-
1
-
-
43049167532
-
Astaxanthin: A novel potential treatment for oxidative stress and inflammation in cardiovascular disease
-
Pashkow, F. J.; Watumull, D. G.; Campbell, C. L. Astaxanthin: A novel potential treatment for oxidative stress and inflammation in cardiovascular disease. Am. J. Cardiol. 2008, 101, 58D-68D.
-
(2008)
Am. J. Cardiol.
, vol.101
, pp. 58D-68D
-
-
Pashkow, F.J.1
Watumull, D.G.2
Campbell, C.L.3
-
2
-
-
0020017359
-
Comparison of carotenoids in the ovaries of marine fish and shellfish
-
Miki, W.; Yamaguchi, K.; Konosu, S. Comparison of carotenoids in the ovaries of marine fish and shellfish. Comp. Biochem. Physiol. B 1982, 71, 7-11.
-
(1982)
Comp. Biochem. Physiol. B
, vol.71
, pp. 7-11
-
-
Miki, W.1
Yamaguchi, K.2
Konosu, S.3
-
3
-
-
0037407158
-
Haematococcus astaxanthin: Applications for human health and nutrition
-
Guerin, M.; Huntley, M. E.; Olaizola, M. Haematococcus astaxanthin: Applications for human health and nutrition. Trends Biotechnol. 2003, 21, 210-216.
-
(2003)
Trends Biotechnol.
, vol.21
, pp. 210-216
-
-
Guerin, M.1
Huntley, M.E.2
Olaizola, M.3
-
4
-
-
84902251257
-
Amelioration of oxidative stress and protection against early brain injury by astaxanthin after experimental subarachnoid hemorrhage
-
Zhang, X. S.; Zhang, X.; Zhou, M. L.; Zhou, X. M.; Li, N.; Li, W.; Cong, Z. X.; Sun, Q.; Zhuang, Z.; Wang, C. X.; et al. Amelioration of oxidative stress and protection against early brain injury by astaxanthin after experimental subarachnoid hemorrhage. J. Neurosurg. 2014, 121, 42-54.
-
(2014)
J. Neurosurg.
, vol.121
, pp. 42-54
-
-
Zhang, X.S.1
Zhang, X.2
Zhou, M.L.3
Zhou, X.M.4
Li, N.5
Li, W.6
Cong, Z.X.7
Sun, Q.8
Zhuang, Z.9
Wang, C.X.10
-
5
-
-
56749107503
-
Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells
-
Ikeda, Y.; Tsuji, S.; Satoh, A.; Ishikura, M.; Shirasawa, T.; Shimizu, T. Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 2008, 107, 1730-1740.
-
(2008)
J. Neurochem.
, vol.107
, pp. 1730-1740
-
-
Ikeda, Y.1
Tsuji, S.2
Satoh, A.3
Ishikura, M.4
Shirasawa, T.5
Shimizu, T.6
-
6
-
-
58549103079
-
Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism
-
Liu, X.; Shibata, T.; Hisaka, S.; Osawa, T. Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism. Brain Res. 2009, 1254, 18-27.
-
(2009)
Brain Res.
, vol.1254
, pp. 18-27
-
-
Liu, X.1
Shibata, T.2
Hisaka, S.3
Osawa, T.4
-
7
-
-
67649352604
-
Astaxanthin reduces ischemic brain injury in adult rats
-
Shen, H.; Kuo, C. C.; Chou, J.; Delvolve, A.; Jackson, S. N.; Post, J.; Woods, A. S.; Hoffer, B. J.; Wang, Y.; Harvey, B. K. Astaxanthin reduces ischemic brain injury in adult rats. FASEB J. 2009, 23, 1958-1968.
-
(2009)
FASEB J.
, vol.23
, pp. 1958-1968
-
-
Shen, H.1
Kuo, C.C.2
Chou, J.3
Delvolve, A.4
Jackson, S.N.5
Post, J.6
Woods, A.S.7
Hoffer, B.J.8
Wang, Y.9
Harvey, B.K.10
-
8
-
-
84919904588
-
Astaxanthin activates nuclear factor erythroid-related factor 2 and the antioxidant responsive element (Nrf2-ARE) pathway in the brain after subarachnoid hemorrhage in rats and attenuates early brain injury
-
Wu, Q.; Zhang, X. S.; Wang, H. D.; Zhang, X.; Yu, Q.; Li, W.; Zhou, M. L.; Wang, X. L. Astaxanthin activates nuclear factor erythroid-related factor 2 and the antioxidant responsive element (Nrf2-ARE) pathway in the brain after subarachnoid hemorrhage in rats and attenuates early brain injury. Mar. Drugs 2014, 12, 6125-6141.
-
(2014)
Mar. Drugs
, vol.12
, pp. 6125-6141
-
-
Wu, Q.1
Zhang, X.S.2
Wang, H.D.3
Zhang, X.4
Yu, Q.5
Li, W.6
Zhou, M.L.7
Wang, X.L.8
-
9
-
-
84908065737
-
Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: Possible involvement of Akt/bad signaling
-
Zhang, X. S.; Zhang, X.; Wu, Q.; Li, W.; Zhang, Q. R.; Wang, C. X.; Zhou, X. M.; Li, H.; Shi, J. X.; Zhou, M. L. Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: Possible involvement of Akt/bad signaling. Mar. Drugs 2014, 12, 4291-4310.
-
(2014)
Mar. Drugs
, vol.12
, pp. 4291-4310
-
-
Zhang, X.S.1
Zhang, X.2
Wu, Q.3
Li, W.4
Zhang, Q.R.5
Wang, C.X.6
Zhou, X.M.7
Li, H.8
Shi, J.X.9
Zhou, M.L.10
-
10
-
-
77957940294
-
Neuroprotective effect of astaxanthin on H (2) O (2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo
-
Lu, Y. P.; Liu, S. Y.; Sun, H.; Wu, X. M.; Li, J. J.; Zhu, L. Neuroprotective effect of astaxanthin on H (2) O (2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo. Brain Res. 2010, 1360, 40-48.
-
(2010)
Brain Res.
, vol.1360
, pp. 40-48
-
-
Lu, Y.P.1
Liu, S.Y.2
Sun, H.3
Wu, X.M.4
Li, J.J.5
Zhu, L.6
-
11
-
-
2342431807
-
Cardioprotection and myocardial salvage by a disodium disuccinate astaxanthin derivative (Cardax)
-
Gross, G. J.; Lockwood, S. F. Cardioprotection and myocardial salvage by a disodium disuccinate astaxanthin derivative (Cardax). Life Sci. 2004, 75, 215-224.
-
(2004)
Life Sci.
, vol.75
, pp. 215-224
-
-
Gross, G.J.1
Lockwood, S.F.2
-
12
-
-
22944477087
-
Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion
-
Lauver, D. A.; Lockwood, S. F.; Lucchesi, B. R. Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. J. Pharmacol. Exp. Ther. 2005, 314, 686-692.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.314
, pp. 686-692
-
-
Lauver, D.A.1
Lockwood, S.F.2
Lucchesi, B.R.3
-
13
-
-
69749120073
-
Astaxanthin, oxidative stress, inflammation and cardiovascular disease
-
Fassett, R. G.; Coombes, J. S. Astaxanthin, oxidative stress, inflammation and cardiovascular disease. Future Cardiol. 2009, 5, 333-342.
-
(2009)
Future Cardiol.
, vol.5
, pp. 333-342
-
-
Fassett, R.G.1
Coombes, J.S.2
-
14
-
-
84879478157
-
Astaxanthin inhibits NF-kappaB and Wnt/beta-catenin signaling pathways via inactivation of Erk/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer
-
Kavitha, K.; Kowshik, J.; Kishore, T. K.; Baba, A. B.; Nagini, S. Astaxanthin inhibits NF-kappaB and Wnt/beta-catenin signaling pathways via inactivation of Erk/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer. Biochim. Biophys. Acta 2013, 1830, 4433-4444.
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 4433-4444
-
-
Kavitha, K.1
Kowshik, J.2
Kishore, T.K.3
Baba, A.B.4
Nagini, S.5
-
15
-
-
0027948638
-
Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin
-
Tanaka, T.; Morishita, Y.; Suzui, M.; Kojima, T.; Okumura, A.; Mori, H. Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis 1994, 15, 15-19.
-
(1994)
Carcinogenesis
, vol.15
, pp. 15-19
-
-
Tanaka, T.1
Morishita, Y.2
Suzui, M.3
Kojima, T.4
Okumura, A.5
Mori, H.6
-
16
-
-
79956080227
-
Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2
-
Nagendraprabhu, P.; Sudhandiran, G. Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2. Investig. New Drugs 2011, 29, 207-224.
-
(2011)
Investig. New Drugs
, vol.29
, pp. 207-224
-
-
Nagendraprabhu, P.1
Sudhandiran, G.2
-
17
-
-
79959945798
-
Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines
-
Yasui, Y.; Hosokawa, M.; Mikami, N.; Miyashita, K.; Tanaka, T. Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines. Chem. Biol. Interact. 2011, 193, 79-87.
-
(2011)
Chem. Biol. Interact.
, vol.193
, pp. 79-87
-
-
Yasui, Y.1
Hosokawa, M.2
Mikami, N.3
Miyashita, K.4
Tanaka, T.5
-
18
-
-
79959854178
-
Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARgamma) in K562 cancer cells
-
Zhang, X.; Zhao, W. E.; Hu, L.; Zhao, L.; Huang, J. Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARgamma) in K562 cancer cells. Arch. Biochem. Biophys. 2011, 512, 96-106.
-
(2011)
Arch. Biochem. Biophys.
, vol.512
, pp. 96-106
-
-
Zhang, X.1
Zhao, W.E.2
Hu, L.3
Zhao, L.4
Huang, J.5
-
19
-
-
79957974850
-
Astaxanthin induces mitochondria-mediated apoptosis in rat hepatocellular carcinoma CBRH-7919 cells
-
Song, X. D.; Zhang, J. J.; Wang, M. R.; Liu, W. B.; Gu, X. B.; Lv, C. J. Astaxanthin induces mitochondria-mediated apoptosis in rat hepatocellular carcinoma CBRH-7919 cells. Biol. Pharm. Bull. 2011, 34, 839-844.
-
(2011)
Biol. Pharm. Bull.
, vol.34
, pp. 839-844
-
-
Song, X.D.1
Zhang, J.J.2
Wang, M.R.3
Liu, W.B.4
Gu, X.B.5
Lv, C.J.6
-
20
-
-
84867208502
-
Changes in cell ultrastructure and inhibition of JAK1/STAT3 signaling pathway in CBRH-7919 cells with astaxanthin
-
Song, X.; Wang, M.; Zhang, L.; Zhang, J.; Wang, X.; Liu, W.; Gu, X.; Lv, C. Changes in cell ultrastructure and inhibition of JAK1/STAT3 signaling pathway in CBRH-7919 cells with astaxanthin. Toxicol. Mech. Methods 2012, 22, 679-686.
-
(2012)
Toxicol. Mech. Methods
, vol.22
, pp. 679-686
-
-
Song, X.1
Wang, M.2
Zhang, L.3
Zhang, J.4
Wang, X.5
Liu, W.6
Gu, X.7
Lv, C.8
-
21
-
-
40549146557
-
p66Shc, oxidative stress and aging: Importing a lifespan determinant into mitochondria
-
Pinton, P.; Rizzuto, R. p66Shc, oxidative stress and aging: Importing a lifespan determinant into mitochondria. Cell Cycle 2008, 7, 304-308.
-
(2008)
Cell Cycle
, vol.7
, pp. 304-308
-
-
Pinton, P.1
Rizzuto, R.2
-
22
-
-
84927919454
-
Inflammaging and cancer: A challenge for the mediterranean diet
-
Ostan, R.; Lanzarini, C.; Pini, E.; Scurti, M.; Vianello, D.; Bertarelli, C.; Fabbri, C.; Izzi, M.; Palmas, G.; Biondi, F.; et al. Inflammaging and Cancer: A Challenge for the Mediterranean Diet. Nutrients 2015, 7, 2589-2621.
-
(2015)
Nutrients
, vol.7
, pp. 2589-2621
-
-
Ostan, R.1
Lanzarini, C.2
Pini, E.3
Scurti, M.4
Vianello, D.5
Bertarelli, C.6
Fabbri, C.7
Izzi, M.8
Palmas, G.9
Biondi, F.10
-
23
-
-
84929325553
-
Silencing of receptor tyrosine kinase ROR1 inhibits tumor-cell proliferation via PI3K/AKT/mTOR signaling pathway in lung adenocarcinoma
-
Liu, Y.; Yang, H.; Chen, T.; Luo, Y.; Xu, Z.; Li, Y.; Yang, J. Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma. PLoS ONE 2015, 10, e0127092.
-
(2015)
PLoS ONE
, vol.10
, pp. e0127092
-
-
Liu, Y.1
Yang, H.2
Chen, T.3
Luo, Y.4
Xu, Z.5
Li, Y.6
Yang, J.7
-
24
-
-
84929676288
-
Combining CAL-101 with celecoxib enhances apoptosis of EBV-transformed B-cells through MAPK-induced ER stress
-
Park, G. B.; Hur, D. Y.; Kim, D. Combining CAL-101 with Celecoxib Enhances Apoptosis of EBV-transformed B-Cells Through MAPK-induced ER Stress. Anticancer Res. 2015, 35, 2699-2708.
-
(2015)
Anticancer Res.
, vol.35
, pp. 2699-2708
-
-
Park, G.B.1
Hur, D.Y.2
Kim, D.3
-
25
-
-
84938228234
-
Let-7a regulates mammosphere formation capacity through Ras/NF-kappaB and Ras/MAPK/ERK pathway in breast cancer stem cells
-
Xu, C.; Sun, X.; Qin, S.; Zheng, Z.; Xu, S.; Luo, G.; Liu, P.; Du, N.; Zhang, Y.; Liu, D.; et al. Let-7a regulates mammosphere formation capacity through Ras/NF-kappaB and Ras/MAPK/ERK pathway in breast cancer stem cells. Cell Cycle 2015, 14, 1686-1697.
-
(2015)
Cell Cycle
, vol.14
, pp. 1686-1697
-
-
Xu, C.1
Sun, X.2
Qin, S.3
Zheng, Z.4
Xu, S.5
Luo, G.6
Liu, P.7
Du, N.8
Zhang, Y.9
Liu, D.10
-
26
-
-
0030045346
-
Cell migration: A physically integrated molecular process
-
Lauffenburger, D. A.; Horwitz, A. F. Cell migration: A physically integrated molecular process. Cell 1996, 84, 359-369.
-
(1996)
Cell
, vol.84
, pp. 359-369
-
-
Lauffenburger, D.A.1
Horwitz, A.F.2
-
27
-
-
84907821820
-
Astaxanthin inhibits JAK/STAT-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer
-
Kowshik, J.; Baba, A. B.; Giri, H.; Deepak Reddy, G.; Dixit, M.; Nagini, S. Astaxanthin inhibits JAK/STAT-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer. PLoS ONE 2014, 9, e109114.
-
(2014)
PLoS ONE
, vol.9
, pp. e109114
-
-
Kowshik, J.1
Baba, A.B.2
Giri, H.3
Deepak Reddy, G.4
Dixit, M.5
Nagini, S.6
-
28
-
-
67650450196
-
Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells
-
Palozza, P.; Torelli, C.; Boninsegna, A.; Simone, R.; Catalano, A.; Mele, M. C.; Picci, N. Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. Cancer Lett. 2009, 283, 108-117.
-
(2009)
Cancer Lett.
, vol.283
, pp. 108-117
-
-
Palozza, P.1
Torelli, C.2
Boninsegna, A.3
Simone, R.4
Catalano, A.5
Mele, M.C.6
Picci, N.7
-
29
-
-
79960706234
-
Apoptosis and other cell death mechanisms after retinal detachment: Implications for photoreceptor rescue
-
Lo, A. C.; Woo, T. T.; Wong, R. L.; Wong, D. Apoptosis and other cell death mechanisms after retinal detachment: Implications for photoreceptor rescue. Ophthalmologica 2011, 226(Suppl. 1), 10-17.
-
(2011)
Ophthalmologica
, vol.226
, pp. 10-17
-
-
Lo, A.C.1
Woo, T.T.2
Wong, R.L.3
Wong, D.4
-
30
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
Elmore, S. Apoptosis: A review of programmed cell death. Toxicol. Pathol. 2007, 35, 495-516.
-
(2007)
Toxicol. Pathol.
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
31
-
-
13844281636
-
Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury
-
Zhang, X.; Chen, Y.; Jenkins, L. W.; Kochanek, P. M.; Clark, R. S. Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury. Crit. Care 2005, 9, 66-75.
-
(2005)
Crit. Care
, vol.9
, pp. 66-75
-
-
Zhang, X.1
Chen, Y.2
Jenkins, L.W.3
Kochanek, P.M.4
Clark, R.S.5
-
32
-
-
84868197448
-
Programmed cell death pathways in cancer: A review of apoptosis, autophagy and programmed necrosis
-
Ouyang, L.; Shi, Z.; Zhao, S.; Wang, F. T.; Zhou, T. T.; Liu, B.; Bao, J. K. Programmed cell death pathways in cancer: A review of apoptosis, autophagy and programmed necrosis. Cell Prolif. 2012, 45, 487-498.
-
(2012)
Cell Prolif.
, vol.45
, pp. 487-498
-
-
Ouyang, L.1
Shi, Z.2
Zhao, S.3
Wang, F.T.4
Zhou, T.T.5
Liu, B.6
Bao, J.K.7
-
33
-
-
0030950228
-
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis
-
Hu, S.; Vincenz, C.; Buller, M.; Dixit, V. M. A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis. J. Biol. Chem. 1997, 272, 9621-9624.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9621-9624
-
-
Hu, S.1
Vincenz, C.2
Buller, M.3
Dixit, V.M.4
-
34
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen, G. M. Caspases: The executioners of apoptosis. Biochem. J. 1997, 326(Pt 1), 1-16.
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
35
-
-
84908153270
-
Targeting antioxidants for cancer therapy
-
Glasauer, A.; Chandel, N. S. Targeting antioxidants for cancer therapy. Biochem. Pharmacol. 2014, 92, 90-101.
-
(2014)
Biochem. Pharmacol.
, vol.92
, pp. 90-101
-
-
Glasauer, A.1
Chandel, N.S.2
-
36
-
-
79251517382
-
Regulation of cancer cell metabolism
-
Cairns, R. A.; Harris, I. S.; Mak, T. W. Regulation of cancer cell metabolism. Nat. Rev. Cancer 2011, 11, 85-95.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 85-95
-
-
Cairns, R.A.1
Harris, I.S.2
Mak, T.W.3
-
37
-
-
84895821685
-
Astaxanthin treatment confers protection against oxidative stress in U937 cells stimulated with lipopolysaccharide reducing O2-production
-
Franceschelli, S.; Pesce, M.; Ferrone, A.; de Lutiis, M. A.; Patruno, A.; Grilli, A.; Felaco, M.; Speranza, L. Astaxanthin treatment confers protection against oxidative stress in U937 cells stimulated with lipopolysaccharide reducing O2-production. PLoS ONE 2014, 9, e88359.
-
(2014)
PLoS ONE
, vol.9
, pp. e88359
-
-
Franceschelli, S.1
Pesce, M.2
Ferrone, A.3
De Lutiis, M.A.4
Patruno, A.5
Grilli, A.6
Felaco, M.7
Speranza, L.8
-
38
-
-
77956181267
-
Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway
-
Kim, K. N.; Heo, S. J.; Kang, S. M.; Ahn, G.; Jeon, Y. J. Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. Toxicol. in Vitro 2010, 24, 1648-1654.
-
(2010)
Toxicol. in Vitro
, vol.24
, pp. 1648-1654
-
-
Kim, K.N.1
Heo, S.J.2
Kang, S.M.3
Ahn, G.4
Jeon, Y.J.5
-
39
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill, F.; Mantovani, A. Inflammation and cancer: Back to Virchow? Lancet 2001, 357, 539-545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
40
-
-
0033911488
-
Inflamm-aging. An evolutionary perspective on immunosenescence
-
Franceschi, C.; Bonafe, M.; Valensin, S.; Olivieri, F.; de Luca, M.; Ottaviani, E.; de Benedictis, G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 2000, 908, 244-254.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
Olivieri, F.4
De Luca, M.5
Ottaviani, E.6
De Benedictis, G.7
-
41
-
-
39649085837
-
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
-
Franceschi, C. Inflammaging as a major characteristic of old people: Can it be prevented or cured? Nutr. Rev. 2007, 65(12 Pt 2), S173-S176.
-
(2007)
Nutr. Rev.
, vol.65
, Issue.12
, pp. S173-S176
-
-
Franceschi, C.1
-
42
-
-
33846111415
-
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
-
Franceschi, C.; Capri, M.; Monti, D.; Giunta, S.; Olivieri, F.; Sevini, F.; Panourgia, M. P.; Invidia, L.; Celani, L.; Scurti, M.; et al. Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans. Mech. Ageing Dev. 2007, 128, 92-105.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 92-105
-
-
Franceschi, C.1
Capri, M.2
Monti, D.3
Giunta, S.4
Olivieri, F.5
Sevini, F.6
Panourgia, M.P.7
Invidia, L.8
Celani, L.9
Scurti, M.10
-
43
-
-
84871925936
-
Inflamm-ageing
-
Cevenini, E.; Monti, D.; Franceschi, C. Inflamm-ageing. Curr. Opin. Clin. Nutr. Metab. Care 2013, 16, 14-20.
-
(2013)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.16
, pp. 14-20
-
-
Cevenini, E.1
Monti, D.2
Franceschi, C.3
-
44
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M.; Werb, Z. Inflammation and cancer. Nature 2002, 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
45
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani, A.; Allavena, P.; Sica, A.; Balkwill, F. Cancer-related inflammation. Nature 2008, 454, 436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
46
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin, M. Nuclear factor-kappaB in cancer development and progression. Nature 2006, 441, 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
47
-
-
84867101876
-
Aspirin as adjuvant therapy for colorectal cancer-Reinterpreting paradigms
-
Chia, W. K.; Ali, R.; Toh, H. C. Aspirin as adjuvant therapy for colorectal cancer-Reinterpreting paradigms. Nat. Rev. Clin. Oncol. 2012, 9, 561-570.
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 561-570
-
-
Chia, W.K.1
Ali, R.2
Toh, H.C.3
-
48
-
-
84893425203
-
The immune contexture of primary and metastatic human tumours
-
Giraldo, N. A.; Becht, E.; Remark, R.; Damotte, D.; Sautes-Fridman, C.; Fridman, W. H. The immune contexture of primary and metastatic human tumours. Curr. Opin. Immunol. 2014, 27, 8-15.
-
(2014)
Curr. Opin. Immunol.
, vol.27
, pp. 8-15
-
-
Giraldo, N.A.1
Becht, E.2
Remark, R.3
Damotte, D.4
Sautes-Fridman, C.5
Fridman, W.H.6
-
49
-
-
84860644483
-
Astaxanthin treatment reduced oxidative induced pro-inflammatory cytokines secretion in U937: SHP-1 as a novel biological target
-
Speranza, L.; Pesce, M.; Patruno, A.; Franceschelli, S.; de Lutiis, M. A.; Grilli, A.; Felaco, M. Astaxanthin treatment reduced oxidative induced pro-inflammatory cytokines secretion in U937: SHP-1 as a novel biological target. Mar. Drugs 2012, 10, 890-899.
-
(2012)
Mar. Drugs
, vol.10
, pp. 890-899
-
-
Speranza, L.1
Pesce, M.2
Patruno, A.3
Franceschelli, S.4
De Lutiis, M.A.5
Grilli, A.6
Felaco, M.7
-
50
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl, P.; Wolf, K. Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat. Rev. Cancer 2003, 3, 362-374.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
51
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
Nguyen, D. X.; Massague, J. Genetic determinants of cancer metastasis. Nat. Rev. Genet. 2007, 8, 341-352.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
52
-
-
5044238876
-
Integrin signalling during tumour progression
-
Guo, W.; Giancotti, F. G. Integrin signalling during tumour progression. Nat. Rev. Mol. Cell Biol. 2004, 5, 816-826.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 816-826
-
-
Guo, W.1
Giancotti, F.G.2
-
53
-
-
78651270612
-
Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2-9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways
-
Lu, K. W.; Chen, J. C.; Lai, T. Y.; Yang, J. S.; Weng, S. W.; Ma, Y. S.; Lu, P. J.; Weng, J. R.; Chueh, F. S.; Wood, W. G.; et al. Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2-9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways. Hum. Exp. Toxicol. 2011, 30, 406-415.
-
(2011)
Hum. Exp. Toxicol.
, vol.30
, pp. 406-415
-
-
Lu, K.W.1
Chen, J.C.2
Lai, T.Y.3
Yang, J.S.4
Weng, S.W.5
Ma, Y.S.6
Lu, P.J.7
Weng, J.R.8
Chueh, F.S.9
Wood, W.G.10
-
54
-
-
0034615550
-
Tissue inhibitors of metalloproteinases: Evolution, structure and function
-
Brew, K.; Dinakarpandian, D.; Nagase, H. Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta 2000, 1477, 267-283.
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 267-283
-
-
Brew, K.1
Dinakarpandian, D.2
Nagase, H.3
-
55
-
-
0034599893
-
Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture
-
Kozuki, Y.; Miura, Y.; Yagasaki, K. Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture. Cancer Lett. 2000, 151, 111-115.
-
(2000)
Cancer Lett.
, vol.151
, pp. 111-115
-
-
Kozuki, Y.1
Miura, Y.2
Yagasaki, K.3
-
56
-
-
84901308106
-
Regulation of gap junction channels by infectious agents and inflammation in the CNS
-
Castellano, P.; Eugenin, E. A. Regulation of gap junction channels by infectious agents and inflammation in the CNS. Front. Cell Neurosci. 2014, 8, 122.
-
(2014)
Front. Cell Neurosci.
, vol.8
, pp. 122
-
-
Castellano, P.1
Eugenin, E.A.2
-
57
-
-
0035991948
-
Gap junctions: Structure and function (Review)
-
Evans, W. H.; Martin, P. E. Gap junctions: Structure and function (Review). Mol. Membr. Biol. 2002, 19, 121-136.
-
(2002)
Mol. Membr. Biol.
, vol.19
, pp. 121-136
-
-
Evans, W.H.1
Martin, P.E.2
-
58
-
-
1942470517
-
The effects of connexin phosphorylation on gap junctional communication
-
Lampe, P. D.; Lau, A. F. The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 2004, 36, 1171-1186.
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 1171-1186
-
-
Lampe, P.D.1
Lau, A.F.2
-
59
-
-
0035985057
-
Structural and functional diversity of connexin genes in the mouse and human genome
-
Willecke, K.; Eiberger, J.; Degen, J.; Eckardt, D.; Romualdi, A.; Guldenagel, M.; Deutsch, U.; Sohl, G. Structural and functional diversity of connexin genes in the mouse and human genome. Biol. Chem. 2002, 383, 725-737.
-
(2002)
Biol. Chem.
, vol.383
, pp. 725-737
-
-
Willecke, K.1
Eiberger, J.2
Degen, J.3
Eckardt, D.4
Romualdi, A.5
Guldenagel, M.6
Deutsch, U.7
Sohl, G.8
-
60
-
-
2942519505
-
Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives
-
Hix, L. M.; Lockwood, S. F.; Bertram, J. S. Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives. Cancer Lett. 2004, 211, 25-37.
-
(2004)
Cancer Lett.
, vol.211
, pp. 25-37
-
-
Hix, L.M.1
Lockwood, S.F.2
Bertram, J.S.3
-
61
-
-
24144433471
-
Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative
-
Hix, L. M.; Frey, D. A.; McLaws, M. D.; Osterlie, M.; Lockwood, S. F.; Bertram, J. S. Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative. Carcinogenesis 2005, 26, 1634-1641.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1634-1641
-
-
Hix, L.M.1
Frey, D.A.2
McLaws, M.D.3
Osterlie, M.4
Lockwood, S.F.5
Bertram, J.S.6
-
62
-
-
31544477402
-
Astaxanthin diminishes gap junctional intercellular communication in primary human fibroblasts
-
Daubrawa, F.; Sies, H.; Stahl, W. Astaxanthin diminishes gap junctional intercellular communication in primary human fibroblasts. J. Nutr. 2005, 135, 2507-2511.
-
(2005)
J. Nutr.
, vol.135
, pp. 2507-2511
-
-
Daubrawa, F.1
Sies, H.2
Stahl, W.3
-
63
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
Karin, M.; Greten, F. R. NF-kappaB: Linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 2005, 5, 749-759.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
64
-
-
33750454819
-
Mutations in the NF-kappaB signaling pathway: Implications for human disease
-
Courtois, G.; Gilmore, T. D. Mutations in the NF-kappaB signaling pathway: Implications for human disease. Oncogene 2006, 25, 6831-6843.
-
(2006)
Oncogene
, vol.25
, pp. 6831-6843
-
-
Courtois, G.1
Gilmore, T.D.2
-
65
-
-
72749126288
-
NF-kappaB signalling proteins p50/p105, p52/p100, RelA, and IKKepsilon are over-expressed in oesophageal squamous cell carcinomas
-
Kang, M. R.; Kim, M. S.; Kim, S. S.; Ahn, C. H.; Yoo, N. J.; Lee, S. H. NF-kappaB signalling proteins p50/p105, p52/p100, RelA, and IKKepsilon are over-expressed in oesophageal squamous cell carcinomas. Pathology 2009, 41, 622-625.
-
(2009)
Pathology
, vol.41
, pp. 622-625
-
-
Kang, M.R.1
Kim, M.S.2
Kim, S.S.3
Ahn, C.H.4
Yoo, N.J.5
Lee, S.H.6
-
66
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin, M.; Lin, A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 2002, 3, 221-227.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
67
-
-
79551639050
-
Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
-
Wilken, R.; Veena, M. S.; Wang, M. B.; Srivatsan, E. S. Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol. Cancer 2011, 10, 12.
-
(2011)
Mol. Cancer
, vol.10
, pp. 12
-
-
Wilken, R.1
Veena, M.S.2
Wang, M.B.3
Srivatsan, E.S.4
-
68
-
-
37249073366
-
Perspectives on c-Myc, Cyclin D1, and their interaction in cancer formation, progression, and response to chemotherapy
-
Liao, D. J.; Thakur, A.; Wu, J.; Biliran, H.; Sarkar, F. H. Perspectives on c-Myc, Cyclin D1, and their interaction in cancer formation, progression, and response to chemotherapy. Crit. Rev. Oncog. 2007, 13, 93-158.
-
(2007)
Crit. Rev. Oncog.
, vol.13
, pp. 93-158
-
-
Liao, D.J.1
Thakur, A.2
Wu, J.3
Biliran, H.4
Sarkar, F.H.5
-
69
-
-
58149346175
-
Resveratrol addiction: To die or not to die
-
Shakibaei, M.; Harikumar, K. B.; Aggarwal, B. B. Resveratrol addiction: To die or not to die. Mol. Nutr. Food Res. 2009, 53, 115-128.
-
(2009)
Mol. Nutr. Food Res.
, vol.53
, pp. 115-128
-
-
Shakibaei, M.1
Harikumar, K.B.2
Aggarwal, B.B.3
-
70
-
-
53549089886
-
Inflammatory processes in preterm and term parturition
-
Christiaens, I.; Zaragoza, D. B.; Guilbert, L.; Robertson, S. A.; Mitchell, B. F.; Olson, D. M. Inflammatory processes in preterm and term parturition. J. Reprod. Immunol. 2008, 79, 50-57.
-
(2008)
J. Reprod. Immunol.
, vol.79
, pp. 50-57
-
-
Christiaens, I.1
Zaragoza, D.B.2
Guilbert, L.3
Robertson, S.A.4
Mitchell, B.F.5
Olson, D.M.6
-
71
-
-
49749124618
-
Molecular links between tumor angiogenesis and inflammation: Inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy
-
Ono, M. Molecular links between tumor angiogenesis and inflammation: Inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy. Cancer Sci. 2008, 99, 1501-1506.
-
(2008)
Cancer Sci.
, vol.99
, pp. 1501-1506
-
-
Ono, M.1
-
72
-
-
78149259518
-
Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents
-
Gupta, S. C.; Prasad, S.; Reuter, S.; Kannappan, R.; Yadav, V. R.; Ravindran, J.; Hema, P. S.; Chaturvedi, M. M.; Nair, M.; Aggarwal, B. B. Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents. J. Biol. Chem. 2010, 285, 35406-35417.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35406-35417
-
-
Gupta, S.C.1
Prasad, S.2
Reuter, S.3
Kannappan, R.4
Yadav, V.R.5
Ravindran, J.6
Hema, P.S.7
Chaturvedi, M.M.8
Nair, M.9
Aggarwal, B.B.10
-
73
-
-
84907212785
-
Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-kappaB, Beclin-1, p62 and NBR1) in human bladder cancer cells
-
Ishaq, M.; Khan, M. A.; Sharma, K.; Sharma, G.; Dutta, R. K.; Majumdar, S. Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-kappaB, Beclin-1, p62 and NBR1) in human bladder cancer cells. Biochim. Biophys. Acta 2014, 1840, 3374-3384.
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 3374-3384
-
-
Ishaq, M.1
Khan, M.A.2
Sharma, K.3
Sharma, G.4
Dutta, R.K.5
Majumdar, S.6
-
74
-
-
2342445635
-
The JAK/STAT signaling pathway
-
Rawlings, J. S.; Rosler, K. M.; Harrison, D. A. The JAK/STAT signaling pathway. J. Cell Sci. 2004, 117, 1281-1283.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1281-1283
-
-
Rawlings, J.S.1
Rosler, K.M.2
Harrison, D.A.3
-
75
-
-
0031919849
-
Jaks and STATs: Biological implications
-
Leonard, W. J.; O'Shea, J. J. Jaks and STATs: Biological implications. Annu. Rev. Immunol. 1998, 16, 293-322.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
76
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler, C.; Darnell, J. E., Jr. Transcriptional responses to polypeptide ligands: The JAK-STAT pathway. Annu. Rev. Biochem. 1995, 64, 621-651.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell, J.E.J.2
-
77
-
-
84872065897
-
JAKs and STATs in immunity, immunodeficiency, and cancer
-
O'Shea, J. J.; Holland, S. M.; Staudt, L. M. JAKs and STATs in immunity, immunodeficiency, and cancer. N. Engl. J. Med. 2013, 368, 161-170.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 161-170
-
-
O'Shea, J.J.1
Holland, S.M.2
Staudt, L.M.3
-
78
-
-
78649710769
-
Mast cell homeostasis and the JAK-STAT pathway
-
Morales, J. K.; Falanga, Y. T.; Depcrynski, A.; Fernando, J.; Ryan, J. J. Mast cell homeostasis and the JAK-STAT pathway. Genes Immun. 2010, 11, 599-608.
-
(2010)
Genes Immun.
, vol.11
, pp. 599-608
-
-
Morales, J.K.1
Falanga, Y.T.2
Depcrynski, A.3
Fernando, J.4
Ryan, J.J.5
-
79
-
-
77954733222
-
JAK/STAT signaling in renal diseases
-
Chuang, P. Y.; He, J. C. JAK/STAT signaling in renal diseases. Kidney Int. 2010, 78, 231-234.
-
(2010)
Kidney Int.
, vol.78
, pp. 231-234
-
-
Chuang, P.Y.1
He, J.C.2
-
80
-
-
56049089150
-
Role of hepatic STAT3 in the regulation of lipid metabolism
-
Kinoshita, S.; Ogawa, W.; Okamoto, Y.; Takashima, M.; Inoue, H.; Matsuki, Y.; Watanabe, E.; Hiramatsu, R.; Kasuga, M. Role of hepatic STAT3 in the regulation of lipid metabolism. Kobe J. Med. Sci. 2008, 54, E200-E208.
-
(2008)
Kobe J. Med. Sci.
, vol.54
, pp. E200-E208
-
-
Kinoshita, S.1
Ogawa, W.2
Okamoto, Y.3
Takashima, M.4
Inoue, H.5
Matsuki, Y.6
Watanabe, E.7
Hiramatsu, R.8
Kasuga, M.9
-
81
-
-
79959549307
-
JAK-STAT signaling in hepatic fibrosis
-
Mair, M.; Blaas, L.; Osterreicher, C. H.; Casanova, E.; Eferl, R. JAK-STAT signaling in hepatic fibrosis. Front. Biosci. Landmark Ed. 2011, 16, 2794-2811.
-
(2011)
Front. Biosci. Landmark Ed.
, vol.16
, pp. 2794-2811
-
-
Mair, M.1
Blaas, L.2
Osterreicher, C.H.3
Casanova, E.4
Eferl, R.5
-
82
-
-
84937036056
-
JAK-STAT in lipid metabolism of adipocytes
-
Xu, D.; Yin, C.; Wang, S.; Xiao, Y. JAK-STAT in lipid metabolism of adipocytes. JAKSTAT 2013, 2, e27203.
-
(2013)
JAKSTAT
, vol.2
, pp. e27203
-
-
Xu, D.1
Yin, C.2
Wang, S.3
Xiao, Y.4
-
83
-
-
84929590465
-
Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3
-
Zhu, S.; Wang, Z.; Li, Z.; Peng, H.; Luo, Y.; Deng, M.; Li, R.; Dai, C.; Xu, Y.; Liu, S.; et al. Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3. Oncotarget 2015, 6, 10460-10472.
-
(2015)
Oncotarget
, vol.6
, pp. 10460-10472
-
-
Zhu, S.1
Wang, Z.2
Li, Z.3
Peng, H.4
Luo, Y.5
Deng, M.6
Li, R.7
Dai, C.8
Xu, Y.9
Liu, S.10
-
84
-
-
84934761520
-
Targeting the innate immune system as immunotherapy for acute myeloid leukemia
-
Curran, E.; Corrales, L.; Kline, J. Targeting the innate immune system as immunotherapy for acute myeloid leukemia. Front. Oncol. 2015, 5, 83.
-
(2015)
Front. Oncol.
, vol.5
, pp. 83
-
-
Curran, E.1
Corrales, L.2
Kline, J.3
-
85
-
-
84937228085
-
Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy
-
Bosch-Barrera, J.; Menendez, J. A. Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy. Cancer Treat. Rev. 2015, 41, 540-546.
-
(2015)
Cancer Treat. Rev.
, vol.41
, pp. 540-546
-
-
Bosch-Barrera, J.1
Menendez, J.A.2
-
86
-
-
0034941816
-
The role of Epstein-Barr virus in neoplastic transformation
-
Knecht, H.; Berger, C.; Rothenberger, S.; Odermatt, B. F.; Brousset, P. The role of Epstein-Barr virus in neoplastic transformation. Oncology 2001, 60, 289-302.
-
(2001)
Oncology
, vol.60
, pp. 289-302
-
-
Knecht, H.1
Berger, C.2
Rothenberger, S.3
Odermatt, B.F.4
Brousset, P.5
-
87
-
-
78650923969
-
Akt is required for Stat5 activation and mammary differentiation
-
Chen, C. C.; Boxer, R. B.; Stairs, D. B.; Portocarrero, C. P.; Horton, R. H.; Alvarez, J. V.; Birnbaum, M. J.; Chodosh, L. A. Akt is required for Stat5 activation and mammary differentiation. Breast Cancer Res. 2010, 12, R72.
-
(2010)
Breast Cancer Res.
, vol.12
, pp. R72
-
-
Chen, C.C.1
Boxer, R.B.2
Stairs, D.B.3
Portocarrero, C.P.4
Horton, R.H.5
Alvarez, J.V.6
Birnbaum, M.J.7
Chodosh, L.A.8
-
88
-
-
84907368130
-
JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo
-
Gallipoli, P.; Cook, A.; Rhodes, S.; Hopcroft, L.; Wheadon, H.; Whetton, A. D.; Jorgensen, H. G.; Bhatia, R.; Holyoake, T. L. JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo. Blood 2014, 124, 1492-501.
-
(2014)
Blood
, vol.124
, pp. 1492-1501
-
-
Gallipoli, P.1
Cook, A.2
Rhodes, S.3
Hopcroft, L.4
Wheadon, H.5
Whetton, A.D.6
Jorgensen, H.G.7
Bhatia, R.8
Holyoake, T.L.9
-
89
-
-
84945990416
-
Targeting the PI3K/AKT/mTOR pathway: Biomarkers of success and tribulation
-
Owonikoko, T. K.; Khuri, F. R. Targeting the PI3K/AKT/mTOR pathway: Biomarkers of success and tribulation. Am. Soc. Clin. Oncol. Educ. Book 2013, 33, e395.
-
(2013)
Am. Soc. Clin. Oncol. Educ. Book
, vol.33
, pp. e395
-
-
Owonikoko, T.K.1
Khuri, F.R.2
-
90
-
-
79952495236
-
Mammalian target of rapamycin: Biological function and target for novel anticancer agents
-
Borders, E. B.; Bivona, C.; Medina, P. J. Mammalian target of rapamycin: Biological function and target for novel anticancer agents. Am. J. Health Syst. Pharm. 2010, 67, 2095-2106.
-
(2010)
Am. J. Health Syst. Pharm.
, vol.67
, pp. 2095-2106
-
-
Borders, E.B.1
Bivona, C.2
Medina, P.J.3
-
91
-
-
51449095342
-
Targeting the PI3K-AKT-mTOR pathway: Progress, pitfalls, and promises
-
Yap, T. A.; Garrett, M. D.; Walton, M. I.; Raynaud, F.; de Bono, J. S.; Workman, P. Targeting the PI3K-AKT-mTOR pathway: Progress, pitfalls, and promises. Curr. Opin. Pharmacol. 2008, 8, 393-412.
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 393-412
-
-
Yap, T.A.1
Garrett, M.D.2
Walton, M.I.3
Raynaud, F.4
De Bono, J.S.5
Workman, P.6
-
92
-
-
84883470363
-
microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2
-
Liao, W. T.; Li, T. T.; Wang, Z. G.; Wang, S. Y.; He, M. R.; Ye, Y. P.; Qi, L.; Cui, Y. M.; Wu, P.; Jiao, H. L.; et al. microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2. Clin. Cancer Res. 2013, 19, 4662-4672.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 4662-4672
-
-
Liao, W.T.1
Li, T.T.2
Wang, Z.G.3
Wang, S.Y.4
He, M.R.5
Ye, Y.P.6
Qi, L.7
Cui, Y.M.8
Wu, P.9
Jiao, H.L.10
-
93
-
-
84866522619
-
The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells
-
Zheng, J.; Zou, X.; Yao, J. The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells. Chemotherapy 2012, 58, 273-281.
-
(2012)
Chemotherapy
, vol.58
, pp. 273-281
-
-
Zheng, J.1
Zou, X.2
Yao, J.3
-
94
-
-
84891486267
-
Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy
-
Yothaisong, S.; Dokduang, H.; Techasen, A.; Namwat, N.; Yongvanit, P.; Bhudhisawasdi, V.; Puapairoj, A.; Riggins, G. J.; Loilome, W. Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy. Tumour Biol. 2013, 34, 3637-3648.
-
(2013)
Tumour Biol.
, vol.34
, pp. 3637-3648
-
-
Yothaisong, S.1
Dokduang, H.2
Techasen, A.3
Namwat, N.4
Yongvanit, P.5
Bhudhisawasdi, V.6
Puapairoj, A.7
Riggins, G.J.8
Loilome, W.9
-
95
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G.; Whyte, D. B.; Martinez, R.; Hunter, T.; Sudarsanam, S. The protein kinase complement of the human genome. Science 2002, 298, 1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
96
-
-
76549115938
-
MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP
-
Younce, C. W.; Kolattukudy, P. E. MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP. Biochem. J. 2010, 426, 43-53.
-
(2010)
Biochem. J.
, vol.426
, pp. 43-53
-
-
Younce, C.W.1
Kolattukudy, P.E.2
-
97
-
-
84862309959
-
Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: Ameliorating effects of (-)-epigallocatechin-3-gallate
-
Yan, J.; Feng, Z.; Liu, J.; Shen, W.; Wang, Y.; Wertz, K.; Weber, P.; Long, J.; Liu, J. Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: Ameliorating effects of (-)-epigallocatechin-3-gallate. J. Nutr. Biochem. 2012, 23, 716-724.
-
(2012)
J. Nutr. Biochem.
, vol.23
, pp. 716-724
-
-
Yan, J.1
Feng, Z.2
Liu, J.3
Shen, W.4
Wang, Y.5
Wertz, K.6
Weber, P.7
Long, J.8
Liu, J.9
-
98
-
-
84863142691
-
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK
-
Fan, S.; Qi, M.; Yu, Y.; Li, L.; Yao, G.; Tashiro, S.; Onodera, S.; Ikejima, T. P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK. Free Radic. Res. 2012, 46, 310-319.
-
(2012)
Free Radic. Res.
, vol.46
, pp. 310-319
-
-
Fan, S.1
Qi, M.2
Yu, Y.3
Li, L.4
Yao, G.5
Tashiro, S.6
Onodera, S.7
Ikejima, T.8
-
99
-
-
84938269160
-
ANXA1 silencing increases the sensitivity of cancer cells to low-concentration arsenic trioxide treatment by inhibiting ERK MAPK activation
-
Zhang, X.; Li, X.; Li, X.; Zheng, L.; Lei, L. ANXA1 silencing increases the sensitivity of cancer cells to low-concentration arsenic trioxide treatment by inhibiting ERK MAPK activation. Tumori 2015, 101, doi:10.5301/tj.5000315.
-
(2015)
Tumori
, vol.101
-
-
Zhang, X.1
Li, X.2
Li, X.3
Zheng, L.4
Lei, L.5
-
100
-
-
84931047328
-
Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway
-
Baek, S. H.; Kim, C.; Lee, J. H.; Nam, D.; Lee, J.; Lee, S. G.; Chung, W. S.; Jang, H. J.; Kim, S. H.; Ahn, K. S. Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway. Immunopharmacol. Immunotoxicol. 2015, 37, 265-273.
-
(2015)
Immunopharmacol. Immunotoxicol.
, vol.37
, pp. 265-273
-
-
Baek, S.H.1
Kim, C.2
Lee, J.H.3
Nam, D.4
Lee, J.5
Lee, S.G.6
Chung, W.S.7
Jang, H.J.8
Kim, S.H.9
Ahn, K.S.10
-
101
-
-
84925515308
-
Role of PPAR gamma in the Differentiation and Function of Neurons
-
Quintanilla, R. A.; Utreras, E.; Cabezas-Opazo, F. A. Role of PPAR gamma in the Differentiation and Function of Neurons. PPAR Res. 2014, 2014, 768594.
-
(2014)
PPAR Res.
, vol.2014
, pp. 768594
-
-
Quintanilla, R.A.1
Utreras, E.2
Cabezas-Opazo, F.A.3
-
102
-
-
84871393949
-
Targeting PPARgamma Signaling Cascade for the Prevention and Treatment of Prostate Cancer
-
Sikka, S.; Chen, L.; Sethi, G.; Kumar, A. P. Targeting PPARgamma Signaling Cascade for the Prevention and Treatment of Prostate Cancer. PPAR Res. 2012, 2012, 968040.
-
(2012)
PPAR Res.
, vol.2012
, pp. 968040
-
-
Sikka, S.1
Chen, L.2
Sethi, G.3
Kumar, A.P.4
-
103
-
-
0034847431
-
Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs)
-
Sporn, M. B.; Suh, N.; Mangelsdorf, D. J. Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs). Trends Mol. Med. 2001, 7, 395-400.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 395-400
-
-
Sporn, M.B.1
Suh, N.2
Mangelsdorf, D.J.3
-
104
-
-
80054692069
-
PPARgamma disease gene network and identification of therapeutic targets for prostate cancer
-
Venkatachalam, G.; Kumar, A. P.; Sakharkar, K. R.; Thangavel, S.; Clement, M. V.; Sakharkar, M. K. PPARgamma disease gene network and identification of therapeutic targets for prostate cancer. J. Drug Target. 2011, 19, 781-796.
-
(2011)
J. Drug Target.
, vol.19
, pp. 781-796
-
-
Venkatachalam, G.1
Kumar, A.P.2
Sakharkar, K.R.3
Thangavel, S.4
Clement, M.V.5
Sakharkar, M.K.6
-
105
-
-
13444292545
-
15-deoxy-Delta-12, 14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism
-
Pignatelli, M.; Sanchez-Rodriguez, J.; Santos, A.; Perez-Castillo, A. 15-deoxy-Delta-12, 14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism. Carcinogenesis 2005, 26, 81-92.
-
(2005)
Carcinogenesis
, vol.26
, pp. 81-92
-
-
Pignatelli, M.1
Sanchez-Rodriguez, J.2
Santos, A.3
Perez-Castillo, A.4
-
106
-
-
84931044554
-
Deregulation of PPARbeta/delta target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment
-
Schumann, T.; Adhikary, T.; Wortmann, A.; Finkernagel, F.; Lieber, S.; Schnitzer, E.; Legrand, N.; Schober, Y.; Nockher, W. A.; Toth, P. M.; et al. Deregulation of PPARbeta/delta target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment. Oncotarget 2015, 6, 13416-13433.
-
(2015)
Oncotarget
, vol.6
, pp. 13416-13433
-
-
Schumann, T.1
Adhikary, T.2
Wortmann, A.3
Finkernagel, F.4
Lieber, S.5
Schnitzer, E.6
Legrand, N.7
Schober, Y.8
Nockher, W.A.9
Toth, P.M.10
-
107
-
-
84907983332
-
Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-kappaB signaling pathway
-
Zhang, N.; Chu, E. S.; Zhang, J.; Li, X.; Liang, Q.; Chen, J.; Chen, M.; Teoh, N.; Farrell, G.; Sung, J. J.; et al. Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-kappaB signaling pathway. Oncotarget 2014, 5, 8330-8340.
-
(2014)
Oncotarget
, vol.5
, pp. 8330-8340
-
-
Zhang, N.1
Chu, E.S.2
Zhang, J.3
Li, X.4
Liang, Q.5
Chen, J.6
Chen, M.7
Teoh, N.8
Farrell, G.9
Sung, J.J.10
-
109
-
-
84969972723
-
NRF2 promotes survival following exposure to ionizing radiation
-
in press
-
Sekhar, K. R.; Freeman, M. L. NRF2 promotes survival following exposure to ionizing radiation. Free Radic. Biol. Med. 2015, in press.
-
(2015)
Free Radic. Biol. Med.
-
-
Sekhar, K.R.1
Freeman, M.L.2
-
110
-
-
20144383831
-
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
-
Dinkova-Kostova, A. T.; Liby, K. T.; Stephenson, K. K.; Holtzclaw, W. D.; Gao, X.; Suh, N.; Williams, C.; Risingsong, R.; Honda, T.; Gribble, G. W.; et al. Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress. Proc. Natl. Acad. Sci. USA 2005, 102, 4584-4589.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4584-4589
-
-
Dinkova-Kostova, A.T.1
Liby, K.T.2
Stephenson, K.K.3
Holtzclaw, W.D.4
Gao, X.5
Suh, N.6
Williams, C.7
Risingsong, R.8
Honda, T.9
Gribble, G.W.10
-
111
-
-
0035260034
-
Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione
-
Kwak, M. K.; Itoh, K.; Yamamoto, M.; Sutter, T. R.; Kensler, T. W. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione. Mol. Med. 2001, 7, 135-145.
-
(2001)
Mol. Med.
, vol.7
, pp. 135-145
-
-
Kwak, M.K.1
Itoh, K.2
Yamamoto, M.3
Sutter, T.R.4
Kensler, T.W.5
-
112
-
-
67649637466
-
The expression of NF-E2-related factor 2 in the rat brain after traumatic brain injury
-
Yan, W.; Wang, H. D.; Feng, X. M.; Ding, Y. S.; Jin, W.; Tang, K. The expression of NF-E2-related factor 2 in the rat brain after traumatic brain injury. J. Trauma. 2009, 66, 1431-1435.
-
(2009)
J. Trauma.
, vol.66
, pp. 1431-1435
-
-
Yan, W.1
Wang, H.D.2
Feng, X.M.3
Ding, Y.S.4
Jin, W.5
Tang, K.6
-
113
-
-
34250854714
-
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice
-
Wang, J.; Fields, J.; Zhao, C.; Langer, J.; Thimmulappa, R. K.; Kensler, T. W.; Yamamoto, M.; Biswal, S.; Dore, S. Role of Nrf2 in protection against intracerebral hemorrhage injury in mice. Free Radic. Biol. Med. 2007, 43, 408-414.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 408-414
-
-
Wang, J.1
Fields, J.2
Zhao, C.3
Langer, J.4
Thimmulappa, R.K.5
Kensler, T.W.6
Yamamoto, M.7
Biswal, S.8
Dore, S.9
-
114
-
-
47849083585
-
Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
-
Osburn, W. O.; Kensler, T. W. Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults. Mutat. Res. 2008, 659, 31-39.
-
(2008)
Mutat. Res.
, vol.659
, pp. 31-39
-
-
Osburn, W.O.1
Kensler, T.W.2
-
115
-
-
63549121490
-
NRF2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer
-
Hayes, J. D.; McMahon, M. NRF2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer. Trends Biochem. Sci. 2009, 34, 176-188.
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 176-188
-
-
Hayes, J.D.1
McMahon, M.2
-
116
-
-
33644856080
-
The double-edged sword of Nrf2: Subversion of redox homeostasis during the evolution of cancer
-
Hayes, J. D.; McMahon, M. The double-edged sword of Nrf2: Subversion of redox homeostasis during the evolution of cancer. Mol. Cell 2006, 21, 732-734.
-
(2006)
Mol. Cell
, vol.21
, pp. 732-734
-
-
Hayes, J.D.1
McMahon, M.2
-
117
-
-
74049120454
-
Nrf2: Friend or foe for chemoprevention?
-
Kensler, T. W.; Wakabayashi, N. Nrf2: Friend or foe for chemoprevention? Carcinogenesis 2010, 31, 90-99.
-
(2010)
Carcinogenesis
, vol.31
, pp. 90-99
-
-
Kensler, T.W.1
Wakabayashi, N.2
-
118
-
-
66149168685
-
Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer
-
Homma, S.; Ishii, Y.; Morishima, Y.; Yamadori, T.; Matsuno, Y.; Haraguchi, N.; Kikuchi, N.; Satoh, H.; Sakamoto, T.; Hizawa, N.; et al. Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer. Clin. Cancer Res. 2009, 15, 3423-3432.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 3423-3432
-
-
Homma, S.1
Ishii, Y.2
Morishima, Y.3
Yamadori, T.4
Matsuno, Y.5
Haraguchi, N.6
Kikuchi, N.7
Satoh, H.8
Sakamoto, T.9
Hizawa, N.10
-
119
-
-
84869087891
-
Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers
-
Yamadori, T.; Ishii, Y.; Homma, S.; Morishima, Y.; Kurishima, K.; Itoh, K.; Yamamoto, M.; Minami, Y.; Noguchi, M.; Hizawa, N. Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers. Oncogene 2012, 31, 4768-4777.
-
(2012)
Oncogene
, vol.31
, pp. 4768-4777
-
-
Yamadori, T.1
Ishii, Y.2
Homma, S.3
Morishima, Y.4
Kurishima, K.5
Itoh, K.6
Yamamoto, M.7
Minami, Y.8
Noguchi, M.9
Hizawa, N.10
-
120
-
-
84859496206
-
Combined astaxanthin and fish oil supplementation improves glutathione-based redox balance in rat plasma and neutrophils
-
Barros, M. P.; Marin, D. P.; Bolin, A. P.; de Cassia Santos Macedo, R.; Campoio, T. R.; Fineto, C., Jr.; Guerra, B. A.; Polotow, T. G.; Vardaris, C.; Mattei, R.; et al. Combined astaxanthin and fish oil supplementation improves glutathione-based redox balance in rat plasma and neutrophils. Chem. Biol. Interact. 2012, 197, 58-67.
-
(2012)
Chem. Biol. Interact.
, vol.197
, pp. 58-67
-
-
Barros, M.P.1
Marin, D.P.2
Bolin, A.P.3
De Cassia Santos Macedo, R.4
Campoio, T.R.5
Fineto, C.J.6
Guerra, B.A.7
Polotow, T.G.8
Vardaris, C.9
Mattei, R.10
-
121
-
-
84858965591
-
Cancer chemoprevention by carotenoids
-
Tanaka, T.; Shnimizu, M.; Moriwaki, H. Cancer chemoprevention by carotenoids. Molecules 2012, 17, 3202-3242.
-
(2012)
Molecules
, vol.17
, pp. 3202-3242
-
-
Tanaka, T.1
Shnimizu, M.2
Moriwaki, H.3
-
122
-
-
4344677231
-
Intestinal absorption and metabolism of carotenoids: Insights from cell culture
-
During, A.; Harrison, E. H. Intestinal absorption and metabolism of carotenoids: Insights from cell culture. Arch. Biochem. Biophys. 2004, 430, 77-88.
-
(2004)
Arch. Biochem. Biophys.
, vol.430
, pp. 77-88
-
-
During, A.1
Harrison, E.H.2
-
123
-
-
0035714306
-
Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes
-
Kistler, A.; Liechti, H.; Pichard, L.; Wolz, E.; Oesterhelt, G.; Hayes, A.; Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch. Toxicol. 2002, 75, 665-675.
-
(2002)
Arch. Toxicol.
, vol.75
, pp. 665-675
-
-
Kistler, A.1
Liechti, H.2
Pichard, L.3
Wolz, E.4
Oesterhelt, G.5
Hayes, A.6
Maurel, P.7
-
124
-
-
8844236897
-
Plasma appearance of unesterified astaxanthin geometrical E/Z and optical R/S isomers in men given single doses of a mixture of optical 3 and 3'R/S isomers of astaxanthin fatty acyl diesters
-
Coral-Hinostroza, G. N.; Ytrestoyl, T.; Ruyter, B.; Bjerkeng, B. Plasma appearance of unesterified astaxanthin geometrical E/Z and optical R/S isomers in men given single doses of a mixture of optical 3 and 3'R/S isomers of astaxanthin fatty acyl diesters. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2004, 139, 99-110.
-
(2004)
Comp. Biochem. Physiol. C Toxicol. Pharmacol.
, vol.139
, pp. 99-110
-
-
Coral-Hinostroza, G.N.1
Ytrestoyl, T.2
Ruyter, B.3
Bjerkeng, B.4
-
125
-
-
84857404002
-
Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential
-
Kidd, P. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med. Rev. 2011, 16, 355-364.
-
(2011)
Altern Med. Rev.
, vol.16
, pp. 355-364
-
-
Kidd, P.1
-
127
-
-
84864022325
-
Autophagy in idiopathic pulmonary fibrosis
-
Patel, A. S.; Lin, L.; Geyer, A.; Haspel, J. A.; An, C. H.; Cao, J.; Rosas, I. O.; Morse, D. Autophagy in idiopathic pulmonary fibrosis. PLoS ONE 2012, 7, e41394.
-
(2012)
PLoS ONE
, vol.7
, pp. e41394
-
-
Patel, A.S.1
Lin, L.2
Geyer, A.3
Haspel, J.A.4
An, C.H.5
Cao, J.6
Rosas, I.O.7
Morse, D.8
-
128
-
-
84875915764
-
Autophagy regulates TNFalpha-mediated joint destruction in experimental arthritis
-
Lin, N. Y.; Beyer, C.; Giessl, A.; Kireva, T.; Scholtysek, C.; Uderhardt, S.; Munoz, L. E.; Dees, C.; Distler, A.; Wirtz, S.; et al. Autophagy regulates TNFalpha-mediated joint destruction in experimental arthritis. Ann. Rheum. Dis. 2013, 72, 761-768.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 761-768
-
-
Lin, N.Y.1
Beyer, C.2
Giessl, A.3
Kireva, T.4
Scholtysek, C.5
Uderhardt, S.6
Munoz, L.E.7
Dees, C.8
Distler, A.9
Wirtz, S.10
-
129
-
-
27644466759
-
Autophagy and signaling: Their role in cell survival and cell death
-
Codogno, P.; Meijer, A. J. Autophagy and signaling: Their role in cell survival and cell death. Cell Death Differ. 2005, 12(Suppl. 2), 1509-1518.
-
(2005)
Cell Death Differ.
, vol.12
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
130
-
-
84904755420
-
Mollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways
-
Zhang, L.; Wang, H.; Zhu, J.; Xu, J.; Ding, K. Mollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways. Biochem. Biophys. Res. Commun. 2014, 450, 247-254.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.450
, pp. 247-254
-
-
Zhang, L.1
Wang, H.2
Zhu, J.3
Xu, J.4
Ding, K.5
-
131
-
-
84901798130
-
Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways
-
Zhang, L.; Wang, H.; Xu, J.; Zhu, J.; Ding, K. Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways. Toxicol. Lett. 2014, 228, 248-259.
-
(2014)
Toxicol. Lett.
, vol.228
, pp. 248-259
-
-
Zhang, L.1
Wang, H.2
Xu, J.3
Zhu, J.4
Ding, K.5
-
132
-
-
84899897057
-
Protective effect of astaxanthin on liver fibrosis through modulation of TGF-beta1 expression and autophagy
-
Shen, M.; Chen, K.; Lu, J.; Cheng, P.; Xu, L.; Dai, W.; Wang, F.; He, L.; Zhang, Y.; Chengfen, W.; et al. Protective effect of astaxanthin on liver fibrosis through modulation of TGF-beta1 expression and autophagy. Mediat. Inflamm. 2014, 2014, 954502.
-
(2014)
Mediat. Inflamm.
, vol.2014
, pp. 954502
-
-
Shen, M.1
Chen, K.2
Lu, J.3
Cheng, P.4
Xu, L.5
Dai, W.6
Wang, F.7
He, L.8
Zhang, Y.9
Chengfen, W.10
-
133
-
-
84924362586
-
Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis
-
Li, J.; Xia, Y.; Liu, T.; Wang, J.; Dai, W.; Wang, F.; Zheng, Y.; Chen, K.; Li, S.; Abudumijiti, H.; et al. Protective effects of astaxanthin on ConA-induced autoimmune hepatitis by the JNK/p-JNK pathway-mediated inhibition of autophagy and apoptosis. PLoS ONE 2015, 10, e0120440.
-
(2015)
PLoS ONE
, vol.10
, pp. e0120440
-
-
Li, J.1
Xia, Y.2
Liu, T.3
Wang, J.4
Dai, W.5
Wang, F.6
Zheng, Y.7
Chen, K.8
Li, S.9
Abudumijiti, H.10
-
134
-
-
0033608747
-
Science, medicine, and the future. Antivascular therapy: A new approach to cancer treatment
-
Hayes, A. J.; Li, L. Y.; Lippman, M. E. Science, medicine, and the future. Antivascular therapy: A new approach to cancer treatment. BMJ 1999, 318, 853-856.
-
(1999)
BMJ
, vol.318
, pp. 853-856
-
-
Hayes, A.J.1
Li, L.Y.2
Lippman, M.E.3
-
135
-
-
33646557055
-
Angiogenesis-A new target for future therapy
-
Pandya, N. M.; Dhalla, N. S.; Santani, D. D. Angiogenesis-A new target for future therapy. Vasc. Pharmacol. 2006, 44, 265-274.
-
(2006)
Vasc. Pharmacol.
, vol.44
, pp. 265-274
-
-
Pandya, N.M.1
Dhalla, N.S.2
Santani, D.D.3
-
136
-
-
84938268152
-
microRNA-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14
-
Li, Y.; Kuscu, C.; Banach, A.; Zhang, Q.; Pulkoski-Gross, A.; Kim, D.; Liu, J.; Roth, E.; Li, E.; Shroyer, K. R.; et al. microRNA-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14. Cancer Res. 2015, 75, 2674-2685.
-
(2015)
Cancer Res.
, vol.75
, pp. 2674-2685
-
-
Li, Y.1
Kuscu, C.2
Banach, A.3
Zhang, Q.4
Pulkoski-Gross, A.5
Kim, D.6
Liu, J.7
Roth, E.8
Li, E.9
Shroyer, K.R.10
-
137
-
-
84926430176
-
Cancer prevention and therapy through the modulation of the tumor microenvironment
-
in press
-
Casey, S. C.; Amedei, A.; Aquilano, K.; Azmi, A. S.; Benencia, F.; Bhakta, D.; Bilsland, A. E.; Boosani, C. S.; Chen, S.; Ciriolo, M. R.; et al. Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin. Cancer Biol. 2015, in press.
-
(2015)
Semin. Cancer Biol.
-
-
Casey, S.C.1
Amedei, A.2
Aquilano, K.3
Azmi, A.S.4
Benencia, F.5
Bhakta, D.6
Bilsland, A.E.7
Boosani, C.S.8
Chen, S.9
Ciriolo, M.R.10
-
138
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh, J. J.; Desjardins, A.; Herndon, J. E., 2nd; Dowell, J. M.; Reardon, D. A.; Quinn, J. A.; Rich, J. N.; Sathornsumetee, S.; Gururangan, S.; et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin. Cancer Res. 2007, 13, 1253-1259.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon, J.E.3
Dowell, J.M.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
|