Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway

Immunopharmacology and Immunotoxicology

Volumn 37, Issue 3, 2015, Pages 265-273

  Baek, Seung Ho ^a   Kim, Chulwon ^a   Lee, Jong Hyun ^a   Nam, Dongwoo ^a   Lee, Junhee ^a   Lee, Seok Geun ^a   Chung, Won Seok ^a   Jang, Hyeung Jin ^a   Kim, Sung Hoon ^a   Ahn, Kwang Seok ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Apoptosis; Cinobufagin; MAPKs; Multiple myeloma; ROS

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CINOBUFAGIN; CYCLIN D1; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SURVIVIN; VASCULOTROPIN; BUFADIENOLIDE DERIVATIVE;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA CONTENT; DNA REPAIR; DOWN REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; METASTASIS; MITOCHONDRION; MULTIPLE MYELOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; APOPTOSIS; CELL LINE; DRUG EFFECTS; IMMUNOLOGY; PATHOLOGY;

ANURA; BUFO GARGARIZANS;

APOPTOSIS; BUFANOLIDES; CELL LINE; CELL PROLIFERATION; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 84931047328     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2015.1027916     Document Type: Article

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