Astaxanthin treatment confers protection against oxidative stress in U937 cells stimulated with lipopolysaccharide reducing O2- production

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Franceschelli, Sara ^a   Pesce, Mirko ^a   Ferrone, Alessio ^a   De Lutiis, Maria Anna ^a   Patruno, Antonia ^a   Grilli, Alfredo ^a   Felaco, Mario ^a   Speranza, Lorenza ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ASTAXANTHIN; BACTERIUM LIPOPOLYSACCHARIDE; CATALASE; HEME OXYGENASE 1; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; IN VITRO STUDY; INFLAMMATION; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ANTIOXIDANTS; CATALASE; CELL SURVIVAL; HEME OXYGENASE-1; HUMANS; LIPOPOLYSACCHARIDES; NF-E2-RELATED FACTOR 2; NITROBLUE TETRAZOLIUM; OXIDATIVE STRESS; PROTECTIVE AGENTS; SUPEROXIDE DISMUTASE; SUPEROXIDES; U937 CELLS; XANTHOPHYLLS;

EID: 84895821685     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088359     Document Type: Article

References (32)

1. Paiva SA, Russell RM (1999) Beta-carotene and other carotenoids as antioxidants. J Am Coll Nutr 18(5): 426-33.
2. Riccioni G, Speranza L, Pesce M, Cusenza S, D'Orazio N, et al. (2012) Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. Nutrition 28(6): 605-10.
3. Riccioni G, D'Orazio N, Salvatore C, Franceschelli S, Pesce M, et al. (2012) Carotenoids and vitamins C and E in the prevention of cardiovascular disease. Int J Vitam Nutr Res 82(1): 15-26.
4. Riccioni G, D'Orazio N, Franceschelli S, Speranza L (2011) Marine carotenoids and cardiovascular risk markers. Mar Drugs 9(7): 1166-75.
5. Scapagnini G, Foresti R, Calabrese V, Giuffrida Stella AM, Green CJ, et al. (2002) Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers. Mol Pharmacol 61(3): 554-61. Erratum in: Mol Pharmacol 61(5): 1264. (Pubitemid 34171921)
6. Vomhof-Dekrey EE, Picklo Sr MJ (2012) The Nrf2-antioxidant response element pathway:a target for regulating energy metabolism. J Nutr Biochem 23(10): 1201-6.
7. Speranza L, Pesce M, Franceschelli S, Mastrangelo F, Patruno A, et al. (2012) The role of inducible nitric oxide synthase and haemoxygenase 1 in growth and development of dental tissue'. Cell Biochem Funct 30(3): 217-23.
8. Grilli A, De Lutiis MA, Patruno A, Speranza L, Gizzi F, et al. (2003) Inducible nitric oxide synthase and heme oxygenase-1 in rat heart: direct effect of chronic exposure to hypoxia. Ann Clin Lab Sci 33(2): 208-15. (Pubitemid 36705932)
9. Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, et al. (2004) Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. J Immunol 173(5): 3467-81. (Pubitemid 39142058)
10. Dröge W(2002) Free radicals in the physiological control of cell function. Physiol Rev 82(1): 47-95.
11. Patruno A, Franceschelli S, Pesce M, Maccallini C, Fantacuzzi M, et al. (2012) Novel aminobenzyl-acetamidine derivatives modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway. Biochim Biophys Acta 1820(12): 2095-104.
12. Speranza L, Pesce M, Franceschelli S, Bucciarelli T, Gallina S, et al. (2013) The biological evaluation of ADMA/SDMA and eNOS in patients with ACHF. Front Biosci (Elite Ed) 5: 551-7.
13. Franceschelli S, Pesce M, Vinciguerra I, Ferrone A, Riccioni G, et al. (2011) Licocalchone-C extracted from Glycyrrhizaglabra inhibits lipopolysaccharide-interferon-γ inflammation by improving antioxidantconditions and regulating inducible nitric oxide synthase expression. Molecules 16(7): 5720-34.
14. Speranza L, Franceschelli S, Pesce M, Reale M, Menghini L et al. (2010) Antiinflammatory effects in THP-1 cells treated with verbascoside. Phytother Res 24(9): 1398-404.
15. Patruno A, Amerio P, Pesce M, Vianale G, Di Luzio S, et al. (2010) Extremely low frequency electromagnetic fields modulate expression of inducible nitric oxide synthase, endothelial nitric oxide synthase and cyclooxygenase-2 in the human keratinocyte cell line HaCat: potential therapeutic effects in wound healing. Br J Dermatol 162(2): 258-66.
16. Speranza L, Pesce M, Patruno A, Franceschelli S, De Lutiis MA, et al. (2012) Astaxanthin treatment reduced oxidative induced pro-inflammatory cytokines secretion in U937: SHP-1 as a novel biological target. Mar Drugs 10(4): 890-9.
17. Babior BM (2000) Phagocytes and oxidative stress. Am J Med109(1): 33-44.
18. Elferink J (1984) Measurement of the metabolic burst in human neutrophils: a comparison between cytochrome c and NBT reduction. Res Commun Chem Pathol Pharmacol 43(2): 339-342.
19. Speranza L, Franceschelli S, Pesce M, Vinciguerra I, De Lutiis MA, et al. (2008) Phosphodiesterase type-5 inhibitor and oxidative stress. Int J Immunopathol Pharmacol 21(4): 879-89.
20. Speranza L, Franceschelli S, Riccioni G, Di Nicola M, Ruggeri B, et al. (2012) BNP and iNOS in decompensated chronic heart failure: a linear correlation. Front Biosci (Elite Ed) 4: 1255-62.
21. Miao L, St Clair DK (2009) Regulation of superoxide dismutase genes: implications in disease. Free Radic Biol Med47(4): 344-56.
22. Sun Y, Oberley LW (1996) Redox regulation of transcriptional activators Free Radic Biol Med 21: 335-348. (Pubitemid 26271723)
23. Ryter SW, Alam J, Choi AM (2006) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86(2): 583-650.
24. Kurata S, Matsumoto M, Tsuji Y, Nakajima H (1996) Lipopolysaccharide activates transcription of the hemeoxygenase gene in mouse M1 cells through oxidative activation of nuclear factor kappa B. Eur J Biochem 239: 566-571. (Pubitemid 26253072)
25. Cheng HW, Lee KC, Cheah KP, Chang ML, Lin CW, et al. (2013) Polygonumviviparum L. inhibits the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through haeme oxygenase-1 induction and activation of the Nrf2 pathway. J Sci Food Agric 93: 491-7.
26. Itoh K, Mochizuki M, Ishii Y, Ishii T, Shibata T, et al. (2004) Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). Mol Cell Biol24(1): 36-45. (Pubitemid 38010033)
27. He X, Ma Q (2009) NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation. Mol Pharmacol 76(6): 1265-78.
28. Ryter SW, Choi AM (2009) Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. Am J Respir Cell Mol Biol 41(3): 251-60.
29. Barbagallo I, Galvano F, Frigiola A, Cappello F, Riccioni G, et al. (2013) Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases. Antioxid Redox Signal 18(5): 507-21.
30. Iarlori C, Gambi D, Lugaresi A, Patruno A, Felaco M, et al. (2008) Reduction of free radicals in multiple sclerosis: effect of glatiramer acetate (Copaxone). Mult Scler 4(6): 739-48.
31. Stahl W, Sies H (2003) Antioxidant activity of carotenoids. Mol Aspects Med24(6): 345-51. (Pubitemid 37324647)
32. Miyashita K (2009) Function of marine carotenoids. Forum Nutr 61: 136-46.