Overexpression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently

Journal of Molecular Medicine

Volumn 80, Issue 5, 2002, Pages 309-318

  Gougat, Claire ^a   Jaffuel, Dany ^a   Gagliardo, Rosalia ^a   Henriquet, Corinne ^a   Bousquet, Jean ^a   Demoly, Pascal ^a   Mathieu, Marc ^a,b,c  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b Centre de Pneumologie   (France)

^c CNR   (Italy)

Author keywords

Activator protein 1; Glucocorticoid receptor; Inflammation; Isoforms; Nuclear factor B

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPROTEIN; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; DEXAMETHASONE; PHORBOL 13 ACETATE 12 MYRISTATE; RECOMBINANT PROTEIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EXPRESSION VECTOR; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HORMONE ACTION; HORMONE DETERMINATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTRACELLULAR TRANSPORT; MOLECULAR RECOGNITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL STRAIN COS1; CERCOPITHECUS; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM;

ANIMAL; CERCOPITHECUS AETHIOPS; COS CELLS; DEXAMETHASONE; GENE EXPRESSION REGULATION; GENES, REPORTER; GLUCOCORTICOIDS; HUMAN; LUNG NEOPLASMS; NF-KAPPA B; RECEPTORS, GLUCOCORTICOID; RECOMBINANT PROTEINS; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; ANIMALS; HUMANS;

EID: 0036013805     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-001-0302-6     Document Type: Article

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