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Volumn 19, Issue 9, 2011, Pages 781-796

PPARγ disease gene network and identification of therapeutic targets for prostate cancer

Author keywords

Direct repeat 2; Genome wide DR1 and DR2 PPAR genes; PPAR disease gene network; PPAR proteinprotein network; PPAR target genes in prostate cancer

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE KINASE 1; PROTEIN KINASE C ZETA; UNCLASSIFIED DRUG;

EID: 80054692069     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2011.568062     Document Type: Article
Times cited : (14)

References (83)
  • 1
    • 7944226627 scopus 로고    scopus 로고
    • Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
    • DOI 10.1016/j.ygeno.2004.08.010, PII S0888754304002277
    • Altenberg B, Greulich KO. (2004). Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics, 84, 1014-1020 (Pubitemid 39469126)
    • (2004) Genomics , vol.84 , Issue.6 , pp. 1014-1020
    • Altenberg, B.1    Greulich, K.O.2
  • 2
    • 33644960129 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorreduces damage produced by focal ischemia
    • Aronowski J. (2002). Peroxisome proliferator-activated receptorreduces damage produced by focal ischemia. Abstr-Soc Neurosci, Program No. 389.6
    • (2002) Abstr-Soc Neurosci, Program No 389.6
    • Aronowski, J.1
  • 4
    • 0030051176 scopus 로고    scopus 로고
    • An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction
    • DOI 10.1084/jem.183.1.277
    • Bernhagen J, Bacher M, Calandra T, Metz CN, Doty SB, Donnelly T, Bucala R. (1996). An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction. J Exp Med, 183, 277-282 (Pubitemid 26028767)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.1 , pp. 277-282
    • Bernhagen, J.1    Bacher, M.2    Calandra, T.3    Metz, C.N.4    Doty, S.B.5    Donnelly, T.6    Bucala, R.7
  • 6
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-γ agonist pioglitazone in a mouse model of Parkinson's disease
    • DOI 10.1046/j.1471-4159.2002.00990.x
    • Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC. (2002). Protective action of the peroxisome proliferatoractivated receptor-gamma agonist pioglitazone in a mouse model of Parkinsons disease. J Neurochem, 82, 615-624 (Pubitemid 34831499)
    • (2002) Journal of Neurochemistry , vol.82 , Issue.3 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3    Landreth, G.4    Launay, J.M.5    Hirsch, E.C.6
  • 7
    • 0033950982 scopus 로고    scopus 로고
    • 2
    • Butler R, Mitchell SH, Tindall DJ, Young CY. (2000). Nonapoptotic cell death associated with S-phase arrest of prostate cancer cells via the peroxisome proliferator-activated receptor gamma ligand, 15-deoxy-delta12,14-prostaglandin J2. Cell Growth Differ, 11, 49-61 (Pubitemid 30078666)
    • (2000) Cell Growth and Differentiation , vol.11 , Issue.1 , pp. 49-61
    • Butler, R.1    Mitchell, S.H.2    Tindall, D.J.3    Young, C.Y.F.4
  • 10
    • 0034652462 scopus 로고    scopus 로고
    • Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor γ in non-small cell lung cancer
    • Chang TH, Szabo E. (2000). Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer. Cancer Res, 60, 1129-1138 (Pubitemid 30129556)
    • (2000) Cancer Research , vol.60 , Issue.4 , pp. 1129-1138
    • Chang, T.-H.1    Szabo, E.2
  • 13
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation
    • Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. (2004). Protection by pioglitazone in the MPTP model of Parkinsons disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem, 88, 494-501 (Pubitemid 38084565)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.2 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 14
    • 0033839679 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor in prostatic adenocarcinoma: Correlation with tumor grading and combination endocrine treatment-related changes
    • del Vecchio MT, Tripodi SA, Arcuri F, Pergola L, Hako L, Vatti R, Cintorino M. (2000). Macrophage migration inhibitory factor in prostatic adenocarcinoma: correlation with tumor grading and combination endocrine treatment-related changes. Prostate, 45, 51-57
    • (2000) Prostate , vol.45 , pp. 51-57
    • Del Vecchio, M.T.1    Tripodi, S.A.2    Arcuri, F.3    Pergola, L.4    Hako, L.5    Vatti, R.6    Cintorino, M.7
  • 15
    • 77951249690 scopus 로고    scopus 로고
    • RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones
    • Della Peruta M, Giagulli C, Laudanna C, Scarpa A, Sorio C. (2010). RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones. Mol Cancer, 9, 61
    • (2010) Mol Cancer , vol.9 , pp. 61
    • Della Peruta, M.1    Giagulli, C.2    Laudanna, C.3    Scarpa, A.4    Sorio, C.5
  • 17
    • 66349132579 scopus 로고    scopus 로고
    • From disease ontology to disease-ontology lite: Statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations
    • Du P, Feng G, Flatow J, Song J, Holko M, Kibbe WA, Lin SM. (2009). From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations. Bioinformatics, 25, i63-i68
    • (2009) Bioinformatics , vol.25
    • Du, P.1    Feng, G.2    Flatow, J.3    Song, J.4    Holko, M.5    Kibbe, W.A.6    Lin, S.M.7
  • 18
    • 0031844535 scopus 로고    scopus 로고
    • The nuclear eicosanoid receptor, PPARγ, is aberrantly expressed in colonic cancers
    • DOI 10.1093/carcin/19.1.49
    • DuBois RN, Gupta R, Brockman J, Reddy BS, Krakow SL, Lazar MA. (1998). The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers. Carcinogenesis, 19, 49-53 (Pubitemid 28376825)
    • (1998) Carcinogenesis , vol.19 , Issue.1 , pp. 49-53
    • DuBois, R.N.1    Gupta, R.2    Brockman, J.3    Reddy, B.S.4    Krakow, S.L.5    Lazar, M.A.6
  • 19
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Müller C, Koshizuka K, Williamson EA, Park D, Asou H, Shintaku P, Said JW, Heber D, Koeffler HP. (1998). Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA, 95, 8806-8811
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8806-8811
    • Elstner, E.1    Müller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 20
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • DOI 10.1038/nm1025
    • Evans RM, Barish GD, Wang YX. (2004). PPARs and the complex journey to obesity. Nat Med, 10, 355-361. (Pubitemid 38508511)
    • (2004) Nature Medicine , vol.10 , Issue.4 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.-X.3
  • 21
    • 0345167182 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: Reduced expression of PPARgamma-coactivator 1 (PGC-1)
    • Feilchenfeldt J, Bründler MA, Soravia C, Tötsch M, Meier CA. (2004) Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1). Cancer Lett, 203, 25-33
    • (2004) Cancer Lett , vol.203 , pp. 25-33
    • Feilchenfeldt, J.B.1
  • 24
    • 0028717776 scopus 로고
    • Prostaglandin J2 and related compounds. Mode of action in G1 arrest and preclinical results
    • DOI 10.1111/j.1749-6632.1994.tb52733.x
    • Fukushima M, Sasaki H, Fukushima S. (1994). Prostaglandin J2 and related compounds. Mode of action in G1 arrest and preclinical results. Ann N Y Acad Sci, 744, 161-165 (Pubitemid 26005820)
    • (1994) Annals of the New York Academy of Sciences , vol.744 , pp. 161-165
    • Fukushima, M.1    Sasaki, H.2    Fukushima, S.3
  • 25
    • 78349249413 scopus 로고    scopus 로고
    • A topological description of hubs in amino acid interaction networks
    • (No other details in PubMed)
    • Gaci O. A topological description of hubs in amino acid interaction networks (2010). Adv Bioinform., 257512. (No other details in PubMed)
    • (2010) Adv Bioinform , pp. 257512
    • Gaci, O.1
  • 27
    • 0033206336 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death
    • Guan YF, Zhang YH, Breyer RM, Davis L, Breyer MD. (1999). Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death. Neoplasia, 1, 330-339
    • (1999) Neoplasia , vol.1 , pp. 330-339
    • Guan, Y.F.1    Zhang, Y.H.2    Breyer, R.M.3    Davis, L.4    Breyer, M.D.5
  • 28
    • 0035839608 scopus 로고    scopus 로고
    • Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells
    • Gupta RA, Brockman JA, Sarraf P, Willson TM, DuBois RN. (2001). Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. J Biol Chem, 276, 29681-29687
    • (2001) J Biol Chem , vol.276 , pp. 29681-29687
    • Gupta, R.A.1    Brockman, J.A.2    Sarraf, P.3    Willson, T.M.4    Dubois, R.N.5
  • 29
    • 0141960405 scopus 로고    scopus 로고
    • Control of COX-2 gene expression through peroxisome proliferator- activated receptor γ in human cervical cancer cells
    • Han S, Inoue H, Flowers LC, Sidell N. (2003). Control of COX-2 gene expression through peroxisome proliferator-activated receptor gamma in human cervical cancer cells. Clin Cancer Res, 9, 4627-4635 (Pubitemid 37248424)
    • (2003) Clinical Cancer Research , vol.9 , Issue.12 , pp. 4627-4635
    • Han, S.1    Inoue, H.2    Flowers, L.C.3    Sidell, N.4
  • 30
    • 0035132112 scopus 로고    scopus 로고
    • Novel expression and function of peroxisome proliferator-activated receptor gamma (PPARγ) in human neuroblastoma cells
    • Han SW, Greene ME, Pitts J, Wada RK, Sidell N. (2001). Novel expression and function of peroxisome proliferator-activated receptor gamma (PPARgamma) in human neuroblastoma cells. Clin Cancer Res, 7, 98-104 (Pubitemid 32110211)
    • (2001) Clinical Cancer Research , vol.7 , Issue.1 , pp. 98-104
    • Han, S.W.1    Greene, M.E.2    Pitts, J.3    Wada, R.K.4    Sidell, N.5
  • 32
    • 0035132169 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-γ in Alzheimer's disease [1]
    • Heneka MT, Landreth GE, Feinstein DL. (2001). Role for peroxisome proliferator-activated receptor-gamma in Alzheimers disease. Ann Neurol, 49, 276 (Pubitemid 32158009)
    • (2001) Annals of Neurology , vol.49 , Issue.2 , pp. 276
    • Heneka, M.T.1    Landreth, G.E.2    Feinstein, D.L.3
  • 33
    • 0036010783 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARγ) and its ligands: A review
    • DOI 10.1016/S0739-7240(01)00117-5, PII S0739724001001175
    • Houseknecht KL, Cole BM, Steele PJ. (2002). Peroxisome proliferatoractivated receptor gamma (PPARgamma) and its ligands: a review. Domest Anim Endocrinol, 22, 1-23 (Pubitemid 34438654)
    • (2002) Domestic Animal Endocrinology , vol.22 , Issue.1 , pp. 1-23
    • Houseknecht, K.L.1    Cole, B.M.2    Steele, P.J.3
  • 34
    • 0842311509 scopus 로고    scopus 로고
    • Peroxisome Proliferator-Activated Receptor γ: Implications for Cardiovascular Disease
    • DOI 10.1161/01.HYP.0000113626.76571.5b
    • Hsueh WA, Bruemmer D. (2004). Peroxisome proliferator-activated receptor gamma: implications for cardiovascular disease. Hypertension, 43, 297-305 (Pubitemid 38174129)
    • (2004) Hypertension , vol.43 , Issue.2 , pp. 297-305
    • Hsueh, W.A.1    Bruemmer, D.2
  • 36
    • 0034661871 scopus 로고    scopus 로고
    • Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients adenocarcinoma of the lung
    • DOI 10.1002/1097-0142(20000715)89:2<334::AID-CNCR18>3.0.CO;2-N
    • Kamimura A, Kamachi M, Nishihira J, Ogura S, Isobe H, Dosaka- Akita H, Ogata A, Shindoh M, Ohbuchi T, Kawakami Y. (2000). Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with adenocarcinoma of the lung. Cancer, 89, 334-341 (Pubitemid 30489881)
    • (2000) Cancer , vol.89 , Issue.2 , pp. 334-341
    • Kamimura, A.1    Kamachi, M.2    Nishihira, J.3    Ogura, S.4    Isobe, H.5    Dosaka-Akita, H.6    Ogata, A.7    Shindoh, M.8    Ohbuchi, T.9    Kawakami, Y.10
  • 37
    • 15744396059 scopus 로고    scopus 로고
    • PPAR-γ activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer
    • DOI 10.1593/neo.04601
    • Keshamouni VG, Arenberg DA, Reddy RC, Newstead MJ, Anthwal S, Standiford TJ. (2005). PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer. Neoplasia, 7, 294-301 (Pubitemid 40411641)
    • (2005) Neoplasia , vol.7 , Issue.3 , pp. 294-301
    • Keshamouni, V.G.1    Arenberg, D.A.2    Reddy, R.C.3    Newstead, M.J.4    Anthwal, S.5    Standiford, T.J.6
  • 39
    • 0027339849 scopus 로고
    • Prostaglandin A2 and delta 12-prostaglandin J2 induce apoptosis in L1210 cells
    • Kim IK, Lee JH, Sohn HW, Kim HS, Kim SH. (1993). Prostaglandin A2 and delta 12-prostaglandin J2 induce apoptosis in L1210 cells. FEBS Lett, 321, 209-214
    • (1993) FEBS Lett , vol.321 , pp. 209-214
    • Kim, I.K.1    Lee, J.H.2    Sohn, H.W.3    Kim, H.S.4    Kim, S.H.5
  • 41
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor γ (Troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
    • Kubota T, Koshizuka K, Williamson EA, Asou H, Said JW, Holden S, Miyoshi I, Koeffler HP. (1998). Ligand for peroxisome proliferatoractivated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res, 58, 3344-3352 (Pubitemid 28371075)
    • (1998) Cancer Research , vol.58 , Issue.15 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3    Asou, H.4    Said, J.W.5    Holden, S.6    Miyoshi, I.7    Koeffler, H.P.8
  • 42
    • 72249121406 scopus 로고    scopus 로고
    • Repression of the Na+/H+ exchanger 1 expression by PPARg activation is a potential new approach for specific inhibition of tumor cells growth in vitro and in vivo
    • Kumar AP, Quake AL, Chang MKX, Lim KSY, Eng CB, Singh R, Hewitt RE, Salto-Tellez M, Pervaiz S, Clement MV. (2009). Repression of the Na+/H+ exchanger 1 expression by PPARg activation is a potential new approach for specific inhibition of tumor cells growth in vitro and in vivo. Cancer Res., 69, 22, 8636-8644
    • (2009) Cancer Res , vol.69 , Issue.22 , pp. 8636-8644
    • Kumar, A.P.1    Quake, A.L.2    Mkx, C.3    Ksy, L.4    Eng, C.B.5    Singh, R.6    Hewitt, R.E.7    Salto-Tellez, M.8    Pervaiz, S.9    Clement, M.V.10
  • 43
    • 1542349774 scopus 로고    scopus 로고
    • Peroxisome Proliferator-activated Receptor γ Ligands Regulate Myeloperoxidase Expression in Macrophages by an Estrogen-dependent Mechanism Involving the -463GA Promoter Polymorphism
    • DOI 10.1074/jbc.M311625200
    • Kumar AP, Piedrafita FJ, Reynolds WF. (2004). Peroxisome proliferatoractivated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the ?463GA promoter polymorphism. J Biol Chem, 279, 8300-8315 (Pubitemid 38294722)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.9 , pp. 8300-8315
    • Kumar, A.P.1    Piedrafita, F.J.2    Reynolds, W.F.3
  • 44
    • 0033509041 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor in rheumatoid arthritis: Evidence of proinflammatory function and regulation by glucocorticoids
    • DOI 10.1002/1529-0131(199908)42:8<1601::AID-ANR6>3.0.CO;2-B
    • Leech M, Metz C, Hall P, Hutchinson P, Gianis K, Smith M, Weedon H, Holdsworth SR, Bucala R, Morand EF. (1999). Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids. Arthritis Rheum, 42, 1601-1608 (Pubitemid 30263626)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.8 , pp. 1601-1608
    • Leech, M.1    Metz, C.2    Hall, P.3    Hutchinson, P.4    Gianis, K.5    Smith, M.6    Weedon, H.7    Holdsworth, S.R.8    Bucala, R.9    Morand, E.F.10
  • 45
    • 0031969436 scopus 로고    scopus 로고
    • Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis
    • DOI 10.1002/1529-0131(199805)41:5<910::AID-ART19>3.0.CO;2-E
    • Leech M, Metz C, Santos L, Peng T, Holdsworth SR, Bucala R, Morand EF. (1998). Involvement of macrophage migration inhibitory factor in the evolution of rat adjuvant arthritis. Arthritis Rheum, 41, 910-917 (Pubitemid 28225792)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.5 , pp. 910-917
    • Leech, M.1    Metz, C.2    Santos, L.3    Peng, T.4    Holdsworth, S.R.5    Bucala, R.6    Morand, E.F.7
  • 46
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • Lehrke M, Lazar MA. (2005). The many faces of PPARgamma. Cell, 123, 993-999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Ma, L.2
  • 47
    • 0031989121 scopus 로고    scopus 로고
    • Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells
    • Lieberthal W, Menza SA, Levine JS. (1998). Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol, 274, F315-F327
    • (1998) Am J Physiol , vol.274
    • Lieberthal, W.1    Menza, S.A.2    Levine, J.S.3
  • 50
    • 1642494855 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose Increases the Efficacy of Adriamycin and Paclitaxel in Human Osteosarcoma and Non-Small Cell Lung Cancers in Vivo
    • DOI 10.1158/0008-5472.CAN-03-3294
    • Maschek G, Savaraj N, Priebe W, Braunschweiger P, Hamilton K, Tidmarsh GF, De Young LR, Lampidis TJ. (2004). 2-Deoxy-dglucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res, 64, 31-34 (Pubitemid 38114078)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 31-34
    • Maschek, G.1    Savaraj, N.2    Priebe, W.3    Braunschweiger, P.4    Hamilton, K.5    Tidmarsh, G.F.6    De Young, L.R.7    Lampidis, T.J.8
  • 51
    • 0031154718 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-lnduced arthritis in mice
    • Mikulowska A, Metz CN, Bucala R, Holmdahl R. (1997). Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-induced arthritis in mice. J Immunol, 158, 5514-5517 (Pubitemid 127681261)
    • (1997) Journal of Immunology , vol.158 , Issue.11 , pp. 5514-5517
    • Mikulowska, A.1    Metz, C.N.2    Bucala, R.3    Holmdahl, R.4
  • 53
    • 0034306992 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells
    • Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y. (2000). Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells. Cancer Res, 60, 5558-5564
    • (2000) Cancer Res , vol.60 , pp. 5558-5564
    • Motomura, W.1    Okumura, T.2    Takahashi, N.3    Obara, T.4    Kohgo, Y.5
  • 57
    • 1642293386 scopus 로고    scopus 로고
    • Thiazolidinediones inhibit cell growth of human oral squamous cell carcinoma in vitro independent of peroxisome proliferator-activated receptor γ
    • DOI 10.1016/S1368-8375(03)00108-8, PII S1368837503001088
    • Nakashiro K, Begum NM, Uchida D, Kawamata H, Shintani S, Sato M, Hamakawa H. (2003). Thiazolidinediones inhibit cell growth of human oral squamous cell carcinoma in vitro independent of peroxisome proliferator-activated receptor gamma. Oral Oncol, 39, 855-861 (Pubitemid 38373469)
    • (2003) Oral Oncology , vol.39 , Issue.8 , pp. 855-861
    • Nakashiro, K.-I.1    Begum, N.-M.2    Uchida, D.3    Kawamata, H.4    Shintani, S.5    Sato, M.6    Hamakawa, H.7
  • 58
    • 55749101777 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, Megens E, Denissov S, Brgesen M, Francoijs KJ, Mandrup S, Stunnenberg HG. (2008). Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev, 22, 2953-2967
    • (2008) Genes Dev , vol.22 , pp. 2953-2967
    • Nielsen, R.1    Pedersen, T.A.2    Hagenbeek, D.3    Moulos, P.4    Siersbaek, R.5    Megens, E.6    Denissov, S.7    Brgesen, M.8    Francoijs, K.J.9    Mandrup, S.10    Stunnenberg, H.G.11
  • 59
    • 0035341427 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-γ
    • DOI 10.1016/S0165-5728(01)00285-5, PII S0165572801002855
    • Niino M, Iwabuchi K, Kikuchi S, Ato M, Morohashi T, Ogata A, Tashiro K, Onoé K. (2001). Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma. J Neuroimmunol, 116, 40-48 (Pubitemid 32322638)
    • (2001) Journal of Neuroimmunology , vol.116 , Issue.1 , pp. 40-48
    • Niino, M.1    Iwabuchi, K.2    Kikuchi, S.3    Ato, M.4    Morohashi, T.5    Ogata, A.6    Tashiro, K.7    Onoe, K.8
  • 60
    • 17444371632 scopus 로고    scopus 로고
    • Peroxisome proliterator-activated receptors in squamous cell carcinoma and its precursors
    • DOI 10.1111/j.0303-6987.2005.00345.x
    • Nijsten T, Geluyckens E, Colpaert C, Lambert J. (2005). Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors. J Cutan Pathol, 32, 340-347 (Pubitemid 40547792)
    • (2005) Journal of Cutaneous Pathology , vol.32 , Issue.5 , pp. 340-347
    • Nijsten, T.1    Geluyckens, E.2    Colpaert, C.3    Lambert, J.4
  • 61
    • 58849143927 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: Implications for chemoprevention
    • Ondrey F. (2009). Peroxisome proliferator-activated receptor gamma pathway targeting in carcinogenesis: implications for chemoprevention. Clin Cancer Res, 15, 2-8
    • (2009) Clin Cancer Res , vol.15 , pp. 2-8
    • Ondrey, F.1
  • 63
    • 25144475465 scopus 로고    scopus 로고
    • PPARγ as a therapeutic target for tumor angiogenesis and metastasis
    • Panigrahy D, Huang S, Kieran MW, Kaipainen A. (2005). PPARgamma as a therapeutic target for tumor angiogenesis and metastasis. Cancer Biol Ther, 4, 687-693 (Pubitemid 41351164)
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.7 , pp. 687-693
    • Panigrahy, D.1    Huang, S.2    Kieran, M.W.3    Kaipainen, A.4
  • 64
    • 0035873953 scopus 로고    scopus 로고
    • Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
    • DOI 10.1016/S0960-9822(01)00225-1
    • Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH. (2001). Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. Curr Biol, 11, 764-768 (Pubitemid 32442793)
    • (2001) Current Biology , vol.11 , Issue.10 , pp. 764-768
    • Patel, L.1    Pass, I.2    Coxon, P.3    Downes, C.P.4    Smith, S.A.5    Macphee, C.H.6
  • 67
    • 67649641618 scopus 로고    scopus 로고
    • Genetic and pharmacological interaction network of targets and drugs
    • Sakharkar MK, Sakharkar KR. (2008). Genetic and pharmacological interaction network of targets and drugs. Int J Integ Biol, 4, 1-8
    • (2008) Int J Integ Biol , vol.4 , pp. 1-8
    • Sakharkar, M.K.1    Sakharkar, K.R.2
  • 70
    • 70350664654 scopus 로고    scopus 로고
    • Analyzing biological network parameters with CentiScaPe
    • Scardoni G, Petterlini M, Laudanna C. (2009). Analyzing biological network parameters with CentiScaPe. Bioinformatics, 25, 2857-2859.
    • (2009) Bioinformatics , vol.25 , pp. 2857-2859
    • Scardoni, G.1    Petterlini, M.2    Laudanna, C.3
  • 72
    • 12844281747 scopus 로고    scopus 로고
    • A peroxisome proliferator-activated receptor-γ agonist reduces infarct size in transient but not in permanent ischemia
    • DOI 10.1161/01.STR.0000152271.21943.a2
    • Shimazu T, Inoue I, Araki N, Asano Y, Sawada M, Furuya D, Nagoya H, Greenberg JH. (2005). A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia. Stroke, 36, 353-359 (Pubitemid 40170822)
    • (2005) Stroke , vol.36 , Issue.2 , pp. 353-359
    • Shimazu, T.1    Inoue, I.2    Araki, N.3    Asano, Y.4    Sawada, M.5    Furuya, D.6    Nagoya, H.7    Greenberg, J.H.8
  • 73
    • 33751081567 scopus 로고    scopus 로고
    • Mechanisms of action of novel agents for prostate cancer chemoprevention
    • DOI 10.1677/erc.1.01126
    • Singh RP, Agarwal R. (2006). Mechanisms of action of novel agents for prostate cancer chemoprevention. Endocr Relat Cancer, 13, 751-778 (Pubitemid 44763256)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.3 , pp. 751-778
    • Singh, R.P.1    Agarwal, R.2
  • 75
    • 10044289268 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ ligands reduce inflammation and infarction size in transient focal ischemia
    • DOI 10.1016/j.neuroscience.2004.10.021, PII S0306452204009571
    • Sundararajan S, Gamboa JL, Victor NA, Wanderi EW, Lust WD, Landreth GE. (2005). Peroxisome proliferator-activated receptorgamma ligands reduce inflammation and infarction size in transient focal ischemia. Neuroscience, 130, 685-696 (Pubitemid 39601441)
    • (2005) Neuroscience , vol.130 , Issue.3 , pp. 685-696
    • Sundararajan, S.1    Gamboa, J.L.2    Victor, N.A.3    Wanderi, E.W.4    Lust, W.D.5    Landreth, G.E.6
  • 76
    • 0036247888 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator activated receptor-gamma in non-small cell lung carcinoma: Correlation with histological type and grade
    • DOI 10.1016/S0169-5002(02)00013-2, PII S0169500202000132
    • Theocharis S, Kanelli H, Politi E, Margeli A, Karkandaris C, Philippides T, Koutselinis A. (2002). Expression of peroxisome proliferator activated receptor-gamma in non-small cell lung carcinoma: correlation with histological type and grade. Lung Cancer,36,3, 249-255 (Pubitemid 34497122)
    • (2002) Lung Cancer , vol.36 , Issue.3 , pp. 249-255
    • Theocharis, S.1    Kanelli, H.2    Politi, E.3    Margeli, A.4    Karkandaris, C.5    Philippides, T.6    Koutselinis, A.7
  • 79
    • 71549131007 scopus 로고    scopus 로고
    • Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human
    • Venkatachalam G, Kumar AP, Yue LS, Pervaiz S, Clement MV, Sakharkar MK. (2009). Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human. BMC Genomics, 10 (Suppl 3), S5
    • (2009) BMC Genomics , vol.10 , Issue.SUPPL. 3
    • Venkatachalam, G.1    Kumar, A.P.2    Yue, L.S.3    Pervaiz, S.4    Clement, M.V.5    Sakharkar, M.K.6
  • 83
    • 0037221379 scopus 로고    scopus 로고
    • The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
    • DOI 10.2165/00023210-200317010-00003
    • Watson GS, Craft S. (2003). The role of insulin resistance in the pathogenesis of Alzheimers disease: implications for treatment. CNS Drugs, 17, 27-45 (Pubitemid 36044347)
    • (2003) CNS Drugs , vol.17 , Issue.1 , pp. 27-45
    • Watson, G.S.1    Craft, S.2


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