메뉴 건너뛰기




Volumn 9, Issue 10, 2012, Pages 561-570

Aspirin as adjuvant therapy for colorectal cancer - Reinterpreting paradigms

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 2; IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; ROFECOXIB; TUMOR MARKER;

EID: 84867101876     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2012.137     Document Type: Review
Times cited : (92)

References (112)
  • 2
    • 0023855192 scopus 로고
    • Postoperative adjuvant chemotherapy or BCG for colon cancer: Results from NSABP protocol C-01
    • Wolmark, N. et al. Postoperative adjuvant chemotherapy or BCG for colon cancer: results from NSABP protocol C-01. J. Natl Cancer Inst. 80, 30-36 (1988).
    • (1988) J. Natl Cancer Inst. , vol.80 , pp. 30-36
    • Wolmark, N.1
  • 3
    • 0028956045 scopus 로고
    • Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
    • Moertel, C. G. et al. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann. Intern. Med. 122, 321-226 (1995).
    • (1995) Ann. Intern. Med. , vol.122 , pp. 321-226
    • Moertel, C.G.1
  • 4
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
    • O'Connell, M. J. et al. Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J. Clin. Oncol. 15, 246-250 (1997).
    • (1997) J. Clin. Oncol. , vol.15 , pp. 246-250
    • O'Connell, M.J.1
  • 5
    • 15744377355 scopus 로고    scopus 로고
    • Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer
    • Poplin, E. A. et al. Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer. J. Clin. Oncol. 23, 1819-1825 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 1819-1825
    • Poplin, E.A.1
  • 6
    • 20944436646 scopus 로고    scopus 로고
    • A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer
    • Chau, I. et al. A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer. Ann. Oncol. 16, 549-557 (2005).
    • (2005) Ann. Oncol. , vol.16 , pp. 549-557
    • Chau, I.1
  • 7
    • 21244497388 scopus 로고    scopus 로고
    • Capecitabine as adjuvant treatment for stage III colon cancer
    • Twelves, C. et al. Capecitabine as adjuvant treatment for stage III colon cancer. N. Engl. J. Med. 352, 2696-2704 (2005).
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2696-2704
    • Twelves, C.1
  • 8
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • Andre, T. et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N. Engl. J. Med. 350, 2343-2351 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2343-2351
    • Andre, T.1
  • 9
    • 67650290547 scopus 로고    scopus 로고
    • Randomized phase III trial comparing biweekly infusional flurouracilleucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer. PETACC-3
    • Van Cutsem, E. et al. Randomized phase III trial comparing biweekly infusional flurouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer. PETACC-3. J. Clin. Oncol. 27, 3117-3125 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 3117-3125
    • Van Cutsem, E.1
  • 10
    • 63549145899 scopus 로고    scopus 로고
    • A phase III randomized trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802)
    • Ychou, M. et al. A phase III randomized trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802). Ann. Oncol. 20, 674-680 (2009).
    • (2009) Ann. Oncol. , vol.20 , pp. 674-680
    • Ychou, M.1
  • 11
    • 34548160680 scopus 로고    scopus 로고
    • Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: Results of CALGB 89803
    • Saltz, L. B. et al. Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J. Clin. Oncol. 25, 3456-3461 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 3456-3461
    • Saltz, L.B.1
  • 12
    • 33748583563 scopus 로고    scopus 로고
    • Adjuvant chemotherapy for colon cancer -what, when and how
    • Chau, I. & Cunningham, D. Adjuvant chemotherapy for colon cancer -what, when and how. Ann. Oncol. 9, 1347-1359 (2006).
    • (2006) Ann. Oncol. , vol.9 , pp. 1347-1359
    • Chau, I.1    Cunningham, D.2
  • 13
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz, H. et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350, 2335-2342 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1
  • 14
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz, L. B. et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J. Clin. Oncol. 26, 2013-2019 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2013-2019
    • Saltz, L.B.1
  • 15
    • 0037967272 scopus 로고    scopus 로고
    • Angiogenesis: Tumorigenesis and the angiogenic switch
    • Bergers, G. & Benjamin, L. E. Angiogenesis: Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3, 401-410 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 16
    • 27944435391 scopus 로고    scopus 로고
    • The future development of bevacizumab in colorectal cancer
    • Diaz-Rubio, E. & Schmoll, H. J. The future development of bevacizumab in colorectal cancer. Oncology 69 (S3), 34-45 (2005).
    • (2005) Oncology , vol.69 , Issue.S3 , pp. 34-45
    • Diaz-Rubio, E.1    Schmoll, H.J.2
  • 17
    • 79551521053 scopus 로고    scopus 로고
    • Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: Results of NSABP protocol C-08
    • Allegra, C. J. et al. Phase III trial assessing bevacizumab in stages II and III carcinoma of the colon: results of NSABP protocol C-08. J. Clin. Oncol. 29, 11-16 (2011).
    • (2011) J. Clin. Oncol. 29 , pp. 11-16
    • Allegra, C.J.1
  • 18
    • 79953236184 scopus 로고    scopus 로고
    • AVANT: Results from a randomized three-arm multinational phase III study to investigate bevacizumab with either XELOX or FOLFOX4 versus FOLFOX4 alone as adjuvant treatment for colon cancer [abstract]
    • De Gramont, A. et al. AVANT: Results from a randomized, three-arm multinational phase III study to investigate bevacizumab with either XELOX or FOLFOX4 versus FOLFOX4 alone as adjuvant treatment for colon cancer [abstract]. J. Clin. Oncol. 29 (Suppl. 4), a362 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.SUPPL. 4
    • De Gramont, A.1
  • 19
    • 84859403854 scopus 로고    scopus 로고
    • Effect of oxaliplatin, flurouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: A randomized trial
    • Alberts, S. R. et al. Effect of oxaliplatin, flurouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. JAMA 307, 1383-1393 (2012).
    • (2012) JAMA , vol.307 , pp. 1383-1393
    • Alberts, S.R.1
  • 21
    • 34247347310 scopus 로고    scopus 로고
    • Influence of regular aspirin use on survival for patients with stage III colon cancer: Findings from intergroup trial CALGB 89803 [abstract]
    • Fuchs, C. S. et al. Influence of regular aspirin use on survival for patients with stage III colon cancer: findings from intergroup trial CALGB 89803 [abstract]. J. Clin. Oncol. 23 (Suppl. 16), a3530 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , Issue.SUPPL. 16
    • Fuchs, C.S.1
  • 22
    • 68849123400 scopus 로고    scopus 로고
    • Aspirin use and survival after diagnosis of colorectal cancer
    • Chan, A. T., Ogino, S. & Fuchs, C. S. Aspirin use and survival after diagnosis of colorectal cancer. JAMA 302, 649-659 (2009).
    • (2009) JAMA , vol.302 , pp. 649-659
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 23
    • 73149089476 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs: Effects on mortality after colorectal cancer diagnosis
    • Zell, J. A. et al. Non-steroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis. Cancer 115, 5662-5671 (2009).
    • (2009) Cancer , vol.115 , pp. 5662-5671
    • Zell, J.A.1
  • 24
    • 79952533784 scopus 로고    scopus 로고
    • Pre-diagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer
    • Coghill, A. E. et al. Pre-diagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer. Gut 60, 491-498 (2011).
    • (2011) Gut , vol.60 , pp. 491-498
    • Coghill, A.E.1
  • 25
    • 84860250352 scopus 로고    scopus 로고
    • Use of aspirin postdiagnosis improves survival for colon cancer patients
    • Bastiaannet, E. et al. Use of aspirin postdiagnosis improves survival for colon cancer patients. Br. J. Cancer 106, 1564-1570 (2012).
    • (2012) Br. J. Cancer , vol.106 , pp. 1564-1570
    • Bastiaannet, E.1
  • 26
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: A study of incident cancers during randomised controlled trials
    • Rothwell, P. et al. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet 379, 1591-1601 (2012).
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.1
  • 27
    • 83355163988 scopus 로고    scopus 로고
    • The utility of aspirin in Dukes C and high risk Dukes B colorectal cancer - The ASCOLT study: Study protocol for a randomized controlled trial
    • Ali, R., Toh, H. C. & Chia, W. K. The utility of aspirin in Dukes C and high risk Dukes B colorectal cancer -the ASCOLT study: study protocol for a randomized controlled trial. Trials 12, 261 (2011).
    • (2011) Trials , vol.12 , pp. 261
    • Ali, R.1    Toh, H.C.2    Chia, W.K.3
  • 28
    • 84875254905 scopus 로고    scopus 로고
    • US National Library Of Medicine
    • US National Library of Medicine. Clinicaltrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT01150045 (2012).
    • (2012)
  • 29
    • 0037421984 scopus 로고    scopus 로고
    • A randomised trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer
    • Sandler, R. S. et al. A randomised trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N. Engl. J. Med. 348, 883-890 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 883-890
    • Sandler, R.S.1
  • 30
    • 0037421985 scopus 로고    scopus 로고
    • A randomised trial of aspirin to prevent colorectal adenomas
    • Baron, J. A. et al. A randomised trial of aspirin to prevent colorectal adenomas. N. Engl. J. Med. 348, 891-899 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 891-899
    • Baron, J.A.1
  • 31
    • 37349129228 scopus 로고    scopus 로고
    • Aspirin and folic acid for the prevention of recurrent colorectal adenomas
    • Logan, R. F. et al. Aspirin and folic acid for the prevention of recurrent colorectal adenomas. Gastroenterology 134, 29-38 (2008).
    • (2008) Gastroenterology , vol.134 , pp. 29-38
    • Logan, R.F.1
  • 32
    • 0042031492 scopus 로고    scopus 로고
    • Daily soluble aspirin and prevention of colorectal adenoma recurrence: One-year results of the APACC trial
    • Benamouzig, R. et al. Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial. Gastroenterology 125, 328-336 (2003).
    • (2003) Gastroenterology , vol.125 , pp. 328-336
    • Benamouzig, R.1
  • 33
    • 33748196958 scopus 로고    scopus 로고
    • Celecoxib for the prevention of sporadic colorectal adenomas
    • Bertagnolli, M. M. et al. Celecoxib for the prevention of sporadic colorectal adenomas. N. Engl. J. Med. 355, 873-884 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 873-884
    • Bertagnolli, M.M.1
  • 34
    • 33748180713 scopus 로고    scopus 로고
    • Celecoxib for the prevention of colorectal adenomatous polyps
    • Arber, N. et al. Celecoxib for the prevention of colorectal adenomatous polyps. N. Engl. J. Med. 355, 885-895 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 885-895
    • Arber, N.1
  • 35
    • 33845288081 scopus 로고    scopus 로고
    • A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas
    • Baron, J. A. et al. A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology 131, 1674-1682 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 1674-1682
    • Baron, J.A.1
  • 36
    • 55549132996 scopus 로고    scopus 로고
    • Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: A randomized placebo-controlled, double-blind trial
    • Meyskens, F. L. et al. Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial. Cancer Prev. Res. 1, 32-38 (2008).
    • (2008) Cancer Prev. Res. , vol.1 , pp. 32-38
    • Meyskens, F.L.1
  • 37
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • Giardiello, F. M. et al. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med. 328, 1313-1316 (1993).
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1313-1316
    • Giardiello, F.M.1
  • 38
    • 0025834849 scopus 로고
    • Sulindac causes regression of rectal polyps in familial adenomatous polyposis
    • Labayle, D. et al. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology 101, 635-639 (1991).
    • (1991) Gastroenterology , vol.101 , pp. 635-639
    • Labayle, D.1
  • 39
    • 17744418769 scopus 로고    scopus 로고
    • The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
    • Steinbach, G. et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N. Engl. J. Med. 342, 1946-1952 (2000).
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1946-1952
    • Steinbach, G.1
  • 40
    • 0242486770 scopus 로고    scopus 로고
    • Rofecoxib reduces polyp recurrences in familial polyposis
    • Hallak, A. et al. Rofecoxib reduces polyp recurrences in familial polyposis. Dig. Dis. Sci. 48, 1998-2002 (2003).
    • (2003) Dig. Dis. Sci. , vol.48 , pp. 1998-2002
    • Hallak, A.1
  • 41
    • 83955161674 scopus 로고    scopus 로고
    • The long-term impact of aspirin on cancer risk in carriers of hereditary colorectal cancer: The CAPP2 randomized control trial
    • Burn, J. et al. The long-term impact of aspirin on cancer risk in carriers of hereditary colorectal cancer: the CAPP2 randomized control trial. Lancet 378, 2081-2087 (2011).
    • (2011) Lancet , vol.378 , pp. 2081-2087
    • Burn, J.1
  • 42
    • 0027512524 scopus 로고
    • Aspirin use and risk of fatal cancer
    • Thun, M. J. et al. Aspirin use and risk of fatal cancer. Cancer Res. 53, 1322-1327 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 1322-1327
    • Thun, M.J.1
  • 43
    • 37349041679 scopus 로고    scopus 로고
    • Aspirin dose and duration of use and the risk of colorectal cancer in men
    • Chan, A. T. et al. Aspirin dose and duration of use and the risk of colorectal cancer in men. Gastroenterology 134, 21-28 (2008).
    • (2008) Gastroenterology , vol.134 , pp. 21-28
    • Chan, A.T.1
  • 44
    • 23944436934 scopus 로고    scopus 로고
    • Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer
    • Chan, A. T. et al. Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA 294, 914-923 (2005).
    • (2005) JAMA , vol.294 , pp. 914-923
    • Chan, A.T.1
  • 45
    • 0028325496 scopus 로고
    • Aspirin use and lung, colon, and breast cancer incidence in a prospective study
    • Schreinemachers, D. M. & Everson, R. B. Aspirin use and lung, colon, and breast cancer incidence in a prospective study. Epidemiology 5, 138-146 (1994).
    • (1994) Epidemiology , vol.5 , pp. 138-146
    • Schreinemachers, D.M.1    Everson, R.B.2
  • 46
    • 0029150934 scopus 로고
    • Aspirin and the risk of colorectal cancer in women
    • Giovannucci, E. et al. Aspirin and the risk of colorectal cancer in women. N. Engl. J. Med. 333, 609-614 (1995).
    • (1995) N. Engl. J. Med. , vol.333 , pp. 609-614
    • Giovannucci, E.1
  • 47
    • 0037422004 scopus 로고    scopus 로고
    • Aspirin and the prevention of colorectal cancer
    • Impreriale, T. F. Aspirin and the prevention of colorectal cancer. N. Engl. J. Med. 348, 879-880 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 879-880
    • Impreriale, T.F.1
  • 48
    • 34248157118 scopus 로고    scopus 로고
    • Effect of aspirin on long-term risk of colorectal cancer: Consistent evidence from randomised and observational studies
    • Flossmann, E. & Rothwell, P. M. Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet 369, 1603-1613 (2007).
    • (2007) Lancet , vol.369 , pp. 1603-1613
    • Flossmann, E.1    Rothwell, P.M.2
  • 49
    • 78650215449 scopus 로고    scopus 로고
    • Long-term effect of aspirin on colorectal cancer incidence and mortality: 20 year follow-up of five randomised trials
    • Rothwell, P. M. et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20 year follow-up of five randomised trials. Lancet 376, 1741-1750 (2010).
    • (2010) Lancet , vol.376 , pp. 1741-1750
    • Rothwell, P.M.1
  • 50
    • 78650825618 scopus 로고    scopus 로고
    • Effect of aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
    • Rothwell, P. M. et al. Effect of aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 377, 31-41 (2011).
    • (2011) Lancet , vol.377 , pp. 31-41
    • Rothwell, P.M.1
  • 51
    • 84863412124 scopus 로고    scopus 로고
    • Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: Analysis of the time course of risks and benefits in 51 randomised controlled trials
    • Rothwell, P. M. et al. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet 379, 1602-1612 (2012).
    • (2012) Lancet , vol.379 , pp. 1602-1612
    • Rothwell, P.M.1
  • 52
    • 84858766331 scopus 로고    scopus 로고
    • New data on aspirin and colorectal cancer brings calls for new guidelines, more research
    • McNeal, C. New data on aspirin and colorectal cancer brings calls for new guidelines, more research. J. Natl Cancer Inst. 104, 172-174 (2012).
    • (2012) J. Natl Cancer Inst. , vol.104 , pp. 172-174
    • McNeal, C.1
  • 53
    • 0025748695 scopus 로고
    • A randomized prospective assessment of recombinant leukocyte A human interferon with or without aspirin in advanced renal adenocarcinoma
    • Creagan, E. T. et al. A randomized prospective assessment of recombinant leukocyte A human interferon with or without aspirin in advanced renal adenocarcinoma. J. Clin. Oncol. 9, 2104-2109 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , pp. 2104-2109
    • Creagan, E.T.1
  • 54
    • 0027403212 scopus 로고
    • No effect of an antiaggregant treatment with aspirin in small cell lung cancer treated with CCAVP16 chemotherapy. Results from a randomiszed clinical trial of 303 patients
    • Lebeau, B. et al. No effect of an antiaggregant treatment with aspirin in small cell lung cancer treated with CCAVP16 chemotherapy. Results from a randomiszed clinical trial of 303 patients. Cancer 71, 1741-1745 (1993).
    • (1993) Cancer , vol.71 , pp. 1741-1745
    • Lebeau, B.1
  • 55
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • Shoemaker, R. H. The NCI60 human tumour cell line anticancer drug screen. Nat. Rev. Cancer 6, 813-823 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 813-823
    • Shoemaker, R.H.1
  • 56
    • 79961016292 scopus 로고    scopus 로고
    • From chemotherapy to targeted therapy in adjuvant treatment for stage III colon cancer
    • De Gramont, A. et al. From chemotherapy to targeted therapy in adjuvant treatment for stage III colon cancer. Semin. Oncol. 38, 521-532 (2011).
    • (2011) Semin. Oncol. , vol.38 , pp. 521-532
    • De Gramont, A.1
  • 57
    • 80052709329 scopus 로고    scopus 로고
    • Predictive factors for pulmonary metastasis after curative resection of rectal cancer without preoperative chemoradiotherapy
    • Watanabe, K. et al. Predictive factors for pulmonary metastasis after curative resection of rectal cancer without preoperative chemoradiotherapy. Dis. Colon Rectum 54, 989-998 (2011).
    • (2011) Dis. Colon Rectum , vol.54 , pp. 989-998
    • Watanabe, K.1
  • 58
    • 77956808352 scopus 로고    scopus 로고
    • Inguinal lymph node metastases are recognized with high frequency in rectal adenocarcinoma invading the dentate line. The histological features at the invasive front may predict inguinal lymph node metastasis
    • Hamano, T. et al. Inguinal lymph node metastases are recognized with high frequency in rectal adenocarcinoma invading the dentate line. The histological features at the invasive front may predict inguinal lymph node metastasis. Colorectal Dis. 10, e200-e205 (2010).
    • (2010) Colorectal Dis. , vol.10
    • Hamano, T.1
  • 59
    • 33846853995 scopus 로고    scopus 로고
    • Mesorectal grades predict recurrences after curative resection for rectal cancer
    • Maslekar, S. et al. Mesorectal grades predict recurrences after curative resection for rectal cancer. Dis. Colon Rectum 50, 168-175 (2007).
    • (2007) Dis. Colon Rectum , vol.50 , pp. 168-175
    • Maslekar, S.1
  • 60
    • 18544366219 scopus 로고    scopus 로고
    • Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in the Netherlands
    • Kapiteijn, E. et al. Impact of the introduction and training of total mesorectal excision on recurrence and survival in rectal cancer in The Netherlands. Br. J. Surg. 89, 1142-1149 (2002).
    • (2002) Br. J. Surg. , vol.89 , pp. 1142-1149
    • Kapiteijn, E.1
  • 61
    • 84860589077 scopus 로고    scopus 로고
    • Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum
    • Yamauchi, M. et al. Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum. Gut 61, 847-854 (2012).
    • (2012) Gut , vol.61 , pp. 847-854
    • Yamauchi, M.1
  • 62
    • 84860599697 scopus 로고    scopus 로고
    • Colorectal cancer: A tale of two sides or a continuum?
    • Yamauchi, M. et al. Colorectal cancer: a tale of two sides or a continuum? Gut 61, 794-797 (2012).
    • (2012) Gut , vol.61 , pp. 794-797
    • Yamauchi, M.1
  • 63
    • 79952191728 scopus 로고    scopus 로고
    • Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer
    • Wong, J. J. L. et al. Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer. Mod. Pathol. 24, 396-411 (2011).
    • (2011) Mod. Pathol. , vol.24 , pp. 396-411
    • Wong, J.J.L.1
  • 65
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • Ogino, S. & Goel, A. Molecular classification and correlates in colorectal cancer. J. Mol. Diagn. 10, 13-27 (2008).
    • (2008) J. Mol. Diagn. , vol.10 , pp. 13-27
    • Ogino, S.1    Goel, A.2
  • 66
    • 80052929478 scopus 로고    scopus 로고
    • CpG island methylation in colorectal cancer: Past, present and future
    • Curtin, K., Slattery, M. L. & Samowitz, W. S. CpG island methylation in colorectal cancer: past, present and future. Pathol. Res. Int. 2011, 902674 (2011).
    • (2011) Pathol. Res. Int. , vol.2011 , pp. 902674
    • Curtin, K.1    Slattery, M.L.2    Samowitz, W.S.3
  • 67
    • 81255179895 scopus 로고    scopus 로고
    • The CpG island methylator phenotype in colorectal cancer: Progress and problems
    • Hughes, L. A. E. et al. The CpG island methylator phenotype in colorectal cancer: Progress and problems. Biochim. Biophys. Acta 1825, 77-85 (2012).
    • (2012) Biochim. Biophys. Acta , vol.1825 , pp. 77-85
    • Hughes, L.A.E.1
  • 68
    • 33750516680 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and subsite-specific colorectal cancer incidence in the Iowa women's health study
    • Mahipal, A. et al. Nonsteroidal anti-inflammatory drugs and subsite-specific colorectal cancer incidence in the Iowa women's health study. Cancer Epidemiol. Biomarkers Prev. 15, 1785-1790 (2006).
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 1785-1790
    • Mahipal, A.1
  • 69
    • 84875264170 scopus 로고
    • A Hypothesis: Nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer
    • Rosenberg, L. et al. A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer. J. Natl Cancer Inst. 159, 161-166 (1991).
    • (1991) J. Natl Cancer Inst. , vol.159 , pp. 161-166
    • Rosenberg, L.1
  • 70
    • 37649002657 scopus 로고    scopus 로고
    • Low-dose aspirin in patients with stable cardiovascular disease: A meta-analysis
    • Berger, J. S., Brown, D. L. & Becker, R. C. Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis. Am. J. Med. 121, 43-49 (2008).
    • (2008) Am. J. Med. , vol.121 , pp. 43-49
    • Berger, J.S.1    Brown, D.L.2    Becker, R.C.3
  • 71
    • 0028299690 scopus 로고
    • Selection bias in observational and experimental studies
    • Ellenberg, J. H. Selection bias in observational and experimental studies. Stat. Med. 13, 557-567 (1994).
    • (1994) Stat. Med. , vol.13 , pp. 557-567
    • Ellenberg, J.H.1
  • 72
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • Chan, A. T., Ogino, S. & Fuchs, C. S. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N. Engl. J. Med. 356, 2131-2142 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 73
    • 58149340659 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer
    • Ogino, S. et al. Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer. Clin. Cancer Res. 14, 8221-8227 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 8221-8227
    • Ogino, S.1
  • 74
    • 11144224065 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer
    • Soumaoro, L. T. et al. Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer. Clin. Cancer Res. 10, 8465-8471 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8465-8471
    • Soumaoro, L.T.1
  • 75
    • 78049523725 scopus 로고    scopus 로고
    • Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: Final results of the VICTOR Trial
    • Midgley, R. S. et al. Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR Trial. J. Clin. Oncol. 28, 4575-4580 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4575-4580
    • Midgley, R.S.1
  • 76
    • 33746448278 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials
    • McQuaid, K. R. & Laine, L. Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials. Am. J. Med. 119, 624-638 (2006).
    • (2006) Am. J. Med. , vol.119 , pp. 624-638
    • McQuaid, K.R.1    Laine, L.2
  • 77
    • 79959345305 scopus 로고    scopus 로고
    • Effect of aspirin on mortality in the primary prevention of cardiovascular disease
    • Raju, N. et al. Effect of aspirin on mortality in the primary prevention of cardiovascular disease. Am. J. Med. 124, 621-629 (2011).
    • (2011) Am. J. Med. , vol.124 , pp. 621-629
    • Raju, N.1
  • 78
    • 0034638656 scopus 로고    scopus 로고
    • Risk of gastrointestinal haemorrhage with long term use of aspirin: Meta-analysis
    • Derry, S. & Loke, Y. K. Risk of gastrointestinal haemorrhage with long term use of aspirin: meta-analysis. BMJ 321, 1183-1187 (2000).
    • (2000) BMJ , vol.321 , pp. 1183-1187
    • Derry, S.1    Loke, Y.K.2
  • 79
    • 84857376799 scopus 로고    scopus 로고
    • Effect of aspirin on vascular and nonvascular outcomes: Meta-analysis of randomized controlled trials
    • Seshasai, S. R. et al. Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials. Arch. Intern. Med. 172, 209-216 (2012).
    • (2012) Arch. Intern. Med. , vol.172 , pp. 209-216
    • Seshasai, S.R.1
  • 80
    • 33748316476 scopus 로고    scopus 로고
    • Review article: Gastrointestinal bleeding with low-dose aspirin -what's the risk?
    • Laine, L. Review article: gastrointestinal bleeding with low-dose aspirin -what's the risk? Aliment. Pharmacol. Ther. 24, 897-908 (2006).
    • (2006) Aliment. Pharmacol. Ther. , vol.24 , pp. 897-908
    • Laine, L.1
  • 81
    • 79960200973 scopus 로고    scopus 로고
    • Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: A meta-analysis of randomized trials
    • Berger, J. S., Lala, A., Krantz, M. J., Baker, G. S. & Hiatt, W. R. Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: A meta-analysis of randomized trials. Am. Heart J. 162, 115-124 (2011).
    • (2011) Am. Heart J. , vol.162 , pp. 115-124
    • Berger, J.S.1    Lala, A.2    Krantz, M.J.3    Baker, G.S.4    Hiatt, W.R.5
  • 82
    • 80052026195 scopus 로고    scopus 로고
    • Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis
    • Lanas, A., Wu, P., Medin, J. & Mills, E. J. Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis. Clin. Gastroenterol. Hepatol. 9, 762-768 (2011).
    • (2011) Clin. Gastroenterol. Hepatol. , vol.9 , pp. 762-768
    • Lanas, A.1    Wu, P.2    Medin, J.3    Mills, E.J.4
  • 83
    • 0030851487 scopus 로고    scopus 로고
    • Supression of human colorectal mucosal prostaglandins: Determining the lowest effective aspirin dose
    • Ruffin, M. T. et al. Supression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose. J. Natl Cancer Inst. 89, 1152-1160 (1997).
    • (1997) J. Natl Cancer Inst. , vol.89 , pp. 1152-1160
    • Ruffin, M.T.1
  • 84
    • 0036227319 scopus 로고    scopus 로고
    • A dose-finding study of aspirin for chemoprevention utilizing rectal mucosal prostaglandin E(2) levels as a biomarker
    • Sample, D. et al. A dose-finding study of aspirin for chemoprevention utilizing rectal mucosal prostaglandin E(2) levels as a biomarker. Cancer Epidemiol. Biomarkers Prev. 11, 275-279 (2002).
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 275-279
    • Sample, D.1
  • 85
    • 0024406369 scopus 로고
    • Final report on the aspirin component of the ongoing physicians' health study. Steering committee of the physicians' health study research group
    • [No Authors Listed]
    • [No authors listed] Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group. N. Engl. J. Med. 321, 129-135 (1989).
    • (1989) N. Engl. J. Med. , vol.321 , pp. 129-135
  • 86
    • 21444450527 scopus 로고    scopus 로고
    • Low-dose aspirin in the primary prevention of cancer: The Women's Health Study: A randomized controlled trial
    • Cook, N. R. et al. Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA 294, 47-55 (2005).
    • (2005) JAMA , vol.294 , pp. 47-55
    • Cook, N.R.1
  • 87
    • 51449124055 scopus 로고    scopus 로고
    • Cardiovascular and gastrointestinal toxicity of selective cyclooxygenase-2 inhibitors in man
    • Dajani, E. Z. & Islam, K. Cardiovascular and gastrointestinal toxicity of selective cyclooxygenase-2 inhibitors in man. J. Physiol. Pharmacol. 59 (Suppl. 2), 117-133 (2008).
    • (2008) J. Physiol. Pharmacol. , vol.59 , Issue.SUPPL. 2 , pp. 117-133
    • Dajani, E.Z.1    Islam, K.2
  • 88
    • 33645841057 scopus 로고    scopus 로고
    • International comparisons of cumulative risk of colorectal cancer, from cancer incidence in five continents Vol. VIII
    • Tanaka, S. & Imamura, Y. International Comparisons of Cumulative Risk of Colorectal Cancer, from Cancer Incidence in Five Continents Vol. VIII. Jpn J. Clin. Oncol. 36, 186-187 (2006).
    • (2006) Jpn J. Clin. Oncol. , vol.36 , pp. 186-187
    • Tanaka, S.1    Imamura, Y.2
  • 89
    • 82955212867 scopus 로고    scopus 로고
    • COX-2 expression predicts worse breast cancer prognosis and does not modify association with aspirin
    • Holmes, M. D. et al. COX-2 expression predicts worse breast cancer prognosis and does not modify association with aspirin. Breast Cancer Res. 130, 657-662 (2011).
    • (2011) Breast Cancer Res , vol.130 , pp. 657-662
    • Holmes, M.D.1
  • 90
    • 79851511414 scopus 로고    scopus 로고
    • Molecular pathologic epidemiology of colorectal neoplasia: An emerging transdisciplinary and interdisciplinary field
    • Ogino, S., Chan, A. T., Fuchs, C. S. & Giovannucci, E. Molecular pathologic epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut 60, 397-411 (2011).
    • (2011) Gut , vol.60 , pp. 397-411
    • Ogino, S.1    Chan, A.T.2    Fuchs, C.S.3    Giovannucci, E.4
  • 91
    • 77949928737 scopus 로고    scopus 로고
    • Lifestyle factors and microsatellite instability in colorectal cancer: The evolving field of molecular pathological epidemiology
    • Ogino, S. & Stampfer, M. Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology. J. Natl Cancer Inst. 102, 365-366 (2010).
    • (2010) J. Natl Cancer Inst. , vol.102 , pp. 365-366
    • Ogino, S.1    Stampfer, M.2
  • 92
    • 79959745909 scopus 로고    scopus 로고
    • A strategy for distinguishing optimal cancer subtypes
    • Begg, C. B. A strategy for distinguishing optimal cancer subtypes. Int. J. Cancer 129, 931-937 (2011).
    • (2011) Int. J. Cancer , vol.129 , pp. 931-937
    • Begg, C.B.1
  • 93
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumors: Impact on clinical outcome
    • Fridman, W. H., Pages, F., Fridman, C. S. & Galon, J. The immune contexture in human tumors: impact on clinical outcome. Nat. Rev. Cancer 12, 298-306 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Fridman, C.S.3    Galon, J.4
  • 94
    • 82555191051 scopus 로고    scopus 로고
    • Cancer Immunology-analysis of host and tumor factors for personalized medicine
    • Ogino, S., Galon, J., Fuchs, C. S. & Dranoff, G. Cancer Immunology-analysis of host and tumor factors for personalized medicine. Nat. Rev. Clin. Oncol. 8, 711-719 (2011).
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 711-719
    • Ogino, S.1    Galon, J.2    Fuchs, C.S.3    Dranoff, G.4
  • 95
    • 57749090255 scopus 로고    scopus 로고
    • Methylation of polycomb target genes in intestinal cancer is mediated by inflammation
    • Hahn, M. A. et al. Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Res. 68, 10280-10289 (2008).
    • (2008) Cancer Res , vol.68 , pp. 10280-10289
    • Hahn, M.A.1
  • 96
    • 69249142193 scopus 로고    scopus 로고
    • Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer
    • Edwards, R. A. et al. Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. Cancer Res. 69, 6423-6429 (2009).
    • (2009) Cancer Res , vol.69 , pp. 6423-6429
    • Edwards, R.A.1
  • 97
    • 77950346282 scopus 로고    scopus 로고
    • Immunity inflammation and cancer
    • Grivennikov, S. I., Greten, F. R. & Karin, M. Immunity, inflammation and cancer. Cell 140, 883-899 (2010).
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 98
    • 39449084394 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer
    • Tuynman, J. B. et al. Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer. Cancer Res. 68, 1213-1220 (2008).
    • (2008) Cancer Res , vol.68 , pp. 1213-1220
    • Tuynman, J.B.1
  • 99
    • 0036199569 scopus 로고    scopus 로고
    • Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells
    • Hawcroft, G. et al. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis 23, 107-114 (2002).
    • (2002) Carcinogenesis , vol.23 , pp. 107-114
    • Hawcroft, G.1
  • 100
    • 0842329914 scopus 로고    scopus 로고
    • Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines
    • Boon, E. M. et al. Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines. Br. J. Cancer 12, 224-229 (2004).
    • (2004) Br. J. Cancer , vol.12 , pp. 224-229
    • Boon, E.M.1
  • 101
    • 28544444039 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-b-catenin signaling axis
    • Castellone, M. D. et al. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-b-catenin signaling axis. Science 310, 1504-1510 (2005).
    • (2005) Science , vol.310 , pp. 1504-1510
    • Castellone, M.D.1
  • 102
    • 66549128430 scopus 로고    scopus 로고
    • Epithelial metaplasia: Adult stem cell reprogramming and (pre)neoplastic transformation mediated by inflammation?
    • Herfs, M., Hubert, P. & Delvenne, P. Epithelial metaplasia: adult stem cell reprogramming and (pre)neoplastic transformation mediated by inflammation? Trends Mol. Med. 15, 245-253 (2009).
    • (2009) Trends Mol. Med. , vol.15 , pp. 245-253
    • Herfs, M.1    Hubert, P.2    Delvenne, P.3
  • 103
    • 79953904617 scopus 로고    scopus 로고
    • Inflammatory mediators in breast cancer: Coordinate expression of TNFa & IL-1b with CCL2 and CCL5 and effects on epithelial-to-mesenchymal transition
    • Soria, G. et al. Inflammatory mediators in breast cancer: coordinate expression of TNFa & IL-1b with CCL2 and CCL5 and effects on epithelial-to-mesenchymal transition. BMC Cancer 11, 130 (2011).
    • (2011) BMC Cancer , vol.11 , pp. 130
    • Soria, G.1
  • 104
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: An alliance towards organ fibrosis and cancer progression
    • Lopez-Novoa, J. M. & Nieto, M. A. Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol. Med. 1, 202-314 (2009).
    • (2009) EMBO Mol. Med. , vol.1 , pp. 202-314
    • Lopez-Novoa, J.M.1    Nieto, M.A.2
  • 105
    • 74549155020 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers
    • Jang, T. J., Jeon, K, H. & Jung, K. H. Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers. Yonsei Med. J. 50, 818-824 (2009).
    • (2009) Yonsei Med. J. , vol.50 , pp. 818-824
    • Jang, T.J.1    Jeon, K.H.2    Jung, K.H.3
  • 106
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E2 induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
    • Dohadwala, M. et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E2 induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 66, 5338-5345 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 5338-5345
    • Dohadwala, M.1
  • 107
    • 44849100198 scopus 로고    scopus 로고
    • NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
    • Rius, J. et al. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 453, 807-811 (2008).
    • (2008) Nature , vol.453 , pp. 807-811
    • Rius, J.1
  • 108
    • 75149159101 scopus 로고    scopus 로고
    • Warburg effect revisited: An epigenetic link between glycolysis and gastric carcinogenesis
    • Liu, X. et al. Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis. Oncogene 29, 442-450 (2010).
    • (2010) Oncogene , vol.29 , pp. 442-450
    • Liu, X.1
  • 109
    • 79251478398 scopus 로고    scopus 로고
    • Contribution of platelets to tumour metastasis
    • Gay, L. J. & Felding-Habermann, B. Contribution of platelets to tumour metastasis. Nat. Rev. Cancer 11, 123-134 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 123-134
    • Gay, L.J.1    Felding-Habermann, B.2
  • 110
    • 84863011445 scopus 로고    scopus 로고
    • VEGF-D promotes tumor metastasis by regulating prostaglandin produced by the collecting lymphatic endothelium
    • Kamezis, T. et al. VEGF-D promotes tumor metastasis by regulating prostaglandin produced by the collecting lymphatic endothelium. Cancer Cell 21, 181-195 (2012).
    • (2012) Cancer Cell , vol.21 , pp. 181-195
    • Kamezis, T.1
  • 111
    • 33745962709 scopus 로고    scopus 로고
    • Fibrin and activated platelets cooperatively guide stem cells to a vascular injury and promote differentiation towards an endothelial cell phenotype
    • Boer, H. C. et al. Fibrin and activated platelets cooperatively guide stem cells to a vascular injury and promote differentiation towards an endothelial cell phenotype. Arterioscler. Thromb. Vasc. Biol. 26, 1653-1659 (2006).
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1653-1659
    • Boer, H.C.1
  • 112
    • 72249093615 scopus 로고    scopus 로고
    • Tumor self-seeding by circulating cancer cells
    • Kim, M. Y. et al. Tumor self-seeding by circulating cancer cells. Cell 139, 1315-1326 (2009).
    • (2009) Cell , vol.139 , pp. 1315-1326
    • Kim, M.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.