Molecular links between tumor angiogenesis and inflammation: Inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy

Cancer Science

Volumn 99, Issue 8, 2008, Pages 1501-1506

  Ono, Mayumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLODRONIC ACID; CYCLOOXYGENASE 2 INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PROTEINASE; VASCULOTROPIN A;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; CANCER CELL; CANCER GROWTH; CANCER THERAPY; CELL INFILTRATION; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINE PRODUCTION; DRUG TARGETING; ENZYME ACTIVATION; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MACROPHAGE INFILTRATION; MACROPHAGE MIGRATION; MALIGNANT TRANSFORMATION; METASTASIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TUMOR ANGIOGENESIS; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; CHEMOKINES; CYCLOOXYGENASE 2 INHIBITORS; HUMANS; INFLAMMATION; INTERLEUKIN-8; MACROPHAGES; MATRIX METALLOPROTEINASES; MICE; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PROSTAGLANDINS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR AP-1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 49749124618     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00853.x     Document Type: Review

References (39)

1. Coussens L, Werb Z. Inflammation and cancer. Nature 2002; 420: 860-7.
2. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2005; 6: 389-95.
3. Charo IF, Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 2006; 354: 610-21.
4. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-64.
5. Costa C, Incio J, Soares R. Angiogenesis and chronic inflammation: Cause or consequence? Angiogenesis 2007; 10: 149-66.
6. Lin W-W, Karin M. A cytokine-mediated link between inmate immunity, inflammation, and cancer. J Clinic Invest 2007; 117: 1175-82.
7. Sica A, Schioppa T, Mantovani A et al. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 2006; 42: 717-27.
8. Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 2006; 97: 439-47.
9. Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction: Tumor development. J Clinic Invest 2007; 117: 1155-65.
10. Balkwill F, Mantovani A. Inflammation and cancer. Back to Virchow? Lancet 2001; 357: 539-45.
11. Kuwano M, Basaki Y, Kuwano T et al. The critical role of inflammatory cell infiltration in tumor angiogenesis: A target for anti-tumor drug development? In:
12. Zubar RV, ed. New Angiogenesis Research. New York: Nova Science Publishers, 2005; 157-70.
13. Pollard JW. Tumor-educated macrophages promote tumor progression and metastasis. Nat Rev Cancer 2004; 4: 71-8.
14. Leek RD, Lewis CE, Whitehouse R et al. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 1996; 56: 4625-9.
15. Leek RD et al. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res 2002; 62: 1326-9.
16. Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies. J Pathol 2002; 196: 254-65.
17. Nishie A, Ono M, Shono T et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human glioma. Clin Cancer Res 1999; 5: 1107-13.
18. Torisu H, Ono M, Kiryu H et al. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNF-α and IL-1α. Int J Cancer 2000; 85: 182-8.
19. Mantovani A, Sozzani S, Locati M et al. A macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23: 549-55.
20. Mantovani A et al. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 2004; 25: 677-86.
21. Ueno T, Masakazu T, Saji H et al. Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis and survival in human breast cancer. Clin Cancer Res 2000; 6: 3282-9.
22. Goede V, Brogelli L, Ziche M et al. Induction of inflammatory angiogenesis by monocyte chemoattractant protein-1. Int J Cancer 1999; 82: 765-70.
23. Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006; 66: 605-12.
24. Ogawa S, Yoshida S, Ono M et al. Induction of macrophage inflammatory protein-1alpha and vascular endothelial growth factor during inflammatory neovascularization in the mouse cornea. Angiogenesis 1999; 314: 327-34.
25. Ryuto M, Ono M, Izumi H et al. Induction of vascular endothelial growth factor by tumor necrosis factor-α in human glioma cells: Possible roles of SP-1. J Biol Chem 1996; 271: 28.220-8.
26. Shono T, Ono M, Izumi H et al. Involvement of a transcription factor NF-κB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol Cell Biol 1996; 16: 4231-9.
27. Yoshida S, Ono M, Shono T et al. Involvement of interleukin-8, vascular endothelial growth factor and basic fibroblast growth factor in tumor necrosis factor-α dependent angiogenesis. Mol Cell Biol 1997; 17: 4015-23.
28. Saijo Y, Tanaka M, Miki M et al. Proinflammatory cytokine IL-1 beta promotes tumor growth of Lewis lung carcinoma by induction of angiogenic factors: In vivo analysis of tumor-stromal interaction. J Immunol 2002; 169: 469-75.
29. Voronov E, Shouval DS, Krelin Y et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 2003; 100: 2645-50.
30. Song X, Voronov E, Dvorkin T et al. Differential effects of IL-1α and IL-1β on tumorigenicity patterns and invasiveness. J Immunol 2003; 171: 6448-56.
31. Yano S, Nokihara H, Yamamoto A et al. Multifunctional interleukin-1β promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion-, invasion- and angiogenesis-related molecules. Cancer Sci 2003; 94: 244-52.
32. Masferrer JL, Koki A, Seibert K. COX-2 inhibitors. A new class of antiangiogenic agents. Ann NY Acad Sci 1999; 889: 84-6.
33. Sawaoka H, Tsuji S, Tsuijii M et al. Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo. Laboratory Invest 1999; 79: 1469-77.
34. Kuwano T, Nakao S, Yamamoto H et al. Cyclooxygenase 2 is a key enzyme for inflammatory cytokinase-induced angiogenesis. FASEB J 2004; 18: 300-10.
35. Nakao S, Kuwano T, Tsutsumi-Miyahara C et al. Infiltration of COX2-expressing macrophage is prerequisite for IL-1beta-induced neovascularization and tumor growth. J Clinic Invest 2005; 115: 2979-91.
36. Nakao S, Hata Y, Miura M et al. Dexamethasone inhibits IL-1β-induced corneal neovascularization; role of NF-κB-activated stromal cells in inflammatory angiogenesis. Am J Path 2007; 171: 1058-65.
37. Van Rooijen N. The liposome-mediated macrophage 'suicide'technique. J Immunol Meth 1989; 124: 1-6.
38. Kimura Y, Watari K, Fotovati A et al. Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis. Cancer Sci 2007; 98: 2009-18.
39. Hiraoka K, Zenmyo M, Watari K et al. Inhibition of bone and muscle metastasis of lung cancer cells by decrease in the number of monocytesl macrophages. Cancer Sci 2008; in press.