. Cell. Physiol. 1995; 165: 425-37.
    • (1995) J. Cell. Physiol. , vol.165 , pp. 425-437
    • Carver, W.1    Molano, I.2    Reaves, T.A.3    Borg, T.K.4    Terracio, L.5
  • 38
    • 0029796370 scopus 로고    scopus 로고
    • Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains
    • Yokosaki Y, Monis H, Chen J, Sheppard D. Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains. J. Biol. Chem. 1996; 271: 24144-50.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24144-24150
    • Yokosaki, Y.1    Monis, H.2    Chen, J.3    Sheppard, D.4
  • 39
    • 0033083972 scopus 로고    scopus 로고
    • Integrin engagement regulates proliferation and collagenase expression of rheumatoid synovial fibroblasts
    • Sarkissian M, Lafyatis R. Integrin engagement regulates proliferation and collagenase expression of rheumatoid synovial fibroblasts. J. Immunol. 1999; 162: 1772-9.
    • (1999) J. Immunol. , vol.162 , pp. 1772-1779
    • Sarkissian, M.1    Lafyatis, R.2
  • 40
    • 0033137070 scopus 로고    scopus 로고
    • Extracellular matrix and integrin signalling: The shape of things to come
    • Boudreau NJ, Jones PL. Extracellular matrix and integrin signalling: the shape of things to come. Biochem. J. 1999; 339: 1481-8.
    • (1999) Biochem. J. , vol.339 , pp. 1481-1488
    • Boudreau, N.J.1    Jones, P.L.2
  • 41
    • 0026645172 scopus 로고
    • Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis
    • Hertle MD, Kubler MD, Leigh IM, Watt FM. Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J. Clin. Invest. 1992; 89: 1892-901.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1892-1901
    • Hertle, M.D.1    Kubler, M.D.2    Leigh, I.M.3    Watt, F.M.4
  • 42
    • 0031782144 scopus 로고    scopus 로고
    • Vitronectin regulates smooth muscle contractility via alphav and beta1 integrin
    • Dahm LM, Bowers CW. Vitronectin regulates smooth muscle contractility via alphav and beta1 integrin. J. Cell Sci. 1998; 111: 1175-83.
    • (1998) J. Cell Sci. , vol.111 , pp. 1175-1183
    • Dahm, L.M.1    Bowers, C.W.2
  • 43
    • 0034763207 scopus 로고    scopus 로고
    • Regulation of human lung fibroblast phenotype and function by vitronectin and vitronectin integrins
    • Scaffidi AK, Moodley YP, Weichselbaum M, Thompson PJ, Knight DA. Regulation of human lung fibroblast phenotype and function by vitronectin and vitronectin integrins. J. Cell Sci. 2001; 114: 3507-16.
    • (2001) J. Cell Sci. , vol.114 , pp. 3507-3516
    • Scaffidi, A.K.1    Moodley, Y.P.2    Weichselbaum, M.3    Thompson, P.J.4    Knight, D.A.5
  • 44
    • 15844420283 scopus 로고    scopus 로고
    • Localisation of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
    • Brooks PC, Stromblad S, Sanders LC et al. Localisation of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996; 85: 683-93.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3
  • 45
    • 0028987190 scopus 로고
    • Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin
    • Huhtala P, Humphries MJ, McCarthy JB, Tremble PM, Werb Z, Damsky CH. Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J. Cell Biol. 1995; 129: 867-79
    • (1995) J. Cell Biol. , vol.129 , pp. 867-879
    • Huhtala, P.1    Humphries, M.J.2    McCarthy, J.B.3    Tremble, P.M.4    Werb, Z.5    Damsky, C.H.6
  • 46
    • 0030860609 scopus 로고    scopus 로고
    • Regulation of tenascin-c, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth
    • Jones PL, Crack J, Rabinovitch M. Regulation of tenascin-c, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J. Cell Biol. 1997; 139: 279-93.
    • (1997) J. Cell Biol. , vol.139 , pp. 279-293
    • Jones, P.L.1    Crack, J.2    Rabinovitch, M.3
  • 47
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger JS, Huang X, Kawakatsu H et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999; 96: 319-28.
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.S.1    Huang, X.2    Kawakatsu, H.3
  • 48
    • 0029965462 scopus 로고    scopus 로고
    • Transient functional expression of alphaVbeta 3 on vascular cells during wound repair
    • Clark RA, Tonnesen MG, Gailit J, Cheresh DA. Transient functional expression of alphaVbeta 3 on vascular cells during wound repair. Am. J. Pathol. 1996; 148: 1407-21.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1407-1421
    • Clark, R.A.1    Tonnesen, M.G.2    Gailit, J.3    Cheresh, D.A.4
  • 49
  • 50
  • 51
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M et al. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994; 79: 1157-64.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3
  • 52
    • 0034670372 scopus 로고    scopus 로고
    • A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth
    • Cambier S, Mu DZ, O'Connell D et al. A role for the integrin alphavbeta8 in the negative regulation of epithelial cell growth. Cancer Res. 2000; 60: 7084-93.
    • (2000) Cancer Res. , vol.60 , pp. 7084-7093
    • Cambier, S.1    Mu, D.Z.2    O'Connell, D.3
  • 53
    • 0026769303 scopus 로고
    • The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects
    • Montefort S, Roberts JA, Beasley R, Holgate ST, Roche WR. The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects. Thorax 1992; 47: 499-503.
    • (1992) Thorax , vol.47 , pp. 499-503
    • Montefort, S.1    Roberts, J.A.2    Beasley, R.3    Holgate, S.T.4    Roche, W.R.5
  • 54
    • 0027467738 scopus 로고
    • Ciliated cell damage in the bronchial epithelium of asthmatics and non-asthmatics
    • Montefort S, Djukanovic R, Holgate ST, Roche WR. Ciliated cell damage in the bronchial epithelium of asthmatics and non-asthmatics. Clin. Exp. Allergy 1993; 23: 185-9.
    • (1993) Clin. Exp. Allergy , vol.23 , pp. 185-189
    • Montefort, S.1    Djukanovic, R.2    Holgate, S.T.3    Roche, W.R.4
  • 55
    • 0034080463 scopus 로고    scopus 로고
    • Epithelial damage and response
    • Holgate ST. Epithelial damage and response. Clin. Exp. Allergy 2000; 30 (Suppl. 1): 37-41.
    • (2000) Clin. Exp. Allergy , vol.30 , Issue.SUPPL. 1 , pp. 37-41
    • Holgate, S.T.1
  • 56
    • 0037113883 scopus 로고    scopus 로고
    • Proteinase-mediated release of epithelial cell-associated CD44. Extracellular CD44 complexes with components of cellular matrices
    • Cichy J, Bals R, Potempa J, Mani A, Pure E. Proteinase-mediated release of epithelial cell-associated CD44. Extracellular CD44 complexes with components of cellular matrices. J. Biol. Chem. 2002; 277: 44440-7.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44440-44447
    • Cichy, J.1    Bals, R.2    Potempa, J.3    Mani, A.4    Pure, E.5
  • 57
  • 58
    • 0019164990 scopus 로고
    • Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen
    • Terranova VP, Rohrbach DH, Martin GR. Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen. Cell 1980; 22: 719-26.
    • (1980) Cell , vol.22 , pp. 719-726
    • Terranova, V.P.1    Rohrbach, D.H.2    Martin, G.R.3
  • 59
    • 0029916820 scopus 로고    scopus 로고
    • Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle
    • Boudreau N, Werb Z, Bissell MJ. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc. Natl Acad. Sci. USA 1996; 93: 3509-13.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3509-3513
    • Boudreau, N.1    Werb, Z.2    Bissell, M.J.3
  • 60
    • 0026542959 scopus 로고
    • Basement membrane proteins: Structure, assembly, and cellular interactions
    • Paulsson M. Basement membrane proteins: structure, assembly, and cellular interactions. Crit. Rev. Biochem. Mol. Biol. 1992; 27: 93-127.
    • (1992) Crit. Rev. Biochem. Mol. Biol. , vol.27 , pp. 93-127
    • Paulsson, M.1
  • 61
    • 0036444252 scopus 로고    scopus 로고
    • Distribution of basement membrane pores in bronchus revealed by microscopy following epithelial removal
    • Howat WJ, Barabas T, Holmes JA, Holgate ST, Lackie PM. Distribution of basement membrane pores in bronchus revealed by microscopy following epithelial removal. J. Struct. Biol. 2002; 139: 137-45.
    • (2002) J. Struct. Biol. , vol.139 , pp. 137-145
    • Howat, W.J.1    Barabas, T.2    Holmes, J.A.3    Holgate, S.T.4    Lackie, P.M.5
  • 62
    • 0035135666 scopus 로고    scopus 로고
    • Basement membrane pores in human bronchial epithelium: A conduct for infiltrating cells?
    • Howat WJ, Holmes JA, Holgate ST, Lackie PM. Basement membrane pores in human bronchial epithelium: a conduct for infiltrating cells? Am. J. Pathol. 2001; 158: 673-80.
    • (2001) Am. J. Pathol. , vol.158 , pp. 673-680
    • Howat, W.J.1    Holmes, J.A.2    Holgate, S.T.3    Lackie, P.M.4
  • 63
    • 0035070142 scopus 로고    scopus 로고
    • Epithelium-fibroblast interactions in response to airway inflammation
    • Knight D. Epithelium-fibroblast interactions in response to airway inflammation. Immunol. Cell Biol. 2001; 79: 160-4.
    • (2001) Immunol. Cell Biol. , vol.79 , pp. 160-164
    • Knight, D.1
  • 64
    • 0031765612 scopus 로고    scopus 로고
    • The inflammation-repair cycle in asthma: The pivotal role of the airway epithelium
    • Holgate ST. The inflammation-repair cycle in asthma: the pivotal role of the airway epithelium. Clin. Exp. Allergy 1998; 28: 97-103.
    • (1998) Clin. Exp. Allergy , vol.28 , pp. 97-103
    • Holgate, S.T.1
  • 65
    • 0033826756 scopus 로고    scopus 로고
    • Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma
    • Holgate ST, Lackie P, Wilson S, Roche W, Davies D. Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. Am. J. Respir. Crit. Care Med. 2000; 162: S113-17.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.162
    • Holgate, S.T.1    Lackie, P.2    Wilson, S.3    Roche, W.4    Davies, D.5
  • 66
    • 0029908521 scopus 로고    scopus 로고
    • The uptake of mineral particles by pulmonary epithelial cells
    • Churg A. The uptake of mineral particles by pulmonary epithelial cells. Am. J. Respir. Crit. Care Med. 1996; 154: 1124-40.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 1124-1140
    • Churg, A.1
  • 69
    • 0032777880 scopus 로고    scopus 로고
    • Cytokines in asthma
    • Chung KF, Barnes PJ. Cytokines in asthma. Thorax 1999; 54: 825-57.
    • (1999) Thorax , vol.54 , pp. 825-857
    • Chung, K.F.1    Barnes, P.J.2
  • 70
    • 0028587555 scopus 로고
    • Proinflammatory potential of the airway epithelium in bronchial asthma
    • Raeburn D, Webber SE. Proinflammatory potential of the airway epithelium in bronchial asthma. Eur. Respir. J. 1994; 7: 2226-33.
    • (1994) Eur. Respir. J. , vol.7 , pp. 2226-2233
    • Raeburn, D.1    Webber, S.E.2
  • 71
    • 0026511180 scopus 로고
    • Arachidonic acid metabolism in airway epithelial cells
    • Holtzman MJ. Arachidonic acid metabolism in airway epithelial cells. Annu. Rev. Physiol. 1992; 54: 303-29.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 303-329
    • Holtzman, M.J.1
  • 72
    • 0028985418 scopus 로고
    • 2 but not prostacyclin inhibits histamine-induced contraction of human bronchial smooth muscle
    • 2 but not prostacyclin inhibits histamine-induced contraction of human bronchial smooth muscle. Eur. J. Pharmacol. 1995; 272: 13-19.
    • (1995) Eur. J. Pharmacol. , vol.272 , pp. 13-19
    • Knight, D.A.1    Stewart, G.A.2    Thompson, P.J.3
  • 73
    • 0028921510 scopus 로고
    • Epithelium-derived inhibitory prostaglandins modulate human bronchial smooth muscle responses to histamine
    • Knight DA, Stewart GA, Lai ML, Thompson PJ. Epithelium-derived inhibitory prostaglandins modulate human bronchial smooth muscle responses to histamine. Eur. J. Pharmacol. 1995; 272: 1-11.
    • (1995) Eur. J. Pharmacol. , vol.272 , pp. 1-11
    • Knight, D.A.1    Stewart, G.A.2    Lai, M.L.3    Thompson, P.J.4
  • 74
    • 0028911427 scopus 로고
    • Bronchoprotective role for endogenous prostaglandin E2
    • Pavord ID, Tattersfield AE. Bronchoprotective role for endogenous prostaglandin E2 [see comments]. Lancet 1995; 345: 436-8.
    • (1995) Lancet , vol.345 , pp. 436-438
    • Pavord, I.D.1    Tattersfield, A.E.2
  • 75
    • 0030003302 scopus 로고    scopus 로고
    • Cultured epithelial cells release cyclooxygenase-dependent and cyclooxygenase-independent factors that inhibit cholinergic contraction of canine airway smooth muscles
    • Matsumoto K, Aizawa H, Takata S, Koto H, Inoue H, Hara N. Cultured epithelial cells release cyclooxygenase-dependent and cyclooxygenase-independent factors that inhibit cholinergic contraction of canine airway smooth muscles. Respiration 1996; 63: 205-12.
    • (1996) Respiration , vol.63 , pp. 205-212
    • Matsumoto, K.1    Aizawa, H.2    Takata, S.3    Koto, H.4    Inoue, H.5    Hara, N.6
  • 76
    • 0031179646 scopus 로고    scopus 로고
    • IL-12 deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kalinski P, Hilkens CMU, Snijders A, Snijdewint FGM, Kapsenberg ML. IL-12 deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J. Immunol. 1997; 159: 28-35.
    • (1997) J. Immunol. , vol.159 , pp. 28-35
    • Kalinski, P.1    Hilkens, C.M.U.2    Snijders, A.3    Snijdewint, F.G.M.4    Kapsenberg, M.L.5
  • 78
    • 0026623555 scopus 로고
    • Cloning of human airway 15-lipoxygenase: Identity to the reticulocyte enzyme and expression in epithelium
    • Sigal E, Dicharry S, Highland E, Finkbeiner WE. Cloning of human airway 15-lipoxygenase: identity to the reticulocyte enzyme and expression in epithelium. Am. J. Physiol. 1992; 262: L392-8.
    • (1992) Am. J. Physiol. , vol.262
    • Sigal, E.1    Dicharry, S.2    Highland, E.3    Finkbeiner, W.E.4
  • 80
    • 0022997831 scopus 로고
    • Arachidonic acid metabolism by canine tracheal epithelial cells. Product formation and relationship to chloride secretion
    • Eling TE, Danilowicz RM, Henke DC, Sivarajah K, Yankaskas JR, Boucher RC. Arachidonic acid metabolism by canine tracheal epithelial cells. Product formation and relationship to chloride secretion. J. Biol. Chem. 1986; 261: 12841-9.
    • (1986) J. Biol. Chem. , vol.261 , pp. 12841-12849
    • Eling, T.E.1    Danilowicz, R.M.2    Henke, D.C.3    Sivarajah, K.4    Yankaskas, J.R.5    Boucher, R.C.6
  • 81
    • 0022372510 scopus 로고
    • Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea
    • Hunter JA, Finkbeiner WE, Nadel JA, Goetzl EJ, Holtzman MJ. Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc. Natl Acad. Sci. USA 1985; 82: 4633-7.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 4633-4637
    • Hunter, J.A.1    Finkbeiner, W.E.2    Nadel, J.A.3    Goetzl, E.J.4    Holtzman, M.J.5
  • 82
    • 0032065589 scopus 로고    scopus 로고
    • Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells
    • Hill EM, Eling T, Nettesheim P. Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 1998; 18: 662-9.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.18 , pp. 662-669
    • Hill, E.M.1    Eling, T.2    Nettesheim, P.3
  • 83
    • 0034063822 scopus 로고    scopus 로고
    • Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients
    • Kowalski ML, Pawliczak R, Wozniak J et al. Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. Am. J. Respir. Crit. Care Med. 2000; 161: 391-8.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 391-398
    • Kowalski, M.L.1    Pawliczak, R.2    Wozniak, J.3
  • 84
    • 0028701350 scopus 로고
    • Leukotrienes mediate delayed airway effects of 15-HETE
    • Schellenberg RR, Tsang S, Salari H. Leukotrienes mediate delayed airway effects of 15-HETE. Ann. NY. Acad. Sci. 1994; 744: 243-50.
    • (1994) Ann. NY. Acad. Sci. , vol.744 , pp. 243-250
    • Schellenberg, R.R.1    Tsang, S.2    Salari, H.3
  • 85
    • 0027231012 scopus 로고
    • Respiratory epithelium modulates the responses of canine bronchi to cooling
    • Gao Y, Vanhoutte PM. Respiratory epithelium modulates the responses of canine bronchi to cooling. J. Appl. Physiol. 1993; 74: 2421-5.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 2421-2425
    • Gao, Y.1    Vanhoutte, P.M.2
  • 88
    • 0030711558 scopus 로고    scopus 로고
    • Nitric oxide synthases. Which, where, how and why?
    • Michel T, Feron O. Nitric oxide synthases. Which, where, how and why? J. Clin. Invest. 1997; 100: 2146-52.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2146-2152
    • Michel, T.1    Feron, O.2
  • 90
    • 0029050604 scopus 로고
    • Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide
    • Kharitonov SA, O'Connor BJ, Evans DJ, Barnes PJ. Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am. J. Respir. Crit. Care Med. 1995; 151: 1894-9.
    • (1995) Am. J. Respir. Crit. Care Med. , vol.151 , pp. 1894-1899
    • Kharitonov, S.A.1    O'Connor, B.J.2    Evans, D.J.3    Barnes, P.J.4
  • 91
    • 0027427353 scopus 로고
    • Increased amount of nitric oxide in exhaled air of asthmatics
    • Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur. Respir. J. 1993; 6: 1368-70.
    • (1993) Eur. Respir. J. , vol.6 , pp. 1368-1370
    • Alving, K.1    Weitzberg, E.2    Lundberg, J.M.3
  • 92
    • 0000564518 scopus 로고    scopus 로고
    • Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma
    • Ricciardolo FL, Geppetti P, Mistretta A et al. Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma. Lancet 1996; 348: 374-7.
    • (1996) Lancet , vol.348 , pp. 374-377
    • Ricciardolo, F.L.1    Geppetti, P.2    Mistretta, A.3
  • 93
    • 0033020245 scopus 로고    scopus 로고
    • Epidermal growth factor system regulates mucin production in airways
    • Takeyama K, Dabbagh K, Lee HM et al. Epidermal growth factor system regulates mucin production in airways. Proc. Natl Acad. Sci. USA 1999; 96: 3081-6.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3081-3086
    • Takeyama, K.1    Dabbagh, K.2    Lee, H.M.3
  • 94
    • 0035933795 scopus 로고    scopus 로고
    • Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors
    • Sweeney C, Fambrough D, Huard C et al. Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors. J. Biol. Chem. 2001; 276: 22 685-98.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22685-22698
    • Sweeney, C.1    Fambrough, D.2    Huard, C.3
  • 95
    • 0031808337 scopus 로고    scopus 로고
    • Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway
    • Amishima M, Munakata M, Nasuhara Y et al. Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway. Am. J. Respir. Crit. Care Med. 1998; 157: 1907-12.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 1907-1912
    • Amishima, M.1    Munakata, M.2    Nasuhara, Y.3
  • 96
    • 0033923224 scopus 로고    scopus 로고
    • Involvement of the epidermal growth factor receptor in epithelial repair in asthma
    • Puddicombe SM, Polosa R, Richter A et al. Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEBJ. 2000; 14: 1362-74.
    • (2000) FASEB J. , vol.14 , pp. 1362-1374
    • Puddicombe, S.M.1    Polosa, R.2    Richter, A.3
  • 98
    • 0033214444 scopus 로고    scopus 로고
    • The EGF receptor as central transducer of heterologous signalling systems
    • Zwick E, Hackel PO, Prenzel N, Ullrich A. The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol. Sci. 1999; 20: 408-12.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 408-412
    • Zwick, E.1    Hackel, P.O.2    Prenzel, N.3    Ullrich, A.4
  • 99
    • 0032915392 scopus 로고    scopus 로고
    • Epidermal growth factor receptors: Critical mediators of multiple receptor pathways
    • Hackel PO, Zwick E, Prenzel N, Ullrich A. Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr. Opin. Cell Biol. 1999; 11: 184-9.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 184-189
    • Hackel, P.O.1    Zwick, E.2    Prenzel, N.3    Ullrich, A.4
  • 100
    • 0035933814 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) receptor dependent ERK activation by G protein-coupled receptors: A co-culture system for identifying intermediates upstream and downstream of heparin-binding-EGF shedding
    • Pierce KL, Tohgo A, Ahn S, Field ME, Luttrell LM, Lefkowitz RJ. Epidermal growth factor (EGF) receptor dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding-EGF shedding. J. Biol. Chem. 2001; 276: 23 155-60.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23155-23160
    • Pierce, K.L.1    Tohgo, A.2    Ahn, S.3    Field, M.E.4    Luttrell, L.M.5    Lefkowitz, R.J.6
  • 101
    • 0034855942 scopus 로고    scopus 로고
    • Nuclear localization of EGF receptor and its potential new role as a transcription factor
    • Lin SY, Makino K, Xia W et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell Biol. 2001; 3: 802-8.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 802-808
    • Lin, S.Y.1    Makino, K.2    Xia, W.3
  • 102
    • 0035009330 scopus 로고    scopus 로고
    • IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils
    • Shim JJ, Dabbagh K, Ueki IF et al. IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001; 280: L134-40.
    • (2001) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.280
    • Shim, J.J.1    Dabbagh, K.2    Ueki, I.F.3
  • 103
    • 0035253672 scopus 로고    scopus 로고
    • Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1phase cell-cycle progression
    • Assoian RK, Schwartz MA. Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1phase cell-cycle progression. Curr. Opin. Genet. Dev. 2001; 11: 48-53.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 48-53
    • Assoian, R.K.1    Schwartz, M.A.2
  • 104
    • 0033001953 scopus 로고    scopus 로고
    • Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes
    • Fambrough D, McClure K, Kazlauskas A, Lander ES. Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. Cell 1999; 97: 727-41.
    • (1999) Cell , vol.97 , pp. 727-741
    • Fambrough, D.1    McClure, K.2    Kazlauskas, A.3    Lander, E.S.4
  • 105
    • 0033838960 scopus 로고    scopus 로고
    • Synergistic stimulation of airway smooth muscle cell mitogenesis
    • Ediger TL, Toews ML. Synergistic stimulation of airway smooth muscle cell mitogenesis. J. Pharmacol. Exp. Ther. 2000; 294: 1076-82.
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 1076-1082
    • Ediger, T.L.1    Toews, M.L.2
  • 107
    • 0032927810 scopus 로고    scopus 로고
    • Suppression of transforming growth factor-beta isoforms, TGF-beta receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix
    • Tseng SC, Li DQ, Ma X. Suppression of transforming growth factor-beta isoforms, TGF-beta receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix. J. Cell. Physiol. 1999; 179: 325-35.
    • (1999) J. Cell. Physiol. , vol.179 , pp. 325-335
    • Tseng, S.C.1    Li, D.Q.2    Ma, X.3
  • 108
  • 109
    • 0034994719 scopus 로고    scopus 로고
    • TGF-{beta} receptor types I and II are differentially expressed during corneal epithelial wound repair
    • Zieske ID, Hutcheon AEK, Guo X, Chung E-H, Joyce NC. TGF-{beta} receptor types I and II are differentially expressed during corneal epithelial wound repair. Invest. Ophthalmol. Vis. Sci. 2001; 42: 1465-71.
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 1465-1471
    • Zieske, I.D.1    Hutcheon, A.E.K.2    Guo, X.3    Chung, E.-H.4    Joyce, N.C.5
  • 110
  • 111
    • 0037099745 scopus 로고    scopus 로고
    • TGF-{beta} receptor-activated p38 MAP kinase mediates Smad-independent TGF-{beta} responses
    • Yu L, Hebert MC, Zhang YE. TGF-{beta} receptor-activated p38 MAP kinase mediates Smad-independent TGF-{beta} responses. EMBOJ. 2002; 21: 3749-59.
    • (2002) EMBO J. , vol.21 , pp. 3749-3759
    • Yu, L.1    Hebert, M.C.2    Zhang, Y.E.3
  • 112
    • 0029841299 scopus 로고    scopus 로고
    • TGF beta 1 promotes actin cytoskeleton reorganization and migratory phenotype in epithelial tracheal cells in primary culture
    • Boland S, Boisvieux-Ulrich E, Houcine O etal. TGF beta 1 promotes actin cytoskeleton reorganization and migratory phenotype in epithelial tracheal cells in primary culture. J. Cell Sci. 1996; 109: 2207-19.
    • (1996) J. Cell Sci. , vol.109 , pp. 2207-2219
    • Boland, S.1    Boisvieux-Ulrich, E.2    Houcine, O.3
  • 113
  • 114
    • 0025760355 scopus 로고
    • Roles of neutral endopeptidase in airways
    • Borson DB. Roles of neutral endopeptidase in airways. Am. J. Physiol. 1991; 260: L212-25.
    • (1991) Am. J. Physiol. , vol.260
    • Borson, D.B.1
  • 115
    • 0026093160 scopus 로고
    • Modulation of neurogenic inflammation by neutral endopeptidase
    • Nadel JA, Borson DB. Modulation of neurogenic inflammation by neutral endopeptidase. Am. Rev. Respir. Dis. 1991; 143: S33-6.
    • (1991) Am. Rev. Respir. Dis. , vol.143
    • Nadel, J.A.1    Borson, D.B.2
  • 116
    • 0026707629 scopus 로고
    • Role of acetylcholinesterase in airway epithelium-mediated inhibition of acetylcholine-induced contraction of guinea-pig isolated trachea
    • Koga Y, Satoh S, Sodeyama N, Hashimoto Y, Yanagisawa T. Hirshman CA. Role of acetylcholinesterase in airway epithelium-mediated inhibition of acetylcholine-induced contraction of guinea-pig isolated trachea. Eur. J. Pharmacol. 1992; 220: 141-6.
    • (1992) Eur. J. Pharmacol. , vol.220 , pp. 141-146
    • Koga, Y.1    Satoh, S.2    Sodeyama, N.3    Hashimoto, Y.4    Yanagisawa, T.5    Hirshman, C.A.6
  • 117
    • 0026766944 scopus 로고
    • Histamine N-methyltransferase controls the contractile response of guinea pig trachea to histamine
    • Ohrui T, Yamauchi K, Sekizawa K et al. Histamine N-methyltransferase controls the contractile response of guinea pig trachea to histamine. J. Pharmacol. Exp. Ther. 1992; 261: 1268-72.
    • (1992) J. Pharmacol. Exp. Ther. , vol.261 , pp. 1268-1272
    • Ohrui, T.1    Yamauchi, K.2    Sekizawa, K.3
  • 118
    • 0030778321 scopus 로고    scopus 로고
    • Airway epithelial repair: Breath-takingly quick and multipotentially pathogenic
    • Erjefalt JS, Persson CG. Airway epithelial repair: breath-takingly quick and multipotentially pathogenic. Thorax 1997; 52: 1010-2
    • (1997) Thorax , vol.52 , pp. 1010-1012
    • Erjefalt, J.S.1    Persson, C.G.2
  • 120
    • 0030718616 scopus 로고    scopus 로고
    • Association between inflammation and epithelial damage-restitution processes in allergic airways in vivo
    • Erjefalt JS, Korsgren M, Nilsson MC, Sundley F, Persson CGA. Association between inflammation and epithelial damage-restitution processes in allergic airways in vivo. Clin. Exp. Allergy 1997; 27: 1344-55.
    • (1997) Clin. Exp. Allergy , vol.27 , pp. 1344-1355
    • Erjefalt, J.S.1    Korsgren, M.2    Nilsson, M.C.3    Sundley, F.4    Persson, C.G.A.5
  • 121
    • 0027970169 scopus 로고
    • Microcirculation-derived factors in airway epithelial repair in vivo
    • Erjefalt JS, Erjefalt I, Sundler F, Persson CG. Microcirculation-derived factors in airway epithelial repair in vivo. Microvasc. Res. 1994; 48: 161-78.
    • (1994) Microvasc. Res. , vol.48 , pp. 161-178
    • Erjefalt, J.S.1    Erjefalt, I.2    Sundler, F.3    Persson, C.G.4
  • 122
    • 0029942269 scopus 로고    scopus 로고
    • Epithelial cells, barrier functions and shedding-restitution mechanisms
    • Persson CG. Epithelial cells, barrier functions and shedding-restitution mechanisms. Am. J. Respir. Crit. Care Med. 1996; 153: S9-10.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153
    • Persson, C.G.1
  • 123
    • 0028580436 scopus 로고
    • Synchronous appearance of fibronectin, integrin alpha 5 beta 1, vinculin and actin in epithelial cells and fibroblasts during rat tracheal wound healing
    • Horiba K, Fukuda Y. Synchronous appearance of fibronectin, integrin alpha 5 beta 1, vinculin and actin in epithelial cells and fibroblasts during rat tracheal wound healing. Virchows Arch. 1994; 425: 425-34.
    • (1994) Virchows Arch. , vol.425 , pp. 425-434
    • Horiba, K.1    Fukuda, Y.2
  • 125
    • 0026165309 scopus 로고
    • Attachment characteristics of bovine bronchial epithelial cells to extracellular matrix components
    • Rickard KA, Shoji S, Spurzem JR, Rennard SI. Attachment characteristics of bovine bronchial epithelial cells to extracellular matrix components. Am. J. Respir. Cell Mol. Biol. 1991; 4: 440-8.
    • (1991) Am. J. Respir. Cell Mol. Biol. , vol.4 , pp. 440-448
    • Rickard, K.A.1    Shoji, S.2    Spurzem, J.R.3    Rennard, S.I.4
  • 126
    • 0030694885 scopus 로고    scopus 로고
    • Selective migration of alpha-smooth muscle actin-positive myofibroblasts toward fibronectin in the Boyden's blindwell chamber
    • Kawamoto M, Matsunami T, Ertl RF et al. Selective migration of alpha-smooth muscle actin-positive myofibroblasts toward fibronectin in the Boyden's blindwell chamber. Clin. Sci. (Lond). 1997; 93: 355-62.
    • (1997) Clin. Sci. (Lond.) , vol.93 , pp. 355-362
    • Kawamoto, M.1    Matsunami, T.2    Ertl, R.F.3
  • 128
    • 0033950912 scopus 로고    scopus 로고
    • Differentiated and functional human airway epithelium regeneration in tracheal xenografts
    • Dupuit F, Gaillard D, Hinnrasky J et al. Differentiated and functional human airway epithelium regeneration in tracheal xenografts. Am. J. Physiol. Lung Cell. Mol. Physiol. 2000; 278: L165-L176.
    • (2000) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.278
    • Dupuit, F.1    Gaillard, D.2    Hinnrasky, J.3
  • 129
    • 0030949875 scopus 로고    scopus 로고
    • Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman MJ, Anderson GM, Stolzenberg ED, Kari UP, Zasloff M, Wilson JM. Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 1997; 88: 553-60.
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.J.1    Anderson, G.M.2    Stolzenberg, E.D.3    Kari, U.P.4    Zasloff, M.5    Wilson, J.M.6
  • 130
    • 0028804840 scopus 로고
    • Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis
    • Zhang Y, Doranz B, Yankaskas JR, Engelhardt JF. Genotypic analysis of respiratory mucous sulfation defects in cystic fibrosis. J. Clin. Invest. 1995; 96: 2997-3004.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2997-3004
    • Zhang, Y.1    Doranz, B.2    Yankaskas, J.R.3    Engelhardt, J.F.4
  • 131
    • 0028981979 scopus 로고
    • Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway
    • Goldman MJ, Wilson JM. Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway. J. Virol. 1995; 69: 5951-8.
    • (1995) J. Virol. , vol.69 , pp. 5951-5958
    • Goldman, M.J.1    Wilson, J.M.2
  • 132
    • 0029091783 scopus 로고
    • Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: A preclinical toxicology study
    • Goldman MJ, Litzky LA, Engelhardt JF, Wilson JM. Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study. Hum. Gene Ther. 1995; 6: 839-51.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 839-851
    • Goldman, M.J.1    Litzky, L.A.2    Engelhardt, J.F.3    Wilson, J.M.4
  • 133
    • 0031957991 scopus 로고    scopus 로고
    • Expression of growth factors and remodelling of the airway wall in bronchial asthma
    • Hoshino M, Nakamura Y, Sim JJ. Expression of growth factors and remodelling of the airway wall in bronchial asthma. Thorax 1998; 53: 21-7.
    • (1998) Thorax , vol.53 , pp. 21-27
    • Hoshino, M.1    Nakamura, Y.2    Sim, J.J.3
  • 134
    • 0032903716 scopus 로고    scopus 로고
    • Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: A in vitro co-culture model of airway remodeling in asthma
    • Zhang S, Smartt H, Holgate ST, Roche WR. Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma. Lab. Invest. 1999; 79: 395-405.
    • (1999) Lab. Invest. , vol.79 , pp. 395-405
    • Zhang, S.1    Smartt, H.2    Holgate, S.T.3    Roche, W.R.4
  • 135
    • 0028122690 scopus 로고
    • Heterogeneity of myofibroblast phenotypic features: An example of fibroblastic cell plasticity
    • Schmitt-Graff A, Desmouliere A, Gabbiani G. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch. 1994; 425: 3-24.
    • (1994) Virchows Arch. , vol.425 , pp. 3-24
    • Schmitt-Graff, A.1    Desmouliere, A.2    Gabbiani, G.3
  • 138
    • 18544393745 scopus 로고    scopus 로고
    • Impaired lung branching morphogenesis in the absence of functional EGF receptor
    • Miettinen PJ, Warburton D, Bu D et al. Impaired lung branching morphogenesis in the absence of functional EGF receptor. Dev. Biol. 1997; 186: 224-36.
    • (1997) Dev. Biol. , vol.186 , pp. 224-236
    • Miettinen, P.J.1    Warburton, D.2    Bu, D.3
  • 139
    • 0028326107 scopus 로고
    • Epithelial-mesenchymal interactions in lung development
    • Minoo P, King RJ. Epithelial-mesenchymal interactions in lung development. Annu. Rev. Physiol. 1994; 56: 13-45.
    • (1994) Annu. Rev. Physiol. , vol.56 , pp. 13-45
    • Minoo, P.1    King, R.J.2
  • 140
    • 0031802178 scopus 로고    scopus 로고
    • The development of large and small airways
    • Jeffrey PK. The development of large and small airways. Am. J. Respir. Crit. Care Med. 1998; 157: S174-80.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157
    • Jeffrey, P.K.1
  • 142
    • 0036887572 scopus 로고    scopus 로고
    • Asthma: The importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma
    • Davies DE, Holgate ST. Asthma: the importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma. Int. J. Biochem. Cell Biol. 2002; 34: 1520-6.
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1520-1526
    • Davies, D.E.1    Holgate, S.T.2
  • 143
    • 0035049370 scopus 로고    scopus 로고
    • Invited lecture: Activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma
    • Holgate ST, Lackie PM, Howarth PH et al. Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma. Int. Arch. Allergy Immunol. 2001; 124: 253-8.
    • (2001) Int. Arch. Allergy Immunol. , vol.124 , pp. 253-258
    • Holgate, S.T.1    Lackie, P.M.2    Howarth, P.H.3
  • 146
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for non-hematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for non-hematopoietic tissues. Science 1997; 276: 71-4.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 147
    • 0029091682 scopus 로고
    • Identification and characterization of a fibroblast marker: FSP1
    • Strutz F, Okada H, Lo CW et al. Identification and characterization of a fibroblast marker: FSP1. J. Cell Biol. 1995; 130: 393-405.
    • (1995) J. Cell Biol. , vol.130 , pp. 393-405
    • Strutz, F.1    Okada, H.2    Lo, C.W.3
  • 148
    • 0035136844 scopus 로고    scopus 로고
    • TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2)
    • Strutz F, Zeisberg M, Renziehausen A et al. TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2). Kidney Int. 2001; 59: 579-92.
    • (2001) Kidney Int. , vol.59 , pp. 579-592
    • Strutz, F.1    Zeisberg, M.2    Renziehausen, A.3
  • 149
    • 0029112292 scopus 로고
    • The fibroblast - A (trans-)differentiated cell?
    • Strutz F. The fibroblast-a (trans-)differentiated cell? Nephrol. Dial. Transplant. 1995; 10: 1504-6.
    • (1995) Nephrol. Dial. Transplant. , vol.10 , pp. 1504-1506
    • Strutz, F.1
  • 151
    • 0032842887 scopus 로고    scopus 로고
    • Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro
    • Fan JM, Ng YY, Hill PA et al. Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int. 1999; 56: 1455-67.
    • (1999) Kidney Int. , vol.56 , pp. 1455-1467
    • Fan, J.M.1    Ng, Y.Y.2    Hill, P.A.3
  • 153
    • 0035891783 scopus 로고    scopus 로고
    • Remodeling of the airway epithelium in asthma
    • Fahy JV. Remodeling of the airway epithelium in asthma. Am. J. Respir. Crit. Care Med. 2001; 164: S46-51.
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164
    • Fahy, J.V.1
  • 155
    • 0033135134 scopus 로고    scopus 로고
    • Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma
    • Sampath D, Castro M, Look DC, Holtzman MI. Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J. Clin. Invest. 1999; 103: 1353-61.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1353-1361
    • Sampath, D.1    Castro, M.2    Look, D.C.3    Holtzman, M.I.4
  • 156
    • 0035190162 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium
    • Mullings RE, Wilson SJ, Puddicombe SM et al. Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium. J. Allergy Clin. Immunol. 2001; 108: 832-8.
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 832-838
    • Mullings, R.E.1    Wilson, S.J.2    Puddicombe, S.M.3
  • 157
    • 0037214465 scopus 로고    scopus 로고
    • Increased expression of p21 (waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium
    • Puddicombe SM, Torres-Lozano C, Richter A et al. Increased expression of p21 (waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium. Am. J. Respir. Cell. Mol. Biol. 2003; 28: 61-8.
    • (2003) Am. J. Respir. Cell. Mol. Biol. , vol.28 , pp. 61-68
    • Puddicombe, S.M.1    Torres-Lozano, C.2    Richter, A.3
  • 158
    • 0035184146 scopus 로고    scopus 로고
    • Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma
    • Knight D, Lim S, Scaffidi A et al. Protease-activated receptors in human airways: Upregulation of PAR-2 in respiratory epithelium from patients with asthma. J. Allergy Clin. Immunol. 2001; 108: 797-803.
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 797-803
    • Knight, D.1    Lim, S.2    Scaffidi, A.3
  • 159
    • 0033545627 scopus 로고    scopus 로고
    • A protective role for protease-activated receptors in the airways
    • Cocks TM, Fong B, Chow JM et al. A protective role for protease-activated receptors in the airways. Nature 1999; 398: 156-60.
    • (1999) Nature , vol.398 , pp. 156-160
    • Cocks, T.M.1    Fong, B.2    Chow, J.M.3
  • 160
    • 0034547916 scopus 로고    scopus 로고
    • Delayed onset of inflammation in protease-activated receptor-2-deficient mice
    • Lindner JR, Kahn ML, Coughlin SR et al. Delayed onset of inflammation in protease-activated receptor-2-deficient mice. J. Immunol. 2000; 165: 6504-10.
    • (2000) J. Immunol. , vol.165 , pp. 6504-6510
    • Lindner, J.R.1    Kahn, M.L.2    Coughlin, S.R.3
  • 161
    • 0033971235 scopus 로고    scopus 로고
    • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
    • Steinhoff M, Vergnolle N, Young SH et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nat. Med. 2000; 6: 151-8.
    • (2000) Nat. Med. , vol.6 , pp. 151-158
    • Steinhoff, M.1    Vergnolle, N.2    Young, S.H.3
  • 162
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR) -1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan N, Graham PT, Fink J et al. Activation of protease-activated receptor (PAR) -1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J. Immunol. 2002; 168: 3577-85.
    • (2002) J. Immunol. , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3
  • 163
    • 0031785140 scopus 로고    scopus 로고
    • Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients and the effect of diesel exhaust particles in vitro
    • Bayram H, Devalia JL, Khair OA etal. Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients and the effect of diesel exhaust particles in vitro. J. Allergy Clin. Immunol. 1998; 102: 771-82.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 771-782
    • Bayram, H.1    Devalia, J.L.2    Khair, O.A.3
  • 164
    • 0037080782 scopus 로고    scopus 로고
    • Asthmatic epithelial cell proliferation and stimulation of collagen production: Human asthmatic epithelial cells stimulate collagen type III production by human lung myofibroblasts after segmental allergen challenge
    • Hastie AT, Kraft WK, Nyce KB et al. Asthmatic epithelial cell proliferation and stimulation of collagen production: human asthmatic epithelial cells stimulate collagen type III production by human lung myofibroblasts after segmental allergen challenge. Am. J. Respir. Crit. Care Med. 2002; 165: 266-72.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 266-272
    • Hastie, A.T.1    Kraft, W.K.2    Nyce, K.B.3
  • 165
    • 0036037574 scopus 로고    scopus 로고
    • Effect of ozone and nitrogen dioxide on the permeability of bronchial epithelial cell cultures of non-asthmatic and asthmatic subjects
    • Bayram H, Rusznak C, Khair OA, Sapsford RJ, Abdelaziz MM. Effect of ozone and nitrogen dioxide on the permeability of bronchial epithelial cell cultures of non-asthmatic and asthmatic subjects. Clin. Exp. Allergy 2002; 32: 1285-92.
    • (2002) Clin. Exp. Allergy , vol.32 , pp. 1285-1292
    • Bayram, H.1    Rusznak, C.2    Khair, O.A.3    Sapsford, R.J.4    Abdelaziz, M.M.5
  • 166
    • 0032012938 scopus 로고    scopus 로고
    • The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro
    • Bayram H, Devalia JL, Sapsford RJ et al. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am. J. Respir. Cell Mol. Biol. 1998; 18: 441-8.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.18 , pp. 441-448
    • Bayram, H.1    Devalia, J.L.2    Sapsford, R.J.3
  • 167
    • 0035984581 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis
    • Bucchieri F, Puddicombe SM, Lordan JL et al. Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. Am. J. Respir. Cell Mol. Biol. 2002; 27: 179-85.
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.27 , pp. 179-185
    • Bucchieri, F.1    Puddicombe, S.M.2    Lordan, J.L.3
  • 168
    • 0029763302 scopus 로고    scopus 로고
    • The epithelium as a target of glucocorticoid action in the treatment of asthma
    • discussion S19-20
    • Schwiebert LM, Stellato C, Schleimer RP. The epithelium as a target of glucocorticoid action in the treatment of asthma. Am. J. Respir. Crit. Care Med. 1996; 154: S16-19 (discussion S19-20).
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154
    • Schwiebert, L.M.1    Stellato, C.2    Schleimer, R.P.3
  • 169
    • 0031075056 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action in asthma
    • Barnes PJ. Molecular mechanisms of glucocorticoid action in asthma. Pulm. Pharmacol. Ther. 1997; 10: 3-19.
    • (1997) Pulm. Pharmacol. Ther. , vol.10 , pp. 3-19
    • Barnes, P.J.1
  • 170
    • 0031698008 scopus 로고    scopus 로고
    • Anti-inflammatory effects of salmeterol compared with beclomethasone in eosinophilic mild exacerbations of asthma: A randomized, placebo controlled trial
    • Turner MO, Johnston PR, Pizzichini E, Pizzichini MM, Hussack PA, Hargreave FE. Anti-inflammatory effects of salmeterol compared with beclomethasone in eosinophilic mild exacerbations of asthma: a randomized, placebo controlled trial. Can. Respir. J. 1998; 5: 261-8.
    • (1998) Can. Respir. J. , vol.5 , pp. 261-268
    • Turner, M.O.1    Johnston, P.R.2    Pizzichini, E.3    Pizzichini, M.M.4    Hussack, P.A.5    Hargreave, F.E.6
  • 171
    • 0031724755 scopus 로고    scopus 로고
    • Induced sputum and response to glucocorticoids
    • Hargreave, FE. Induced sputum and response to glucocorticoids. J. Allergy Clin. Immunol. 1998; 102: S102-5.
    • (1998) J. Allergy Clin. Immunol. , vol.102
    • Hargreave, F.E.1
  • 173
    • 0033047819 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor expression is inhibited by glucocorticoids through post-transcriptional mechanisms
    • Grosset C, Taupin IL, Lemercier C, Moreau JF, Reiffers J, Ripoche J. Leukaemia inhibitory factor expression is inhibited by glucocorticoids through post-transcriptional mechanisms. Cytokine 1999; 11: 29-36.
    • (1999) Cytokine , vol.11 , pp. 29-36
    • Grosset, C.1    Taupin, I.L.2    Lemercier, C.3    Moreau, J.F.4    Reiffers, J.5    Ripoche, J.6
  • 174
    • 0036006808 scopus 로고    scopus 로고
    • Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells
    • Donnelly LE, Barnes PJ, Expression and regulation of inducible nitric oxide synthase from human primary airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 2002; 26: 144-511.
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.26 , pp. 144-511
    • Donnelly, L.E.1    Barnes, P.J.2
  • 178
    • 0001712741 scopus 로고    scopus 로고
    • Eosinophilic inflammation in the bronchial mucosa in children with bronchial asthma
    • Pohunek P, Roche WR, Tarzikova J, Kurdmann J, Warner JO. Eosinophilic inflammation in the bronchial mucosa in children with bronchial asthma [abstract]. Eur. Respir. J. 2000; 11 (Suppl. 25): 160s.
    • (2000) Eur. Respir. J. , vol.11 , Issue.SUPPL. 25
    • Pohunek, P.1    Roche, W.R.2    Tarzikova, J.3    Kurdmann, J.4    Warner, J.O.5
  • 179
    • 0034642066 scopus 로고    scopus 로고
    • Long-term effects of budesonide or nedocromil in children with asthma
    • The Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. N. Engl. J. Med. 2000; 343: 1054-63.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1054-1063


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