Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: Ameliorating effects of (-)-epigallocatechin-3-gallate

Journal of Nutritional Biochemistry

Volumn 23, Issue 7, 2012, Pages 716-724

  Yan, Jiong ^a   Feng, Zhihui ^a,b   Liu, Jia ^a   Shen, Weili ^c   Wang, Ying ^d   Wertz, Karin ^d   Weber, Peter ^d   Long, Jiangang ^a   Liu, Jiankang ^a,e  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d DSM NUTRITIONAL PRODUCTS LTD   (Switzerland)

^e UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Autophagy; Fission; Hyperglycemia; Insulin resistance; Mitochondrial dysfunction; Oxidative stress; Type 2 diabetes mellitus

Indexed keywords

BECLIN 1; CELL PROTEIN; DYNAMIN RELATED PROTEIN 1; EPIGALLOCATECHIN GALLATE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; AUTOPHAGY; BIOGENESIS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; IMPAIRED GLUCOSE TOLERANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; RAT; SKELETAL MUSCLE;

ANIMALS; AUTOPHAGY; BLOOD GLUCOSE; CATECHIN; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; FASTING; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MALE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SKELETAL; OXIDATIVE STRESS; RATS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

ANIMALIA; RATTUS;

EID: 84862309959     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.03.014     Document Type: Article

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