-
1
-
-
31044433663
-
Macrophages: obligate partners for tumor cell migration, invasion, and metastasis
-
Condeelis J and Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell. 2006; 124:263-266.
-
(2006)
Cell.
, vol.124
, pp. 263-266
-
-
Condeelis, J.1
Pollard, J.W.2
-
2
-
-
63149160727
-
Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB
-
Hagemann T, Biswas SK, Lawrence T, Sica A and Lewis CE. Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. Blood. 2009; 113:3139-3146.
-
(2009)
Blood.
, vol.113
, pp. 3139-3146
-
-
Hagemann, T.1
Biswas, S.K.2
Lawrence, T.3
Sica, A.4
Lewis, C.E.5
-
3
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004; 4:71-78.
-
(2004)
Nat Rev Cancer.
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
4
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A and Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest. 2012; 122:787-795.
-
(2012)
J Clin Invest.
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
6
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, De Nardo D, Gohel TD, Emde M, Schmidleithner L, Ganesan H, Nino-Castro A, Mallmann MR, Labzin L, Theis H, Kraut M, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity. 2014; 40:274-288.
-
(2014)
Immunity.
, vol.40
, pp. 274-288
-
-
Xue, J.1
Schmidt, S.V.2
Sander, J.3
Draffehn, A.4
Krebs, W.5
Quester, I.6
De Nardo, D.7
Gohel, T.D.8
Emde, M.9
Schmidleithner, L.10
Ganesan, H.11
Nino-Castro, A.12
Mallmann, M.R.13
Labzin, L.14
Theis, H.15
Kraut, M.16
-
7
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ and Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010; 141:39-51.
-
(2010)
Cell.
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
8
-
-
84885951882
-
Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse
-
Reinartz S, Schumann T, Finkernagel F, Wortmann A, Jansen JM, Meissner W, Krause M, Schworer AM, Wagner U, Muller-Brusselbach S and Muller R. Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse. Int J Cancer. 2014; 134:32-42.
-
(2014)
Int J Cancer.
, vol.134
, pp. 32-42
-
-
Reinartz, S.1
Schumann, T.2
Finkernagel, F.3
Wortmann, A.4
Jansen, J.M.5
Meissner, W.6
Krause, M.7
Schworer, A.M.8
Wagner, U.9
Muller-Brusselbach, S.10
Muller, R.11
-
9
-
-
27944505915
-
PPARs in diseases: control mechanisms of inflammation
-
Kostadinova R, Wahli W and Michalik L. PPARs in diseases: control mechanisms of inflammation. Curr Med Chem. 2005; 12:2995-3009.
-
(2005)
Curr Med Chem.
, vol.12
, pp. 2995-3009
-
-
Kostadinova, R.1
Wahli, W.2
Michalik, L.3
-
10
-
-
84863104065
-
PPARs at the crossroads of lipid signaling and inflammation
-
Wahli W and Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol Metab. 2012; 23:351-363.
-
(2012)
Trends Endocrinol Metab.
, vol.23
, pp. 351-363
-
-
Wahli, W.1
Michalik, L.2
-
11
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
-
Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD and Gonzalez FJ. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol. 2000; 20:5119-5128.
-
(2000)
Mol Cell Biol.
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.2
Li, W.3
Ward, J.M.4
Gavrilova, O.5
Everett, C.6
Reitman, M.L.7
Hudson, L.D.8
Gonzalez, F.J.9
-
12
-
-
64049095625
-
Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing
-
Chong HC, Tan MJ, Philippe V, Tan SH, Tan CK, Ku CW, Goh YY, Wahli W, Michalik L and Tan NS. Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing. J Cell Biol. 2009; 184:817-831.
-
(2009)
J Cell Biol.
, vol.184
, pp. 817-831
-
-
Chong, H.C.1
Tan, M.J.2
Philippe, V.3
Tan, S.H.4
Tan, C.K.5
Ku, C.W.6
Goh, Y.Y.7
Wahli, W.8
Michalik, L.9
Tan, N.S.10
-
13
-
-
44349112305
-
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
-
Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B and Lee CH. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab. 2008; 7:485-495.
-
(2008)
Cell Metab.
, vol.7
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
Lee, C.H.7
-
14
-
-
44349161098
-
Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW and Chawla A. Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab. 2008; 7:496-507.
-
(2008)
Cell Metab.
, vol.7
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
15
-
-
84857641358
-
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
-
Peters JM, Shah YM and Gonzalez FJ. The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer. 2012; 12:181-195.
-
(2012)
Nat Rev Cancer.
, vol.12
, pp. 181-195
-
-
Peters, J.M.1
Shah, Y.M.2
Gonzalez, F.J.3
-
16
-
-
0033105510
-
Molecular recognition of fatty acids by peroxisome proliferatoractivated receptors
-
Xu HE, Lambert MH, Montana VG, Parks DJ, Blanchard SG, Brown PJ, Sternbach DD, Lehmann JM, Wisely GB, Willson TM, Kliewer SA and Milburn MV. Molecular recognition of fatty acids by peroxisome proliferatoractivated receptors. Mol Cell. 1999; 3:397-403.
-
(1999)
Mol Cell.
, vol.3
, pp. 397-403
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
Parks, D.J.4
Blanchard, S.G.5
Brown, P.J.6
Sternbach, D.D.7
Lehmann, J.M.8
Wisely, G.B.9
Willson, T.M.10
Kliewer, S.A.11
Milburn, M.V.12
-
17
-
-
0033564698
-
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta
-
Lim H, Gupta RA, Ma WG, Paria BC, Moller DE, Morrow JD, DuBois RN, Trzaskos JM and Dey SK. Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev. 1999; 13:1561-1574.
-
(1999)
Genes Dev.
, vol.13
, pp. 1561-1574
-
-
Lim, H.1
Gupta, R.A.2
Ma, W.G.3
Paria, B.C.4
Moller, D.E.5
Morrow, J.D.6
DuBois, R.N.7
Trzaskos, J.M.8
Dey, S.K.9
-
18
-
-
74549222441
-
15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor β/δ agonist
-
Naruhn S, Meissner W, Adhikary T, Kaddatz K, Klein T, Watzer B, Müller-Brüsselbach S and Müller R. 15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor β/δ agonist. Mol Pharmacol. 2010; 77:171-184.
-
(2010)
Mol Pharmacol.
, vol.77
, pp. 171-184
-
-
Naruhn, S.1
Meissner, W.2
Adhikary, T.3
Kaddatz, K.4
Klein, T.5
Watzer, B.6
Müller-Brüsselbach, S.7
Müller, R.8
-
19
-
-
79251633165
-
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta)
-
Adhikary T, Kaddatz K, Finkernagel F, Schönbauer A, Meissner W, Scharfe M, Jarek M, Blöcker H, Müller-Brüsselbach S and Müller R. Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). PLoS One. 2011; 6:e16344.
-
(2011)
PLoS One
, vol.6
, pp. e16344
-
-
Adhikary, T.1
Kaddatz, K.2
Finkernagel, F.3
Schönbauer, A.4
Meissner, W.5
Scharfe, M.6
Jarek, M.7
Blöcker, H.8
Müller-Brüsselbach, S.9
Müller, R.10
-
20
-
-
80054786234
-
High-affinity peroxisome proliferator-activated receptor beta/delta-specific ligands with pure antagonistic or inverse agonistic properties
-
Naruhn S, Toth PM, Adhikary T, Kaddatz K, Pape V, Dörr S, Klebe G, Müller-Brüsselbach S, Diederich WE and Müller R. High-affinity peroxisome proliferator-activated receptor beta/delta-specific ligands with pure antagonistic or inverse agonistic properties. Mol Pharmacol. 2011; 80:828-838.
-
(2011)
Mol Pharmacol.
, vol.80
, pp. 828-838
-
-
Naruhn, S.1
Toth, P.M.2
Adhikary, T.3
Kaddatz, K.4
Pape, V.5
Dörr, S.6
Klebe, G.7
Müller-Brüsselbach, S.8
Diederich, W.E.9
Müller, R.10
-
21
-
-
84887074461
-
Inverse PPARbeta/delta agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion
-
Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, et al. Inverse PPARbeta/delta agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion. Oncogene. 2013; 32:5241-5252.
-
(2013)
Oncogene.
, vol.32
, pp. 5241-5252
-
-
Adhikary, T.1
Brandt, D.T.2
Kaddatz, K.3
Stockert, J.4
Naruhn, S.5
Meissner, W.6
Finkernagel, F.7
Obert, J.8
Lieber, S.9
Scharfe, M.10
Jarek, M.11
Toth, P.M.12
Scheer, F.13
Diederich, W.E.14
Reinartz, S.15
Grosse, R.16
-
22
-
-
44949181877
-
SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta
-
Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T and Nagai R. SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta. Nat Med. 2008; 14:656-666.
-
(2008)
Nat Med.
, vol.14
, pp. 656-666
-
-
Oishi, Y.1
Manabe, I.2
Tobe, K.3
Ohsugi, M.4
Kubota, T.5
Fujiu, K.6
Maemura, K.7
Kubota, N.8
Kadowaki, T.9
Nagai, R.10
-
23
-
-
0142116239
-
Transcriptional repression of atherogenic inflammation: modulation by PPARdelta
-
Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM and Curtiss LK. Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science. 2003; 302:453-457.
-
(2003)
Science.
, vol.302
, pp. 453-457
-
-
Lee, C.H.1
Chawla, A.2
Urbiztondo, N.3
Liao, D.4
Boisvert, W.A.5
Evans, R.M.6
Curtiss, L.K.7
-
24
-
-
13844256366
-
Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes
-
Planavila A, Rodriguez-Calvo R, Jove M, Michalik L, Wahli W, Laguna JC and Vazquez-Carrera M. Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes. Cardiovasc Res. 2005; 65:832-841.
-
(2005)
Cardiovasc Res.
, vol.65
, pp. 832-841
-
-
Planavila, A.1
Rodriguez-Calvo, R.2
Jove, M.3
Michalik, L.4
Wahli, W.5
Laguna, J.C.6
Vazquez-Carrera, M.7
-
25
-
-
10744228768
-
Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin
-
Westergaard M, Henningsen J, Johansen C, Rasmussen S, Svendsen ML, Jensen UB, Schroder HD, Staels B, Iversen L, Bolund L, Kragballe K and Kristiansen K. Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin. J Invest Dermatol. 2003; 121:1104-1117.
-
(2003)
J Invest Dermatol.
, vol.121
, pp. 1104-1117
-
-
Westergaard, M.1
Henningsen, J.2
Johansen, C.3
Rasmussen, S.4
Svendsen, M.L.5
Jensen, U.B.6
Schroder, H.D.7
Staels, B.8
Iversen, L.9
Bolund, L.10
Kragballe, K.11
Kristiansen, K.12
-
26
-
-
33744519163
-
PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes
-
Ding G, Cheng L, Qin Q, Frontin S and Yang Q. PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes. J Mol Cell Cardiol. 2006; 40:821-828.
-
(2006)
J Mol Cell Cardiol.
, vol.40
, pp. 821-828
-
-
Ding, G.1
Cheng, L.2
Qin, Q.3
Frontin, S.4
Yang, Q.5
-
27
-
-
84876964236
-
Regulation of TAK1/TAB1-Mediated IL-1beta Signaling by Cytoplasmic PPARbeta/delta
-
Stockert J, Wolf A, Kaddatz K, Schnitzer E, Finkernagel F, Meissner W, Müller-Brüsselbach S, Kracht M and Müller R. Regulation of TAK1/TAB1-Mediated IL-1beta Signaling by Cytoplasmic PPARbeta/delta. PLoS One. 2013; 8:e63011.
-
(2013)
PLoS One
, vol.8
, pp. e63011
-
-
Stockert, J.1
Wolf, A.2
Kaddatz, K.3
Schnitzer, E.4
Finkernagel, F.5
Meissner, W.6
Müller-Brüsselbach, S.7
Kracht, M.8
Müller, R.9
-
28
-
-
84931052960
-
The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state
-
in press
-
Adhikary T, Wortmann A, Schumann T, Finkernagel F, Lieber S, Roth K, Toth PM, Diederich WE, Nist A, Stiewe T, Kleinesudeik L, Reinartz S, Müller-Brüsselbach S and Müller R. The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state. Nucl Acids Res. 2015:in press.
-
(2015)
Nucl Acids Res.
-
-
Adhikary, T.1
Wortmann, A.2
Schumann, T.3
Finkernagel, F.4
Lieber, S.5
Roth, K.6
Toth, P.M.7
Diederich, W.E.8
Nist, A.9
Stiewe, T.10
Kleinesudeik, L.11
Reinartz, S.12
Müller-Brüsselbach, S.13
Müller, R.14
-
29
-
-
0028116948
-
Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors
-
Yamashiro S, Takeya M, Nishi T, Kuratsu J, Yoshimura T, Ushio Y and Takahashi K. Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors. Am J Pathol. 1994; 145:856-867.
-
(1994)
Am J Pathol.
, vol.145
, pp. 856-867
-
-
Yamashiro, S.1
Takeya, M.2
Nishi, T.3
Kuratsu, J.4
Yoshimura, T.5
Ushio, Y.6
Takahashi, K.7
-
30
-
-
0037613824
-
Tumor-associated fibroblasts recruit blood monocytes into tumor tissue
-
Silzle T, Kreutz M, Dobler MA, Brockhoff G, Knuechel R and Kunz-Schughart LA. Tumor-associated fibroblasts recruit blood monocytes into tumor tissue. Eur J Immunol. 2003; 33:1311-1320.
-
(2003)
Eur J Immunol.
, vol.33
, pp. 1311-1320
-
-
Silzle, T.1
Kreutz, M.2
Dobler, M.A.3
Brockhoff, G.4
Knuechel, R.5
Kunz-Schughart, L.A.6
-
31
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
Murdoch C, Giannoudis A and Lewis CE. Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood. 2004; 104:2224-2234.
-
(2004)
Blood.
, vol.104
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
32
-
-
84891138385
-
Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research
-
Ahmed N and Stenvers KL. Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research. Front Oncol. 2013; 3:256.
-
(2013)
Front Oncol
, vol.3
, pp. 256
-
-
Ahmed, N.1
Stenvers, K.L.2
-
33
-
-
34547956322
-
Three Members of the Human Pyruvate Dehydrogenase Kinase Gene Family Are Direct Targets of the Peroxisome Proliferator-activated Receptor β/δ
-
Degenhardt T, Saramaki A, Malinen M, Rieck M, Vaisanen S, Huotari A, Herzig KH, Müller R and Carlberg C. Three Members of the Human Pyruvate Dehydrogenase Kinase Gene Family Are Direct Targets of the Peroxisome Proliferator-activated Receptor β/δ. J Mol Biol. 2007.
-
(2007)
J Mol Biol.
-
-
Degenhardt, T.1
Saramaki, A.2
Malinen, M.3
Rieck, M.4
Vaisanen, S.5
Huotari, A.6
Herzig, K.H.7
Müller, R.8
Carlberg, C.9
-
34
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Network TCGAR. Integrated genomic analyses of ovarian carcinoma. Nature. 2011; 474:609-615.
-
(2011)
Nature.
, vol.474
, pp. 609-615
-
-
-
35
-
-
41149157649
-
TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4
-
Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR and Massague J. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell. 2008; 133:66-77.
-
(2008)
Cell.
, vol.133
, pp. 66-77
-
-
Padua, D.1
Zhang, X.H.2
Wang, Q.3
Nadal, C.4
Gerald, W.L.5
Gomis, R.R.6
Massague, J.7
-
36
-
-
0034700110
-
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
-
Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK and DuBois RN. Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc Natl Acad Sci U S A. 2000; 97:13275-13280.
-
(2000)
Proc Natl Acad Sci U S A.
, vol.97
, pp. 13275-13280
-
-
Gupta, R.A.1
Tan, J.2
Krause, W.F.3
Geraci, M.W.4
Willson, T.M.5
Dey, S.K.6
DuBois, R.N.7
-
37
-
-
0035941270
-
The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages
-
Vosper H, Patel L, Graham TL, Khoudoli GA, Hill A, Macphee CH, Pinto I, Smith SA, Suckling KE, Wolf CR and Palmer CN. The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages. J Biol Chem. 2001; 276:44258-44265.
-
(2001)
J Biol Chem.
, vol.276
, pp. 44258-44265
-
-
Vosper, H.1
Patel, L.2
Graham, T.L.3
Khoudoli, G.A.4
Hill, A.5
Macphee, C.H.6
Pinto, I.7
Smith, S.A.8
Suckling, K.E.9
Wolf, C.R.10
Palmer, C.N.11
-
38
-
-
0022553161
-
Isolation and characterization of a cellular protein-lipid complex from ascites fluid caused by various neoplasms
-
Caselmann WH and Jungst D. Isolation and characterization of a cellular protein-lipid complex from ascites fluid caused by various neoplasms. Cancer Res. 1986; 46:1547-1552.
-
(1986)
Cancer Res.
, vol.46
, pp. 1547-1552
-
-
Caselmann, W.H.1
Jungst, D.2
-
39
-
-
0031023905
-
Subcutaneous, omentum and tumor fatty acid composition, and serum insulin status in patients with benign or cancerous ovarian or endometrial tumors. Do tumors preferentially utilize polyunsaturated fatty acids?
-
Yam D, Ben-Hur H, Dgani R, Fink A, Shani A and Berry EM. Subcutaneous, omentum and tumor fatty acid composition, and serum insulin status in patients with benign or cancerous ovarian or endometrial tumors. Do tumors preferentially utilize polyunsaturated fatty acids? Cancer Lett. 1997; 111:179-185.
-
(1997)
Cancer Lett.
, vol.111
, pp. 179-185
-
-
Yam, D.1
Ben-Hur, H.2
Dgani, R.3
Fink, A.4
Shani, A.5
Berry, E.M.6
-
40
-
-
0031007392
-
Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
-
Gansler TS, Hardman W, 3rd, Hunt DA, Schaffel S and Hennigar RA. Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum Pathol. 1997; 28:686-692.
-
(1997)
Hum Pathol.
, vol.28
, pp. 686-692
-
-
Gansler, T.S.1
Hardman 3rd, W.2
Hunt, D.A.3
Schaffel, S.4
Hennigar, R.A.5
-
41
-
-
78149423097
-
Association of lipid metabolism with ovarian cancer
-
Tania M, Khan MA and Song Y. Association of lipid metabolism with ovarian cancer. Curr Oncol. 2010; 17:6-11.
-
(2010)
Curr Oncol.
, vol.17
, pp. 6-11
-
-
Tania, M.1
Khan, M.A.2
Song, Y.3
-
42
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K and Lengyel E. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med. 2011; 17:1498-1503.
-
(2011)
Nat Med.
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
Kenny, H.A.2
Penicka, C.V.3
Ladanyi, A.4
Buell-Gutbrod, R.5
Zillhardt, M.R.6
Romero, I.L.7
Carey, M.S.8
Mills, G.B.9
Hotamisligil, G.S.10
Yamada, S.D.11
Peter, M.E.12
Gwin, K.13
Lengyel, E.14
-
43
-
-
0032702547
-
Changes in plasma free fatty acid concentrations in rheumatoid arthritis patients during fasting and their effects upon T-lymphocyte proliferation
-
Fraser DA, Thoen J, Rustan AC, Forre O and Kjeldsen-Kragh J. Changes in plasma free fatty acid concentrations in rheumatoid arthritis patients during fasting and their effects upon T-lymphocyte proliferation. Rheumatology (Oxford). 1999; 38:948-952.
-
(1999)
Rheumatology (Oxford).
, vol.38
, pp. 948-952
-
-
Fraser, D.A.1
Thoen, J.2
Rustan, A.C.3
Forre, O.4
Kjeldsen-Kragh, J.5
-
44
-
-
32644454369
-
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity
-
Mandard S, Zandbergen F, van Straten E, Wahli W, Kuipers F, Muller M and Kersten S. The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity. J Biol Chem. 2006; 281:934-944.
-
(2006)
J Biol Chem.
, vol.281
, pp. 934-944
-
-
Mandard, S.1
Zandbergen, F.2
van Straten, E.3
Wahli, W.4
Kuipers, F.5
Muller, M.6
Kersten, S.7
-
45
-
-
77956547390
-
Transcriptional profiling identifies functional interactions of TGFβ and PPARβ/δ signaling: synergistic induction of ANGPTL4 transcription
-
Kaddatz K, Adhikary T, Finkernagel F, Meissner W, Müller-Brüsselbach S and Müller R. Transcriptional profiling identifies functional interactions of TGFβ and PPARβ/δ signaling: synergistic induction of ANGPTL4 transcription. J Biol Chem. 2010; 285:29469-29479.
-
(2010)
J Biol Chem.
, vol.285
, pp. 29469-29479
-
-
Kaddatz, K.1
Adhikary, T.2
Finkernagel, F.3
Meissner, W.4
Müller-Brüsselbach, S.5
Müller, R.6
-
46
-
-
84859450817
-
Angiopoietin-like 4: a decade of research
-
Zhu P, Goh YY, Chin HF, Kersten S and Tan NS. Angiopoietin-like 4: a decade of research. Biosci Rep. 2012; 32:211-219.
-
(2012)
Biosci Rep.
, vol.32
, pp. 211-219
-
-
Zhu, P.1
Goh, Y.Y.2
Chin, H.F.3
Kersten, S.4
Tan, N.S.5
-
47
-
-
65449159747
-
A compact VEGF signature associated with distant metastases and poor outcomes
-
Hu Z, Fan C, Livasy C, He X, Oh DS, Ewend MG, Carey LA, Subramanian S, West R, Ikpatt F, Olopade OI, van de Rijn M and Perou CM. A compact VEGF signature associated with distant metastases and poor outcomes. BMC Med. 2009; 7:9.
-
(2009)
BMC Med
, vol.7
, pp. 9
-
-
Hu, Z.1
Fan, C.2
Livasy, C.3
He, X.4
Oh, D.S.5
Ewend, M.G.6
Carey, L.A.7
Subramanian, S.8
West, R.9
Ikpatt, F.10
Olopade, O.I.11
van de Rijn, M.12
Perou, C.M.13
-
48
-
-
79952498225
-
Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O(2)(-):H(2)O(2) Ratio and Confers Anoikis Resistance to Tumors
-
Zhu P, Tan MJ, Huang RL, Tan CK, Chong HC, Pal M, Lam CR, Boukamp P, Pan JY, Tan SH, Kersten S, Li HY, Ding JL and Tan NS. Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O(2)(-):H(2)O(2) Ratio and Confers Anoikis Resistance to Tumors. Cancer Cell. 2011; 19:401-415.
-
(2011)
Cancer Cell.
, vol.19
, pp. 401-415
-
-
Zhu, P.1
Tan, M.J.2
Huang, R.L.3
Tan, C.K.4
Chong, H.C.5
Pal, M.6
Lam, C.R.7
Boukamp, P.8
Pan, J.Y.9
Tan, S.H.10
Kersten, S.11
Li, H.Y.12
Ding, J.L.13
Tan, N.S.14
-
49
-
-
84903204012
-
PPARbeta/delta activation of CD300a controls intestinal immunity
-
Tanaka T, Tahara-Hanaoka S, Nabekura T, Ikeda K, Jiang S, Tsutsumi S, Inagaki T, Magoori K, Higurashi T, Takahashi H, Tachibana K, Tsurutani Y, Raza S, Anai M, Minami T, Wada Y, et al. PPARbeta/delta activation of CD300a controls intestinal immunity. Sci Rep. 2014; 4:5412.
-
(2014)
Sci Rep
, vol.4
, pp. 5412
-
-
Tanaka, T.1
Tahara-Hanaoka, S.2
Nabekura, T.3
Ikeda, K.4
Jiang, S.5
Tsutsumi, S.6
Inagaki, T.7
Magoori, K.8
Higurashi, T.9
Takahashi, H.10
Tachibana, K.11
Tsurutani, Y.12
Raza, S.13
Anai, M.14
Minami, T.15
Wada, Y.16
-
50
-
-
0023902548
-
Enhancement of c-fos expression is associated with activated macrophages
-
Higuchi Y, Setoguchi M, Yoshida S, Akizuki S and Yamamoto S. Enhancement of c-fos expression is associated with activated macrophages. Oncogene. 1988; 2:515-521.
-
(1988)
Oncogene.
, vol.2
, pp. 515-521
-
-
Higuchi, Y.1
Setoguchi, M.2
Yoshida, S.3
Akizuki, S.4
Yamamoto, S.5
-
51
-
-
84868584901
-
G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly
-
Wiezlak M, Diring J, Abella J, Mouilleron S, Way M, McDonald NQ and Treisman R. G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly. J Cell Sci. 2012; 125:5860-5872.
-
(2012)
J Cell Sci.
, vol.125
, pp. 5860-5872
-
-
Wiezlak, M.1
Diring, J.2
Abella, J.3
Mouilleron, S.4
Way, M.5
McDonald, N.Q.6
Treisman, R.7
-
52
-
-
84860169530
-
MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer
-
Zhang Y, Wang Z, Chen M, Peng L, Wang X, Ma Q, Ma F and Jiang B. MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. Mol Cancer. 2012; 11:23.
-
(2012)
Mol Cancer
, vol.11
, pp. 23
-
-
Zhang, Y.1
Wang, Z.2
Chen, M.3
Peng, L.4
Wang, X.5
Ma, Q.6
Ma, F.7
Jiang, B.8
-
53
-
-
79951949654
-
PRSS14/Epithin is induced in macrophages by the IFN-gamma/JAK/STAT pathway and mediates transendothelial migration
-
Lee D, Lee HS, Yang SJ, Jeong H, Kim DY, Lee SD, Oh JW, Park D and Kim MG. PRSS14/Epithin is induced in macrophages by the IFN-gamma/JAK/STAT pathway and mediates transendothelial migration. Biochem Biophys Res Commun. 2011; 405:644-650.
-
(2011)
Biochem Biophys Res Commun.
, vol.405
, pp. 644-650
-
-
Lee, D.1
Lee, H.S.2
Yang, S.J.3
Jeong, H.4
Kim, D.Y.5
Lee, S.D.6
Oh, J.W.7
Park, D.8
Kim, M.G.9
-
54
-
-
0034727104
-
LDLreceptor- related proteins in Wnt signal transduction
-
Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP and He X. LDLreceptor- related proteins in Wnt signal transduction. Nature. 2000; 407:530-535.
-
(2000)
Nature.
, vol.407
, pp. 530-535
-
-
Tamai, K.1
Semenov, M.2
Kato, Y.3
Spokony, R.4
Liu, C.5
Katsuyama, Y.6
Hess, F.7
Saint-Jeannet, J.P.8
He, X.9
-
55
-
-
80052782624
-
Wnt pathway activation, cell migration, and lipid uptake is regulated by low-density lipoprotein receptor-related protein 5 in human macrophages
-
Borrell-Pages M, Romero JC, Juan-Babot O and Badimon L. Wnt pathway activation, cell migration, and lipid uptake is regulated by low-density lipoprotein receptor-related protein 5 in human macrophages. Eur Heart J. 2011; 32:2841-2850.
-
(2011)
Eur Heart J.
, vol.32
, pp. 2841-2850
-
-
Borrell-Pages, M.1
Romero, J.C.2
Juan-Babot, O.3
Badimon, L.4
-
56
-
-
84860389289
-
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
-
Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G and Brugge JS. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes Dev. 2011; 25:1716-1733.
-
(2011)
Genes Dev.
, vol.25
, pp. 1716-1733
-
-
Grassian, A.R.1
Metallo, C.M.2
Coloff, J.L.3
Stephanopoulos, G.4
Brugge, J.S.5
-
57
-
-
84555186674
-
Development of Improved PPARbeta/ delta Inhibitors
-
Toth PM, Naruhn S, Pape VF, Dörr SM, Klebe G, Müller R and Diederich WE. Development of Improved PPARbeta/ delta Inhibitors. ChemMedChem. 2012; 7:159-170.
-
(2012)
ChemMedChem.
, vol.7
, pp. 159-170
-
-
Toth, P.M.1
Naruhn, S.2
Pape, V.F.3
Dörr, S.M.4
Klebe, G.5
Müller, R.6
Diederich, W.E.7
-
58
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R and Evans RM. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002; 99:303-308.
-
(2002)
Proc Natl Acad Sci U S A.
, vol.99
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
Ong, E.S.4
Nelson, M.C.5
Olefsky, J.M.6
Boland, R.7
Evans, R.M.8
-
59
-
-
4043070783
-
Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain
-
Hayashi S, Lewis P, Pevny L and McMahon AP. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mech Dev. 2002; 119 Suppl 1:S97-S101.
-
(2002)
Mech Dev.
, vol.119
, pp. S97-S101
-
-
Hayashi, S.1
Lewis, P.2
Pevny, L.3
McMahon, A.P.4
-
60
-
-
84877603089
-
PPARbeta/delta governs Wnt signaling and bone turnover
-
Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Bohm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, et al. PPARbeta/delta governs Wnt signaling and bone turnover. Nat Med. 2013:19.
-
(2013)
Nat Med.
, pp. 19
-
-
Scholtysek, C.1
Katzenbeisser, J.2
Fu, H.3
Uderhardt, S.4
Ipseiz, N.5
Stoll, C.6
Zaiss, M.M.7
Stock, M.8
Donhauser, L.9
Bohm, C.10
Kleyer, A.11
Hess, A.12
Engelke, K.13
David, J.P.14
Djouad, F.15
Tuckermann, J.P.16
-
61
-
-
2442726683
-
Tissue-specific, cell cycleregulated chimeric transcription factors for the targeting of gene expression to tumor cells
-
Jérôme V and Müller R. Tissue-specific, cell cycleregulated chimeric transcription factors for the targeting of gene expression to tumor cells. Hum Gene Ther. 1998; 9:2653-2659.
-
(1998)
Hum Gene Ther.
, vol.9
, pp. 2653-2659
-
-
Jérôme, V.1
Müller, R.2
-
62
-
-
84860903681
-
Implementing an online tool for genome-wide validation of survivalassociated biomarkers in ovarian-cancer using microarray data from 1287 patients
-
Gyorffy B, Lanczky A and Szallasi Z. Implementing an online tool for genome-wide validation of survivalassociated biomarkers in ovarian-cancer using microarray data from 1287 patients. Endocr Relat Cancer. 2012; 19:197-208.
-
(2012)
Endocr Relat Cancer.
, vol.19
, pp. 197-208
-
-
Gyorffy, B.1
Lanczky, A.2
Szallasi, Z.3
|