Astaxanthin activates nuclear factor erythroid-related factor 2 and the antioxidant responsive element (nrf2-are) pathway in the brain after subarachnoid hemorrhage in rats and attenuates early brain injury

Marine Drugs

Volumn 12, Issue 12, 2014, Pages 6125-6141

  Wu, Qi ^a   Zhang, Xiang Sheng ^a   Wang, Han Dong ^a   Zhang, Xin ^a   Yu, Qing ^b   Li, Wei ^a   Zhou, Meng Liang ^a   Wang, Xiao Liang ^a  

^a NANJING UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Astaxanthin; Early brain injury; Nuclear factor erythroid related factor 2; Subarachnoid hemorrhage

Indexed keywords

ASTAXANTHIN; GLUTATHIONE TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE ALPHA 1; HEME OXYGENASE 1; MALONALDEHYDE; MESSENGER RNA; NAD(P)H:QUINONE OXIDOREDUCTASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; GLUTATHIONE S-TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE; ISOENZYME; NFE2L2 PROTEIN, RAT; NQO1 PROTEIN, HUMAN; XANTHOPHYLL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN EDEMA; BRAIN INJURY; BRAIN WATER; CONTROLLED STUDY; DRUG MECHANISM; EARLY BRAIN INJURY; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MALE; MENTAL PERFORMANCE; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; SUBARACHNOID HEMORRHAGE; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN; BRAIN INJURIES; DISEASE MODEL; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; GLUTATHIONE TRANSFERASE; HEME OXYGENASE-1; ISOENZYMES; MALE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; XANTHOPHYLLS;

EID: 84919904588     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12126125     Document Type: Article

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