Mollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 247-254

  Zhang, Li ^a   Wang, Handong ^a   Zhu, Jianhong ^a   Xu, Jianguo ^a   Ding, Ke ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; ERK; Mollugin; PI3K AKT mTOR p70S6K

Indexed keywords

ANTINEOPLASTIC AGENT; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MOLLUGIN; NATURAL PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER MODEL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; RUBIA CORDIFOLIA; SIGNAL TRANSDUCTION;

RUBIA CORDIFOLIA;

APOPTOSIS; AUTOPHAGY; ERK; MOLLUGIN; PI3K/AKT/MTOR/P70S6K;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; NEOPLASMS, EXPERIMENTAL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRANS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TOR SERINE-THREONINE KINASES;

EID: 84904755420     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.101     Document Type: Article

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