-
1
-
-
0035851187
-
Ppar: A nuclear regulator of metabolism, differentiation, and cell growth
-
E. D. Rosen and B. M. Spiegelman, "PPAR: a nuclear regulator of metabolism, differentiation, and cell growth," The Journal of Biological Chemistry, vol. 276, no. 41, pp. 37731-37734, 2001.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.41
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
2
-
-
11144310564
-
An overview on biologicalmechanisms of ppars
-
B. P. Kota, T. H. Huang, and B. D. Roufogalis, "An overview on biologicalmechanisms of PPARs," Pharmacological Research, vol. 51, no. 2, pp. 85-94, 2005.
-
(2005)
Pharmacological Research
, vol.51
, Issue.2
, pp. 85-94
-
-
Kota, B.P.1
Huang, T.H.2
Roufogalis, B.D.3
-
3
-
-
84877329207
-
Ppar signaling and metabolism: The good, the bad and the future
-
M. Ahmadian, J. M. Suh, N. Hah et al., "PPAR signaling and metabolism: the good, the bad and the future," Nature Medicine, vol. 19, no. 5, pp. 557-566, 2013.
-
(2013)
Nature Medicine
, vol.19
, Issue.5
, pp. 557-566
-
-
Ahmadian, M.1
Suh, J.M.2
Hah, N.3
-
4
-
-
0030462770
-
The peroxisome proliferator-Activated receptors: Ligands and activators
-
B. M. Forman, J. Chen, and R. M. Evans, "The peroxisome proliferator-Activated receptors: ligands and activators," Annals of theNew YorkAcademy of Sciences, vol. 804, pp. 266-275, 1996.
-
(1996)
Annals of TheNew YorkAcademy of Sciences
, vol.804
, pp. 266-275
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
5
-
-
77449141973
-
Peroxisome proliferator-Activated receptor (ppar) /: A new potential therapeutic target for the treatment of metabolic syndrome
-
T. Coll, R. Rodríguez-Calvo, E. Barroso et al., "Peroxisome proliferator-Activated receptor (PPAR) /: a new potential therapeutic target for the treatment of metabolic syndrome," Current Molecular Pharmacology, vol. 2, no. 1, pp. 46-55, 2009.
-
(2009)
Current Molecular Pharmacology
, vol.2
, Issue.1
, pp. 46-55
-
-
Coll, T.1
Rodríguez-Calvo, R.2
Barroso, E.3
-
6
-
-
0033213637
-
Ppar is required for placental, cardiac, and adipose tissue development
-
Y. Barak, M. C. Nelson, E. S.Ong et al., "PPAR is required for placental, cardiac, and adipose tissue development," Molecular Cell, vol. 4, no. 4, pp. 585-595, 1999.
-
(1999)
Molecular Cell
, vol.4
, Issue.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
-
8
-
-
79955692835
-
A role for central nervous system ppar- in the regulation of energy balance
-
K. K. Ryan, B. Li, B. E. Grayson, E. K. Matter, S. C.Woods, and R. J. Seeley, "A role for central nervous system PPAR- in the regulation of energy balance," Nature Medicine, vol. 17, no. 5, pp. 623-626, 2011.
-
(2011)
Nature Medicine
, vol.17
, Issue.5
, pp. 623-626
-
-
Ryan, K.K.1
Li, B.2
Grayson, B.E.3
Matter, E.K.4
Woods, S.C.5
Seeley, R.J.6
-
9
-
-
19244365650
-
Thiazolidinediones
-
H. Yki-Järvinen, "Thiazolidinediones," New England Journal of Medicine, vol. 351, no. 11, pp. 1106-1158, 2004.
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.11
, pp. 1106-1158
-
-
Yki-Järvinen, H.1
-
10
-
-
0036260784
-
Peroxisome proliferator-Activated receptor- agonists prevent experimental autoimmune encephalomyelitis
-
D. L. Feinstein, E. Galea, V. Gavrilyuk et al., "Peroxisome proliferator-Activated receptor- agonists prevent experimental autoimmune encephalomyelitis," Annals of Neurology, vol. 51, no. 6, pp. 694-702, 2002.
-
(2002)
Annals of Neurology
, vol.51
, Issue.6
, pp. 694-702
-
-
Feinstein, D.L.1
Galea, E.2
Gavrilyuk, V.3
-
11
-
-
67349225826
-
Delayed post ischemic treatment with rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat
-
M. Allahtavakoli, R. Moloudi, M. K. Arababadi, A. Shamsizadeh, and K. Javanmardi, "Delayed post ischemic treatment with Rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat," Brain Research, vol. 1271, pp. 121-127, 2009.
-
(2009)
Brain Research
, vol.1271
, pp. 121-127
-
-
Allahtavakoli, M.1
Moloudi, R.2
Arababadi, M.K.3
Shamsizadeh, A.4
Javanmardi, K.5
-
12
-
-
43949138943
-
Potential therapeutic targets for ppar after spinal cord injury
-
Article ID 517162
-
D. M. McTigue, "Potential therapeutic targets for PPAR after spinal cord injury," PPAR Research, vol. 2008,Article ID 517162, 7 pages, 2008.
-
(2008)
PPAR Research
, vol.2008
-
-
McTigue, D.M.1
-
13
-
-
84869090003
-
Candesartan, an angiotensin ii at 1-receptor blocker and ppar- agonist, reduces lesion volume and improvesmotor andmemory function after traumatic brain injury in mice
-
S. Villapol, A. K. Yaszemski, T. T. Logan, E. Sánchez-Lemus, J. M. Saavedra, and A. J. Symes, "Candesartan, an angiotensin II at 1-receptor blocker and PPAR- agonist, reduces lesion volume and improvesmotor andmemory function after traumatic brain injury in mice," Neuropsychopharmacology, vol. 37, no. 13, pp. 2817-2829, 2012.
-
(2012)
Neuropsychopharmacology
, vol.37
, Issue.13
, pp. 2817-2829
-
-
Villapol, S.1
Yaszemski, A.K.2
Logan, T.T.3
Sánchez-Lemus, E.4
Saavedra, J.M.5
Symes, A.J.6
-
14
-
-
33847093475
-
Thiazolidinedione class of peroxisome proliferator-Activated receptor agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
-
S. Park, J. Yi, G. Miranpuri et al., "Thiazolidinedione class of peroxisome proliferator-Activated receptor agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats," The Journal of Pharmacology and Experimental Therapeutics, vol. 320, no. 3, pp. 1002-1012, 2007.
-
(2007)
The Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.3
, pp. 1002-1012
-
-
Park, S.1
Yi, J.2
Miranpuri, G.3
-
15
-
-
11844269951
-
Peroxisome proliferator-Activated receptor-gamma agonist extends survival in transgenicmousemodel of amyotrophic lateral sclerosis
-
M. Kiaei, K. Kipiani, J. Chen, N. Y. Calingasan, and M. F. Beal, "Peroxisome proliferator-Activated receptor-gamma agonist extends survival in transgenicmousemodel of amyotrophic lateral sclerosis," ExperimentalNeurology, vol. 191, no. 2,pp. 331-336, 2005.
-
(2005)
ExperimentalNeurology
, vol.191
, Issue.2
, pp. 331-336
-
-
Kiaei, M.1
Kipiani, K.2
Chen, J.3
Calingasan, N.Y.4
Beal, M.F.5
-
16
-
-
44849091020
-
Effects of the ppar activator pioglitazone on p38 map kinase and ib in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis
-
N. Shibata, M. Kawaguchi-Niida, T. Yamamoto, S. Toi, A. Hirano, and M. Kobayashi, "Effects of the PPAR activator pioglitazone on p38 MAP kinase and IB in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis," Neuropathology, vol. 28, no. 4, pp. 387-398, 2008.
-
(2008)
Neuropathology
, vol.28
, Issue.4
, pp. 387-398
-
-
Shibata, N.1
Kawaguchi-Niida, M.2
Yamamoto, T.3
Toi, S.4
Hirano, A.5
Kobayashi, M.6
-
17
-
-
84867749744
-
The peroxisome proliferator-Activated receptor (ppar) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis
-
V. Benedusi, F.Martorana, L. Brambilla, A.Maggi, andD. Rossi, "The peroxisome proliferator-Activated receptor (PPAR) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis," Journal of Biological Chemistry, vol. 287, no. 43, pp. 35899-35911, 2012.
-
(2012)
Journal of Biological Chemistry
, vol.287
, Issue.43
, pp. 35899-35911
-
-
Benedusi, V.1
Martorana, F.2
Brambilla, L.3
Maggi, A.4
Rossi, D.5
-
18
-
-
20444499367
-
Acute treatment with the ppar agonist pioglitazone and ibuprofen reduces glial inflammation and a1-42 levels in appv717i transgenic mice
-
M. T. Heneka, M. Sastre, L. Dumitrescu-Ozimek et al., "Acute treatment with the PPAR agonist pioglitazone and ibuprofen reduces glial inflammation and A1-42 levels in APPV717I transgenic mice," Brain, vol. 128, no. 6, pp. 1442-1453, 2005.
-
(2005)
Brain
, vol.128
, Issue.6
, pp. 1442-1453
-
-
Heneka, M.T.1
Sastre, M.2
Dumitrescu-Ozimek, L.3
-
19
-
-
55249125525
-
Complete rescue of cerebrovascular function in aged alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-Activated receptor agonist
-
N. Nicolakakis, T. Aboulkassim, B. Ongali et al., "Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-Activated receptor agonist," The Journal of Neuroscience, vol. 28, no. 37, pp. 9287-9296, 2008.
-
(2008)
The Journal of Neuroscience
, vol.28
, Issue.37
, pp. 9287-9296
-
-
Nicolakakis, N.1
Aboulkassim, T.2
Ongali, B.3
-
20
-
-
77249109792
-
Activation of wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an appswe/psen1?e9 mouse model of alzheimer's disease
-
E. M. Toledo and N. C. Inestrosa, "Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1?E9 mouse model of Alzheimer's disease," Molecular Psychiatry, vol. 15, no. 3, pp. 272-285, 2010.
-
(2010)
Molecular Psychiatry
, vol.15
, Issue.3
, pp. 272-285
-
-
Toledo, E.M.1
Inestrosa, N.C.2
-
21
-
-
84870023505
-
Cognitive enhancement with rosiglitazone links the hippocampal ppar and erk mapk signaling pathways
-
L. A. Denner, J. Rodriguez-Rivera, S. J. Haidacher et al., "Cognitive enhancement with rosiglitazone links the hippocampal PPAR and ERK MAPK signaling pathways," The Journal of Neuroscience, vol. 32, no. 47, pp. 16725-16735, 2012.
-
(2012)
The Journal of Neuroscience
, vol.32
, Issue.47
, pp. 16725-16735
-
-
Denner, L.A.1
Rodriguez-Rivera, J.2
Haidacher, S.J.3
-
22
-
-
84864249514
-
Mechanisms underlying the rapid peroxisome proliferator-Activated receptor-mediated amyloid clearance and reversal of cognitive deficits in a murine model of alzheimer's disease
-
S.Mandrekar-Colucci, J. C. Karlo, and G. E. Landreth, "Mechanisms underlying the rapid peroxisome proliferator-Activated receptor-mediated Amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease," The Journal of Neuroscience, vol. 32, no. 30, pp. 10117-10128, 2012.
-
(2012)
The Journal of Neuroscience
, vol.32
, Issue.30
, pp. 10117-10128
-
-
Mandrekar-Colucci, S.1
Karlo, J.C.2
Landreth, G.E.3
-
23
-
-
84892417325
-
Cognitive enhancing treatment with a ppar agonist normalizes dentate granule cell presynaptic function in tg2576 app mice
-
M. N. Nenov, F. Laezza, S. J. Haidacher et al., "Cognitive enhancing treatment with a PPAR agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice," Journal of Neuroscience, vol. 34, no. 3, pp. 1028-1036, 2014.
-
(2014)
Journal of Neuroscience
, vol.34
, Issue.3
, pp. 1028-1036
-
-
Nenov, M.N.1
Laezza, F.2
Haidacher, S.J.3
-
24
-
-
84870226700
-
Ppar/rxra-induced and cd36-mediated microglial amyloid- phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice
-
M. Yamanaka, T. Ishikawa, A. Griep, D. Axt, M. P. Kummer, and M. T. Heneka, "PPAR/RXRA-induced and CD36-mediated microglial amyloid- phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice," Journal of Neuroscience, vol. 32, no. 48, pp. 17321-17331, 2012.
-
(2012)
Journal of Neuroscience
, vol.32
, Issue.48
, pp. 17321-17331
-
-
Yamanaka, M.1
Ishikawa, T.2
Griep, A.3
Axt, D.4
Kummer, M.P.5
Heneka, M.T.6
-
25
-
-
73949155834
-
Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration
-
S. Takahashi, T. Ohshima, M. Hirasawa et al., "Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration," The American Journal of Pathology, vol. 176, no. 1, pp. 320-329, 2010.
-
(2010)
The American Journal of Pathology
, vol.176
, Issue.1
, pp. 320-329
-
-
Takahashi, S.1
Ohshima, T.2
Hirasawa, M.3
-
26
-
-
84893204721
-
Suppression of neuroinflammation in forebrain-specific cdk5 conditional knockout mice by ppar agonist improves neuronal loss and early lethality
-
article 28
-
E. Utreras, R. Hamada, M. Prochazkova et al., "Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPAR agonist improves neuronal loss and early lethality," Journal of Neuroinflammation, vol. 11, article 28, 2014.
-
(2014)
Journal of Neuroinflammation
, vol.11
-
-
Utreras, E.1
Hamada, R.2
Prochazkova, M.3
-
27
-
-
84901049784
-
Pgc-1 overexpression exacerbates -Amyloid and tau deposition in a transgenic mouse model of alzheimer's disease
-
M.Dumont, C. Stack, C. Elipenahli et al., "PGC-1 overexpression exacerbates -Amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease," The FASEB Journal, vol. 28, no. 4, pp. 1745-1755, 2014.
-
(2014)
The FASEB Journal
, vol.28
, Issue.4
, pp. 1745-1755
-
-
Dumont, M.1
Stack, C.2
Elipenahli, C.3
-
28
-
-
84860695796
-
Pgc-1 at the intersection of bioenergetics regulation and neuron function: From huntington's disease to parkinson's disease and beyond
-
T. Tsunemi and A. R. La Spada, "PGC-1 at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond," Progress in Neurobiology, vol. 97, no. 2, pp. 142-151, 2012.
-
(2012)
Progress in Neurobiology
, vol.97
, Issue.2
, pp. 142-151
-
-
Tsunemi, T.1
La Spada, A.R.2
-
29
-
-
84890872906
-
Ppar agonists as therapeutics for cns trauma and neurological diseases
-
S.Mandrekar-Colucci, A. Sauerbeck, P. G. Popovich, andD. M. McTigue, "PPAR agonists as therapeutics for CNS trauma and neurological diseases," ASN Neuro, vol. 5, no. 5, 2013.
-
(2013)
ASN Neuro
, vol.5
, Issue.5
-
-
Mandrekar-Colucci, S.1
Sauerbeck, A.2
Popovich, P.G.3
McTigue, D.M.4
-
30
-
-
33748909537
-
Altered ppar expression and activation after transient focal ischemia in rats
-
N. A. Victor, E. W. Wanderi, J. Gamboa et al., "Altered PPAR expression and activation after transient focal ischemia in rats," European Journal of Neuroscience, vol. 24, no. 6, pp. 1653-1663, 2006.
-
(2006)
European Journal of Neuroscience
, vol.24
, Issue.6
, pp. 1653-1663
-
-
Victor, N.A.1
Wanderi, E.W.2
Gamboa, J.3
-
31
-
-
10044289268
-
Peroxisome proliferator-Activated receptor- ligands reduce inflammation and infarction size in transient focal ischemia
-
S. Sundararajan, J. L. Gamboa, N. A. Victor, E. W. Wanderi, W. D. Lust, and G. E. Landreth, "Peroxisome proliferator-Activated receptor- ligands reduce inflammation and infarction size in transient focal ischemia," Neuroscience, vol. 130, no. 3, pp. 685-696, 2005.
-
(2005)
Neuroscience
, vol.130
, Issue.3
, pp. 685-696
-
-
Sundararajan, S.1
Gamboa, J.L.2
Victor, N.A.3
Wanderi, E.W.4
Lust, W.D.5
Landreth, G.E.6
-
32
-
-
66049135616
-
Neuronal ppar deficiency increases susceptibility to brain damage after cerebral ischemia
-
X. Zhao, R. Strong, J. Zhang et al., "Neuronal PPAR deficiency increases susceptibility to brain damage after cerebral ischemia," The Journal of Neuroscience, vol. 29, no. 19, pp. 6186-6195, 2009.
-
(2009)
The Journal of Neuroscience
, vol.29
, Issue.19
, pp. 6186-6195
-
-
Zhao, X.1
Strong, R.2
Zhang, J.3
-
33
-
-
80053261316
-
Rosiglitazone enhances the proliferation of neural progenitor cells and inhibits inflammation response after spinal cord injury
-
Q. Meng, X. Liang, P. Wang et al., "Rosiglitazone enhances the proliferation of neural progenitor cells and inhibits inflammation response after spinal cord injury," Neuroscience Letters, vol. 503, no. 3, pp. 191-195, 2011.
-
(2011)
Neuroscience Letters
, vol.503
, Issue.3
, pp. 191-195
-
-
Meng, Q.1
Liang, X.2
Wang, P.3
-
34
-
-
84872845566
-
Peroxisome proliferator-Activated receptor- agonist 15d-prostaglandin j2 mediates neuronal autophagy after cerebral ischemiareperfusion injury
-
Article ID e55080
-
F. Xu, J. Li, W. Ni, Y. Shen, and X. Zhang, "Peroxisome proliferator-Activated receptor- agonist 15d-prostaglandin J2 mediates neuronal autophagy after cerebral ischemiareperfusion injury," PLoS ONE, vol. 8, no. 1, Article ID e55080, 2013.
-
(2013)
PLoS ONE
, vol.8
, Issue.1
-
-
Xu, F.1
Li, J.2
Ni, W.3
Shen, Y.4
Zhang, X.5
-
35
-
-
37549060702
-
Peroxisome proliferator-Activated receptor up-regulates the bcl-2 antiapoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis
-
K. Fuenzalida, R. Quintanilla, P. Ramos et al., "Peroxisome proliferator-Activated receptor up-regulates the Bcl-2 antiapoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis," The Journal of Biological Chemistry, vol. 282, no. 51, pp. 37006-37015, 2007.
-
(2007)
The Journal of Biological Chemistry
, vol.282
, Issue.51
, pp. 37006-37015
-
-
Fuenzalida, K.1
Quintanilla, R.2
Ramos, P.3
-
36
-
-
13644271368
-
Peroxisome proliferator-Activated receptor is expressed in hippocampal neurons and its activation prevents -Amyloid neurodegeneration: Ole ofwnt signaling
-
N. C. Inestrosa, J. A. Godoy, R. A. Quintanilla, C. S. Koenig, and M. Bronfman, "Peroxisome proliferator-Activated receptor is expressed in hippocampal neurons and its activation prevents -Amyloid neurodegeneration: ole ofWnt signaling," Experimental Cell Research, vol. 304, no. 1, pp. 91-104, 2005.
-
(2005)
Experimental Cell Research
, vol.304
, Issue.1
, pp. 91-104
-
-
Inestrosa, N.C.1
Godoy, J.A.2
Quintanilla, R.A.3
Koenig, C.S.4
Bronfman, M.5
-
37
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
R. S. Jope and G. V. W. Johnson, "The glamour and gloom of glycogen synthase kinase-3," Trends in Biochemical Sciences, vol. 29, no. 2, pp. 95-102, 2004.
-
(2004)
Trends in Biochemical Sciences
, vol.29
, Issue.2
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.W.2
-
38
-
-
84875841285
-
Wnt signaling: Role in alzheimer disease and schizophrenia
-
N. C. Inestrosa, C.Montecinos-Oliva, and M. Fuenzalida, "Wnt signaling: role in Alzheimer disease and schizophrenia," Journal of Neuroimmune Pharmacology, vol. 7, no. 4, pp. 788-807, 2012.
-
(2012)
Journal of Neuroimmune Pharmacology
, vol.7
, Issue.4
, pp. 788-807
-
-
Inestrosa, N.C.1
Montecinos-Oliva, C.2
Fuenzalida, M.3
-
39
-
-
28844467909
-
Peroxisomal proliferation protects from -Amyloid neurodegeneration
-
M. J. Santos, R. A. Quintanilla, A. Toro et al., "Peroxisomal proliferation protects from -Amyloid neurodegeneration," Journal of Biological Chemistry, vol. 280, no. 49, pp. 41057-41068, 2005.
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 41057-41068
-
-
Santos, M.J.1
Quintanilla, R.A.2
Toro, A.3
-
40
-
-
29244476043
-
Rosiglitazone protects human neuroblastoma sh-sy5y cells against acetaldehydeinduced cytotoxicity
-
T.W. Jung, J. Y. Lee, W. S. Shim et al., "Rosiglitazone protects human neuroblastoma SH-SY5Y cells against acetaldehydeinduced cytotoxicity," Biochemical and Biophysical Research Communications, vol. 340, no. 1, pp. 221-227, 2006.
-
(2006)
Biochemical and Biophysical Research Communications
, vol.340
, Issue.1
, pp. 221-227
-
-
Jung, T.W.1
Lee, J.Y.2
Shim, W.S.3
-
41
-
-
8644246576
-
A prospective study of alcoholism and the risk of parkinson's disease
-
M. A. Hernán, G. Logroscino, and L. A. Garciá Rodríguez, "A prospective study of alcoholism and the risk of Parkinson's disease," Journal of Neurology, vol. 251, no. 7, pp. VII14-VII17, 2004.
-
(2004)
Journal of Neurology
, vol.251
, Issue.7
, pp. VII14-VII17
-
-
Hernán, M.A.1
Logroscino, G.2
Garciá Rodríguez, L.A.3
-
42
-
-
33846610917
-
Rosiglitazone protects human neuroblastoma sh-sy5y cells against mpp+ induced cytotoxicity via inhibition of mitochondrial dysfunction and ros production
-
T.W. Jung, J. Y. Lee, W. S. Shim et al., "Rosiglitazone protects human neuroblastoma SH-SY5Y cells against MPP+ induced cytotoxicity via inhibition of mitochondrial dysfunction and ROS production," Journal of the Neurological Sciences, vol. 253, no. 1-2, pp. 53-60, 2007.
-
(2007)
Journal of the Neurological Sciences
, vol.253
, Issue.1-2
, pp. 53-60
-
-
Jung, T.W.1
Lee, J.Y.2
Shim, W.S.3
-
43
-
-
54449092109
-
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: Possible role of peroxisome proliferator-Activated receptor- (ppar) in the pathogenesis of huntington disease
-
R. A. Quintanilla, Y. N. Jin, K. Fuenzalida, M. Bronfman, and G. V. W. Johnson, "Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-Activated receptor- (PPAR) in the pathogenesis of huntington disease,"TheJournal of Biological Chemistry, vol. 283, no. 37, pp. 25628-25637, 2008.
-
(2008)
TheJournal of Biological Chemistry
, vol.283
, Issue.37
, pp. 25628-25637
-
-
Quintanilla, R.A.1
Jin, Y.N.2
Fuenzalida, K.3
Bronfman, M.4
Johnson, G.V.W.5
-
44
-
-
70349422148
-
Role of mitochondrial dysfunction in the pathogenesis of huntington's disease
-
R. A. Quintanilla and G. V.W. Johnson, "Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease," Brain Research Bulletin, vol. 80, no. 4-5, pp. 242-247, 2009.
-
(2009)
Brain Research Bulletin
, vol.80
, Issue.4-5
, pp. 242-247
-
-
Quintanilla, R.A.1
Johnson, G.V.W.2
-
45
-
-
80055022344
-
The ppar alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice
-
A. Almad, A. T. Lash, P. Wei, A. E. Lovett-Racke, and D. M. McTigue, "The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice," Experimental Neurology, vol. 232, no. 2, pp. 309-317, 2011.
-
(2011)
Experimental Neurology
, vol.232
, Issue.2
, pp. 309-317
-
-
Almad, A.1
Lash, A.T.2
Wei, P.3
Lovett-Racke, A.E.4
McTigue, D.M.5
-
46
-
-
0035888154
-
Activation of the peroxisome proliferator-Activated receptor- enhances cell death in cultured cerebellar granule cells
-
S. A. Smith, F. J. May, G. R. Monteith, and S. J. Roberts-Thomson, "Activation of the peroxisome proliferator-Activated receptor- enhances cell death in cultured cerebellar granule cells," Journal of Neuroscience Research, vol. 66, no. 2, pp. 236-241, 2001.
-
(2001)
Journal of Neuroscience Research
, vol.66
, Issue.2
, pp. 236-241
-
-
Smith, S.A.1
May, F.J.2
Monteith, G.R.3
Roberts-Thomson, S.J.4
-
47
-
-
77956090575
-
Rosiglitazone monotherapy in mild-to-moderate alzheimer's disease: Results from a randomized, double-blind, placebo-controlled phase iii study
-
M. Gold, C. Alderton, M. Zvartau-Hind et al., "Rosiglitazone monotherapy in mild-to-moderate alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III study," Dementia and Geriatric Cognitive Disorders, vol. 30, no. 2, pp. 131-146, 2010.
-
(2010)
Dementia and Geriatric Cognitive Disorders
, vol.30
, Issue.2
, pp. 131-146
-
-
Gold, M.1
Alderton, C.2
Zvartau-Hind, M.3
-
48
-
-
33745266146
-
Efficacy of rosiglitazone in a genetically defined population with mild-tomoderate alzheimer's disease
-
M. E. Risner, A. M. Saunders, J. F. B. Altman et al., "Efficacy of rosiglitazone in a genetically defined population with mild-tomoderate Alzheimer's disease," The Pharmacogenomics Journal, vol. 6, no. 4, pp. 246-254, 2006.
-
(2006)
The Pharmacogenomics Journal
, vol.6
, Issue.4
, pp. 246-254
-
-
Risner, M.E.1
Saunders, A.M.2
Altman, J.F.B.3
-
49
-
-
84862010340
-
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis
-
Article ID e37885
-
L. Dupuis, R. Dengler, M. T. Heneka et al., "A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis," PLoS ONE, vol. 7, no. 6,Article ID e37885, 2012.
-
(2012)
PLoS ONE
, vol.7
, Issue.6
-
-
Dupuis, L.1
Dengler, R.2
Heneka, M.T.3
-
50
-
-
0035142007
-
Survival activity of troglitazone in rat motoneurones
-
C. Nishijima, K. Kimoto, and Y. Arakawa, "Survival activity of troglitazone in rat motoneurones," Journal of Neurochemistry, vol. 76, no. 2, pp. 383-390, 2001.
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.2
, pp. 383-390
-
-
Nishijima, C.1
Kimoto, K.2
Arakawa, Y.3
-
51
-
-
0035952497
-
15-Deoxy-?12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-Activated receptor-, induces neuronal apoptosis
-
nT. T. Rohn, S. M. Wong, C. W. Cotman, and D. H. Cribbs, "15-Deoxy-?12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-Activated receptor-, induces neuronal apoptosis," NeuroReport, vol. 12, no. 4, pp. 839-843, 2001.
-
(2001)
NeuroReport
, vol.12
, Issue.4
, pp. 839-843
-
-
Rohn, T.T.1
Wong, S.M.2
Cotman, C.W.3
Cribbs, D.H.4
-
52
-
-
0038320030
-
Effects of peroxisome proliferator-Activated receptor ligands ciglitazone and 15-deoxy-12,14-prostaglandin j2 on rat cultured cerebellar granule neuronal viability
-
S. A. Smith, G. R. Monteith, N. A. Holman, J. A. Robinson, F. J. May, and S. J. Roberts-Thomson, "Effects of peroxisome proliferator-Activated receptor ligands ciglitazone and 15-deoxy-12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability," Journal of Neuroscience Research, vol. 72, no. 6, pp. 747-755, 2003.
-
(2003)
Journal of Neuroscience Research
, vol.72
, Issue.6
, pp. 747-755
-
-
Smith, S.A.1
Monteith, G.R.2
Holman, N.A.3
Robinson, J.A.4
May, F.J.5
Roberts-Thomson, S.J.6
-
53
-
-
79955118177
-
Could thiazolidinediones increase the risk of heart failure in friedreich's ataxia patients?
-
J. L. Garciá-Giménez, F. Sanchis-Gomar, and F. V. Pallardó, "Could thiazolidinediones increase the risk of heart failure in Friedreich's ataxia patients?" Movement Disorders, vol. 26, no. 5, pp. 769-771, 2011.
-
(2011)
Movement Disorders
, vol.26
, Issue.5
, pp. 769-771
-
-
Garciá-Giménez, J.L.1
Sanchis-Gomar, F.2
Pallardó, F.V.3
-
54
-
-
78651322583
-
A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with alzheimer disease
-
D.S.Geldmacher, T. Fritsch,M. J.McClendon, andG.Landreth, "A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with alzheimer disease," Archives of Neurology, vol. 68, no. 1, pp. 45-50, 2011.
-
(2011)
Archives of Neurology
, vol.68
, Issue.1
, pp. 45-50
-
-
Geldmacher, D.S.1
Fritsch, T.2
McClendon, M.J.3
Landreth, G.4
-
55
-
-
33744962510
-
Peroxisome proliferator-Activated receptor -mediated regulation of neural stem cell proliferation and differentiation
-
K. Wada, A. Nakajima, K. Katayama et al., "Peroxisome proliferator-Activated receptor -mediated regulation of neural stem cell proliferation and differentiation," The Journal of Biological Chemistry, vol. 281, no. 18, pp. 12673-12681, 2006.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, Issue.18
, pp. 12673-12681
-
-
Wada, K.1
Nakajima, A.2
Katayama, K.3
-
56
-
-
0030297962
-
Molecular cloning of a human neurod from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum
-
M. Yokoyama, Y. Nishi, Y. Miyamoto et al., "Molecular cloning of a human neuroD from a neuroblastoma cell line specifically expressed in the fetal brain and adult cerebellum," Molecular Brain Research, vol. 42, no. 1, pp. 135-139, 1996.
-
(1996)
Molecular Brain Research
, vol.42
, Issue.1
, pp. 135-139
-
-
Yokoyama, M.1
Nishi, Y.2
Miyamoto, Y.3
-
57
-
-
82655189157
-
Cannabidiol reduces a-induced neuroinflammation and promotes hippocampal neurogenesis through ppar involvement
-
Article ID e28668
-
G. Esposito, C. Scuderi,M. Valenza et al., "Cannabidiol reduces A-induced neuroinflammation and promotes hippocampal neurogenesis through PPAR involvement," PLoS ONE, vol. 6, no. 12, Article ID e28668, 2011.
-
(2011)
PLoS ONE
, vol.6
, Issue.12
-
-
Esposito, G.1
Scuderi, C.2
Valenza, M.3
-
58
-
-
62949132160
-
Ppar stimulation promotes neurite outgrowth in sh-sy5y human neuroblastoma cells
-
G. Miglio, L. Rattazzi, A. C. Rosa, and R. Fantozzi, "PPAR stimulation promotes neurite outgrowth in SH-SY5Y human neuroblastoma cells," Neuroscience Letters, vol. 454, no. 2, pp. 134-138, 2009.
-
(2009)
Neuroscience Letters
, vol.454
, Issue.2
, pp. 134-138
-
-
Miglio, G.1
Rattazzi, L.2
Rosa, A.C.3
Fantozzi, R.4
-
59
-
-
80053541949
-
The influence of peroxisome proliferator-Activated receptor 1 during differentiation of mouse embryonic stem cells to neural cells
-
A. Ghoochani, K. Shabani, M. Peymani et al., "The influence of peroxisome proliferator-Activated receptor 1 during differentiation of mouse embryonic stem cells to neural cells," Differentiation, vol. 83, no. 1, pp. 60-67, 2012.
-
(2012)
Differentiation
, vol.83
, Issue.1
, pp. 60-67
-
-
Ghoochani, A.1
Shabani, K.2
Peymani, M.3
-
60
-
-
0345701304
-
Activation of p38 mitogen-Activated protein kinase and activator protein-1 during the promotion of neurite extension of pc-12 cells by 15-deoxy-?12,14-prostaglandin j2
-
K. M. Jung, K. S. Park, J. H. Oh et al., "Activation of p38 mitogen-Activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-?12,14-prostaglandin J2," Molecular Pharmacology, vol. 63, no. 3, pp. 607-616, 2003.
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.3
, pp. 607-616
-
-
Jung, K.M.1
Park, K.S.2
Oh, J.H.3
-
61
-
-
84878607763
-
Thiazolidinediones promote axonal growth through the activation of the jnk pathway
-
Article ID e65140
-
R. A. Quintanilla, J. A. Godoy, I. Alfaro et al., "Thiazolidinediones promote axonal growth through the activation of the JNK pathway," PLoS ONE, vol. 8, no. 5,Article ID e65140, 2013.
-
(2013)
PLoS ONE
, vol.8
, Issue.5
-
-
Quintanilla, R.A.1
Godoy, J.A.2
Alfaro, I.3
-
62
-
-
84871259864
-
Retinoic acid induces neurogenesis by activating both retinoic acid receptors (rars) and peroxisome proliferator-Activated receptor / (ppar/)
-
S. Yu, L. Levi, R. Siegel, and N. Noy, "Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-Activated receptor / (PPAR/)," The Journal of Biological Chemistry, vol. 287, no. 50, pp. 42195-42205, 2012.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, Issue.50
, pp. 42195-42205
-
-
Yu, S.1
Levi, L.2
Siegel, R.3
Noy, N.4
-
63
-
-
34648816863
-
Retinoic acid in the development, regeneration and maintenance of the nervous system
-
M. Maden, "Retinoic acid in the development, regeneration and maintenance of the nervous system," Nature Reviews Neuroscience, vol. 8, no. 10, pp. 755-765, 2007.
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.10
, pp. 755-765
-
-
Maden, M.1
-
64
-
-
39549091493
-
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein e4 in primary cortical neurons
-
J. Brodbeck, M. E. Balestra, A. M. Saunders, A. D. Roses, R.W. Mahley, and Y. Huang, "Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons," Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 4, pp. 1343-1346, 2008.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.4
, pp. 1343-1346
-
-
Brodbeck, J.1
Balestra, M.E.2
Saunders, A.M.3
Roses, A.D.4
Mahley, R.W.5
Huang, Y.6
-
65
-
-
29444436680
-
Lipid-And receptor-binding regions of apolipoprotein e4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
-
S. Chang, T. R. Ma, R. D. Miranda, M. E. Balestra, R. W. Mahley, and Y. Huang, "Lipid-And receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity," Proceedings of theNational Academy of Sciences of the United States of America, vol. 102, no. 51, pp. 18694-18699, 2005.
-
(2005)
Proceedings of TheNational Academy of Sciences of the United States of America
, vol.102
, Issue.51
, pp. 18694-18699
-
-
Chang, S.1
Ma, T.R.2
Miranda, R.D.3
Balestra, M.E.4
Mahley, R.W.5
Huang, Y.6
-
66
-
-
12144290271
-
Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice
-
W. J. Brecht, F. M. Harris, S. Chang et al., "Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice," Journal of Neuroscience, vol. 24, no. 10, pp. 2527-2534, 2004.
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.10
, pp. 2527-2534
-
-
Brecht, W.J.1
Harris, F.M.2
Chang, S.3
-
68
-
-
0029417191
-
Rat ppar? Contains a cggtriplet repeat and is prominently expressed in the thalamic nuclei
-
G. Xing, L. Zhang, T. Heynen et al., "Rat PPAR? contains a CGGtriplet repeat and is prominently expressed in the thalamic nuclei," Biochemical and Biophysical Research Communications, vol. 217, no. 3, pp. 1015-1025, 1995.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.217
, Issue.3
, pp. 1015-1025
-
-
Xing, G.1
Zhang, L.2
Heynen, T.3
-
69
-
-
33847093475
-
Thiazolidinedione class of peroxisome proliferator-Activated receptor agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
-
S. Park, J. Yi, G. Miranpuri et al., "Thiazolidinedione class of peroxisome proliferator-Activated receptor agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats," Journal of Pharmacology and Experimental Therapeutics, vol. 320, no. 3, pp. 1002-1012, 2007.
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.3
, pp. 1002-1012
-
-
Park, S.1
Yi, J.2
Miranpuri, G.3
-
70
-
-
34547107881
-
Ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-Activated receptor
-
A. L. B. Ambrosio, S. M. G. Dias, I. Polikarpov, R. B. Zurier, S. H. Burstein, and R. C. Garratt, "Ajulemic acid, a synthetic nonpsychoactive cannabinoid acid, bound to the ligand binding domain of the human peroxisome proliferator-Activated receptor ," Journal of Biological Chemistry, vol. 282, no.25, pp. 18625-18633, 2007.
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18625-18633
-
-
Ambrosio, A.L.B.1
Dias, S.M.G.2
Polikarpov, I.3
Zurier, R.B.4
Burstein, S.H.5
Garratt, R.C.6
-
71
-
-
45549087654
-
Intrathecal rosiglitazone acts at peroxisome proliferator-Activated receptor- to rapidly inhibit neuropathic pain in rats
-
S. B.Churi,O. S.Abdel-Aleem, K. K. Tumber,H. Scuderi-Porter, and B. K. Taylor, "Intrathecal rosiglitazone acts at peroxisome proliferator-Activated receptor- to rapidly inhibit neuropathic pain in rats," Journal of Pain, vol. 9, no. 7, pp. 639-649, 2008.
-
(2008)
Journal of Pain
, vol.9
, Issue.7
, pp. 639-649
-
-
Churi, S.B.1
Abdel-Aleem, O.S.2
Tumber, K.K.3
Scuderi-Porter, H.4
Taylor, B.K.5
-
72
-
-
84876965338
-
Ppar activation blocks development and reduces established neuropathic pain in rats
-
J.Morgenweck, R. B. Griggs, R. R.Donahue, J. E. Zadina, and B. K. Taylor, "PPAR activation blocks development and reduces established neuropathic pain in rats," Neuropharmacology, vol. 70, pp. 236-246, 2013.
-
(2013)
Neuropharmacology
, vol.70
, pp. 236-246
-
-
Morgenweck, J.1
Griggs, R.B.2
Donahue, R.R.3
Zadina, J.E.4
Taylor, B.K.5
-
73
-
-
56649116084
-
Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury
-
T.Maeda, N. Kiguchi, Y. Kobayashi, M. Ozaki, and S. Kishioka, "Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury," Journal of Pharmacological Sciences, vol. 108, no. 3, pp. 341-347, 2008.
-
(2008)
Journal of Pharmacological Sciences
, vol.108
, Issue.3
, pp. 341-347
-
-
Maeda, T.1
Kiguchi, N.2
Kobayashi, Y.3
Ozaki, M.4
Kishioka, S.5
-
74
-
-
72049114712
-
Activation of peroxisome proliferator-Activated receptor in brain inhibits inflammatory pain, dorsal horn expression of fos, and local edema
-
J. Morgenweck, O. S. Abdel-Aleem, K. C. McNamara, R. R. Donahue, M. Z. Badr, and B. K. Taylor, "Activation of peroxisome proliferator-Activated receptor in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema," Neuropharmacology, vol. 58, no. 2, pp. 337-345, 2010.
-
(2010)
Neuropharmacology
, vol.58
, Issue.2
, pp. 337-345
-
-
Morgenweck, J.1
Abdel-Aleem, O.S.2
McNamara, K.C.3
Donahue, R.R.4
Badr, M.Z.5
Taylor, B.K.6
-
75
-
-
75749127323
-
A molecularmechanismfor ibuprofen-mediated rhoa inhibition in neurons
-
J.Dill, A. R. Patel, X. Yang,R.Bachoo, C.M. Powell, and S. Li, "A molecularmechanismfor ibuprofen-mediated RhoA inhibition in neurons," Journal of Neuroscience, vol. 30, no. 3, pp. 963-972, 2010.
-
(2010)
Journal of Neuroscience
, vol.30
, Issue.3
, pp. 963-972
-
-
Dill, J.1
Patel, A.R.2
Yang, X.3
Bachoo, R.4
Powell, C.M.5
Li, S.6
-
76
-
-
84866322573
-
Peroxisome proliferator-Activated receptor-gamma agonist rosiglitazone attenuates postincisional pain by regulating macrophage polarization
-
M. Hasegawa-Moriyama, T. Ohnou, K. Godai, T. Kurimoto,M. Nakama, and Y. Kanmura, "Peroxisome proliferator-Activated receptor-gamma agonist rosiglitazone attenuates postincisional pain by regulating macrophage polarization," Biochemical and Biophysical Research Communications, vol. 426, no. 1, pp. 76-82, 2012.
-
(2012)
Biochemical and Biophysical Research Communications
, vol.426
, Issue.1
, pp. 76-82
-
-
Hasegawa-Moriyama, M.1
Ohnou, T.2
Godai, K.3
Kurimoto, T.4
Nakama, M.5
Kanmura, Y.6
-
77
-
-
84879785605
-
Peroxisome proliferator-Activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages
-
M. Hasegawa-Moriyama, T. Kurimoto, M. Nakama et al., "Peroxisome proliferator-Activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages," Pain, vol. 154, no. 8, pp. 1402-1412, 2013.
-
(2013)
Pain
, vol.154
, Issue.8
, pp. 1402-1412
-
-
Hasegawa-Moriyama, M.1
Kurimoto, T.2
Nakama, M.3
|