Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism

Brain Research

Volumn 1254, Issue , 2009, Pages 18-27

  Liu, Xuebo ^a   Shibata, Takahiro ^a   Hisaka, Shinsuke ^a   Osawa, Toshihiko ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Astaxanthin; Mitochondria protection; Neuronal apoptosis; Parkinson's disease; Reactive oxygen specie

Indexed keywords

ANTIOXIDANT; ASTAXANTHIN; CYTOCHROME C; DOCOSAHEXAENOIC ACID; DOCOSAHEXAENOIC ACID HYDROPEROXIDE; DOPAMINE; LIPID PEROXIDE; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; XANTHOPHYLL;

APOPTOSIS; ARTICLE; CELL LINE; CELL SURVIVAL; DNA FRAGMENTATION; DRUG EFFECT; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVE CELL; PHYSIOLOGY; PROTEIN CARBONYLATION; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROMES C; DNA FRAGMENTATION; DOCOSAHEXAENOIC ACIDS; DOPAMINE; HUMANS; LIPID PEROXIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NEURONS; OXIDOPAMINE; PROTEIN CARBONYLATION; REACTIVE OXYGEN SPECIES; XANTHOPHYLLS;

EID: 58549103079     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.11.076     Document Type: Article

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