-
1
-
-
0033911488
-
Inflamm-aging: An evolutionaryperspective on immunosenescence
-
Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging: an evolutionaryperspective on immunosenescence. Ann N Y Acad Sci 2000; 908:244-254
-
(2000)
Ann N y Acad Sci
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
-
2
-
-
16344376370
-
Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity
-
DOI 10.1016/j.febslet.2005.02.055
-
De Martinis M, Franceschi C, Monti D, Ginaldi L. Inflamm-aging and lifelongantigenic load as major determinants of aging rate and longevity. FEBS Lett2005; 579:2035-2039 (Pubitemid 40469666)
-
(2005)
FEBS Letters
, vol.579
, Issue.10
, pp. 2035-2039
-
-
De Martinis, M.1
Franceschi, C.2
Monti, D.3
Ginaldi, L.4
-
3
-
-
80054865578
-
-
Fulop T, Franceschi C,Hirokawa K and Pawelec G, editors The Netherlands: Springer Science\+BusinessMedia B.V
-
Bucci L, Ostan R, Capri S, et al. Inflamm-aging: handbook on immunosenesce-basic understanding and clinical applications. 1. In: Fulop T, Franceschi C,Hirokawa K and Pawelec G, editors. The Netherlands: Springer Science\+BusinessMedia B.V; 2009. pp. 893-918
-
(2009)
Inflamm-Aging: Handbook on Immunosenesce-Basic Understanding and Clinical Applications
, vol.1
, pp. 893-918
-
-
Bucci, L.1
Ostan, R.2
Capri, S.3
-
4
-
-
33846111415
-
Inflammaging and anti-inflammaging: A systemic perspective on aging and longevity emerged from studies in humans
-
DOI 10.1016/j.mad.2006.11.016, PII S0047637406002491, Functional Genomics of Aging III
-
Franceschi C, Capri M, Monti D, et al. Inflamm-aging and antiinflamm-aging: asystemic perspective on aging and longevity emerged from studies in humans.Mech Aging Dev 2007; 128:92-105 (Pubitemid 46073065)
-
(2007)
Mechanisms of Ageing and Development
, vol.128
, Issue.1
, pp. 92-105
-
-
Franceschi, C.1
Capri, M.2
Monti, D.3
Giunta, S.4
Olivieri, F.5
Sevini, F.6
Panourgia, M.P.7
Invidia, L.8
Celani, L.9
Scurti, M.10
Cevenini, E.11
Castellani, G.C.12
Salvioli, S.13
-
5
-
-
0037396614
-
Centenarians as a model for healthy aging
-
DOI 10.1042/BST0310457
-
Franceschi C, Bonafe M. Centenarians as a model for healthy aging. BiochemSoc Trans 2003; 31:457-461 (Pubitemid 36520700)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.2
, pp. 457-461
-
-
Franceschi, C.1
Bonafe, M.2
-
7
-
-
77950254226
-
Systems biology and longevity: Anemerging approach to identify innovative antiaging targets and strategies
-
Cevenini E, Bellavista E, Tieri P, et al. Systems biology and longevity: anemerging approach to identify innovative antiaging targets and strategies.Curr Pharm Des 2010; 16:802-813
-
(2010)
Curr Pharm des
, vol.16
, pp. 802-813
-
-
Cevenini, E.1
Bellavista, E.2
Tieri, P.3
-
8
-
-
40949123149
-
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
-
DOI 10.1016/j.arr.2007.09.002, PII S1568163707000566
-
Salminen A, Huuskonen J, Ojala J, et al. Activation of innate immunity systemduring aging: NF-kB signaling is the molecular culprit of inflamm-aging. AgingRes Rev 2008; 7:83-105 (Pubitemid 351418294)
-
(2008)
Ageing Research Reviews
, vol.7
, Issue.2
, pp. 83-105
-
-
Salminen, A.1
Huuskonen, J.2
Ojala, J.3
Kauppinen, A.4
Kaarniranta, K.5
Suuronen, T.6
-
10
-
-
79951912532
-
Four faces of cellular senescence
-
Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol 2011;192:547-556
-
(2011)
J Cell Biol
, vol.192
, pp. 547-556
-
-
Rodier, F.1
Campisi, J.2
-
11
-
-
0027970713
-
1 arrest and long-term induction of Cip1 in normal human fibroblasts
-
Di Leonardo A, Linke SP, Clarkin K, Wahl GM. DNA damage triggers aprolonged p53-dependent G1 arrest and long-term induction of Cip1 innormal human fibroblasts. Genes Dev 1994; 8:2540-2551 (Pubitemid 24347245)
-
(1994)
Genes and Development
, vol.8
, Issue.21
, pp. 2540-2551
-
-
Di Leonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
12
-
-
68249096784
-
Persistent DNA damage signalling triggerssenescence-associated inflammatory cytokine secretion
-
Rodier F, Coppé JP, Patil CK, et al. Persistent DNA damage signalling triggerssenescence-associated inflammatory cytokine secretion. Nat Cell Biol 2009;11:973-979
-
(2009)
Nat Cell Biol
, vol.11
, pp. 973-979
-
-
Rodier, F.1
Coppé, J.P.2
Patil, C.K.3
-
13
-
-
78651104478
-
DNA-SCARS: Distinct nuclearstructures that sustain damage-induced senescence growth arrest andinflammatory cytokine secretion
-
Rodier F, Muñ oz DP, Teachenor R, et al. DNA-SCARS: distinct nuclearstructures that sustain damage-induced senescence growth arrest andinflammatory cytokine secretion. J Cell Sci 2011; 124:68-81
-
(2011)
J Cell Sci
, vol.124
, pp. 68-81
-
-
Rodier, F.1
Muñoz, D.P.2
Teachenor, R.3
-
14
-
-
70350125106
-
Cell surface-bound IL-1a is anupstream regulator of the senescence-associated IL-6/IL-8 cytokine network
-
Orjalo AV, Bhaumik D, Gengler BK, et al. Cell surface-bound IL-1a is anupstream regulator of the senescence-associated IL-6/IL-8 cytokine network.Proc Natl Acad Sci USA 2009; 106:17031-17036
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17031-17036
-
-
Orjalo, A.V.1
Bhaumik, D.2
Gengler, B.K.3
-
15
-
-
44649120132
-
Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
-
DOI 10.1016/j.cell.2008.03.038, PII S0092867408006193
-
Acosta JC, O'Loghlen A, Banito A, et al. Chemokine signaling via the CXCR2receptor reinforces senescence. Cell 2008; 133:1006-1018 (Pubitemid 351795610)
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1006-1018
-
-
Acosta, J.C.1
O'Loghlen, A.2
Banito, A.3
Guijarro, M.V.4
Augert, A.5
Raguz, S.6
Fumagalli, M.7
Da Costa, M.8
Brown, C.9
Popov, N.10
Takatsu, Y.11
Melamed, J.12
D'Adda Di Fagagna, F.13
Bernard, D.14
Hernando, E.15
Gil, J.16
-
16
-
-
44649101304
-
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
-
DOI 10.1016/j.cell.2008.03.039, PII S009286740800620X
-
Kuilman T, Michaloglou C, Vredeveld LCW, et al. Oncogene induced senescencerelayed by an interleukin-dependent inflammatory network. Cell 2008;133:1019-1031 (Pubitemid 351787746)
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.W.3
Douma, S.4
Van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
17
-
-
77952105389
-
Inflammatory networks duringcellular senescence: Causes and consequences
-
Freund A, Orjalo AV, Desprez PY, Campisi J. Inflammatory networks duringcellular senescence: causes and consequences. Trends Mol Med 2010;16:238-246
-
(2010)
Trends Mol Med
, vol.16
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
18
-
-
67649318940
-
MicroRNAs miR-146a/b negativelymodulate the senescence-associated inflammatory mediators IL-6 and IL-8
-
Bhaumik D, Scott GK, Schokrpur S, et al. MicroRNAs miR-146a/b negativelymodulate the senescence-associated inflammatory mediators IL-6 and IL-8.Aging 2009; 1:402-411
-
(2009)
Aging
, vol.1
, pp. 402-411
-
-
Bhaumik, D.1
Scott, G.K.2
Schokrpur, S.3
-
19
-
-
84871926464
-
MiR-146a as marker of senescenceassociatedpro-inflammatory status in cells involved in vascular remodelling
-
Epub ahead of print] PubMed PMID:22692818
-
Olivieri F, Lazzarini R, Recchioni R, et al. MiR-146a as marker of senescenceassociatedpro-inflammatory status in cells involved in vascular remodelling.Age (Dordr) 2012; [Epub ahead of print] PubMed PMID:22692818
-
(2012)
Age (Dordr)
-
-
Olivieri, F.1
Lazzarini, R.2
Recchioni, R.3
-
20
-
-
33747608638
-
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
DOI 10.1073/pnas.0605298103
-
Taganov KD, Boldin MP. Chang KJ, and Baltimore D. NF-kappaB dependentinduction of microRNA miR-146, an inhibitor targeted to signaling proteins ofinnate immune responses. Proc Natl Acad Sci USA 2006; 103:12481-12486 (Pubitemid 44267285)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.33
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.-J.3
Baltimore, D.4
-
21
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
DOI 10.1038/nrm2233, PII NRM2233
-
Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad thingshappen to good cells. Nat Rev Mol Cell Biol 2007; 8:729-740 (Pubitemid 47312822)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
22
-
-
0042734423
-
The role of chondrocyte senescence inosteoarthritis
-
Price JS, Waters JG, Darrah C, et al. The role of chondrocyte senescence inosteoarthritis. Aging Cell 2002; 1:57-65
-
(2002)
Aging Cell
, vol.1
, pp. 57-65
-
-
Price, J.S.1
Waters, J.G.2
Darrah, C.3
-
23
-
-
0035130153
-
Differential expression of thymosin β-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: Evidence for senescent endothelial cells in vivo at sites of atherosclerosis
-
DOI 10.1096/fj.00-0051com
-
Vasile E, Tomita Y, Brown LF, et al. Differential expression of thymosin beta-10by early passage and senescent vascular endothelium is modulated byVPF/VEGF: evidence for senescent endothelial cells in vivo at sites ofatherosclerosis. FASEB J 2001; 15:458-466 (Pubitemid 32141437)
-
(2001)
FASEB Journal
, vol.15
, Issue.2
, pp. 458-466
-
-
Vasile, E.1
Tomita, Y.2
Brown, L.F.3
Kocher, O.4
Dvorak, H.F.5
-
24
-
-
26244436644
-
SA β Gal staining: Biomarker or delusion
-
DOI 10.1016/j.exger.2005.08.005, PII S0531556505001932
-
Cristofalo VJ. SA beta Gal staining: biomarker or delusion. Exp Gerontol2005; 40:836-838 (Pubitemid 41416547)
-
(2005)
Experimental Gerontology
, vol.40
, Issue.10
, pp. 836-838
-
-
Cristofalo, V.J.1
-
25
-
-
80053531658
-
Regulation of cancer stem cells by cytokinenetworks: Attacking cancer's inflammatory roots
-
Korkaya H, Liu S, Wicha MS. Regulation of cancer stem cells by cytokinenetworks: attacking cancer's inflammatory roots. Clin Cancer Res 2011;17:6125-6129
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6125-6129
-
-
Korkaya, H.1
Liu, S.2
Wicha, M.S.3
-
26
-
-
80052358980
-
Therapeutic strategies for the clinicalblockade of IL-6/gp130 signaling
-
Jones SA, Scheller J, Rose-John S. Therapeutic strategies for the clinicalblockade of IL-6/gp130 signaling. J Clin Invest 2011; 121:3375-3383
-
(2011)
J Clin Invest
, vol.121
, pp. 3375-3383
-
-
Jones, S.A.1
Scheller, J.2
Rose-John, S.3
-
27
-
-
83555177230
-
Inflamm-aging of the stem cell niche:Breast cancer as a paradigmatic example: Breakdown of the multishellcytokine network fuels cancer in aged people
-
Bonafè M, Storci G, Franceschi C. Inflamm-aging of the stem cell niche:Breast cancer as a paradigmatic example: Breakdown of the multishellcytokine network fuels cancer in aged people. Bioessays 2011; 34:40-49
-
(2011)
Bioessays
, vol.34
, pp. 40-49
-
-
Bonafè, M.1
Storci, G.2
Franceschi, C.3
-
28
-
-
5444246811
-
Metabolic syndrome X: An inflammatory condition?
-
Das UN. Metabolic syndrome X: an inflammatory condition? Curr HypertensRep 2004; 6:66-73 (Pubitemid 39359545)
-
(2004)
Current Hypertension Reports
, vol.6
, Issue.1
, pp. 66-73
-
-
Das, U.N.1
-
30
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. NatRev Immunol 2011; 11:98-107
-
(2011)
NatRev Immunol
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
32
-
-
77950199929
-
Age-related inflammation: Thecontribution of different organs, tissues and systems. How to face it fortherapeutic approaches
-
Cevenini E, Caruso C, Candore G, et al. Age-related inflammation: thecontribution of different organs, tissues and systems. How to face it fortherapeutic approaches. Curr Pharm Des 2010; 16:609-618
-
(2010)
Curr Pharm des
, vol.16
, pp. 609-618
-
-
Cevenini, E.1
Caruso, C.2
Candore, G.3
-
33
-
-
83555173345
-
Gut microbiota as a candidate forlifespan extension: An ecological/evolutionary perspective targeted on livingorganisms as metaorganisms
-
Ottaviani E, Ventura N, Mandrioli M, et al. Gut microbiota as a candidate forlifespan extension: an ecological/evolutionary perspective targeted on livingorganisms as metaorganisms. Biogerontology 2011; 12:599-609
-
(2011)
Biogerontology
, vol.12
, pp. 599-609
-
-
Ottaviani, E.1
Ventura, N.2
Mandrioli, M.3
-
34
-
-
84864722033
-
Gut microbiota composition correlateswith diet and health in the elderly
-
Claesson MJ, Jeffery IB, Conde S, et al. Gut microbiota composition correlateswith diet and health in the elderly. Nature 2012; 488:178-184
-
(2012)
Nature
, vol.488
, pp. 178-184
-
-
Claesson, M.J.1
Jeffery, I.B.2
Conde, S.3
-
35
-
-
7944231342
-
Does the microbiota regulate immune responses outside the gut?
-
DOI 10.1016/j.tim.2004.10.008, PII S0966842X04002409
-
Noverr MC, Huffnagle GB. Does the microbiota regulate immune responsesoutside the gut? Trends Microbiol 2004; 12:562-568 (Pubitemid 39469905)
-
(2004)
Trends in Microbiology
, vol.12
, Issue.12
, pp. 562-568
-
-
Noverr, M.C.1
Huffnagle, G.B.2
-
36
-
-
77955602581
-
Through aging and beyond: Gutmicrobiota and inflammatory status in seniors and centenarians
-
Erratum in: PLoS One. 2010 5(6) doi: 10.1371/annotation/df45912f-d15c- 44ab-8312-e7ec0607604d
-
Biagi E, Nylund L, Candela M, et al. Through aging, and beyond: gutmicrobiota and inflammatory status in seniors and centenarians. PLoS One2010; 5:e10667. Erratum in: PLoS One. 2010;5(6). doi: 10.1371/annotation/df45912f- d15c-44ab-8312-e7ec0607604d
-
(2010)
PLoS One
, vol.5
-
-
Biagi, E.1
Nylund, L.2
Candela, M.3
-
37
-
-
84862149788
-
Aging of the human metaorganism:The microbial counterpart
-
Biagi E, Candela M, Fairweather-Tait S, et al. Aging of the human metaorganism:the microbial counterpart. Age 2012; 34:247-267
-
(2012)
Age
, vol.34
, pp. 247-267
-
-
Biagi, E.1
Candela, M.2
Fairweather-Tait, S.3
-
38
-
-
59849113547
-
Microbes in gastrointestinal health and disease
-
Neish AS. Microbes in gastrointestinal health and disease. Gastroenterology2009; 136:65-80
-
(2009)
Gastroenterology
, vol.136
, pp. 65-80
-
-
Neish, A.S.1
-
39
-
-
78651401198
-
Human intestinal microbiota: Crosstalkwith the host and its potential role in colorectal cancer
-
Candela M, Guidotti M, Fabbri A, et al. Human intestinal microbiota: crosstalkwith the host and its potential role in colorectal cancer. Crit Rev Microbiol2011; 37:1-14
-
(2011)
Crit Rev Microbiol
, vol.37
, pp. 1-14
-
-
Candela, M.1
Guidotti, M.2
Fabbri, A.3
-
40
-
-
0029935217
-
Age related changes in gut physiology and nutritional status
-
Lovat LB. Age related changes in gut physiology and nutritional status. Gut1996; 38:306-309 (Pubitemid 26074310)
-
(1996)
Gut
, vol.38
, Issue.3
, pp. 306-309
-
-
Lovat, L.B.1
-
41
-
-
39649085837
-
Inflamm-aging as a major characteristic of old people: Can it beprevented or cured?
-
Franceschi C. Inflamm-aging as a major characteristic of old people: can it beprevented or cured? Nutr Rev 2007; 65:S173-176
-
(2007)
Nutr Rev
, vol.65
-
-
Franceschi, C.1
-
42
-
-
84866738529
-
Transfer of intestinal microbiota fromlean donors increases insulin sensitivity in individuals with metabolic syndrome
-
Vrieze A, van Nood E, Holleman F, et al. Transfer of intestinal microbiota fromlean donors increases insulin sensitivity in individuals with metabolic syndrome.Gastroenterology 2012; 143:913-916
-
(2012)
Gastroenterology
, vol.143
, pp. 913-916
-
-
Vrieze, A.1
Van Nood, E.2
Holleman, F.3
-
43
-
-
84855357614
-
The therapeutic potential of manipulatinggut microbiota in obesity and type 2 diabetes mellitus
-
Kootte RS, Vrieze A, Holleman F, et al. The therapeutic potential of manipulatinggut microbiota in obesity and type 2 diabetes mellitus. Diabetes ObesMetab 2012; 14:112-120
-
(2012)
Diabetes ObesMetab
, vol.14
, pp. 112-120
-
-
Kootte, R.S.1
Vrieze, A.2
Holleman, F.3
|