Glucocorticoid-resistant asthma and novel anti-inflammatory drugs

Drug Discovery Today

Volumn 17, Issue 17-18, 2012, Pages 1031-1038

  Keenan, Christine R ^a   Salem, Saad ^a   Fietz, Ebony R ^a   Gualano, Rosa C ^a   Stewart, Alastair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CILOMILAST; COLLAGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR BETA; GLYCOPROTEIN P; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HISTONE DEACETYLASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MULTIDRUG RESISTANCE PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; NUCLEAR RECEPTOR COACTIVATOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHODIESTERASE; ROFLUMILAST; ROLIPRAM; STAT5 PROTEIN; THEOPHYLLINE; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ASTHMA; BASOPHIL; CELL SPECIFICITY; CELL STRUCTURE; DISEASE EXACERBATION; DRUG EFFICACY; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME INHIBITION; EOSINOPHIL; EPITHELIUM CELL; FIBROBLAST; GENE TRANSLOCATION; HISTONE ACETYLATION; HUMAN; INFLAMMATORY CELL; INTRACELLULAR SIGNALING; LIGAND BINDING; LYMPHOCYTE; MACROPHAGE; NEUTROPHIL; NONHUMAN; PRESCRIPTION; PROTEIN EXPRESSION; REVIEW; SMOOTH MUSCLE FIBER; TRANSACTIVATION; VIRAL RESPIRATORY TRACT INFECTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTHMA; DRUG RESISTANCE; GLUCOCORTICOIDS; HUMANS;

EID: 84865497596     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2012.05.011     Document Type: Review

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