Amelioration of oxidative stress and protection against early brain injury by astaxanthin after experimental subarachnoid hemorrhage: Laboratory investigation

Journal of Neurosurgery

Volumn 121, Issue 1, 2014, Pages 42-54

  Zhang, Xiang Sheng ^a   Zhang, Xin ^a,b   Zhou, Meng Liang ^b   Zhou, Xiao Ming ^a   Li, Ning ^a   Li, Wei ^b   Cong, Zi Xiang ^b   Sun, Qing ^b   Zhuang, Zong ^b   Wang, Chun Xi ^b   Shi, Ji Xin ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Astaxanthin; Early brain injury; Oxidative stress; Rabbit; Rat; Subarachnoid hemorrhage; Vascular disorders

Indexed keywords

ASTAXANTHIN; CASPASE 3; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN EDEMA; BRAIN INJURY; CELL COUNT; CONTROLLED STUDY; DISEASE SEVERITY; DRUG MEGADOSE; EXPERIMENTAL HEMORRHAGE; EXPERIMENTAL RABBIT; EXTRAVASATION; HISTOPATHOLOGY; IMMUNOREACTIVITY; LOW DRUG DOSE; MALE; MEMBRANE PERMEABILITY; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NISSL STAINING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBARACHNOID HEMORRHAGE; WEIGHT REDUCTION; WESTERN BLOTTING;

ASTAXANTHIN; ATX = ASTAXANTHIN; BBB = BLOOD-BRAIN BARRIER; DAB = 3,3′-DIAMINOBENZIDINE; EARLY BRAIN INJURY; EB = EVANS BLUE; EBI = EARLY BRAIN INJURY; GAPDH = GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; GSH = GLUTATHIONE; H2O2 = HYDROGEN PEROXIDE; MDA = MALONDIALDEHYDE; OXIDATIVE STRESS; PBS = PHOSPHATE-BUFFERED SALINE; RABBIT; RAT; SAH = SUBARACHNOID HEMORRHAGE; SOD = SUPEROXIDE DISMUTASE; SUBARACHNOID HEMORRHAGE; TBS-T = TRIS-BUFFERED SALINE WITH TWEEN 20; VASCULAR DISORDERS;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; MALE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SUBARACHNOID HEMORRHAGE; XANTHOPHYLLS;

EID: 84902251257     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.2.JNS13730     Document Type: Article

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