-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352: 987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
2
-
-
0037842147
-
Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme: Eastern Cooperative Oncology Group Trial 2394
-
Grossman SA, O'Neill A, Grunnet M, et al. Phase III study comparing three cycles of infusional carmustine and cisplatin followed by radiation therapy with radiation therapy and concurrent carmustine in patients with newly diagnosed supratentorial glioblastoma multiforme: Eastern Cooperative Oncology Group Trial 2394. J Clin Oncol 2003;21:1485-91.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1485-1491
-
-
Grossman, S.A.1
O'Neill, A.2
Grunnet, M.3
-
3
-
-
1042301341
-
Factors influencing survival in high-grade gliomas
-
Buckner JC. Factors influencing survival in high-grade gliomas. Semin Oncol 2003;30:10-4.
-
(2003)
Semin Oncol
, vol.30
, pp. 10-14
-
-
Buckner, J.C.1
-
4
-
-
0027294649
-
Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials
-
Curran WJ, Jr., Scott CB, Norton J, et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst 1993;85:704-10.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 704-710
-
-
Curran Jr., W.J.1
Scott, C.B.2
Norton, J.3
-
5
-
-
0033897173
-
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung WK, Albright RE, Olson J, et al. A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 2000;83:588-93.
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.K.1
Albright, R.E.2
Olson, J.3
-
6
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol 1999;17:2572-8.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2572-2578
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
-
7
-
-
0038737156
-
Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma
-
Salmaggi A, Eoli M, Frigerio S, et al. Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma. J Neurooncol 2003;62:297-303.
-
(2003)
J Neurooncol
, vol.62
, pp. 297-303
-
-
Salmaggi, A.1
Eoli, M.2
Frigerio, S.3
-
8
-
-
0037389767
-
Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A
-
Lamszus K, Ulbricht U, Matschke J, Brockmann MA, Filibrandt R, Westphal M. Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A. Clin Cancer Res 2003;9:1399-405.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1399-1405
-
-
Lamszus, K.1
Ulbricht, U.2
Matschke, J.3
Brockmann, M.A.4
Filibrandt, R.5
Westphal, M.6
-
9
-
-
33749028188
-
Vascular endothelial growth factor signaling pathways: Therapeutic perspective
-
Kowanetz M, Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006;12:5018-22.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5018-5022
-
-
Kowanetz, M.1
Ferrara, N.2
-
11
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-9.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
-
12
-
-
0142157702
-
Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes
-
Godard S, Getz G, Delorenzi M, et al. Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. Cancer Res 2003;63:6613-25.
-
(2003)
Cancer Res
, vol.63
, pp. 6613-6625
-
-
Godard, S.1
Getz, G.2
Delorenzi, M.3
-
13
-
-
0035688408
-
Monoclonal antibodies to vascular endothelial growth factor (VEGF) and the VEGF receptor, FLT-1, inhibit the growth of C6 glioma in a mouse xenograft
-
Stefanik DF, Fellows WK, Rizkalla LR, et al. Monoclonal antibodies to vascular endothelial growth factor (VEGF) and the VEGF receptor, FLT-1, inhibit the growth of C6 glioma in a mouse xenograft. J Neurooncol 2001;55:91-100.
-
(2001)
J Neurooncol
, vol.55
, pp. 91-100
-
-
Stefanik, D.F.1
Fellows, W.K.2
Rizkalla, L.R.3
-
14
-
-
0242468884
-
A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer
-
Cobleigh MA, Langmuir VK, Sledge GW, et al. A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer. Semin Oncol 2003;30:117-24.
-
(2003)
Semin Oncol
, vol.30
, pp. 117-124
-
-
Cobleigh, M.A.1
Langmuir, V.K.2
Sledge, G.W.3
-
15
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
16
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003;349:427-34.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
17
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343:905-14.
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
-
18
-
-
0032945307
-
Irinotecan therapy in adults with recurrent or progressive malignant glioma
-
Friedman HS, Petros WP, Friedman AH, et al. Irinotecan therapy in adults with recurrent or progressive malignant glioma. J Clin Oncol 1999;17:1516-25.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1516-1525
-
-
Friedman, H.S.1
Petros, W.P.2
Friedman, A.H.3
-
19
-
-
0037403422
-
Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen
-
Cloughesy TF, Filka E, Kuhn J, et al. Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen. Cancer 2003;97:2381-6.
-
(2003)
Cancer
, vol.97
, pp. 2381-2386
-
-
Cloughesy, T.F.1
Filka, E.2
Kuhn, J.3
-
20
-
-
0036204758
-
Salvage chemotherapy with CPT-11 for recurrent glioblastoma multiforme
-
Chamberlain MC. Salvage chemotherapy with CPT-11 for recurrent glioblastoma multiforme. J Neurooncol 2002;56:183-8.
-
(2002)
J Neurooncol
, vol.56
, pp. 183-188
-
-
Chamberlain, M.C.1
-
21
-
-
33744477354
-
A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: A North American Brain Tumor Consortium study
-
Prados MD, Lamborn K, Yung WK, et al. A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study. Neurooncol 2006;8:189-93.
-
(2006)
Neurooncol
, vol.8
, pp. 189-193
-
-
Prados, M.D.1
Lamborn, K.2
Yung, W.K.3
-
22
-
-
0942266258
-
Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: Final report of NABTT 97-11
-
Batchelor TT, Gilbert MR, Supko JG, et al. Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11. Neurooncol 2004;6:21-7.
-
(2004)
Neurooncol
, vol.6
, pp. 21-27
-
-
Batchelor, T.T.1
Gilbert, M.R.2
Supko, J.G.3
-
23
-
-
32944482137
-
Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma
-
May;
-
Stark-Vance V. Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma. In: World Federation of Neuro-Oncology Meeting; 2005 May; 2005. p. 91.
-
(2005)
World Federation of Neuro-Oncology Meeting
, pp. 91
-
-
Stark-Vance, V.1
-
24
-
-
0036676381
-
Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report
-
Kuhn JG. Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report. Oncology (Huntingt) 2002;16:33-40.
-
(2002)
Oncology (Huntingt)
, vol.16
, pp. 33-40
-
-
Kuhn, J.G.1
-
25
-
-
0025281789
-
Response criteria for phase II studies of supratentorial malignant glioma
-
Macdonald DR, Cascino TL, Schold SC, Jr., Cairncross JG. Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 1990; 8:1277-80.
-
(1990)
J Clin Oncol
, vol.8
, pp. 1277-1280
-
-
Macdonald, D.R.1
Cascino, T.L.2
Schold Jr., S.C.3
Cairncross, J.G.4
-
26
-
-
0032421559
-
Multi-drug versus single agent chemotherapy for high grade astrocytoma: Results of a meta-analysis
-
Huncharek M, Muscat J, Geschwind JF. Multi-drug versus single agent chemotherapy for high grade astrocytoma: results of a meta-analysis. Anticancer Res 1998;18:4693-7.
-
(1998)
Anticancer Res
, vol.18
, pp. 4693-4697
-
-
Huncharek, M.1
Muscat, J.2
Geschwind, J.F.3
-
27
-
-
0036185863
-
Pre-irradiation semi-intensive chemotherapy with carboplatin and cyclophosphamide in malignant glioma: A phase II study
-
Vinolas N, Gil M, Verger E, et al. Pre-irradiation semi-intensive chemotherapy with carboplatin and cyclophosphamide in malignant glioma: a phase II study. Anticancer Drugs 2002;13:163-7.
-
(2002)
Anticancer Drugs
, vol.13
, pp. 163-167
-
-
Vinolas, N.1
Gil, M.2
Verger, E.3
-
28
-
-
0034255417
-
The risk of venous thromboembolism is increased throughout the course of malignant glioma: An evidence-based review
-
Marras LC, Geerts WH, Perry JR. The risk of venous thromboembolism is increased throughout the course of malignant glioma: an evidence-based review. Cancer 2000;89:640-6.
-
(2000)
Cancer
, vol.89
, pp. 640-646
-
-
Marras, L.C.1
Geerts, W.H.2
Perry, J.R.3
-
29
-
-
0031418172
-
Incidence of risk of thromboembolism during treatment high-grade gliomas: A prospective study
-
Brandes AA, Scelzi E, Salmistraro G, et al. Incidence of risk of thromboembolism during treatment high-grade gliomas: a prospective study. Eur J Cancer 1997;33:1592-6.
-
(1997)
Eur J Cancer
, vol.33
, pp. 1592-1596
-
-
Brandes, A.A.1
Scelzi, E.2
Salmistraro, G.3
-
31
-
-
0033954292
-
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
-
Fine HA, Figg WD, Jaeckle K, et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 2000;18: 708-15.
-
(2000)
J Clin Oncol
, vol.18
, pp. 708-715
-
-
Fine, H.A.1
Figg, W.D.2
Jaeckle, K.3
-
32
-
-
0037811745
-
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas
-
Fine HA, Wen PY, Maher EA, et al. Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. J Clin Oncol 2003;21: 2299-304.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2299-2304
-
-
Fine, H.A.1
Wen, P.Y.2
Maher, E.A.3
-
33
-
-
33947282300
-
-
Conrad C, Friedman HS, Reardon DA, et al. A phase I/II trial of single agent PTK 787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM). 2004 ASCO Annual Meeting Proceedings (Post-Meeting Edition). J Clin Oncol 2004;22(14S; July 15 Supplement):1512.
-
Conrad C, Friedman HS, Reardon DA, et al. A phase I/II trial of single agent PTK 787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in patients with recurrent glioblastoma multiforme (GBM). 2004 ASCO Annual Meeting Proceedings (Post-Meeting Edition). J Clin Oncol 2004;22(14S; July 15 Supplement):1512.
-
-
-
-
34
-
-
16844371774
-
A phase I/II trial of PTK787/ZK 22584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM) [abstract 1513]
-
Reardon DA, Friedman HS, Yung WK, et al. A phase I/II trial of PTK787/ZK 22584 (PTK/ZK), a novel, oral angiogenesis inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM) [abstract 1513]. Proc Am Soc Clin Oncol 2004;23:110.
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 110
-
-
Reardon, D.A.1
Friedman, H.S.2
Yung, W.K.3
-
35
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
Rich JN, Reardon DA, Peery T, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 2004; 22:133-42.
-
(2004)
J Clin Oncol
, vol.22
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
-
36
-
-
31544474851
-
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
Prados MD, Lamborn KR, Chang S, et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neurooncol 2006;8:67-78.
-
(2006)
Neurooncol
, vol.8
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
-
37
-
-
33646555670
-
Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas [abstract 1504]
-
Fine HA, Kim L, Royce C, et al. Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas [abstract 1504]. J Clin Oncol 2005;23:115.
-
(2005)
J Clin Oncol
, vol.23
, pp. 115
-
-
Fine, H.A.1
Kim, L.2
Royce, C.3
-
38
-
-
25644449640
-
Pathophysiological consequences of VEGF-induced vascular permeability
-
Weis SM, Cheresh DA. Pathophysiological consequences of VEGF-induced vascular permeability. Nature 2005;437:497-504.
-
(2005)
Nature
, vol.437
, pp. 497-504
-
-
Weis, S.M.1
Cheresh, D.A.2
-
39
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S, Wu Q, Sathornsumetee S, et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 2006; 66:7843-8.
-
(2006)
Cancer Res
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
-
40
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal ancer
-
Willett CG, Boucher Y, di Tomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal ancer. Nat Med 2004;10:145-7.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
di Tomaso, E.3
-
41
-
-
0032987731
-
Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability
-
Wu HM, Yuan Y, Zawieja DC, Tinsley J, Granger HJ. Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability. Am J Physiol 1999;276:H535-42.
-
(1999)
Am J Physiol
, vol.276
-
-
Wu, H.M.1
Yuan, Y.2
Zawieja, D.C.3
Tinsley, J.4
Granger, H.J.5
-
43
-
-
0031825437
-
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
-
Esser S, Lampugnani MG, Corada M, Dejana E, Risau W. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J Cell Sci 1998;111:1853-65.
-
(1998)
J Cell Sci
, vol.111
, pp. 1853-1865
-
-
Esser, S.1
Lampugnani, M.G.2
Corada, M.3
Dejana, E.4
Risau, W.5
-
44
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
45
-
-
19944422751
-
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
-
Winkler F, Kozin SV, Tong RT, et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004;6:553-63.
-
(2004)
Cancer Cell
, vol.6
, pp. 553-563
-
-
Winkler, F.1
Kozin, S.V.2
Tong, R.T.3
-
46
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
Tong RT, Boucher Y, Kozin SV, Winkler F, Hicklin DJ, Jain RK. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res 2004;64:3731-6.
-
(2004)
Cancer Res
, vol.64
, pp. 3731-3736
-
-
Tong, R.T.1
Boucher, Y.2
Kozin, S.V.3
Winkler, F.4
Hicklin, D.J.5
Jain, R.K.6
|